RSC Advances
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2021
·Vol. 11
·期 34
·21084-21096
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IF 3.361
Tingting Chen,Shan Hu,Quanfeng Xing,Xiaofeng Yu,Jinming Chen,Xiaolong Li,Xiuquan Xu,Bo Zhang
Embedding heterocycles into the skeleton of g-C3N4 has been proved to be a simple and efficient strategy for improving light response and the separation of photo-excited charges. Herein, 2-thiobarbituric acid incorporated g-C3N4 (TBA/CN) with good photocatalytic efficiency for Rh B degradation and H2 production was successfully achieved via a facile thermal copolymerization approach. The incorporation of aromatics and S atoms into the skeleton of g-C3N4 was identified via systematic characterizations. This unique structure contributed to the narrowed band-gap, extended delocalization of lone pair electrons and changed electron transition pathway, which led to the enhanced visible light utilization, accelerated charge migration and prolonged electron lifetime, subsequently resulting in the significant boost of photocatalytic activity. The optimal TBA/CN-3 sample yielded the largest Rh B degradation rate constant k value of 0.0273 min−1 and simultaneously highest rate of H2 evolution of 0.438 mmol g−1 h−1, which were almost 3.5 and 3.8 folds as fast as that of the pristine CN, respectively. Finally, the photocatalytic mechanism was proposed for the detailed elucidation of the process of Rh B degradation coupled with H2 production.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2021
·
IF 5.316
Ziqian Lv,Hanyu Xu,Zhiying Wang,Mochen Jia,Yanling Wei,Zuoling Fu
The composite of biocompatible carbon dots (CDs) and lanthanide-based luminescent materials have high research value as a promising multifunctional material, which are ideally suited to information encryption and white LED. However, the aggregation-induced quenching of CDs in the solid state still troubles the synthesis of CDs with other solid luminescent materials. Herein, a facile strategy to fabricate polychromatic nanoplatform KLa(MoO 4 ) 2 : Eu 3+ @CDs by encapsulating CDs on the surface of KLM: Eu 3+ with silicon shell is reported, in which the aggregation-induced quenching of CDs is avoided. Due to the overlapping of Eu-O charge transfer band with CDs excitation band, the red luminescence of Eu 3+ ions and the blue fluorescence of can be emitted simultaneously under 395 nm excitation. By changing the proportion of KLa(MoO 4 ) 2 : Eu 3+ in KLa(MoO 4 ) 2 : Eu 3+ @CDs, the mixture can emit "warm", "neutral", and "cold" white light, which can realize people's demand for indoor lighting requirements. Furthermore, a multi-mode information encryption by selectively triggering the luminescence of CDs or Eu 3+ ions is also designed. All the results suggest that KLa(MoO 4 ) 2 : Eu 3+ @CDs have excellent luminescence properties that can be further investigated and applied in the field of white LEDs and information encryption.
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EUROPEAN JOURNAL OF PHARMACOLOGY
·
2021
·
IF 4.432
Yao Hua,Limei Zhou,Weidong Yang,Wenji An,Xiaolin Kou,Jian Ren,Hailang Su,Rong Chen,Zhengping Zhang,Jianjun Zou,Zhihong Zhao
Intracerebral hemorrhage (ICH) is a devastating disease, and there is currently no specific pharmacological treatment that can improve clinical outcomes. Y-2 sublingual tablets, each containing 30 mg edaravone and 6 mg (+) - borneol , is undergoing a phase III clinical trial for treatment of ischemic stroke in China. The purpose of the present study is to investigate the efficacy and potential mechanism of Y-2 in a rat model of collagenase IV injection induced ICH. Sublingual administration of Y-2 at the dose of 1, 3 and 6 mg/kg improved ICH-induced sensorimotor dysfunction, alleviated cell death and histopathological change, restored the hippocampal long-term potentiation (LTP), reduced brain edema and maintained blood-brain barrier (BBB) integrality in ICH rats. Further study demonstrated that Y-2 could reduce inflammatory response and oxidative stress by decreasing the levels of myeloperoxidase (MPO), ionized calcium-binding adaptor protein-1 (Iba-1), inflammatory cytokines and oxidative products, inhibit transcription factor nuclear factor-κB (NF-κB) activation, cyclooxygenase-2 (COX-2) and matrix metallopeptidase 9 (MMP-9) expression in brain tissue around in the core regions of hematoma . Importantly, the protective efficacy of Y-2 from ICH-induced injury was superior to edaravone. In conclusion, Y-2 sublingual tablets might be a promising therapeutic agent for the treatment of ICH.
