Advances in Materials Science and Engineering
·
2022
·Vol. 2022
·期 1
·7408284
·
IF 2.098
Zhenhao Wei,Yufan Ji,Yiping Huang,Jingjing Huang,Yunguo Huang,Changhai Yue,Junzhou Li,Mingwei Tang,Yunfang Liu,Hanfei Liu,Hao Zhu,Kai Zhu,Fan Yang,Xuedong Zhu
Zinc (Zn) and cerium (Ce) modified hierarchical ZSM-5 (HZ) catalysts were prepared by incipient wetness impregnation, and their catalytic performances in methanol to aromatics reaction were evaluated in a fixed-bed reactor operating at 400°C under 0.1 MPa and WHSV of 1.0 h −1 . The structure, acidity, and state of Zn species of the Zn/Ce modified HZ catalysts were investigated via several characterization techniques, including XRD, NH 3 -TPD, H 2 -TPR, nitrogen adsorption, and XPS. The results showed that the aromatization activity of 2 wt% Zn-modified HZ (2% Zn/HZ) could be significantly enhanced by loading 0.6 wt% Ce, which was mainly attributed to the increase in surface ZnOH + species. Moreover, it was found that Ce inhibited pore blockage caused by Zn. Consequently, compared to 2% Zn/HZ, 2% Zn-0.6% Ce/HZ exhibited higher aromatic selectivity and longer catalyst lifetime.
研究领域:
催化化学
·
材料科学
✓ 已验证
DOI
高影响因子
Reaction Chemistry & Engineering
·
2025
·
IF 3.1
Wei Qi,Yuqi Chen,Liangzhi Li,Xin Ju,Hongwei Chen,Lishi Yan
The catalytic conversion of fructose to 5-hydroxymethylfurfural (5-HMF) in ternary deep eutectic solvent (DES)/methyl isobutyl ketone (MIBK) biphasic system at mild temperatures (50~70 ℃) was investigated in this work. The ternary DES consists of choline chloride (ChCl), benzene sulfonic acid (BSA) and ethylene glycol (EG) were physiochemical characterized by FT-IR and 1H NMR. The ternary DES(ChCl-BSA-EG)/MIBK biphasic system (ChCl/BSA/EG=2:1:1) resulted in 82.0% 5-HMF yield and 96.2% corresponding selectivity at 60 °C for 2 h. The kinetic analysis further revealed that the rate constant of fructose dehydration (k1) was much higher than the rate constant of 5-HMF conversion (k2). The calculated ratio of k1/k2 was 16.1. The proposed reaction mechanism suggested that the synergetic effect of the three components of ternary DES facilitates the elimination of water molecules from fructose and the formation of 5-HMF, while the MIBK extraction phase suppress the byproducts of 5-HMF as well. The present work provides a green and sustainable pathway for 5-HMF production with high yield and high selectivity at mild temperatures.
研究领域:
化学工程
·
绿色化学
✓ 已验证
产品关联
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Mengyuan Qiu,Yongzhi Xiong,Wei Zhao,Dong Ouyang,Zongxuan Wu,Tangtianxiang Liang,Changzhou Chen,Shengchun Hu,Hao Sun
Designing low-cost, high-performance electrocatalysts for the electrocatalytic oxidation of 5-hydroxymethylfurfural (HMF) to produce 2,5-furandicarboxylic acid (FDCA) remains a significant challenge. Herein, we report a novel post-pyrolysis phosphidation method for preparing Nb- and Fe-doped CoP-based catalysts. Nb-CoP@NC delivers a current density of 91.79 mA cm⁻² at a potential of only 1.50 V vs. RHE, achieving nearly 100 % HMF conversion, 98.3 % FDCA selectivity, and 95.6 % Faradaic efficiency (FE). Structural and surface analyses via XRD and XPS reveal that Nb doping significantly modulates the electronic structure of CoP, generating Nb 5+δ active species, which show superior catalytic activity for HMFOR compared to Fe 3+δ . This work not only highlights the pivotal role of Nb doping in enhancing catalytic performance but also provides a general and facile strategy for constructing efficient bimetallic CoP-based catalysts for biomass-derived HMF oxidation.
