CHEMICAL ENGINEERING JOURNAL
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2015
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IF 4.321
Ziwei Zhang,Fang Wang,Weiben Yang,Zhen Yang,Aimin Li
In this study, a novel macroporous amination resin (named as GMDA) with the matrix of divinylbenzene and glycidyl methacrylate was synthesized and utilized to remove 8-amino-1-naphthol-3,6-disulfonic acid (H-acid) from water. The adsorption behaviors of the synthetic resin were studied systematically and compared with three commercial resins (the hypercrosslinked resin NDA-88, the anion-exchange resin D-301, and the macroporous resin XAD-4) in terms of adsorption capacity, equilibrium time, isotherm adsorption , the effect of existing inorganic ions and regeneration properties. The characteristic methods of BET surface area, pore size distribution, SEM , FTIR , XPS and Zeta potential were investigated to analyze the resins and adsorption process . The GMDA resin has wider pore diameter than the NDA-88 resin to attract H-acid more quickly with higher adsorption amounts; the larger BET surface area of the GMDA resin ensures more binding sites than the D-301 resin in the adsorption process; the functional groups on the surface of the GMDA resin is more effective than the hydrophobic matrix of the resin XAD-4 in the removal of H-acid. Especially, the regeneration and dynamic experiments indicate the anti-fouling performance of GMDA resin is much better than the others. This research not only provides guidance for understanding the adsorption mechanism of H-acid onto the four resins, but also gives theoretical basis for the design of resin structure according to the targeted contaminants.
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JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
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2015
·Vol. 122
·期 1
·349-358
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IF 2.042
Yu Guo-Min,Wang Li-Sheng,Sun Jian,Shao Xian-Zhao
A phosphorous flame retardant of phosphoric acid, P, P′-1, 4-phenylene P, P, P′, P′-tetraphenyl ester (PAPTE) was synthesized by diphenyl chlorophosphate and hydroquinone. The structural features of PAPTE were investigated with mass spectrometry, infrared spectroscopy, X-ray powder diffraction and nuclear magnetic resonance methods. The thermal behavior of PAPTE was carried out with thermogravimetric (TG) analysis instruments. The kinetic parameters, including the activation energy and pre-exponential factor of the decomposition process for the title compound, were calculated through the Friedman method, the Kissinger–Akahira–Sunose method and the Flynn–Wall–Ozawa method, while the thermal decomposition mechanism was also studied with the invariant kinetic parameters (IKP) method based on a set of TG data obtained at different heating rates. It was shown that the activation energies calculated for the decomposition reaction by different methods were found to be consistent with the conversion functions calculated by means of the IKP method which depend on a set of kinetic methods.
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BIOORGANIC & MEDICINAL CHEMISTRY
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2013
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IF 2.903
Xiu Liu,Ling Zhang,Jin-Guo Tan,Han-Hong Xu
Based on the discovery of thymine as an ecdysteroid agonist, a series of 1,4-disubstituted diacylhydrazine derivatives with a thymine moiety were designed and synthesized. The activities of these compounds against Spodoptera litura (Fabricius) were evaluated by the insect immersion method. Results showed that compound 2h with an N -cyclohexylmethyl substituent exhibits the most potent agonist activity with a median lethal concentration of 23.21 μg/mL. This compound also caused malformation of molting larvae and adults. Compound 2h was further demonstrated as an ecdysteroid agonist by reporter gene assay on the Spodoptera frugiperda cell line (Sf9 cells). A molecular docking study indicated that hydrophobic interactions and the formation of hydrogen bonds between the compounds and the ecdysone receptor play critical roles in promoting the binding affinity of the compound. The structure of compound 2h may serve as a favorable template for the development of new ecdysteroid agonists with a pyrimidinedione moiety.
