Materials Science & Engineering C-Materials for Biological Applications
·
2017
·
IF 4.164
Long Huang,Meiying Liu,Liucheng Mao,Xiqi Zhang,Dazhuang Xu,Qing Wan,Qiang Huang,Yingge Shi,Fengjie Deng,Xiaoyong Zhang,Yen Wei
In recent years, aggregation-induced emission (AIE) dyes based fluorescent organic nanoparticles (FONs) have achieved significant progress in various biomedical applications. In this work, we developed a covalent strategy to prepare biocompatible AIE-active dyes based cross-linked copolymers (MPC-POSS-PhE) via controllable reversible addition fragmentation chain transfer (RAFT) polymerization using zwitterionic 2-methacryloyloxyethyl phosphorylcholine (MPC), polymerizable AIE dye (named as PhE) and 8-vinyl polyoctahedral silsesquioxanes (POSS) as monomers. Due to the existence of hydrophilic MPC and hydrophobic PhE, the resultant copolymers will self-assemble into core-shell nanoparticles in aqueous solution with ultra-low critical micelle concentration (CMC). This could effectively overcome the drawbacks of non-crosslinked micelles and show more attractive properties and better performance for biomedical applications. Furthermore, the characterization results and biological assays demonstrated that the final MPC-POSS-PhE FONs show stable aqueous stability, uniform size and morphology, high water dispersity, desirable optical properties and low cytotoxicity. These remarkable properties make the resultant AIE-active nanoprobes great potential for biomedical applications.
研究领域:
生物医学工程
·
材料科学
·
纳米技术
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2021
·
IF 8.742
Junhui Zhao,Xinda You,Guangzhe Wang,Jinqiu Yuan,Yafei Li,Chao Yang,Shiyu Zhang,Xiaoyao Wang,Runnan Zhang,Hong Wu,Zhongyi Jiang
Nanofiltration membranes that can selectively remove multivalent ions from salty water hold great promise in water treatment and salt utilization. However, developing nanofiltration membranes with high rejection to both divalent anions and cations remains a grand challenge. Herein, we design a kind of mix-charged polyamide membranes (MCPMs) via molecular hybridization to achieve the removal of versatile divalent ions. Amino-functionalized polyhedral oligomeric silsesquioxane (NH 2 -POSS) was employed as molecular filler added into piperazine and reacted with trimesoyl chloride at the aqueous-organic interface to generate cross-linked polyamide-NH 2 -POSS mixed network. The protonated amino groups from NH 2 -POSS offered positively charged sites for enhanced divalent cation repulsion while the deprotonated carboxyl groups from polyamide network can afford negatively charged sites for divalent anion repulsion. The optimized membrane displayed high rejections to both divalent anionic and cationic ions (Na 2 SO 4 rejection of 98.2%, MgCl 2 rejection of 98.0%), together with high mono-/divalent salt selectivity (NaCl/Na 2 SO 4 of 48.2, LiCl/MgCl 2 of 43.9) that outperformed the benchmark nanofiltration membranes. This molecularly-hybridized charge modulation method may enlighten the structural design of membranes for efficient ionic separations.
研究领域:
材料科学
·
环境工程
·
膜技术
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产品关联
DOI
高影响因子
INDUSTRIAL CROPS AND PRODUCTS
·
2024
·
IF 5.6
Shichao Xu,Xiaoyu Yang,Yanju Lu,Liang Yuan,Tianyu Zhu,Shuping Huo,Yuxiang Chen
Polybenzoxazines (PBozs) are regarded as prime candidates as low dielectric matrixes. However, the fabrication of high-performance PBozs that combines low dielectric property with high thermal stability using sustainable resources as the starting raw materials remains a significant challenge. In this work, we constructed a novel main-chain benzoxazine (Boz) oligomer from natural essential oil-derived compounds (eugenol and p -menthane diamine) to fulfill the principles of green chemistry. To enhance their low dielectric properties, polar C-Si unit on the main-chain and cellular structure of polyoctahedral silsesquioxanes (POSS) as the cross-linkers were introduced in PBoz-POSS composites. The obtained composites demonstrated excellent thermal stability, mechanical property, and with remarkable low dielectric constants . Coupled with their exceptional hydrophobicity and heat resistance, these materials are promising matrixes for low dielectric application in contemporary electronic industries.
