SURFACE & COATINGS TECHNOLOGY
·
2018
·
IF 2.906
Wenfu Chen,Limin He,Yi Guo,Xiao Shan,Jianghua Li,Fangwei Guo,Xiaofeng Zhao,Na Ni,Ping Xiao
The CeO 2 , Y 2 O 3 and HfO 2 doped β-NiAl coatings with controlled concentrations were fabricated on Hastelloy substrates using spark plasma sintering . The effects of reactive element oxide (REO) species and concentrations on the isothermal oxidation of the β-NiAl coatings were investigated. It was found that the addition of Y 2 O 3 and HfO 2 improved the oxidation performance of β-NiAl coatings, but CeO 2 with high concentrations (0.5 at.%) had a detrimental effect . At low concentration (0.05 at.% and 0.1 at.%), HfO 2 was less effective in improving the oxidation resistance of β-NiAl compared with Y 2 O 3 and CeO 2 , while HfO 2 at higher concentration of 0.5 at.% was the most effective among the three. The effects of REO species and concentrations on the NiAl oxidation behavior were further discussed in related to the intrinsic properties of the REOs and the chemical compositions of the substrate.
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ACS Applied Nano Materials
·
2024
·
IF 5.3
Renjie Jin,Jinsong Liu,Shiwei Chen,Hongde Wang,Changsheng Niu,Xuehua Zhang,Chao Wu,Haizheng Hu,Kai Chen,Daoyou Guo,Shunli Wang
Solar-blind ultraviolet (UV) photodetectors play a critical role in ultraviolet communication and monitoring, effectively reducing false alarm rates and improving the accuracy of detection systems across various settings, which has garnered significant attention. Due to its exceptional solar-blind photon absorption coefficient, extremely stable structure, and ultrawide bandgap (4.5–4.9 eV), Ga2O3 has recently been identified as a desirable material for solar-blind UV photodetectors. Heterojunctions can separate photogenerated electron–hole pairs and their absorption edges can be controlled by selecting semiconductors with appropriate bandgaps, making them an important technology for light detection. In this work, a self-powered solar-blind UV photodetector has been fabricated using a mechanically separated β-Ga2O3/Lu2O3 core–shell microwire heterostructure. Our device demonstrates excellent solar-blind UV discriminability with self-powered photodetection, the device exhibits a responsivity of 38.8 mA/W, a detectivity of 1.22 × 1012 Jones, a switching ratio of 1.43 × 103, and a decay rate under UV irradiation of 62 ms, benefiting from both photovoltaic and photoconductive effects. Due to the high dielectric constant of Lu2O3 thin films at the nanoscale, enables more effective modulation of internal electric fields within heterojunction structures, thereby enhancing the response speed and sensitivity of photodetectors. The application of self-powered photodetectors in solar-blind communication systems has achieved promising results, which provides a viable strategy for Ga2O3-based high-performance self-powered photodetectors.