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Journal of Nanomaterials
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2014
·
IF 1.611
Shifeng Li,Yanming Shen,Min Xiao,Dongbin Liu,Lihui Fan,Zhigang Zhang
Controlled release formulations have been shown to have potential in overcoming the drawbacks of conventional plant growth regulators formulations. A controlled-release formulation of 1-naphthylacetic acid (NAA) and indole-3-butyric acid (IBA) simultaneous intercalated MgAl-layered double hydroxides (LDHs) was prepared. The synthetic nanohybrid material was characterized by various techniques, and release kinetics was studied. NAA and IBA anions located in the gallery of MgAl-LDHs with bilayer arrangement, and the nanohybrids particles were of typical plate-like shape with the lateral size of 50–100 nm. The results revealed that NAA and IBA have been intercalated into the interlayer spaces of MgAl-LDHs. The release of NAA and IBA fits pseudo-second-order model and is dependent on temperature, pH value, and release medium. The nanohybrids of NAA and IBA simultaneously intercalated in LDHs possessed good controlled release properties.
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RSC Advances
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2015
·Vol. 5
·期 30
·23981-23989
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IF 3.84
Wei Xu,Chao Lin,Huan Liu,Hongbo Yu,Kai Tao,Shenghu Zhou
Tungsten substituted mesoporous FDU-12 (W-FDU-12) catalysts were synthesized by a one-pot hydrothermal process using F127 as the structure directing agent. The studies of TEM, SAXS and BET illustrated that the highly ordered mesoporous structure of FDU-12 was maintained in the doped W-FDU-12 samples. XPS studies revealed that a high concentration of W5+ species appeared in doped W-FDU-12 catalysts whereas supported WO3/FDU-12 and WO3/SiO2 catalysts only contained W6+ species. Tandem catalytic conversion of 1-butene and ethene to propene through isomerization of 1-butene to 2-butene and consecutive cross metathesis of 2-butene and ethene in a fixed-bed reactor at different temperatures and atmospheric pressure was used to evaluate the catalytic performance of the W-FDU-12 catalyst, combined with MgO. The catalytic results showed that the doped W-FDU-12 illustrated a superior catalytic performance relative to the supported WO3/FDU-12 and WO3/SiO2 catalysts. The higher metathesis activity of W-FDU-12 catalysts can be ascribed to the good dispersion of W species and the incorporation of W species into the framework of FDU-12, forming a substantial amount of W5+, which was beneficial for the cross metathesis of 2-butene and ethene to propene.
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JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
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2014
·Vol. 53
·期 6
·737-744
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IF 3.245
Ying-Ying Zhang,Ren-Jian Wei,Xing-Hong Zhang,Bin-Yang Du,Zhi-Qiang Fan
The alternating copolymerization of CO 2 with the terminated epoxides anchoring long alkyl groups is rarely reported because of their low reactivity and polycarbonate selectivity. This work describes a well-controlled solvent-free copolymerization of CO 2 with 1, 2-epoxydodecane (EDD) with a long electron-donating alkyl group via the catalysis of Zn-Co(III) double metal cyanide complex catalyst. The productivity of the catalyst was up to 2406 g polymer/g Zn, that is, EDD conversion was 99.2%. The alternating degree of CO 2 -EDD copolymers were more than 99% and had high number-average molecular weights ( M n s) of >100 kg mol −1 , while only 1.0 wt % 4-decyl-1,3-dioxolan-2-one (DC) were detected. Moreover, by introducing styrene oxide (SO) with electron-withdrawing phenyl group into EDD-CO 2 copolymerization system, a new random terpolymer with either electron-withdrawing or electron-donating side groups was produced with single glass transition temperatures ( T g s) in a wide range from 3 to 56 °C, which might be potentially used as biodegradable elastomers or plastics. © 2014 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2015 , 53 , 737–744
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TALANTA
·
2024
·
IF 5.6
Rui Liu,Chaojun Zhang,Tianheng Wu,Rijia Liu,Yuan Sun,Jing Ma
In this work, a novel HKUST-1/CoFe 2 O 4 /g-C 3 N 4 electrode was successfully prepared via the hydrothermal method and the high-temperature calcination method, which can be applied as an electrochemical sensor for the precise detection of ciprofloxacin (CIP) in physiological samples. The novel electrode was characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD) and Fourier-transform infrared spectroscopy (FT-IR), and its electrochemical performance was further evaluated via the cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques. The results demonstrated that the HKUST-1/CoFe 2 O 4 /g-C 3 N 4 electrode exhibited an optimal linear range of 0.05–180 μmol L −1 for the CIP detection, which demonstrated a low limit of detection (LOD) of 0.0026 μmol L −1 and a low limit of quantitation (LOQ) of 0.0087 μmol L −1 , respectively. Additionally, the novel semiconductor sensors exhibited exceptional selectivity, stability and repeatability in the determination of CIP. The recovery rate of CIP was found to range from 98.00% to 104.00% in serum, with the relative standard deviations (RSD) below 2.62% (n = 5), while the recovery rate of CIP was found to range from 96.00% to 105.00%, with the RSD less than 3.23% (n = 5) in urine. The current study extends to the application of the semiconductor-based electrochemical sensors and offers a new approach for the clinical pharmaceutical analysis to ensure medication safety, which could provide valuable insights into the potential of semiconductor sensors for future clinical applications.
