CHEMICAL ENGINEERING JOURNAL
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2026
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IF 12.5
Hongyang Liu,Tiancheng Gao,Jian Zhang,Xin Cheng,Zheng Xing,Lina Li,Haina Bai
Constructed MOF-in-LDHs to regulate morphology and anchor active sites. • Ternary metal redox cycles coupled with ETP boosted PMS activation. • Ion resistance and cycling stability enable continuous-flow application. Although the development of catalysts with high activity and stability is still a major problem, advanced oxidation processes based on peroxymonosulfate (PMS-AOPs) show promise for the degradation of antibiotics. In this work, FeCu-LDH with an initial fish-scale embroidered spherical morphology was reconstructed during ZIF-67 growth, forming a unique 3D structure with ZIF-67 nanoparticles confined on lamellar substrates. This structure not only provides ideal anchoring sites for ZIF-67 but also alleviates its self-agglomeration and metal ion leaching via spatial confinement. Under optimized conditions, 2 mg of the catalyst achieved 95.12% norfloxacin (NOR) removal within 30 min; positively charged LDHs stabilized negatively charged PMS, while ZIF-67 Co sites triggered the continual production of reactive oxygen species (ROS). DFT calculations showed ZIF-67/FeCu-LDH efficiently activates PMS by enhancing adsorption and interfacial electron transfer. A continuous-flow reactor with this catalyst maintained >90% NOR removal for 8 h, showing good practical potential. Quenching experiments and EPR confirmed SO 4 ·- , ·OH, ·O 2 − and 1 O 2 generation; electrochemical tests verified the participation of type III electron transfer pathway (ETP(III)), with radical-non-radical coupling promoting NOR degradation. Mechanistically, FeCu-LDH lamellar confinement enhances Fe/Cu/Co redox cycles and accelerates electron transfer, supplying sufficient electrons for PMS activation. This study proposes a potential method for designing MOF-in-LDHs composites, providing a reference for the treatment of water contaminated by antibiotics.
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高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2026
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IF 19
Wenjia Liu,Nina Zhang,Xu Guo,Xiaofan Zhang,Ying Wang,Jinchao Zhang,Kun Ge,Guoqiang Zhou
Immunotherapy is rapidly emerging as a potent, targeted therapy for breast cancer. However, the low immunogenicity and immunosuppressive tumor microenvironment (TME) in breast cancer limit its efficacy. In this study, a novel nanoreactor, CeO 2 :Mn (CM) embedded with the zeolitic imidazolate framework-90 (ZIF-90) and loaded with 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), is developed and designated CeO 2 :Mn/ZIF-90/ABTS (CMZA). Zn 2+ release from ZIF-90 degradation in the TME triggers pyroptosis and elevates intracellular •O 2 − levels by inhibiting the electron-transport chain. Furthermore, the CM nanozyme exhibits multienzyme activities, including superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT), which convert •O 2 − to H 2 O 2 , generate •OH, produce O 2 , and oxidize ABTS to oxidized ABTS (oxABTS). The oxABTS exhibits strong near-infrared absorption and converts 808 nm light into heat, enhancing CM catalysis and depleting intracellular glutathione (GSH), thereby further amplifying the accumulation of reactive oxygen species (ROS). Collectively, CMZA induces NLRP3/c-Caspase-1/GSDMD-N pyroptosis through Zn 2+ release and photothermal-enhanced multienzyme activity, reshaping the TME and boosting immunogenicity to limit tumor progression and metastasis.