研究领域:
材料科学
·
化学工程
·
电子工程
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产品关联
DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2020
·
IF 3.573
Peng Liang,Yuming Chen,Congjing Ren,Mei Chen,Binbo Jiang,Jingdai Wang,Yongrong Yang,Wei Li
Ultrahigh-molecular-weight polyethylene (UHMWPE) with a low polydispersity exhibits excellently physical and mechanical properties. In this work, a polyhedral oligomeric silsesquioxane (POSS)-modified Ziegler–Natta catalyst has been explored to synthesize the UHMWPE with a narrow molecular weight distribution. Diffuse reflection infrared spectroscopy combined with CO as the molecular probe, X-ray photoelectron spectroscopy, and diffuse reflectance UV–vis spectroscopy are employed to trace the evolution of the catalyst structure based on the investigation of vibrational and electronic properties of molecules. The results demonstrate that the chemically grafted POSS molecules are distributed evenly on the silica surface at the molecular level. The POSS can capture the MgTi compounds through protonation with the residual silanols, acting as a vertical support for active sites. The resulting active sites grafted on the POSS present much stronger Lewis acidity and were less heterogeneous (only tetra-coordinated Mg2+ species) in comparison to the active sites directly grafted or absorbed on the silica surface. This less heterogeneity of active sites enables to synthesize the UHMWPE with a much narrow distribution, reducing the molecular weight distribution from 6.7 to 3.9.
研究领域:
材料科学
·
聚合物化学
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DOI
高影响因子
Journal of Materials Chemistry A
·
2026
·
IF 9.2
Aoqing Yan,Guixiang Li,Yi Luo,Bing Han,Zhe Su,Hao Tian,Bo Niu,Donghui Long
Silica aerogels are widely regarded as promising candidates for high-performance thermal insulation, yet achieving a balanced combination of mechanical robustness and high-temperature stability remains a persistent challenge. In this work, we report a robust, thermally stable, and machinable silicone aerogel featuring a “rigid–flexible” integrated architecture, synthesized through the co-condensation of a POSS-based hyperbranched siloxane–amino/epoxy resin (POSS-SAE) with linear polymethylhydrosiloxane (PMS). Prepared via a temperature-controlled amine/epoxy addition–polycondensation process, the hyperbranched POSS-SAE incorporates a rigid POSS core, flexible long alkyl chains, and multiple reactive functional groups, achieving an intrinsic rigid–flexible molecular balance. Benefiting from this structural design, its copolymerization with long-chain PMS yields an aerogel with an ultrahigh-connectivity network, enabling a synergistic improvement in both mechanical strength and thermal performance. Consequently, the resulting POSS-PSA aerogel exhibits a compressive strength of 6.1 MPa, a low thermal conductivity of 0.036 W m−1 K−1 at room temperature, and an impressive char yield of 72.4% at 1000 °C under nitrogen. Furthermore, a low-density quartz fiber-reinforced composite (POSS-PSC) based on this aerogel matrix achieves a tensile strength of 27.8 MPa and delivers outstanding thermal insulation up to 1000 °C as well as excellent ablation resistance up to 1600 °C. Consequently, these exceptional properties make POSS-VPSC highly promising for demanding thermal protection applications, particularly in advanced aerospace thermal protection systems (TPSs), reusable launch vehicle insulation, and industrial thermal management.
✓ 已验证
DOI
高影响因子
POLYMER BULLETIN
·
2026
·Vol. 83
·期 11
·610
·
IF 4.2
Zhong Tian,Liu Wenlong,Dong Hangshuo,Tang Shaoguo,Ren Hongyu,Zhang Xingwen
Polyimide (PI) is widely used in the fields of integrated circuits and microelectronics due to its strong structure designability and excellent dielectric properties. However, the dielectric constant and loss of traditional PI are relatively high, which cannot meet the requirements of 5G development. In this work, a fluorine-containing photosensitive PI (PSPI) with excellent solubility was prepared by a two-step method. The reactive diluents and a photoinitiator were added to prepare a PSPI resin. After UV curing, the contact angle of the PSPI film was 67.4°, and the relative dielectric constant measured at 1000 kHz was 2.51. By adding 7-phenyl-epoxy polyhedral oligomeric silsesquioxane (B-POSS) as a modifier, at a B-POSS loading of 5%, the resultant POSS/PSPI composite film achieved the maximum contact angle of 94.5°, representing a 40.2% increase compared with pure PSPI. When the B-POSS content was elevated to 7%, the composite delivered the minimum relative dielectric constant of 2.04 at 1000 kHz, which was reduced by 18.7% relative to the pristine PSPI. The addition of B-POSS improved the hydrophobicity and dielectric properties of the PSPI film. This research provides a feasible approach for obtaining low dielectric PI films with excellent comprehensive performance in the field of electronic devices.