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JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY
·
2026
·
IF 1.4
Liu Qi,Yang Yu,Guo Cheng,Ding Sha,Liang Qiuju,Deng Changjian,Wang Zhiguo,Hu Yaonan,Wu Yu,Xie Shenglin,Zhang Ling,Cui Yuqi,Wang Qing
The development of an oral delivery system enabling rapid release of nicotine salts represents a promising strategy for advancing nicotine replacement therapy. In this study, nicotine hydrogen tartrate inclusion complexes (CDNS-NHT) were fabricated using β-cyclodextrin nanosponges (CDNS) as carriers. We systematically investigated how CDNS synthesized at different β-cyclodextrin (β-CD): diphenyl carbonate (DPC) molar ratios affected drug-loading performance, and the resulting complexes were characterized through multiple analytical techniques. Molecular docking studies revealed a binding energy of -5.492 kcal/mol between nicotine hydrogen tartrate (NHT) and CDNS, demonstrating that inclusion complex formation is thermodynamically favorable. Encapsulation efficiency reached an optimal value of 77.24 ± 6.44% at a β-CD: DPC molar ratio of 1:4. Fourier transform infrared spectroscopy and thermogravimetric analysis confirmed the successful encapsulation of NHT within CDNS, alongside significantly enhanced thermal stability. In vitro release studies demonstrated rapid dissolution characteristics, achieving a cumulative release of 74.00 ± 5.38% within 5 min under simulated oral conditions. Cytotoxicity assays further revealed that CDNS-NHT maintained cell viability exceeding 90% in both human oral keratinocytes (HOK-16B) and oral squamous cell carcinoma cells (SU4-02), indicating its favorable biocompatibility. This delivery system integrates excellent stability, efficient solubilization, and rapid oral release properties, presenting considerable potential for applications in nicotine replacement therapy.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2022
·
IF 5.518
Weimin Wan,Ziqi Li,Xi Wang,Fei Tian,Jian Yang
Improving the biocompatibility and water dispersibility of hydroxyapatite (HAP) is an effective way to expand its application in biomedicine. Here, we present a nanosystem (HAP-β-CD-HPG) that is constructed by riboflavin sodium phosphate (HE) functionalized hydroxyapatite (HAP) and hyperbranched β-cyclodextrin (β-CD-HPG) through a simple, mild and rapid approach. Firstly, the successful construction of HAP-β-CD-HPG nanosystem is confirmed by transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS) and so on. Next, Doxorubicin (DOX) is loaded onto HAP-β-CD-HPG with a high encapsulation potency (60.3%) and further use for the simultaneously cell-imaging and controlled release of the cytotoxic drug DOX. Furthermore, the pH-triggered DOX release process in A549 cancer cells can be visualized dynamically by tracking the fluorescence of HAP-β-CD-HPG and DOX. This work both provides a new protocol for the construction of dual-function nanosystem for imaging of cell cytoplasm and drug delivery via a simple approach and promotes a potential application of this diagnosis-therapy integrated system for cancer treatment in the future.
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JOURNAL OF FOOD ENGINEERING
·
2026
·
IF 5.8
Fuge Niu,Yuxian Long,Chunxiao Wang,Huabin Liao,Feina Gu,Zhijuan Feng,Jianzhong Zhou,Mengdi Zhao,Weichun Pan
Glycosylation enhanced EWP emulsifying capacity for stable HIPEs. • HIPEs formed jammed droplet networks with viscoelastic behavior. • Interfacial adsorption governed droplet size and microstructure. • Dense interfacial layers improved β-carotene stability (>90%). • Optimal conjugate level (1.5%) maximized bioavailability (+146%). High internal phase emulsions (HIPEs) are promising carriers for lipophilic bioactives; however, their structural stability and digestive performance are highly dependent on interfacial design. In this study, egg white protein (EWP)–xylan oligosaccharide (XOS) maillard conjugates were used to fabricate food-grade HIPEs, and their effects on interfacial adsorption, microstructure, rheological behavior, and delivery functionality were systematically investigated. Glycosylation significantly improved the emulsifying performance of EWP, enabling the formation of stable HIPEs with a maximum oil phase fraction ( ϕ ) of 0.87 at 2.0% conjugate concentration, while a minimum concentration of 0.4% was sufficient at ϕ = 0.80. Increasing conjugate concentration enhanced interfacial adsorption, reduced droplet size, and promoted the formation of a densely packed, jammed droplet network, resulting in concentration-dependent viscoelastic properties. Furthermore, HIPEs effectively improved the thermal and storage stability of β-carotene, with retention exceeding 90% after 30 days, which was attributed to the formation of a dense interfacial barrier that limited mass transfer. In vitro digestion revealed that lipid hydrolysis and β-carotene bioaccessibility were maximized at 1.5% conjugate concentration, reflecting a balance between structural stability and enzymatic accessibility. Overall, this study establishes a structure–function relationship in EWP–XOS-stabilized HIPEs and provides mechanistic insights for designing protein–polysaccharide-based delivery systems for lipophilic bioactive. Download: Download high-res image (339KB) Download: Download full-size image
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ACS Sustainable Chemistry & Engineering
·
2026
·Vol. 14
·期 29
·13042-13055
·
IF 7.6
Lau Chun-Yin,Li Xinwei,Zhang Yanlin,Rangarajan Goutham,Tse Ho-Yin,Zhuang Huichuan,Leu Shao-Yuan,Farnood Ramin R.
