BIOELECTROCHEMISTRY
·
2019
·
IF 4.474
Shuan Zhang,Chunyan Zhang,Yilei Jia,Xiaobo Zhang,Yunhui Dong,Xinjin Li,Qing Liu,Yueyun Li,Zengdian Zhao
A sandwich-type electrochemical immunosensor was fabricated for the quantitation of alpha fetoprotein (AFP). To this end, the Au@Pt dendritic nanorods loaded with amino functionalized molybdenum selenide nanosheets (Au@Pt 41 DNRs/NH2-MoSe2 NSs) with enhanced peroxidase-like properties were selected as the secondary antibody label (Ab2) to achieve signal amplification. The as-obtained Au@Pt DNRs/NH2-MoSe2 NSs exhibited better catalytic activity toward hydrogen peroxide reduction and offered rich anchors for bioconjugation . Meanwhile, gold nanoparticles anchored on an amino functionalized graphene (Au NPs/NH2-GS) composite with admirable conductivity and biocompatibility was used as the matrix material to improve sensitivity. Under optimal conditions, amperometric current responses had a good linear relationship with the logarithm values of AFP concentration in the range 10 fg mL –1 to 200 ng mL –1 with a detection limit of 3.3 fg mL –1 (S/N = 3). Additionally, the immunosensor had excellent reproducibility, selectivity, and stability, which indicated superior performance for AFP detection compared with previous reports. The satisfactory results of human serum samples analysis showed that the designed immunosensor has potential applicability for the sensitive detection of other tumor markers.
研究领域:
分析化学
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生物化学
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纳米技术
·
医学诊断
✓ 已验证
DOI
高影响因子
Nano Energy
·
2018
·
IF 13.12
Hui Liu,Beihong Liu,Hong Guo,Mengfang Liang,Yuhao Zhang,Timur Borjigin,Xiaofei Yang,Lin Wang,Xueliang Sun
To meet the pressing needs of fast development of energy and environmental science, sodium ion batteries (SIBs) are considered as the promising novel generation of power storage system, due to abundant reserves and low price of sodium sources. In this work, N-doped C-encapsulated scale-like yolk-shell structured MoSe 2 -C materials assembled by expanded (002) planes few-layer MoSe 2 nanosheets are successfully synthesized by a facile general strategy. The few-layer crystal fringes are no more than 4 layers. Notably, the interlayer spacing of (002) planes is expanded to 1.15 nm, which is larger than its intrinsic value of pristine MoSe 2 (0.64 nm). Particularly, the few-layer nanosheets with expanded (002) planes are spaced-restricted growing in the inner wall and the surface of hollow carbon frame and form scale-like yolk-shell hybrid MoSe 2 -C structure. When evaluated as anode for SIBs, the MoSe 2 -C materials show ultra-long cycling life, maintaining 378 mA h g −1 over 1000 cycles at 3 A g −1 . It also exhibits outstanding rate capability and the Coulombic efficiencies for all the rate performance reaching more than 98.3% except the first one. The expanded (002) planes, 2D fewer-layer nanosheets and unique N-doped C-encapsulated scale-like yolk-shell frame are responsible for the enhanced electrochemical performance.
✓ 已验证
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2022
·Vol. 46
·期 10
·4666-4676
·
IF 3.925
Wei Ma,Binghua Yao,Qian Yang,Ting Zhang,Kecong Tian,Wen Zhang,Jinfen Niu,Yan Yu,Zheng Chang,Yangqing He
In this study, ultrathin MoSe2 nanosheets (MoSe2 NSs) with enriched selenium vacancies (Se-vacancies) were prepared via a HNO3-assisted exfoliation strategy. The features of the synthesized catalysts were characterized via SEM, TEM, XRD, EPR, Raman spectroscopy, XPS, BET, EIS, PFM and contact angle tests. The results showed that the optimum MoSe2 NSs-10 with an enlarged specific surface area had superior hydrophilicity and conductivity. Meanwhile, MoSe2 NSs-10 showed typical butterfly-shaped amplitude curves and 150° polar domain switching, which confirmed its out-of-plane ferroelectricity. This out-of-plane polarization originated from the unique AB stacking mode of the MoSe2 NSs, contributing to the polarization enhancement. These superior properties of MoSe2 NSs-10 were responsible for its enhanced piezocatalytic degradation efficiency of tetracycline (TC) compared with that of pristine MoSe2 nanoflowers (NFs). Under ultrasonic irradiation, 93.9% TC was degraded by MoSe2 NSs-10 within 30 s, which was over 3.6-fold higher than that by the MoSe2 NFs. Additionally, the active species trapping tests and electron spin resonance (ESR) measurements proved that both hydroxyl radicals (˙OH) and superoxide radicals (˙O2−) participated in the degradation of TC as major active species. The degradation pathways of TC over the MoSe2 NSs-10 piezocatalytic system were proposed based on HPLC-MS analysis. This work provides a new approach for improving the piezocatalytic performance of MoSe2 piezocatalysts towards antibiotic wastewater treatment.