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DOI
高影响因子
REACTIVE & FUNCTIONAL POLYMERS
·
2020
·
IF 3.333
Xiaojing Zhang,Yang Meng,Weiwei Shen,Jingcheng Dou,Ruixue Liu,Qingxian Jin,Shaoming Fang
Injectable polysaccharide-based hydrogels are widely employed as drug delivery and tissue engineering materials due to the promising biocompatibility and biodegradability , while the mechanical property of polysaccharide hydrogels still requires to be enhanced much for further applications. In the present work, a family of injectable nanocomposite hydrogels were prepared for the first time through the Schiff base reaction between cationic octa (γ-chloroammoniumpropyl) silsesquioxane (OCAPS), chitosan (CS), and oxidized hydroxypropyl cellulose (HPC). It was found that OCAPS dispersed well in the hydrogels and inhibited the crystallization of CS and HPC, and the resulted nanocomposite hydrogels response pH values by reversible sol-gel transitions, namely as the pH value was less than 4.2, the hydrogels were low viscous solutions; while gelled again in mild and basic conditions. The gelation time of the hydrogels shrank from 80 to 49 s, and the swelling ratio increases from 3.7 to 6.6, along with the increase of OCAPS feed ratio gradually. The incorporation of OCAPS into the system also enhanced the mechanical property of the hydrogels. Compared with the controllable hydrogel without OCAPS, which failed to remain a certain shape for a long time, the nanocomposite hydrogels exhibited an outstanding compression property, and 68.4% of stain, 4.1 kPa of modulus, 97.9 kPa of strength when 40.0 wt% OCAPS was loaded. The rheological investigations suggested that the hydrogels possessed a very stable network, hence a self-healing property. Moreover, the result of Bovine serum albumin (BSA) load and release experiments demonstrated much improved drug load efficiency and cumulative drug release percentage of the nanocomposite hydrogels; the in-vitro degradation and cytotoxicity tests exhibited perfect biodegradability and biocompatibility of the hydrogels. All of these results demonstrate that the OCAPS and polysaccharides based hydrogels endow sound applications in drug carrier and tissue engineering materials.
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产品关联
DOI
高影响因子
POLYMER DEGRADATION AND STABILITY
·
2024
·
IF 6.3
Zeqi Zhang,Liang Qiao,Xue Bi,Keshan Zhang,Wenchao Zhang,Rongjie Yang
Vinyl ester resin (VER) are widely used in various applications, including automotive parts, yachts, wind turbine blades, and cooling towers, due to their excellent properties. However, the high flammability of VER limits its application in fields requiring stringent fire resistance. In this work, we used ionic liquid containing phospholipid structures (VIDHP) in combination with lithium-containing polyhedral oligomeric phenyl sesquisiloxanes (Li-POSS) to improve the mechanical and flame retardant properties of VER. The coordination between the VIDHP and Li-POSS increases the thermal stability of VIDHP and improve the solubility of Li-POSS in VER. The experimental results show an increase in initial decomposition temperature of VIDHP4/POSS1/VER compared to VIDHP/VER, while the solubility of Li-POSS in VER is improved. The Cone calorimeter results show that the total heat and smoke release of VIDHP4/POSS1/VER are reduced by 29.37 % and 36.55 % compared with the pure VER. The investigation of the flame retardant mechanism shows that the combined use of VIDHP and Li-POSS exhibits flame-retardant activity in both the gas and condensed phases, effectively enhancing the flame-retardant property of VER.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2022
·
IF 4.326
Tao Guo,Qi Zhou,Yuming Chen,Wei Li,Peng Liang,Jingdai Wang,Yongrong Yang
The preparation of ultra-high-molecular weight polyethylene (UHMWPE) with few entanglements and a fine particle size remains a significant problem for academia and industry. In this research, a novel MgCl2-based heterogeneous Ziegler–Natta catalyst modified with polyhedral oligomeric silsesquioxane (4-OH POSS) of fine particle size was successfully synthesized by screening solvents and Grignard reagents. Scanning electron microscopy, high-angle annular dark-field imaging, diffuse reflectance infrared spectroscopy, and X-ray photoemission spectroscopy tests were utilized to analyze the macroscopic morphology, microscopic composition, and active site distribution of the catalyst. Numerous POSS nanocrystals were stably embedded on the catalyst surface, and TiCl4 active sites are prone to immobilization on the POSS nanocrystals. However, TiCl4 loaded on the POSS nanocrystals exhibits nearly no activity, which acts as the isolator for separating the active sites loaded on the δ-MgCl2 surface. The isolation effect of POSS nanocrystals and the increased crystallization behavior of non-porous features for the catalyst collectively lead to the preparation of weakly entangled UHMWPE. The effects of sensitivity of cocatalyst reducibility, TiCl4 loading contents, and polymerization temperature on the catalytic activity and the UHMWPE performance were explored. Interestingly, the UHMWPE with less entanglements (initial elastic modulus = 0.23 MPa) and fine particle size (∼110 μm) was synthesized, exhibiting the overall reinforced strength/stiffness/toughness balance.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Gang Zhao,Peipei Xu,Gang Wei,Kezhen Zhang,Chunxue Yi,Shanyi Guang,Hongyao Xu
