CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Xin Tao,Jingyu Ren,Danjun Wang,Hua Huang,Yani Li,Di Guo,Baoqin Shan,Yu Liu,Jian Wang,Yanzhong Zhen,Zhirui Niu
The low activity of photocatalysts is mainly due to inefficient charge separation and low production of the active species. To overcome this challenge, we constructed an S-scheme CdIn 2 S 4 /MnZnFe 2 O 4 (CIS/MZFO) heterostructure, where the strong interface of the heterostructure leads to an upshift of the d-band center. CIS/MZFO shows higher charge transfer efficiency and oxygen adsorption/activation performance compared to CIS and MZFO separately, thereby increasing the production of ·O 2 − and h + active species. As a result, it demonstrats efficient photocatalytic degradation of tetracycline hydrochloride. The optimized CIS/MZFO heterostructure also shows good tolerance to various factors, such as inorganic ions, organic acids, pH and real water environments. The heterostructure also exhibits excellent magnetic recyclability and stability. Additionally, we propose a photocatalytic degradation pathway for tetracycline hydrochloride and evaluate the ecological toxicity that may arise from intermediates. This study provides an effective approach for the design of advanced photocatalysts.
研究领域:
材料科学
·
光催化
·
环境科学
✓ 已验证
DOI
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2016
·
IF 2.822
Fang Long,Jing Wang,Zhaohui Zhang,Liang Yan
A novel magnetic molecularly imprinted electrochemical sensor (MMIP-sensor) combined with magnetic molecularly imprinted solid-phase extraction (MMISPE) was constructed for rapid and sensitive detection of tetrabromobisphenol S (TBBPS) in water samples. The magnetic molecularly imprinted polymer based on magnetic graphene/multi-walled carbon nanotubes hybrid composite (MMIP/Gr-MWCNTs) was prepared as MMISPE sorbet to separate and enrich TBBPS from complex system. Adsorption results showed that the MMIP/Gr-MWCNTs possessed excellent selective adsorption toward TBBPS with a maximum adsorption capacity of 17.83 mg g − 1 . The magnetic imprinted sensor based on the magnetic Gr-MWCNTs composite modified electrode was prepared by electropolymerization of dopamine monomer . The high sensitivity of the MMIP-sensor was attributed to the large specific surface area and excellent electrical conductivity of the magnetic Gr-MWCNTs composites. The detection limit of the MIP-sensor toward TBBPS was calculated as 2.1 × 10 − 11 mol L − 1 (S/N = 3). Under the optimum conditions, the MISPE-MMIP-sensor combination system provided 10–12 fold preconcentration than that of MMIP-sensor alone determination. The MISPE-MMIP-sensor was successfully used for detection of TBBPS in drinking water , rain water , lake water and tap water with recoveries of 88.4–98.8%.
研究领域:
分析化学
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环境监测
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电化学传感
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分子印迹技术
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水处理
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污染物检测
✓ 已验证
DOI
高影响因子
Heliyon
·
2023
·Vol. 9
·期 7
·e18046
·
IF 4
Weijie Zhang,Lei Shi,Wei Zhou,Xin Liu,Yuan Xi,Xinyin Wang,Ya Li,Xia Xu,Youcai Tang