研究领域:
催化
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电化学
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生物质转化
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材料科学
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绿色化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CHEMICAL RESEARCH
·
2017
·
IF 0.646
Da-Hua Shi,Hui-Long Zhu,Yu-Wei Liu,Zong-Ming Tang,Chen Lu,Xiao-Dong Ma,Xiao-Kai Song,Wei-Wei Liu,Tong Dong,Meng-Qiu Song
Three novel 5-benzyl-1,3,4-thiadiazole derivatives were synthesised starting from phenylacetic acid derivatives. These compounds were characterised by NMR, HRMS and single-crystal X-ray diffraction analysis. 2-Pyrrolidyl-5-[2-(4-bromophenyl)methyl]-1,3,4-thiadiazole showed moderate acetylcholinesterase-inhibition activity with a 50% inhibitory concentration value of 33.16 μM. 2-Pyrrolidyl-5-[2-(4-bromophenyl)methyl]-1,3,4-thiadiazole and acetylcholinesterase docking was demonstrated using the Molecular Operating Environment program.
研究领域:
药物化学
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神经生物学
·
有机化学
✓ 已验证
DOI
高影响因子
ACS Applied Bio Materials
·
2022
·
IF 0
Chun-Xia Zhang,Hong-Wei Li,Renwen Zhang,Zhongyuan Ren,Yuqing Wu
In the present work, cytidine 5′-monophosphate capped gold nanoclusters (AuNCs@CMP) are reported as a catalyst for redox reactions, which show both oxidase- and excellent peroxidase-like activity. When employing 3,3′,5,5′-tetramethylbenzidine (TMB) as a substrate in the presence of hydrogen peroxide (H2O2), the maximum velocity (Vmax) was 175 × 10–8 M s–1in vitro. Besides, the AuNCs@CMP exhibited high catalytic activity for reactive oxygen species (ROS) generation with H2O2. Particularly, they also displayed excellent catalytic activity for ROS generation in tumor cells, being activated and promoted by the tumor microenvironment (TME). Consequently, the AuNCs@CMP show an excellent antitumor effect on HeLa and SW480 cells as assayed by flow cytometry. The antitumor mechanism of AuNCs@CMP was attributed to the high ROS generation based on the specific environments of the TME. Therefore, the present study provides TME-adaptive AuNCs@CMP with excellent mimetic peroxidase activity, producing significant ROS to kill the tumor cells in TME.
研究领域:
纳米医学
·
肿瘤学
·
催化
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生物化学
✓ 已验证
DOI
PubMed
FOOD CHEMISTRY
·
2015
·
IF 3.391
Zhenhua Zhang,Yueyu Zou,Taigang Wu,Caihuan Huang,Kehan Pei,Guangwen Zhang,Xiaohua Lin,Weibin Bai,Shiyi Ou
Chlorogenic acid (CGA) is a phenolic acid that ubiquitously exists in fruits. This work aims to investigate whether and how CGA influences HMF formation during heating fructose alone, or with an amino acid. The results showed that that CGA increased 5-hydroxymethylfurfural (HMF) formation. At pH 5.5 and 7.0, the addition of 5.0 μmol/ml CGA increased HMF formation by 49.4% and 25.2%, respectively when heating fructose alone, and by 9.0% and 16.7%, respectively when heating fructose with aspartic acid. CGA significantly increased HMF formation by promoting 3-deoxosone formation, and its conversion to HMF by inhibiting HMF elimination, especially in the Maillard reaction system. A comparison of the catalytic capacity of CGA with its six analogous compounds showed that both its di-hydroxyphenyl and carboxyl groups function in increasing HMF formation.