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CHEMOSPHERE
·
2019
·
IF 5.108
Jian Lu,Qi Sun,Jun Wu,Guangcan Zhu
Techniques for reutilization of the discarded bischofite are limited while efficient recovery of the Mg(OH) 2 nanoparticles from water during the synthesis and reuse processes is a challenge. In this study, the Fe 3 O 4 @Mg(OH) 2 core-shell magnetic nanoparticles were firstly prepared from discarded bischofite and used as catalyst for improving the ozonation of metronidazole (MNZ). The removal rate constant of MNZ increased by 694.7% using Fe 3 O 4 @Mg(OH) 2 . Compared with the Mg(OH) 2 control, the MNZ removal rate constant of Fe 3 O 4 @Mg(OH) 2 treatment was almost tripled. The persistent high catalytic activity of the Fe 3 O 4 @Mg(OH) 2 catalyst was observed since the MNZ removal rate constant decreased by just 13.2% in the third reuse run. The Fe 3 O 4 @Mg(OH) 2 primarily enhanced ozone decomposition through producing hydroxyl radicals . The MNZ removal rate constant increased from 0.075 min −1 to 0.643 min −1 as catalyst dose increased from 0 to 0.6 g L −1 while it decreased by 96.0% when its initial concentration increased from 10 to 200 mg L −1 . The maximum removal rate constant was observed at 25 °C when temperature increased from 15 °C to 35 °C. The Cl − , HCO 3 − , SO 4 2− , Ca 2+ , Mg 2+ ions could jeopardize MNZ degradation. The antibacterial activity of MNZ was eliminated after catalytic ozonation while the mineralization efficiency was almost doubled. The nitro group reduction and the cleavage of hydroxyethyl bond were two main transformation pathways of MNZ. These findings suggest that Fe 3 O 4 @Mg(OH) 2 nanoparticle made from discarded bischofite is the promising catalyst for the ozonation of antibiotics in the terms of water purification practice and reutilization of the bischofite.
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Advances in Materials Science and Engineering
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2019
·
IF 1.399
Zhuo Yao,Dianli Qu,Yuxiang Guo,Yujing Yang,Hong Huang
Novel catalysts with high activity for the selective catalytic reduction of NO with NH3 (NH3-SCR) at low temperatures are highly demanded. In this study, mixed-node metal-organic frameworks (MOFs), e.g. Mn@CuBTC with controlled Mn composition in Cu3(BTC)2, were fabricated using postsynthetic exchange method and their structural characteristics and catalytic performances for NH3-SCR reaction were assessed. A series of analyses in terms of structure, surface morphology, texture, and chemical state determined that Mn ions were successfully incorporated into the Cu3(BTC)2 crystal lattice as well as adsorbed on the walls of nanopores in the framework. The pore sizes can be finely tuned in the presence of Mn ions in the cages, which significantly suppressed water adsorption. The NH3-SCR activity of Mn@CuBTC exhibited nearly 100% NOx conversion rate in the temperature range (230–260°C). The superior NH3-SCR performance is attributed to the proper pore sizes, reduced water content, and the synergistic effect between manganese and copper ions in the MOF structure, which enhanced NH3 bound to the active Lewis sites.
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JOURNAL OF POWER SOURCES
·
2019
·
IF 7.467
Jie Li,Lin Zhang,Furong Qin,Bo Hong,Qian Xiang,Kai Zhang,Jing Fang,Yanqing Lai
Lithium sulfur battery is deemed to one of the most hopefully useable and cost-effective options beyond traditional lithium ion batteries . Nevertheless, the intermediates shuttle effect and the instability of the lithium metal anode are still the significance of barriers to the actual application of lithium sulfur battery. In this work, zirconium oxynitrate (ZrO(NO 3 ) 2 ), which delivers good thermal stability and little hygroscopicity , is proposed as a dual functional electrolyte additive to ameliorate the electrochemical performance of lithium sulfur batteries. For one thing, the ZrO 2+ cations possess a strong affinity to sulfur, which can catalyze the conversion of dissolved polysulfides to S 8 . For another, ZrO(NO 3 ) 2 is negatively charged in the ether electrolyte because of the coordination ability of ZrO 2+ . It displays a strong repulsion to polysulfides which would effectively trap the dissolved polysulfides and prevent the polysulfides from diffusing into the electrolyte phase. Additionally, NO 3 − anions can be reduced and form a stable passivation film on Li-metal anode, which is beneficial to decrease the reacting activity of Li-metal anode upon polysulfides and stabilizing the surface topography of the Li-metal anode. Ultimately, the ZrO(NO 3 ) 2 electrolyte additive observably enhances the discharge capacity and cycle stability of Lithium sulfur battery.