Breast cancer is one of the most common cancers. Oridonin, a traditional Chinese medicine, is believed to inhibit tumor growth, but its particular effects on breast cancer remain unknown. In this study, we examined oridonin's effects on 4T1, MCF-7, and MDAMB-231 cellular activity using CCK8. Scratch assays were used to detect oridonin's effects on cellular migration. Oridonin's effects on the breast cancer cell cycle were studied using flow cytometry, and expression of cell cycle related proteins p53, CDK2, and p21 was detected using Western blot assays. Metabolomics assays were used to detect changes in small molecule metabolites and metabolic pathways in breast cancer cells after treatment with oridonin. Oridonin's effects on breast cancer growth were also studied using xenograft mice. Metabolomics assays were used to detect changes in metabolites and metabolic pathways in xenograft mouse plasma in a control group, model group, and drug administration group. Experimental results showed that oridonin could significantly inhibit breast cancer growth both in vivo and in vitro. Scratch experiments showed that oridonin could inhibit breast cancer cell migration. Oridonin was also able to arrest cells in S phase by affecting several cell cycle-related proteins, including p53, CDK2, and p21. Metabolomic analysis of 4T1 cells identified a total of 33 differential metabolites, including multiple amino acids (such as l-Glutamic acid, l-Asparagine, l-Histidine, l-Valine, and l-Isoleucine). KEGG pathway enrichment analysis showed significant changes in aminoacyl-tRNA biosynthesis, and in multiple amino acid metabolic pathways. Plasma metabolomic analyses of xenograft mice revealed 28 differentially-expressed metabolites between the different animal model groups, including multiple amino acids. KEGG pathway analysis showed significant alterations in multiple amino acid metabolic pathways in oridonin-treated mice. Additionally, changes in the expression of PI3K, AKT and mTOR proteins, as well as in branched amino acids, suggest that oridonin affects the PI3K/AKT/mTOR signaling pathway by inhibiting the biosynthesis of valine, leucine and isoleucine. Taken together, our results suggest that oridonin has strong anti-tumor activity in vitro and in vivo, and has potential as an adjuvant to breast cancer treatment regimens.
研究领域:
肿瘤学
·
药理学
·
分子生物学
·
代谢组学
✓ 已验证
DOI
PubMed
高影响因子
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY
·
2022
·
IF 0.847
Ruiqi Gao,Huan He,Junxian Bai,Lei Hao,Rongchen Shen,Peng Zhang,Youji Li,Xin Li
ABSTRACT Nowadays, conjugated polymers have garnered numerous attention as a new class of organic photocatalysts due to their tunable electronic properties, low cost, excellent stability and sufficient light-absorption performance. In particular, pyrene-benzothiadiazole-based conjugated polymer (PBBP) has been considered to be a new type of conjugated polymers for photocatalytic H 2 evolution. However, the poor charge separation seriously limits its practical application in H 2 evolution. In this work, a PBBP-based polymer/CdS 2D/2D organic/inorganic S-scheme heterojunction photocatalyst with a strong internal electric field is, for the first time, prepared for efficient photocatalytic hydrogen evolution. The pyrene-benzothiadiazole-based conjugated polymers (PBBP) are synthesized by the Suzuki-Miyaura reactions. Then, the hybrid heterojunction photocatalysts are fabricated by coupling CdS with it through the ultrasonic mixing method. As a result, the highest H 2 -production rate of 15.83 mmol h −1 g −1 is achieved on 20% PBBP/CdS composite under visible-light irradiation, nearly 2.7 times higher than that of pure CdS. The apparent quantum efficiency (AQE) of 20% PBBP/CdS composite could reach 8.66% at λ = 420 nm. The enhanced activity could be attributed to the construction of S-scheme heterojunction, which accelerates the recombination of carriers with weaker redox ability and maintains the strong reducibility of electrons in CdS. This work provides a protocol for pyrene-benzothiadiazole-based conjugated polymers to prepare S-scheme heterojunction photocatalysts based on organic/inorganic coupling.