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CHEMICAL ENGINEERING SCIENCE
·
2026
·
IF 5.1
Simin Li,Sen Mu,Jie Ji,Fengbing Tang,Ning Chai,Jingbo Mu,Handan Zeng
Tetracycline hydrochloride (TCH), owing to its structural stability and resistance to degradation, has emerged as a typical persistent pollutant in aquatic environments. However, the development of effective and environmentally friendly strategies for the removal of TCH remains highly challenging, owing to limited pollutant enrichment and low catalyst activation efficiency. In this study, a quartz sand-supported ZIF-8 catalyst functionalized with chitosan-derived N-doped carbon (QN@ZIF-8) was rationally constructed: (1) π–π interactions enhanced the adsorption and enrichment of TCH molecules, thereby significantly increasing the probability of contact between pollutants and active sites and (2) its efficient electron transfer channels accelerated the activation of peroxymonosulfate (PMS), facilitating the directional generation of superoxide radicals (•O 2 − ) and singlet oxygen ( 1 O 2 ), thus strengthening the synergistic pathways of both radical and non-radical degradation. Experimental results demonstrated that under optimal conditions (catalyst dosage: 0.5 g/L, PMS: 0.2 g/L, pH ≈ 5.1), QN@ZIF-8 achieved an efficient removal of 90.5% of TCH within 40 min, with an apparent pseudo-first-order rate constant of k = 0.0393 min −1 , which was 2.1 times higher than that of pristine quartz sand. Moreover, the catalyst maintained a removal efficiency above 82.3% after five consecutive cycles and exhibited stable performance in tap water and simulated seawater. Liquid chromatography-mass spectrometry (LC-MS) revealed three predominant TCH degradation pathways. This study not only elucidates the π-system-driven synergistic catalytic mechanism but also offers new insights into material design and theoretical guidance for the efficient remediation of recalcitrant organic pollutants
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International Journal of Nanomedicine
·
2026
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IF 8.7
Zidong Wu,Kai Ma,Zixuan Wu,Xiaoyu Guo,Yuning Qu,Zheyue Zhu,Weidong Zhu,Chengxin Li,Yi Liu,Rui Ma,Pei Yang
Background Polyetheretherketone (PEEK) is a promising orthopedic implant material due to its bone-matched elastic modulus and radiolucency. However, its clinical application is limited by biological inertness and lack of antibacterial activity, which predispose to implant-associated infection (IAI) and poor osseointegration. This study developed a multifunctional coating on sulfonated PEEK (SPEEK) via polydopamine (PDA)-mediated co-delivery of simvastatin-loaded ZIF-8 nanoparticles (SIM@ZIF-8) and moxifloxacin (MOX) to address these limitations.Methods A time-programmed release coating was fabricated on SPEEK by embedding SIM@ZIF-8 within a PDA layer and surface-loading MOX onto the surface. The coating’s physicochemical properties, drug release profiles, biocompatibility, antibacterial activity, and osteogenic capacity were evaluated in vitro. Antibacterial efficacy and osseointegration were further assessed in vivo using rat subcutaneous infection and rabbit femoral defect models.Results Release profiles revealed that MOX exhibited burst release within 24 h, whereas SIM quickly reached therapeutic concentrations during the initial phase and was slowly released over five weeks, while Zn2+ from ZIF-8 was released synchronously with SIM. In vitro antimicrobial assays showed that the synergistic release of MOX and SIM exhibited potent antibacterial activity against Staphylococcus aureus and Escherichia coli, providing sustained inhibition of Staphylococcus aureus biofilms. The coating also promoted MC3T3-E1 cell adhesion, spreading, and osteogenic differentiation, as indicated by upregulated osteogenic markers (Runx2, OCN, OPN, COL1A1), enhanced matrix mineralization, and increased BMP-2 expression. In rat models, bacterial colonization on the coated surface and residual bacteria in tissues were significantly reduced. In rabbit femoral defects, sustained co-release of SIM and Zn2+ accelerated new bone formation and improved osseointegration, confirmed by micro-CT, double fluorescence labeling, and histological analysis.Conclusion This study presents a novel bioactive PEEK implant coating integrating antibacterial and osteogenic functions through a MOX/SIM@ZIF-8/PDA system. The strategy effectively combats IAI and enhances osseointegration, offering potential for clinical orthopedic applications.
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PubMed
高影响因子
Materials Today Communications
·
2026
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IF 4.9
Wenhui Pei,Xiaofei Li,Haojun Chen,Xiangrong Guo,Jinhui Pang,Yingjie Du,Yuanyuan Xie,Peng Wang,Caoxing Huang
The intertwined pathology of bacterial infection and dysregulated inflammation represents a major barrier to the healing of full-thickness skin wounds. Nanocarriers such as zeolitic imidazolate framework-8 (ZIF-8) provide efficient platforms for localized and pH-dependent drug delivery. In this study, a ZIF-8 nanoparticle system co-embedded with vancomycin (Van) and iron oxide nanoparticles (IONPs), termed Van-IONPs@ZIF-8, was engineered to combine antibacterial and inflammation-modulating functions. In vitro experiments demonstrated growth-inhibitory activity against Staphylococcus aureus ( S. aureus ) and modulation of inflammatory cytokine expression in LPS-stimulated RAW 264.7 macrophages, with TNF-α mRNA expression decreased by 67% and IL-10 mRNA expression increased by 244%. The nanocomposite was incorporated into a triple-crosslinked hydrogel matrix, and the resulting Van-IONPs@ZIF-8-Gel exhibited sustained and pH-dependent Van release under the tested conditions. In a rat full-thickness S. aureus -infected wound model, Van-IONPs@ZIF-8-Gel treatment was associated with improved wound closure, lower recoverable bacterial colony counts, attenuated inflammatory markers, and increased collagen-positive area. These findings provide proof-of-concept evidence supporting Van-IONPs@ZIF-8-Gel as an integrated antibacterial and inflammation-modulating platform for infected-wound management. Download: Download high-res image (248KB) Download: Download full-size image An engineered ZIF-8 composite hydrogel co-delivering vancomycin and iron oxide nanoparticles provides combined antibacterial and inflammation-modulating functions.