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Catalysis Science & Technology
·
2019
·Vol. 10
·期 1
·263-267
·
IF 5.726
Gang Yuan,Yujie Hu,Zihan Wang,Qiwei Wang,Li Wang,Xiangwen Zhang,Qingfa Wang
Water oxidation plays a pivotal role in energy conversion and storage such as in water splitting and metal-air batteries. The development of a highly active and stable electrode for water oxidation at a low price is greatly challenging. Here, we report a self-supported oxygen evolution reaction (OER) electrode with a 3D porous Ni foam (NF) as a core and a dense layer of amorphous phosphorus-doped Ni hydroxide (Ni–OH/P) film as a shell. This facilely fabricated 3D core–shell structured electrode with directly grown active materials offered improved activity and prolonged stability for OER. It required an overpotential of 490 mV to deliver a current density of 100 mA cm−2; it showed a small Tafel slope at 87 mV dec−1 and sustained elongated electrolysis at 100 mA cm−2 for 100 h. The NiOOH shell was in situ formed on the surface of the Ni–OH/P film. Then, a new core–shell structured film was constructed. The synergetic effects of the newly formed crystalline NiOOH shell and amorphous Ni–OH/P core contributed to high stability under harsh conditions. This work presents a facile and easy scale-up path to develop self-supported hybrid electrodes for efficient and stable energy conversion and storage.
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CHEMICAL ENGINEERING JOURNAL
·
2019
·
IF 8.355
Tao Luo,Yanan Yuan,Danna Zhou,Liting Luo,Jinjun Li,Feng Wu
In the recent years, sulfite-induced oxidation of various contaminants using oxysulfur radicals (SO 4 − , SO 5 − and SO 3 − ) has been explored to establish novel advanced oxidation processes (AOPs). Although transition metals, such as cupric ions (Cu(II)), have been demonstrated to be capable of activating sulfite (S(IV)), the catalytic mechanism of the specific Cu(II) species is still not very clear. In this work, N-acetyl- para -aminophenol (APAP) was used as a basic substrate to investigate the process, mechanism and stability of the Cu(II)-S(IV) system with low dosages of Cu(II) (0.010 mmol L −1 ) in an alkaline solution (pH 10). The results show that 0.010 mmol L −1 Cu(II) can efficiently activate S(IV) for the oxidation of APAP and other contaminants (e.g., metoprolol, sulfanilamide, aniline, 4-chloroaniline, N,N-dimethylaniline, p -nitrophenol and 3-nitrophenol). Simulation calculations for the distribution of the Cu(II) species and pH-dependence of APAP oxidation in the Cu(II)-S(IV) system showed that Cu(OH) 2 particles are the major active species in the catalysis of S(IV). The surface complexation of S(IV) with the Cu(OH) 2 particles prior to the production of oxysulfur radicals is the basic mechanism of the alkaline Cu(II)-S(IV) system. Radical inhibition with scavengers (ethanol, tert-butyl alcohol or aniline) demonstrates that SO 5 − , SO 4 − and hydroxyl radicals (HO ) are responsible for the contaminant oxidation. Moreover, SO 5 − is believed to be the main active species in the Cu(II)-S(IV) system, which has a second-order rate constant of 2.98 × 10 8 M −1 s −1 with APAP. This work renews our recognition of the Cu(II)-S(IV) system applications and further understanding of the catalytic role of the nascent Cu(OH) 2 particles in the activation of S(IV).
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ENVIRONMENTAL TOXICOLOGY
·
2019
·Vol. 34
·期 5
·666-673
·
IF 2.649
Xia Wang,Chenqian Zhou,Bingnan He,Baida Kong,Lai Wei,Rong Wang,Jiajia Lin,Yiyan Shao,Jianbo Zhu,Yuanxiang Jin,Zhengwei Fu
Fluorotelomer alcohols (FTOHs) are fluorinated intermediates used in manufacturing specialty polymer and surfactants, with 8:2 FTOH the homologue of largest production. FTOHs were found to pose acute toxicity, hepatotoxicity, nephrotoxicity, developmental toxicity and endocrine-disrupting risks, whereas research regarding immunotoxicity and its underlying mechanism, especially on specific immune cells is limited. Here, we investigated the immunotoxicity of 8:2 FTOH on immature immune cells in an in vitro system. We observed that exposure of HL-60 cells, a human promyelocytic leukemic cell line, to 8:2 FTOH reduced cell viability in a dose- and time-dependent manner. In addition, 8:2 FTOH exposure caused G1 cell cycle arrest in HL-60 cells, while it showed no effect on apoptosis. Exposure to 8:2 FTOH inhibited the mRNA expression of cell cycle-related genes, including CCNA1 , CCNA2 , CCND1 , and CCNE2 . Moreover, exposure to 8:2 FTOH inhibited the mRNA expression of granulocytic differentiation-related genes of CD11b , CSF3R , PU.1 , and C/EPBε in HL-60 cells . Furthermore, 8:2 FTOH exhibited no effect on intracellular ROS level, while hydralazine hydrochloride (Hyd), one reactive carbonyl species (RCS) scavenger, partially blocked 8:2 FTOH-caused cytotoxicity in HL-60 cells. Overall, the results obtained in the study show that 8:2 FTOH poses immunotoxicity in immature immune cells and RCS may partially underline its mechanism.