研究领域:
食品科学
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化学
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Jinghua Wang,Hongyou Cui,Jiangang Wang,Zhihe Li,Ming Wang,Weiming Yi
Conversion of glucose to 5-hydromethyl furfural (HMF) and levulinic acid (LA) was systematically investigated in LiCl·3H 2 O without additional catalyst. Based on the experimental investigations by using glucose, fructose and HMF as the reaction substrate separately, corresponding reaction kinetics in LiCl·3H 2 O were modelled by first-order assumption. Kinetic analysis demonstrates that high temperature favors the formation of LA, while low temperature facilitates to selectively form humins. To achieve high LA yield, at least a temperature of 140 °C is required. Without additional catalyst converting glucose to LA in LiCl·3H 2 O, humins was predominantly derived from glucose and HMF, and glucose isomerization is the reaction rate-determining step. The activation energies of the main reactions are 160.96 kJ/mol (glucose to HMF), 139.20 kJ/mol (fructose to HMF), and 71.81–76.48 kJ/mol (HMF to LA) respectively. The activation energies for humins formation were 23.45 kJ/mol from glucose, 49.54 kJ/mol from fructose, and 42.15–65.85 kJ/mol from HMF, respectively. It is verified that LiCl·3H 2 O, as compared to aqueous medium, is an excellent reaction medium for converting glucose to LA as it can provide the active centers for fructose to HMF reaction and HMF to LA reaction, but lack of highly efficient Lewis acid for glucose isomerization. With the addition of Lewis acid (such as AlCl 3 and FeCl 3 ), as high as 83.4% of LA yield can be obtained respectively when directly converting glucose, with the total selectivities of LA and HMF of 95%.
研究领域:
生物化学
·
催化化学
✓ 已验证
DOI
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2025
·
IF 21.1
Weizhen Xie,Chenting Yang,Quanwei Deng,Shigang Su,Lu Lin,Xing Tang
The selective hydrogenation of biomass-derived 5-hydroxymethylfurfural (HMF) to 2,5-bis(hydroxymethyl)tetrahydrofuran (BHMTHF) under mild conditions holds great significance for sustainable chemical production. However, this process remains hindered by challenges such as the instability of HMF in aqueous media and the insufficient efficiency of H 2 activation. Herein, a Pd catalyst supported on oxygen-vacancy–enriched MnO x -VC (Pd/MnO x -VC) is developed, featuring highly dispersed Pd/PdO heterostructures with abundant Pd–O–Mn interfacial active sites. Notably, Pd/MnO x -VC offered a high BHMTHF formation rates of 366.5 mol BHMTHF ·mol Pd −1 ·h −1 in water under mild conditions. Moreover, the catalyst was able to efficiently convert both purified and crude HMF at high concentrations (≥ 10 wt%), achieving BHMTHF yields exceeding 90 % in either batch or continuous-flow reactor under low temperatures (30–60 °C), underscoring its potential for industrial application. Mechanistic studies revealed that the relay activation of H 2 over Pd nanoparticles and adjacent Pd–O–Mn sites generates polarized H δ⁺ –H δ⁻ pairs, which primarily contributed to the outstanding activity of Pd/MnO x -VC. This work highlights the importance of interfacial site engineering in designing high-performance catalysts for HMF hydrogenation.
研究领域:
催化化学
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生物质转化
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绿色化学
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材料化学
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应用化学
✓ 已验证
产品关联
DOI
高影响因子
APPLIED CATALYSIS A-GENERAL
·
2018
·
IF 4.521
Jingjie Cao,Mingwei Ma,Jinchan Liu,Yongquan Yang,Hui Liu,Xingliang Xu,Jiahui Huang,Huijuan Yue,Ge Tian,Shouhua Feng
Aluminum ion-exchanged Ca-montmorillonite with different concentrations of aluminum ion were prepared and applied in the conversion of carbohydrates to 5-hydroxymethylfurfural (HMF). It was found that two types of acid sites were present in the catalyst, Lewis acid sites for isomerization of glucose and Brønsted acid sites for dehydration of fructose. With Al-mont-10 as catalyst, the yield of HMF converted from glucose was 80.4% in a biphase system (THF: NaCl solution) at 180 °C for 2.5 h. Further, the catalyst also shows excellent catalytic performance in the conversion of starch and inulin, and the yield of HMF reached 60.1% and 81.6% under identical conditions, respectively.