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高影响因子
MICROCHEMICAL JOURNAL
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2026
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IF 5.2
Biaobiao Ge,Jie Huang,Qianmin Dong,Fen Yang,Mengmeng Wang,Pei Liang
This work reveals a novel SERS enhancement mechanism of “satellite” structure. • Stable and uniform L-Au@ZIF-67@S-Au NPs were synthesized by self-assembly method. • L-Au@ZIF-67@S-Au NPs substrates was prepared with an enhancement factor of 3.4 × 10 6 . • Determination of fenpropathrin in citrus peel, and its LOD reached 0.995 μg/L. A new hybrid substrate of core-satellite plasma MOF, namely L-au @ ZIF-67 @ S au NPs, was developed in this study. The substrate aims to improve SERS performance by combining the molecular trapping layer of ZIF-67 with double electromagnetic hot spots distributed on the inner surface and the outer surface. The interface self-assembly strategy was adopted to combine MOF with plasma nanostructures, thus combining excellent molecular adsorption ability with strong local field enhancement effect. The results showed that the substrate had a low detection limit of 1.43 × 10 −10 M for rhodamine 6G, achieved rapid adsorption equilibrium within 10 min, and showed high signal reproducibility (relative standard deviation, RSD = 1.66%, n = 20). The substrate was applied to the detection of fenpropathrin residues in citrus peels, showing good sensitivity, and the detection limit was 0.995 μg·L −1 , with an enhancement factor of 3.4 × 10 6 and excellent reproducibility. This work builds a multifunctional and environment-friendly SERS platform, which effectively combines advanced nano-material design with practical applications of food safety monitoring Download: Download high-res image (146KB) Download: Download full-size image
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Applied Materials Today
·
2026
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IF 7
Xiaowan Zhao,Qikai Qiao,Yuanqing Li,Aiqin Zhang,Hong Guo,Jing Guo,Haixia Zhang,Jianjun Lu
To address the issue of secondary contamination caused by the lack of antibacterial properties in polypropylene (PP) meltblown nonwoven fabrics while preserving its core filtration performance, this work employed an immersion-ultrasonic method to construct Ag@T-ZIF-8 antibacterial materials with a core-shell structure. Subsequently, PP/Ag@T-ZIF-8-G composite meltblown fibers was prepared via covalent modification and meltblown spinning technology. The systematic characterization of Ag@T-ZIF-8 was conducted in terms of its chemical structure, microstructure, and photocatalytic antibacterial performance. The effects of Ag@T-ZIF-8 on the antibacterial, filtration and comfort properties of the composite melt-blown nonwoven fabrics were investigated, and the enhancement mechanisms of antibacterial and filtration were revealed. The results indicate that Ag@T-ZIF-8 exhibits a uniform core-shell structure with a particle size of 40∼50 nm and a specific surface area of 531.83 m²/g. At an antibacterial concentration of 200 mg/L, it achieves a 99.99% antibacterial rate against Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. aureus ) within 8 min in the dark or 4 min under illumination. Compared with PP meltblown nonwoven fabrics, it demonstrates 73.31% in filtration efficiency for particles with a pressure drop of only 37.3 Pa. When Ag@T-ZIF-8 loading reaches 1 wt%, the composite meltblown fabrics completely eliminates E. coli and S. aureus after 160 min of illumination or 240 min in the dark. This outstanding comprehensive filtration performance stems from a synergistic filtration mechanism combining mechanical filtration, ionic adsorption, and dual-mode antibacterial action under light or dark condition. Integrating superior filtration capabilities, broad-spectrum antibacterial properties, and wear comfort, PP/Ag@T-ZIF-8-G meltblown nonwoven fabrics deliver a highly efficient integrated antibacterial-filtration solution for the medical protective field.