研究领域:
材料科学
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环境科学
·
化学
✓ 已验证
产品关联
DOI
高影响因子
MATERIALS RESEARCH BULLETIN
·
2021
·
IF 4.641
Yanhua Yao,Changhai Liu,Linlin Luo,Dingwei Ji,Wenchang Wang,Zhidong Chen
To enhance the intrinsic activity and the density of active sites of the electrocatalyst for the hydrogen evolution reaction (HER), the microwave-assisted synthesis is adopted to prepare hierarchical Ce-doped MoSe 2 @CNTs as highly-efficient catalysts for HER in both acidic and alkaline conditions. The well-defined hierarchical nanostructure of Ce-doped MoSe 2 on multiple carbon nanotubes (MWCNTs) with few layers of MoSe 2 nanostructure. The Ce-MoSe 2 @CNTs sample with an optimal proportion of Ce:Mo (1:5) exhibits outstanding activity and long-term stability in both acidic and alkaline electrolyte. It shows an overpotential of 108 and 166 mV at 10 mA cm −2 in acidic and alkaline electrolyte, respectively. This study offers a prospective opportunity to design and fabricate the highly-effective catalysts coupling with multiple synergistic effect for efficient electrocatalysts.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Nano Materials
·
2024
·
IF 5.3
Hui Zhang,Xuelin You,Ruihan Liu,You Wang,Fang Han,Juanyuan Hao,Yu Li
Cuproptosis efficiency is severely limited by insufficient Cu+ contents in tumors due to the easy oxidation of Cu+ into Cu2+ and the copper efflux mechanism. Herein, we develop a copper nanocarrier (MoSe2/CuO2) that can significantly enhance intracellular Cu+ for self-boosting cuproptosis-based synergistic antitumor therapy. Upon endocytosis by cancer cells, the acidic tumor microenvironment (TME) triggers the degradation of MoSe2/CuO2 to release Cu2+. MoSe2 then acts as a cocatalyst that promotes the reduction of released Cu2+ to Cu+, while oxidizing active Mo4+ to Mo6+, thereby triggering cuproptosis. Importantly, the produced Mo6+ is further returned to Mo4+ by endogenous glutathione (GSH) depletion, enhancing the cocatalytic effects of MoSe2 and resulting in a continuous Cu+ generation for self-boosting cuproptosis. Meanwhile, GSH-enhanced cocatalysis and MoSe2-mediated photothermal effect can significantly promote Cu-Fenton reactions, which not only downregulate Cu-ATPase to reduce Cu+ efflux and aggravate cuproptosis with higher efficacy but also activate caspase-3 to promote cell apoptosis. MoSe2/CuO2 exhibits excellent antitumor effects (94.9% tumor growth inhibition) and biosafety effects in vitro and in vivo. This work presents a strategy that enables high levels of Cu+ delivery by enhancing generation and reducing efflux for self-boosting cuproptosis–apoptosis synergistic therapy.