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Green Energy & Environment
·
2019
·
IF 0
Xiaolan Deng,Yuqi Jiang,Zengxi Wei,Minglei Mao,Ramyakrishna Pothu,Hongxia Wang,Caiyun Wang,Jinping Liu,Jianmin Ma
Increasing the energy density, power density as well as widening the operation voltage are essential to electrochemical capacitors to meet the practical energy demands. Herein, a novel flexible quasi-solid-state dual-ion asymmetric supercapacitor (ASC) with Ni(OH) 2 and Nb 2 O 5 nanosheets directly grown on stainless steel mesh is developed. In the dual-ion ASC, Nb 2 O 5 negative and Ni(OH) 2 positive electrodes react with Li + and OH − respectively in alkaline gel electrolyte to store energy, which is quite different from conventional alkali metal ion SCs and alkaline SCs. The as-assembled flexible device has an extended working voltage of 1.7 V and delivers a capacity of 5.37 mAh cm −2 , a maximum energy density and power density of 0.52 mWh cm −3 and 170 mW cm −3 , respectively. The device maintains around 60% capacity retention after long cycling up to 1000 cycles. Moreover, our device can light up a LED light efficiently upon fast charging. The proposed quasi-solid-state dual-ion ASC has potential applications in future portable electronics and flexible energy storage devices.
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ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
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2019
·
IF 3.061
Jianying Bai,Zhen He,Yaofu Li,Xuexia Jiang,Hongmei Yu,Qing Tan
Mono-2-ethylhexyl phthalate (MEHP) is a major bioactive metabolite in the widely used industrial plasticizer diethylhexyl phthalate (DEHP) that has been found to be toxic to the liver. The aim of this study is to determine whether MEHP exposure can change the expression of fatty acid metabolism-related genes in HepG2 cells, which might be related to non-alcoholic fatty liver disease (NAFLD). The results revealed that exposure to MEHP promoted lipid accumulation in HepG2 cells. The levels of intracellular triglycerides in the hepatocytes increased after exposure to 0.8–100 μM MEHP for 24 h and 48 h. The genetic expressions of SREBP-1c, ChREBP, ACC1, FASN, and SCD significantly increased at 6 h after exposure to MEHP. At 24 h, the expression of the SREBP-1c and ChREBP genes remained increased, while the expression of the FASN and SCD genes decreased. At 48 h, the expression of SREBP-1c, ChREBP, ACC1, FASN, and SCD decreased. Furthermore, the levels of proteins including ACC1, FASN, SCD, and ChREBP (except SREBP-1c) increased at 24 h. These findings suggest that MEHP exposure can promote fatty acid synthesis in hepatocytes by regulating the expression of relevant genes and proteins, contributing to NAFLD.
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Frontiers in Chemistry
·
2019
·
IF 3.782
Cai Guangming,Yang Shaoqi,Zhou Qing,Liu Lifei,Lu Xingmei,Xu Junli,Zhang Suojiang
In order to obtain the regularities of physicochemical properties of hydroxy protic ionic liquids (PILs) and broaden their potential application, a series of 2-hydroxyethylammonium sulfonate-based PILs were synthesized through proton transfer reaction and characterized by NMR and FT-IR and elemental analysis. Their phase transfer behavior (Tm) and initial decomposition point (Td) were characterized by differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA), respectively. Meanwhile, the regularities of density (ρ), viscosity (η) and electrical conductivity (σ) of synthesized PILs at different temperatures were measured. The results indicated that their physicochemical properties were tightly related with their structures and the interactions between cations and anions. In addition, the dissociation constants (pKa) of synthesized PILs were obtained by acid-base titration, which revealed that all synthesized PILs had pKa exceeding 7 and their cations were the crux of determining the pKa value. Moreover, several synthesized PILs with a low melting temperature also showed potential application in the deoxidation reaction of cyclohexanol, as they had conversion rates approximating 100% and the selectivity of cyclohexane or cyclohexene was about 80%.
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危险品化学品经营许可证（带存储）