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SEPARATION AND PURIFICATION TECHNOLOGY
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2026
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IF 9.1
Hao Zhan,Wenlong Chen,Xingyu Pei,Hao Wang,Bing Zhao,Xiefei Wang,Qingqing Liang,Yukang Xu,Weiwei Zhu
Highly diffuse cationic dyes and copper ions are normal pollutants in dye wastewater and pose a potential ecological risk, threatening human health. However, current MOF-based fibrous composites usually scarify their stability of active sites for photocatalytic reaction, which inevitably causes nondurable removal of these diffuse particles. Here, an in situ growth strategy was proposed to fabricate robust core-shell heterostructure of ZnO@ZIF-8 nanorods which were anchored within polytetrafluoroethylene (PTFE) micro-scale fibers by the solution-blowing spinning (SBS) technique to achieve ZnO@ZIF-8/PTFE hierarchical fibrous networks (ZZP-HFN). It presents superior degradation of cationic dyes (over 97%) and durable decompose stability of more than 20 cycles, and prominent adsorption capacity for copper ions (86.53 mg/g). Moreover, contrast to the existing MOF-based fibrous membranes, ZZP-HFN exhibits the self-cleaning performance on account of its stable composite structure between ZnO@ZIF-8 nanorods and PTFE fiber. The cationic dyes removal of ZZP-HFN from wastewater is attributed to the synergistic effect of adsorption and photocatalytic ability. This work provides an insight to design advanced MOF-based composites with durable photocatalytic performance for dye wastewater purification.
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高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2026
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IF 9.6
Yuze Jiao,Zeyuan Li,Haoyu Zheng,Huiqi Jiangjia,Hui Yang,Qilong Zhang
The thermally conductive functional material ZIF-8/BN was co-loaded onto the fiber via electrostatic self-assembly. • The effects of stabilization heat treatment on the morphology and properties of the reinforcement were investigated. • The roles of uniform ZIF-8 and ZIF-8/BN nanoparticles loaded at the resin-reinforcement interface were analyzed. • Composites obtained solely via reinforcement functionalization showed excellent thermal expansion and thermal conductivity. Polytetrafluoroethylene (PTFE) is widely used in high-frequency substrate materials due to its favorable dielectric constant and excellent thermal stability. However, its high coefficient of thermal expansion (CTE) and low thermal conductivity cause some processing challenges. Herein, we report a modified reinforcement, designated ZIF-8/BN@GF (ZB@G), which was fabricated by electrostatically assembling thermally conductive BN (boron nitride) with the metal-organic framework (MOF), followed by in-situ growth onto glass fibers (GF) through an impregnation process. Thermal stabilization was found to markedly enhance the structural compactness and moisture resistance of the fibers during processing. The rough surface morphology of the MOF facilitates mechanical interlocking and resin infiltration into its porous structure, thereby strengthening the interfacial bonding between the reinforcement and the resin matrix and consequently improving the dimensional stability of the composites. Moreover, the uniform distribution of flat BN nanosheets along the fiber surface serves to regulate interfacial interactions, establish oriented thermal conduction pathways, and simultaneously tailor the thermal expansion behavior. As a result, the resulting PTFE composites exhibit a suitable in-plane CTE parallel to the reinforcement of 16.97 ppm/°C and a maximum thermal conductivity of 1.481 W·m −1 ·K −1 . In addition, they retain excellent dielectric properties, achieving a low dielectric constant of 2.39 and a low dielectric loss of 0.00145 at 10 GHz. This work demonstrates that a straightforward in-situ loading of nano-functional materials onto reinforcements can concurrently deliver substantial improvements in thermal conductivity and mechanical performance, providing a promising strategy for the selection of reinforcements in next-generation high-frequency substrate materials. Download: Download high-res image (155KB) Download: Download full-size image
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高影响因子
ENVIRONMENTAL RESEARCH
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2026
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IF 8.2
Yisong Zhu,Ying Zhou,Zhikai Zhu,Guangfeng Zhang,Wei He,Yumei Chen,Pengchao Li,Weichong Long,Shuohai Fang,Hui Luo,Changzhong Liao
Efficient capture of radioactive iodine isotopes from nuclear waste is crucial for environmental protection and human health. In this study, a high-entropy strategy was introduced into the zeolitic imidazolate framework-8 (ZIF-8) system to overcome the inherent limitations of conventional monometallic ZIF-8 and to elucidate entropy-regulated iodine capture behavior. Using a solvothermal method assisted by triethylamine (TEA), a series of ZIF-8 derivatives with entropy levels ranging from low to high were successfully synthesized to explore the relationship between entropy level and iodine adsorption performance. Furthermore, given that Cd incorporation has been reported to enhance the structural flexibility of ZIF-8, the influence of different Zn/Cd ratios was investigated. Characterization results showed that although TEA enhanced the doping efficiency of poorly coordinating metal ions, it simultaneously reduced crystallinity and BET surface area, leading to pore blockage and a substantial decline in iodine adsorption performance. Iodine adsorption did not show a positive correlation with increasing compositional complexity. The synergistic effects of multimetal nodes did not improve the iodine uptake capacity of ZIF-8, and the high-entropy ZnCdCoMgNi-ZIF-8 exhibited the lowest iodine uptake capacity (1.10 g⋅g −1 ). In contrast, Cd doping increased the iodine uptake capacity to 2.80 g g −1 in phase-pure Cd-ZIF-8, corresponding to a 2.2-fold enhancement over conventional ZIF-8. Moreover, a structural phase transition was induced during iodine adsorption in Cd-rich systems. This work provides important insights into the design of high-performance iodine capture materials and highlights the potential of cadmium-modified ZIF-8 derivatives as promising adsorbents.