研究领域:
材料科学
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化学工程
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光化学
·
催化
✓ 已验证
DOI
高影响因子
International Journal of Minerals Metallurgy and Materials
·
2022
·Vol. 29
·期 5
·1120-1131
·
IF 3.85
Yan Wenjing,Zhang Jintao,Lü Aijing,Lu Songle,Zhong Yiwei,Wang Mingyong
Stable non-noble metal bifunctional electrocatalysts are one of the challenges to the fluctuating overall water splitting driven by renewable energy. Herein, a novel self-supporting hierarchically porous Ni x Fe—S/NiFe 2 O 4 heterostructure as bifunctional electrocatalyst was constructed based on porous Ni—Fe electrodeposition on three-dimensional (3D) carbon fiber cloth, in situ oxidation, and chemical sulfuration. Results showed that the Ni x Fe—S/NiFe 2 O 4 heterostructure with a large specific surface area exhibits good bifunctional activity and stability for both hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) because of the abundance of active sites, synergistic effect of the heterostructure, superhydrophilic surface, and stable, self-supporting structure. The results further confirmed that the Ni x Fe—S phase in the heterostructure is transformed into metal oxides/hydroxides and Ni 3 S 2 during OER. Compared with the commercial 20wt% Pt/C∥IrO 2 —Ta 2 O 5 electrolyzer, the self-supporting Ni 1/5 Fe—S/NiFe 2 O 4 ∥Ni 1/2 Fe—S/NiFe 2 O 4 electrolyzer exhibits better stability and lower cell voltage in the fluctuating current density range of 10–500 mA/cm 2 . Particularly, the cell voltage of Ni 1/5 Fe—S/NiFe 2 O 4 ∥Ni 1/2 Fe—S/NiFe 2 O 4 is only approximately 3.91 V at an industrial current density of 500 mA/cm 2 , which is lower than that of the 20wt% Pt/C∥IrO 2 —Ta 2 O 5 electrolyzer (i.e., approximately 4.79 V). This work provides a promising strategy to develop excellent bifunctional electrocatalysts for fluctuating overall water splitting.
研究领域:
材料科学
·
电化学
·
可再生能源
·
催化
✓ 已验证
DOI
高影响因子
ANALYTICA CHIMICA ACTA
·
2019
·
IF 5.256
Jun Yao,Min Chen,Nannan Li,Chaohui Liu,Mei Yang
As an ideal alternative to bisphenol A (BPA), bisphenol S (BPS) has similar biotoxicity, teratogenicity , carcinogenicity and mutagenicity as BPA. Nevertheless, to date, a fast, sensitive and portable method for meeting on-site measurement of BPS had not been established. Hence, it was particularly urged to develop a fast and highly sensitive method for tracing BPS. Currently, a novel molecularly imprinted polymer (MIP) electrochemical sensor had been successfully fabricated for the detection of BPS, wherein the composite of three-doped carbon quantum dots (B, N, F-CQDs) and silver nanoparticles (AgNPs) were utilized as an electron conducting layer, and MIP was applied as recognition element of target molecules. The step-by-step fabrication process and the adsorption capacity of the modified electrode were evaluated by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and chronocoulometry (CC). The results indicated that the synergy between B, N, F-CQDs and AgNPs dramatically improved the sensitivity of the electrode and achieved the amplification of the electrical signal. Meanwhile, the electrochemical activities of BPS were explored by CV and differential pulse voltammetry (DPV). And, the various parameters relating to the electrochemical kinetic properties of BPS were calculated. To the best of our knowledge, this was rarely reported in peer journals. The MIP remarkably improved the selectivity of the sensor owing to the specific recognition of the imprinted cavities. The linear response range of the new sensor was 1 × 10 −8 M to 5 × 10 −5 M with a detection limit of 1.12 × 10 −8 M and the electrode designed in this paper could meet the requirement of trace-level measurement of BPS in biological and environmental samples. Additionally, the sensor was used to determine BPS in plastic products with good anti-interference and acceptable recovery.
研究领域:
分析化学
·
环境科学
·
材料科学
✓ 已验证
DOI
PubMed
高影响因子
FUEL
·
2025
·
IF 7.5
Lina Dai,Qiang Li,Xianglan Dong,Enqi Zhang,Yufeng Hu,Xin Guo,Yanduo Liu
Photocatalysis exhibits great potential for applications in solving energy and environmental problems, and has received widespread attention. This article constructs a new type of Mn-Fe Prussian blue analogues S-scheme mechanism photocatalytic material. The material is composed of oxidized photocatalysts (Ag 2 MoO 4 ) and reduced photocatalysts (Mn-Fe PBAs). The composite photocatalyst constructed in this way shows advantages such as a wide spectral response range, high charge carrier separation efficiency, and strong oxidation–reduction ability, which can significantly enhance photocatalytic efficiency. By studying the construction method and CO 2 reduction performance of the photocatalyst, the structure-performance relationship can be clarified. The CO production rate is 43.3 μmol/g/h, and the selectivity can reach 94.9 %, which is far superior to the current mainstream photocatalytic system. The electron transfer kinetics and S-scheme charge separation mechanism between the Mn-Fe PBAs and Ag 2 MoO 4 interfaces are explained by steady-state surface photovoltage spectroscopy (SS-SPS) and near ambient pressure XPS (NAP-XPS). In-situ DRIFTS techniques are used to monitor the changes of transition intermediates, and combined with theoretical calculations, the activation mechanism of CO 2 by the Mn-Fe catalytic site is deeply revealed at the atomic level. This study provides new theoretical guidance and profound insights for the construction of Prussian blue analogues photocatalysts.