In this study, an amorphous carbon-rich carbon nitride photocatalyst was prepared by nitric acid treatment of pyrolyzed melamine followed by nitrogen annealing. The resulting semiconductor material exhibited an up-shifted valence band that enhances the oxidizing power of photogenerated holes, enabling selective C α −C β bond cleavage of 2-phenoxy-1-phenylethanol (2-POE). Using 1.5 g L −1 of the optimized photocatalyst in acetonitrile, 2-POE underwent first-order conversion with a reaction rate of 2.55 h −1 under a 9 W blue LED light source. Product analysis showed the formation of benzaldehyde as the major product, confirming C−C bond scission with 93.1% selectivity. In addition, ring-opening reactions were observed, producing fumaric and maleic acids as the by-products. Photocatalytic depolymerization of organosolv lignin further demonstrated ring opening of the β-O-4 linking motifs, forming dicarboxylic acids analogous to those generated from 2-POE. These demonstrate a metal-free photocatalytic platform capable of promoting β-O-4 bond cleavage in lignin model compounds and inducing photocatalytic structural modification of organosolv lignin, accompanied by the formation of low-molecular-weight aliphatic dicarboxylic acids.
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JOURNAL OF APPLIED POLYMER SCIENCE
·
2026
·
IF 3.1
Bo Zhu,Shijie Xu,Yu Feng,Weijie Xu,Ji Liu,Xinlao Wei
Surface flashover is a common insulation failure in high-voltage equipment. Conventional anti-flashover coatings can raise flashover voltage, but scratches and microcracks often reduce their long-term reliability because most coatings cannot repair damaged interfaces. Here, a self-healing anti-flashover coating was prepared by introducing β-cyclodextrin–adamantane host–guest units into a fluorocarbon resin (FEVE) matrix. Quantum chemical calculations, molecular dynamics simulations, and electrical tests were used to examine host–guest stability, trap regulation, charge dissipation, scratch healing, and DC flashover behavior. The β-CD–Ad inclusion structure was thermodynamically favorable and remained stable during simulation. HG incorporation changed the surface trap distribution of FEVE and promoted charge transport by introducing high-density shallow traps. The 10 wt% HG/FEVE coating showed the best overall performance, with a DC flashover voltage 15.12% higher than that of pure FEVE. After damage and water-assisted repair, it retained 96.57% of its flashover performance. The improved performance is attributed to two coupled effects: reversible host–guest interactions help close damaged interfaces, while shallow-trap-dominated charge transport reduces surface charge accumulation and local electric-field distortion. This work offers a route for designing repairable anti-flashover coatings for high-voltage insulation.