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RSC Advances
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2024
·Vol. 14
·期 30
·21307-21317
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IF 3.9
Tian Xie,Han Qu,Chao Zhang,Zheng Li
Lithium extraction from salt lake brine is still challenging due to the existence of similar elements, e.g. sodium. In the present work, polysulfone (PSF) microcapsules containing 1-phenylazo-2-naphthol (HS) and trioctylphosphine oxide (TOPO) as extractants were successfully prepared by microfluidic technology for the separation of Li+ from brine with Li+ and Na+. The morphology, composition, and structure of HS-TOPO-based microcapsules were characterized systematically. The results showed that microcapsules consisting of 20 wt% (m m−1) polysulfone and 80 wt% (m m−1) 1-phenylazo-2-naphthol-trioctylphosphine oxide as the extractant, which was labeled as PSF/HS-TOPO-2/8, exhibited the best performance for Li+ adsorption. The separation factor (SF) of Li+ over Na+ is up to 653 and the adsorption capacity for Li+ in the simulated brine could reach 3.67 mg g−1 for microcapsules PSF/HS-TOPO-2/8, which demonstrated that Li+ can be separated with high selectivity. Besides, the kinetic results demonstrated that the adsorption followed quasi-secondary adsorption kinetic models, indicating that the adsorption mechanism of lithium by microcapsules involved chemisorption. After ten cycles of adsorption–elution, the maximum equilibrium adsorption capacity still remained at 87%. All these results demonstrate that PSF/HS-TOPO-2/8 microcapsules can be used as an efficient adsorber for the adsorption of Li+ from brine with high selectivity and stability.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2024
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IF 5.8
Xiaohui Zhang,Xinyue Zhong,Xiaohua Zhang,Yu Liu,Shuai Ma,Chenglong Yu,Zhenxing Yue
Dielectric ceramics in the microwave band are one of the crucial materials for mobile communication technology, and the studying of their phase evolution and defect behavior can help to understand and reduce dielectric loss. In this work, (1- x )BaNd 1.76 Bi 0.24 Ti 5 O 14 - x Ba 0.6 Sr 0.4 La 4 Ti 4 O 15 ( x = 0.2, 0.4, 0.6 and 0.8, (1- x )BNT- x BSLT) ceramics were synthesized by solid-state reaction method. X-ray diffraction (XRD) and Raman spectra analysis reveal that tungsten bronze and hexagonal perovskite phases coexist in the ceramics, and BaNd 2 Ti 3 O 10 is indexed as the main crystalline phase at x = 0.4, 0.6, leading to a deterioration of the microwave dielectric properties. The defect-related relaxation behavior and its effect on microwave dielectric properties were analyzed by dielectric temperature spectrum and thermally stimulated depolarization current (TSDC). The relationship between the dielectric constant and the electric field distribution was solved using the eigenmode of the high frequency structure simulator. In short, the (1- x )BNT- x BSLT ceramics at x = 0.8 exhibit excellent microwave dielectric properties: ε r = 47.2, Q × f = 16,800 GHz, and τ f = −4.6 ppm/°C. The microwave dielectric response of BNT-BSLT composite ceramics is closely related to the phase composition and defects, which is informative for the development of low dielectric loss ceramics.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Yijun Tu,Yijie Cai,Jiachuan Lei,Jianqing Yu
The programmed death-ligand 1 (PD-L1) protein plays a key role in immune responses. Scutellarin (SCU), as a flavonoid, has a variety of bioactivities. In this study, the human PD-L1 was obtained by expression and purification, and the interaction mechanisms between PD-L1 and SCU were revealed through multi-spectroscopy and computer simulation. Fluorescence data indicated that the quenching of PD-L1 by SCU was mainly static quenching, and primarily driven by hydrogen bonding and van der Waals forces. The binding constant (K a ) was decreased from 2.05 ± 0.55 × 10 4 L·mol −1 to 0.28 ± 0.08 × 10 4 L·mol −1 with increasing temperature. Meanwhile, the changes in the microenvironment of PD-L1 were revealed by the synchronous and the 3D fluorescence data. In addition, the melting temperature of PD-L1 increased by 1.67 °C after binding with SCU. Moreover, the circular dichroism data showed that SCU changed the secondary structure of PD-L1 by increasing α-helix content and decreasing β-sheet content. Furthermore, the binding modes between SCU and PD-L1 and the key residues involved in the interaction were revealed by molecular docking and molecular dynamics. These findings supported SCU as an alternative ICB therapeutic strategy and provided evidence for computer-based drug design strategies.