研究领域:
材料科学
·
环境科学
·
物理化学
·
纳米技术
·
催化
·
能量转换
✓ 已验证
产品关联
DOI
高影响因子
WASTE MANAGEMENT
·
2025
·
IF 7.1
Dongping Song,Tao Huang,Xiaolong Sun,Yun Xia,Chong Luo,Jialin Cui,Kai Chen,Weihua Liu,Jie Ren
The poor pozzolanic activity and high alkalinity of municipal solid waste incineration fly ashes (MSWI-FA) would deteriorate the stability of the MgO-SiO 2 -H 2 O (M−S−H) binder system, further inhibiting the treatment capacity of cement to wastes. In this study, sulfhydryl-functionalized graphene oxide nanoparticles (SFG) were synthesized and incorporated into the MSWI-FA-blended M−S−H (MSH-MSWI-FA) system to strengthen the solidification/stabilization (S/S) of both heavy metals (HMs) and chloride salts in the matrix and mechanical stability of cement. The linear increases in nanomaterials (from 0.5 % to 2.5 %) and MSH (from 40 % to 80 %) both decreased the concentrations of HMs and Cl anions leached from the solidified cubes in the MSH-MSWI-FA cementation. The least leaching concentration of Zn, Cu, Pb, Cd, Cr, and Cl were 0.0046 mg/L, 0.0032 mg/L, 0.014 mg/L, 0.00068 mg/L, 0.030 mg/L, and 0.36 g/L from the SFG-MSH-MSWI-FA cemented samples, respectively. The incorporation of graphene oxide nanoparticles (NGO) and SFG elevated the residual moieties of HMs, enhanced the mechanical strength and acid resistance, and improved the microstructural properties of MSH-MSWI-FA cementation. SFG played a more dominant role in the enhancement than NGO. Sulfhydryl-functionalization for nanomaterials intensifies the improvement process. The minerals including M−S−H, CaO-SiO 2 -H 2 O (C-S-H), and Phase-5 were formed in the MSH-MSWI-FA cement. Silica fume (SF), lightly burnt magnesia (CC-MgO), and MSWI-FA reacted with each other in a ternary system, which induced the self-alkali-activated cementation of C-S-H, M−S−H, and magnesium oxychloride (MOC) cement.
研究领域:
环境科学
·
材料科学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
·
2021
·Vol. 146
·期 6
·2445-2462
·
IF 4.626
Usman Muhammad,Yu Haojie,Wang Li,Titinchi Salam,Khan Amin,Naveed Kaleem-ur-Rehman,Nazir Ahsan,Elshaarani Tarig,Fahad Shah,Amin Bilal ul
Ferrocene (Fc)-based polymers have promising application in burning rate catalysts (BRCs) for solid composite propellants, and some of them have already been practically used. However, they have some drawbacks such as high migration during a long-time storage. Copolymers of poly(2-(methacryloyloxy) ethyl ferrocene carboxylate- co -glycidyl methacrylic acid)s (P(FHEMA -co- GMA)s) were synthesized to overcome the migration problem of Fc-based BRCs as well as to boost the burning rate (BR) of ammonium perchlorate (AP)-based propellants. The structures of the obtained P(FHEMA -co- GMA)s were confirmed by proton nuclear magnetic resonance ( 1 H NMR) and Fourier transform infrared (FT-IR) spectroscopy. Cyclic voltammetry (CV) method was used to study their electrochemical behavior, and the P(FHEMA -co- GMA)s showed redox behavior for the existence of the Fc units. Because of the formation of integrated network structures, the P(FHEMA -co- GMA)s have good anti-migration performances. The BR catalytic property of P(FHEMA -co- GMA)s were investigated by thermogravimetry (TG) and differential thermogravimetry (DTG). They showed competent catalytic effects on the thermal decomposition of AP.