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JOURNAL OF HAZARDOUS MATERIALS
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2026
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IF 10.6
Hanlin Li,Shuangqin Tian,Xin Wang,Yujing Long,Tianhong Ye,Lihong Tang
When used individually, ZIF-8 suffers from hydrolysis in aqueous media, while CAU-17 is limited by its low specific surface area (64.71 m²/g). Therefore, we employed an in situ self-assembly strategy to construct a MOF-on-MOF heterostructure (CAU-17@ZIF-8) for the synergistic removal of Cd(II) and methylene blue (MB). The composite achieved maximum adsorption capacities of 607.65 mg/g for Cd(II) and 1025.38 mg/g for MB, with a 99% removal efficiency for low-concentration pollutants in real wastewater. Even after five cycles, 75% efficiency was maintained. Mechanistic studies combining batch experiments, characterization, and DFT calculations revealed that the heterojunction interface promotes substantial charge transfer from CAU-17 to ZIF-8, significantly enhancing electrostatic attraction toward cations. Simultaneously, new mesopores formed at the interface increase the specific surface area (239.62 m 2 /g) and provide rapid mass-transfer channels. MB adsorption is governed by electrostatic attraction, hydrogen bonding, and π-π interactions, while Cd(II) adsorption relies on ion exchange, coordination, and electrostatic attraction. This work demonstrates that constructing MOF-on-MOF heterojunctions is a promising strategy to overcome the intrinsic limitations of single MOFs in water remediation, thereby greatly enhancing the adsorption capacity toward methylene blue (MB) and Cd(II).
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高影响因子
CATALYSIS LETTERS
·
2026
·Vol. 156
·期 9
·261
·
IF 2.5
Su Qiqi,Dai Wanrong,Liu Meijun,Cheng Mengyu,Dai Chunyan,Li Yafei
The rational design of non-noble metal catalysts relies on a deep understanding of the structure-performance relationship. Herein, we investigate the influence of pyrolysis temperature (800–1100 °C) on Co–N/C catalysts derived from ZnCo-ZIF for the aerobic oxidation of 5‑hydroxymethylfurfural (HMF) to 2,5‑furandicarboxylic acid (FDCA). A volcano‑shaped dependence of FDCA yield on pyrolysis temperature is observed, with the catalyst pyrolyzed at 1000 °C (Co–N/C-1000) delivering complete HMF conversion and 98.0% FDCA yield within 4 h under optimized conditions (110 °C, 2 MPa O 2 ). Multi-technique characterization reveals a temperature-driven evolution of Co species: from atomically dispersed Co–N x sites at 800–900 °C, to a bimodal configuration comprising abundant Co–N x together with a small amount of metallic Co 0 nanoparticles at 1000 °C, and finally to large Co aggregates at 1100 °C. The optimal catalytic performance at 1000 °C is thus attributed to this unique coexistence. Kinetic analysis confirms the consecutive pathway HMF → HMFCA → FFCA → FDCA with FFCA→FDCA as the rate‑determining step. Notably, the optimal catalyst maintains 96.8% FDCA yield under industrially relevant 5 wt% HMF concentration. This work provides insights into the structure-performance relationship of Co–N/C catalysts and a rational strategy for designing efficient non-noble metal catalysts for biomass conversion. Graphical
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