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CHEMISTRY & BIODIVERSITY
·
2026
·Vol. 23
·期 7
·e71476
·
IF 2.9
Changchang Gao,Zefeng Xia,Chengwei Xu,LeiFang Zhang,Chengjie Tong,Chunyu Niu,Boyi Fan,Yan Chen,Yin Chen
Sporisorium reilianum ( S. reilianum ) is an agricultural pathogen that causes disease and reduces yield in sorghum and maize crops. However, head smut-infected sorghum and maize have been traditionally utilized for edible and medicinal purposes in some regions. In this study, the structure and immunostimulatory potency of a new slightly branched β-glucan WM-0.25(P) obtained from the S. reilianum -infected sorghum head smut were explored. WM-0.25(P) was a β-glucan with a molecular weight of 69.67 kDa and was composed of β-1,6-D-Glcp as the main chain and β-1,3-D-Glcp as the side chain. There was approximately one branch for every 11 sugars on the main chain. WM-0.25(P) triggered morphological alterations, enhanced phagocytic activity, and upregulated the expression of surface molecules, while promoting the production of ROS, NO, and pro-inflammatory cytokines (IL-6, TNF-α, IL-1β) in RAW264.7 macrophages. The function blocking antibodies to toll-like receptor revealed that TLR4 mainly participated in the recognition and immunostimulatory function of WM-0.25(P). Simultaneously, WM-0.25(P) modulated macrophage inflammatory response mainly through activation of the TLR4/MyD88/NF-κB signaling pathway. The results indicated that WM-0.25(P), with a low branching degree derived from S. reilianum -infected sorghum head smut, exerted moderate immunomodulatory effects on macrophages. Further in vivo studies are warranted to evaluate its translational potential. Graphical This β-glucan (69.67 kDa) from S. reilianum -infected sorghum has a β-1,6 backbone with β-1,3 branches. It moderately activates RAW264.7 macrophages via TLR4/MyD88/NF-κB, promoting cytokine/ROS/NO production and phagocytosis.
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JOURNAL OF POLYMER SCIENCE
·
2026
·
IF 3.9
Jiangtao Guo,Hongxiang Ou,Wenqian Zhou,Honglai Xue,Fang Zhu,Weikang Liu
In this work, a core–shell flame retardant (MF@β-CD) was prepared by coating β-cyclodextrin (β-CD) with melamine-formaldehyde (MF) resin through in situ polymerization. Amino-functionalized attapulgite (ATP-NH 2 ) was also prepared via silane modification. MF@β-CD and ATP-NH 2 were incorporated with piperazine pyrophosphate (PAPP) to fabricate flame-retardant PP composites through melt blending. The incorporation of MF@β-CD and ATP-NH 2 improved the fire performance and thermal stability of PP composites. The PP composite containing the MF@β-CD/ATP-NH 2 system exhibited a limiting oxygen index (LOI) of 33.8% and achieved a UL-94 V-0 rating. Compared with neat PP, the peak heat release rate and total smoke production decreased by 91.9% and 87.7%, respectively. Thermal analysis and char characterization suggested that the MF@β-CD/ATP-NH 2 system promoted the formation of a more continuous and stable char layer during combustion. The MF shell contributed to improved interfacial compatibility between β-CD and the PP matrix, while ATP-NH 2 helped maintain the integrity of the char structure. This work provides a feasible approach for improving the fire safety and condensed-phase stability of PP using bio-based flame-retardant components. Graphical Core–shell structured MF@β-CD was prepared via in situ polymerization and combined with amino-modified attapulgite (ATP-NH 2 ) and piperazine pyrophosphate (PAPP) to synergistically modify polypropylene (PP). The optimized composite achieved a limiting oxygen index (LOI) of 33.8% and a UL-94 V-0 rating. The incorporation of ATP-NH 2 resulted in a distinct lamellar stacking structure on the char residue surface, with the layered silicate sheets of ATP-NH 2 uniformly embedded in the organic char matrix. This enhanced the structural stability and thermal shock resistance of the char layer, preventing its cracking and peeling during high-temperature combustion.