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ENVIRONMENTAL TOXICOLOGY
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2024
·
IF 4.4
Hong Wang,Jianmin Sang,Zhongyao Ji,Yang Yu,Shaowei Wang,Yang Zhu,Huitao Li,Yiyan Wang,Ren-shan Ge
Chlorinated bisphenol A (BPA) derivatives are formed during chlorination process of drinking water, whereas bisphenol S (BPS) and brominated BPA and BPS (TBBPA and TBBPS) were synthesized for many industrial uses such as fire retardants. However, the effect of halogenated BPA and BPS derivatives on glucocorticoid metabolizing enzyme 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) remains unclear. The inhibitory effects of 6 BPA derivatives in the inhibition of human and rat 11β-HSD1 were investigated. The potencies for inhibition on human 11β-HSD1 were TBBPA (IC 50 , 3.87 μM) = monochloro BPA (MCBPA, 4.08 μM) = trichloro BPA (TrCBPA, 4.41 μM) > tetrachloro BPA (TCBPA, 9.75 μM) > TBBPS (>100 μM) = BPS (>100 μM), and those for rat 11β-HSD1 were TrCBPA (IC 50 , 2.76 μM) = MCBPA (3.75 μM) > TBBPA (39.58 μM) > TCBPA = TBBPS = BPS. All these BPA derivatives are mixed/competitive inhibitors of both human and rat enzymes. Molecular docking studies predict that MCBPA, TrCBPA, TCBPA, and TBBPA all bind to the active site of human 11β-HSD1, forming hydrogen bonds with catalytic residue Ser170 except TCBPA. Regression of the lowest binding energy with IC 50 values revealed a significant inverse linear regression. In conclusion, halogenated BPA derivatives are mostly potent inhibitors of human and rat 11β-HSD1, and there is structure-dependent inhibition.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Xin Li,Kun Xu,Yiyang Bi,Dongjie He,Xin Wang,Ke Li,Qun Liu,Yu Zhang
A new HKUST-1@covalently crosslinked agarose aerogel (HKUST-1@CCAGA) was synthesized for the highly effective elimination of Methylene Blue (MB). Firstly, the covalently crosslinked agarose aerogel (CCAGA) was obtained by hydrothermal crosslinking reaction with epichlorohydrin (ECH) as crosslinker, which remained stabilized under hydrothermal and solvothermal conditions. Then, HKUST-1 was made to bind to CCAGA by in situ solvothermal assays, and the HKUST-1 loading rate reached 47.4 % based on thermogravimetric data and calculated using the cross over method. Meanwhile, the SEM exhibited the complete 3D honeycomb structure of CCAGA, and HKUST-1 particles uniformly distributed on its layers. Additionally, the specific surface area of HKUST-1@CCAGA can reached 648.59 m 2 ·g −1 . The HKUST-1@CCAGA composite was utilized for MB removal, achieving a high adsorption capacity of 424.30 mg·g −1 at pH 8. The adsorption of MB was also maintained at 80 % after 5 cycles of the experiment. The composite aerogel exhibits good recyclability and has excellent adsorption capacity.
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