研究领域:
纳米技术
·
癌症研究
·
生物医学工程
·
治疗学
✓ 已验证
产品关联
DOI
高影响因子
Solar RRL
·
2019
·Vol. 3
·期 10
·1900131
·
IF 0
Afei Zhang,Zhengji Zhou,Wenhui Zhou,Dongxing Kou,Yuena Meng,Yafang Qi,Shengjie Yuan,Sixin Wu
A back contact interface in a kesterite Cu 2 ZnSn(S,Se) 4 (CZTSSe) photovoltaic device plays an important role in fabricating high quality semiconducting photoactive layers and improving carrier extraction efficiency. However, uncontrolled decomposition reactions between the CZTSSe absorber layer and Mo electrode result in high series resistance and recombination at the back interface. The insertion of high work function MoO 3 as an interfacial layer is considered as a promising way to engineer the back contact. This highlights the importance of elucidating the chemistry and dynamics of MoO 3 at the Mo/kesterite interface in the CZTSSe annealing process. Herein, A detailed investigation of the elemental diffusion and chemistry of the back contact with the MoO 3 intermediate layer during selenization is carried out. The results demonstrate that the presence of the MoO 3 interfacial layer largely suppresses the chemical reaction between Mo and CZTSSe in the annealing process, inducing high quality CZTSSe absorbing films with fewer voids and reducing the thickness of MoSe 2 from 209 to 84 nm when the optimized thickness of MoO 3 is 10 nm. This finally leads to the increase in device efficiency from 9.02% to 10.92%, and the best performance where an efficiency of 11.37% is achieved.
研究领域:
材料科学
·
光伏技术
·
半导体物理
·
太阳能电池技术
✓ 已验证
产品关联
DOI
ACS Applied Materials & Interfaces
·
2019
·
IF 8.456
Yanping Song,Bin Yao,Yongfeng Li,Zhanhui Ding,Huanhuan Sun,Zhenzhong Zhang,Ligong Zhang,Haifeng Zhao
Cu2ZnSn(S,Se)4 (CZTSSe) thin-film solar cells have been encountering a bottleneck period since the champion power conversion efficiency (PCE) of 12.7% was achieved by Kim et al. in 2014. One of the critical factors that impede its further development is the relatively low open-circuit voltage (VOC) caused by serious interface carrier recombination. In this regard, back surface field (BSF) employment is a feasible strategy to address the VOC issue of CZTSSe solar cells to some extent. Here, we demonstrated a self-organized BSF introduced by prompting interfacial MoSe2 layer transition from inherent n-type to desirable p-type with Nb doping (p-MoSe2:Nb). The BSF application can significantly reduce the carrier recombination at the back electrode interface (BEI) and lower down the back contact barrier height. The PCE of the corresponding cell was improved from 4.72 to 7.15% because of the enhancement of VOC and fill factor, primarily stemming from the doubling aspects of increased shunt resistance (RSh), decreased series resistance (RS), and alleviative recombination velocity of the BEI induced by the BSF. Our results suggest that introducing a BSF fulfilled with p-MoSe2:Nb is a facile and promising route to improve the performance of CZTSSe thin-film solar cells.
研究领域:
光伏技术
·
薄膜太阳能电池
·
半导体材料
·
材料科学
·
可再生能源
✓ 已验证
DOI
高影响因子
SOLAR ENERGY
·
2024
·
IF 6
Letu Siqin,Chenjun Yang,Jingyuan Guo,Yutian Wang,Lei Wang,Yuan Li,Yiming Wang,Shuyu Li,Xiangyu Chen,Hongmei Luan,Ruijian Liu,Chengjun Zhu
The high open-circuit voltage deficit (V OC, def ) caused by structural imperfections in the absorber layer and charge loss during carrier transport is a critical barrier affecting the performance of Cu 2 ZnSn(S,Se) 4 (CZTSSe) devices. In this work, Ag was added to the DMF-based Cu + -Sn 4+ system, which significantly improved the crystal morphology and electrical properties of the absorber layer. Additionally, optimizing the selenization process not only reduced surface roughness and eliminated voids at the bottom of the absorber layer but also resulted in the formation of a MoSe 2 back interface layer with a more suitable thickness. These measures collectively enhanced the overall quality of the absorber layer, reducing the formation of deep-level defect clusters and effectively boosting carrier transport efficiency. Consequently, the concentration of bulk and interfacial defects decreased, and the impact of potential barriers on carrier movement was minimized. With these comprehensive improvements, the power conversion efficiency of CZTSSe solar cells increased from 8.48 % to 11.23 %. Our research demonstrates that optimizing the structure of the absorber layer can effectively enhance the performance of CZTSSe solar cells, providing valuable insights for the fabrication of high-efficiency devices in the future.
研究领域:
材料科学
·
太阳能
·
半导体物理
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）