研究领域:
材料科学
·
电化学
·
推进剂技术
✓ 已验证
DOI
高影响因子
EUROPEAN FOOD RESEARCH AND TECHNOLOGY
·
2020
·Vol. 246
·期 9
·1857-1865
·
IF 2.366
Yang Fanfan,Xu Long,Liu Xiang,Chen Chen,Dias Alberto C. P.,Zhang Xiaoying
Abstract Bisphenol S (BPS) is a major alternative to Bisphenol A (BPA) newly applied in food packing material and disrupts reproductive and developmental endpoints through endocrine pathways. This study aimed to develop a rapid, sensitive, and accurate chemiluminescence immunoassay (CLIA) for the detection of BPS in canned beverage. Anti-BPS monoclonal antibody (mAb) was generated by immunizing Balb/c mice with immunogen (BPS–BSA conjugation). CLIA assay conditions, including 3-[9-(((3-( N -succinimidyloxycarboxypropyl) [4-methxylphenyl] sulfonyl) amine) carboxyl]-10-acridiniumyl)-1-propanesulfonate inner salt (NSP-SA-NHS) labeling ratio (1:40), antigen concentration (1 μg mL −1 ) and antibody titer (1:8000; 125 ng mL −1 in PBS (0.01 M, pH 7.4)) were determined, respectively. The half inhibition concentration (IC 50 ), detection limit (IC 10 ), and working range of the CLIA in canned beverage were 0.04, 1.48, and 0.32–5 ng mL −1 , respectively. Cross-reactivity with other bisphenols (4,4′-thiodiphenol, Bisphenol F, 4,4′- dihydroxy benzophenone, Bisphenol A and Bisphenol B) was less than 0.56%, and the recovery rates of BPS in canned beverage ranged from 80 to 109.2% (intra-assay) and from 82 to 108.4% (inter-assay). The results of CLIA were compared with high-performance liquid chromatography–UV (HPLC–UV) analysis, showing a good correlation of 0.956. After proper sample pre-treatment, this method allows relatively large amounts of sample analysis in a limited time period (30 min). Thus, it was deemed suitable and efficient for routine screening of BPS in canned beverage. Graphic abstract
研究领域:
分析化学
·
环境科学
·
食品安全
·
免疫学
·
毒理学
✓ 已验证
DOI
高影响因子
SYNTHESIS-STUTTGART
·
2015
·Vol. 47
·期 23
·3751-3757
·
IF 2.689
Zhijie Li,Quan Wen,Lihong Zhou,Xingmei Deng,Qingle Zeng
The synthesis of highly important α-hydroxycarboxylic acid anilides via copper-catalyzed chemoselective C–N coupling reactions of α-hydroxyamides and aryl halides is described. This highly selective N-arylation process demonstrates wide substrate scope, cost savings and easy operation. In addition, the chirality of l-3-phenyllactamide is preserved during the reaction.
研究领域:
有机化学
·
合成化学
✓ 已验证
DOI
高影响因子
SYNTHESIS-STUTTGART
·
2019
·Vol. 52
·期 02
·297-303
·
IF 2.867
Yi Zhang,Dongheng Zhou,Yongmin Ma,Jing Chen
A simple and efficient procedure for the synthesis of N-[(methylthio)methyl]benzamides and methylene-bridged unsymmetrical bisamides was achieved mediated by DMSO in the presence of acetic acid. DMSO plays a dual role in the transformation, as not only a solvent, but also an environmentally benign methylene source. The protocol provides new strategies for effective synthesis of unsymmetrical bisamides and avoids the use of transition-metal catalysts.
研究领域:
有机化学
·
绿色化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）