研究领域:
化学工程
·
催化科学
✓ 已验证
DOI
高影响因子
ChemCatChem
·
2016
·Vol. 8
·期 23
·3636-3643
·
IF 4.724
Zhenyou Gui,Wenrong Cao,Shunmugavel Saravanamurugan,Anders Riisager,Lifang Chen,Zhiwen Qi
Graphical Efficient noble alloy : Au–Pd supported on zinc hydroxycarbonate (ZOC) catalysts shows high activity for 5-hydroxymethylfurfural oxidation. The basicity of ZOC can play a crucial role in enhancing the yield of FDCA. Moreover, Au–Pd/ZOC can be recycled at least six times without significant loss of its activity. Bimetallic catalysts with Au–Pd supported on zinc hydroxycarbonate (ZOC) were synthesized by a simple deposition–precipitation method and analyzed by transmission electron microscopy to have a narrow-size distribution of predominantly 1–2 nm. The prepared Au–Pd/ZOC catalysts exhibited excellent activity towards 5-hydoxymethylfurfural (HMF) oxidation in water in the presence of the base NaHCO 3 at benign conditions of 80 °C and 3 bar O 2 , resulting in quantitative yield of 2,5-furandicarboxylic acid (FDCA). The addition of base not only enhanced the yield of FDCA but also stabilized the support ZOC by preventing ZOC from the reaction with formed carboxylic acid intermediates/products, thus allowing Au–Pd/ZOC to be recycled for at least six times without significant loss of activity. The basicity of ZOC could play an important role in obtaining the improved yield of FDCA as compared to other supports.
研究领域:
催化化学
·
绿色化学
·
化学工程
·
材料科学
·
有机合成
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环境科学
✓ 已验证
DOI
高影响因子
BIOORGANIC CHEMISTRY
·
2021
·
IF 5.275
Fang Guo,Tao Xia,Ping Xiao,Qingyue Wang,Zhitong Deng,Wang Zhang,Guowang Diao
Pillar[5]arene complexes of the naturally occurring compound bisdemethoxycurcumin (BDMC) were acquired for improving the water solubility and stability of BDMC. As a family member of curcuminoid compounds, BDMC has many interesting therapeutic properties. However, its low aqueous solubility and stability resulted in poor availability and restricted the clinical efficacy. Pillar[5]arenes with hydrophilic ends and a hydrophobic cavity could include with BDMC based on size matching. The synthesized hydrazide-pillar[5]arene (HP5A) and BDMC had a strong host–guest interaction with a 1:1 binding stoichiometry. Furthermore, the HP5A ⊃ BDMC complex could self-assemble into well-defined fibers in water/ethanol solution. This supramolecular complex worked well in vitro for inhibiting the proliferation of hepatoma carcinoma cells HepG2. Remarkably, this method of complexation with pillar[5]arenes visibly reduced the undesirable side effects on normal cells without weakening the anti-cancer activity of the drugs. We expected that the obtained host–guest complex and fibrous assembly would provide a promising platform for delivering drugs with low water solubility.
研究领域:
药物化学
·
肿瘤学
·
超分子化学
✓ 已验证
DOI
PubMed
高影响因子
Catalysts
·
2016
·Vol. 6
·期 9
·134
·
IF 2.964
Songbai Qiu,Ying Xu,Yujing Weng,Longlong Ma,Tiejun Wang
A series of MCM-41 supported Ni catalysts with high metal dispersion was successfully synthesized by simple co-impregnation using proper ethylene glycol (EG). The acquired Ni-based catalysts performed the outstanding hydrogenolysis activity of guaiacol. The effects of the synthesis parameters including drying temperature, calcination temperature, and metal loading on the physical properties of NiO nanoparticles were investigated through the use of X-ray diffraction (XRD). The drying temperature was found to significantly influence the particle sizes of NiO supported on MCM-41, but the calcination temperature and metal loading had less influence. Interestingly, the small particle size (≤3.3 nm) and the high dispersion of NiO particles were also obtained for co-impregnation on the mixed support (MCM-41:HZSM-5 = 1:1), similar to that on the single MCM-41 support, leading to excellent hydrogenation activity at low temperature. The guaiacol conversion could reach 97.9% at 150 °C, and the catalytic activity was comparative with that of noble metal catalysts. The hydrodeoxygenation (HDO) performance was also promoted by the introduction of acidic HZSM-5 zeolite and an 84.1% yield of cyclohexane at 240 °C was achieved. These findings demonstrate potential applications for the future in promoting and improving industrial catalyst performance.
研究领域:
催化化学
·
能源化学
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材料化学
·
工业催化
·
生物质转化
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）