Intelligent materials are functional material systems with intelligent responses to external stimulation. With the continuous advances in science and technology, intelligent materials have surfaced as a research trend in material science and are providing a new direction for the systematic application of nanocomposite materials. In this study, an intelligent organic-inorganic nano-hybrid sensor or intelligent nanorobot, POSS-RHB-PEG, was developed by employing density functional theoretic calculations (DFT) under the Gaussian 03 program by a “Click Chemistry” based preparation strategy, in which RHB group can act as a recognizing ion in the cell under the action of intense coordination field and then as a function of coordinating ions. A low-chain PEG with good cell permeability functions as a machine wheel on account of the principle of osmotic pressure. The POSS-based nanorobotic molecular analytical device, with appropriate bio-compatibility, was designed and developed for the semiquantitative, intuitive, and sensitive detection and morphological analysis of Al 3+ ions in a real sample with a detection limit of 1.0×10 −8 M. Significant color evolutions from colorless to red were observed by the naked eye under the ultraviolet lamp, resulting in a semiquantitative visual detection. Compared to the organic sensing material RHB-Ac, the intelligent nanorobot POSS-RHB-PEG has high stability, selectivity (sulfhydryl group can self-screen Fe 3+ ions), and good biocompatibility. Furthermore, the nanohybrid nanorobot sensor successfully targeted HeLa cells, monitored cellular endogenous Al 3+ , and assessed cell stress in living cells. The nanohybrid nanorobot sensor POSS-RHB-PEG was also able to detect and image Al 3+ in living nude mice, indicating its exceptional detection potential in biological systems, it mainly involves the detection of metal ions in blood and the detection and treatment of heavy metal ions caused by clinical bone and joint replacement.
研究领域:
材料科学
·
生物医学工程
·
纳米技术
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产品关联
DOI
高影响因子
APPLIED ORGANOMETALLIC CHEMISTRY
·
2019
·Vol. 34
·期 1
·e5266
·
IF 3.259
Birong Zeng,Rong Hu,Ruirui Zhou,Hong Shen,Xinyu Liu,Guorong Chen,Yiting Xu,Conghui Yuan,Weiang Luo,Lizong Dai
A metal-doped organic and inorganic hybrid polyhedral oligomeric silsesquioxanes (POSS) with a titanium atom in the POSS cage and an ethanolamine substitute group in the corner, namely MEA-Ti-POSS, was synthesized through simple condensation reaction and substitute reaction. It was blended with 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO) to form a kind of blending-type flame retardant system for the modification of epoxy resins. The thermal stability, flame retardancy and mechanical properties of cured epoxy resin composites were studied. Comparing with pure epoxy resin, the LOI value of EP/MEA-Ti-POSS/DOPO composites was raised from 25.2% to 32.7%, and the UL-94 grade reached V-0 level at a loading of the mixture of 5% MEA-Ti-POSS and 5% DOPO. In addition, the cone calorimetry results showed that the heat release rate, total heat release and total smoke production as well as smoke production rate were all reduced during the combustion of EP/MEA-Ti-POSS/DOPO composites. The residual char analysis revealed that carbon residues of EP/MEA-Ti-POSS/DOPO composite served as a physical protective layer to insulate the oxygen and combustible gases to reduce the ablation of the matrix. It was concluded that the mixture of MEA-Ti-POSS and DOPO not only effectively raised the thermal stability and flame retardancy of epoxy composited materials, but also improved their mechanical properties, which expanded a promising application of the metal-POSS derivatives as non-halogen additives in the flame retardant polymers.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
DENTAL MATERIALS
·
2025
·
IF 6.3
Qingyang Zhou,Jiwei Lin,Qifang Li
Objectives The aim of this study was to develop a new composite resin to solve the problem of volume shrinkage of conventional dental restorative composite resins during the curing process in order to improve their mechanical properties and reduce the risk of restoration failure. Methods We synthesized the mercapto-alkenyl click chemical reaction product (MN-POSS) of acrylate-based POSS (MAP-POSS) with N-Acetylcysteine (NAC) using a bifunctional polysilsesquioxane modification technique and improved its dispersion in the resin matrix by physicochemical methods. In addition, methacrylate-based epoxy POSS (ME-POSS) was further synthesized and used to modify acrylate dental resins to form a free radical-cation hybrid light-curing system. Results The results showed that the composites modified with MN-POSS significantly improved mechanical strength, while the application of ME-POSS effectively reduced polymerization shrinkage, improved the water absorption and dissolution properties of the materials, and enhanced mechanical properties and hardness. This study provides new ideas and material solutions to improve the performance of dental restorative materials. Significance Both of these improved solutions demonstrate the potential of bifunctional POSS as a modified filler, providing new ideas and methods for the design of future dental restorative materials.
研究领域:
材料科学
·
牙医学
·
高分子化学
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）