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ACS Applied Polymer Materials
·
2026
·
IF 5.2
Huang Yanmin,Chen Yanlin,Li Jiansheng,Hu Qiang,Liu Zhiping,Xiong Qipeng,Gan Chunfang,Cui Jianguo
A β-cypermethrin
(CY) nanoformulation (CY@β-CDs/SE)
was constructed via a dual-carrier coencapsulation strategy utilizing
β-cyclodextrin octadecanoate (β-CDs) and starch hexadecanoate
ester (SE). This system leverages the host–guest inclusion
of pesticide molecules within the hydrophobic cavity of β-CDs,
followed by assembly with SE into an outer barrier via hydrophobic
interactions between β-CD and SE side chains, supplemented by
van der Waals forces and interfacial hydrogen bonding. The formulation
significantly enhanced the stability of the active ingredient, exhibiting
a thermal storage degradation of 3.47%, which was 20.4% and 59.0%
lower than those of the single-carrier CY@β-CDs and CY microemulsion
(CYm), respectively. The photolysis half-life ( T 50 ) of CY@β-CDs/SE reached 76.2 h, representing a 75%
and 127% extension compared to CY@β-CDs and CYm, respectively.
Sustained-release studies demonstrated a cumulative release of 79.0%
after 302 h in 20% methanol–water, and release increased markedly
under alkaline (pH = 9) or elevated temperatures (45 ° C), with
dual pH/temperature-responsive behavior. CY@β-CDs/SE maintained
68% insecticidal lethality 25 days postapplication, outperforming
CY@β-CDs (48.0%) and CYm (34.7%). Furthermore, CY@β-CDs/SE
substantially improved the biosafety of β-cypermethrin, achieving
a 96h LC 50 value of 24.7 μg/L in zebrafish , 2.1-fold higher than that of CYm (11.7 μg/L), while also
enhancing the biosafety for rice seed germination. This study establishes
an intelligent delivery system using biodegradable materials, offering
a strategy for pesticide reduction and advancing sustainable agricultural
practices.
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Cell Reports
·
2026
·Vol. 45
·期 6
·
IF 7.7
Yifang Chen,Qian Zhang,Na Li,Zhaoqi Zhang,Tong Lei,Han Guo,Hezhe Lu,Yong Zhao
Dendritic cells (DCs) are professional antigen-presenting cells that exhibit significant heterogeneity in development and function. This study found that among 17 cytokines screened, only IL-33 could induce DCs to display a Th9-type cytokine profile, including IL-9, IL-4, and IL-13, in vitro . The response of DCs to IL-33 was synergistically enhanced by TGF-β and IL-4, defining a distinct subset termed DC9. Transcriptomic analysis revealed that DC9 possesses a unique gene expression signature, particularly in cytokine/chemokine clusters, compared to conventional DCs. Mechanistically, DC9 polarization depends on the JAK-STAT6-IRF4 signaling pathway. Functionally, DC9 preferentially drives naive CD4 + T cell differentiation toward Th9 cells in vitro . In an ovalbumin-induced allergic airway inflammatory mouse model, DC9 cells were detectable in lungs and adoptive transfer of DC9 exacerbated disease severity, and increased pulmonary Th9 cells. Collectively, we identify DC9 as a novel DC subset induced by IL-33/TGF-β/IL-4 through the JAK-STAT6-IRF4 axis, which promotes Th9 differentiation and aggravates allergic airway inflammation.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2026
·
IF 4.8
Mohammad Imran,Muhammad Ashfaq Ahmad,Akhtar Hayat,Essam R.I. Mahmoud,Cong Kong,Mian Hasnain Nawaz
This study reports the development of β-CD/GO and TMB based fluorescent sensing system synthesized via a facile hydrothermal approach for sensitive detection of ascorbic acid (AA) in food matrices. The structural and surface characteristics of such nanohybrid were confirmed by XRD, FTIR, Raman, zeta potential, and particle size analysis, while microscopic investigations revealed uniform surface modification of the nanosheets. In analytical studies, a fluorescence quenching based sensing mechanistic system was demonstrated through host guest molecular recognition and photoinduced electron transfer (PET) upon the introduction of AA. The synergistic integration of GO, and host guest recognition capability of β-CD, along with its strong quenching efficiency, enabled precise detection of AA. Under the optimized conditions, the sensor exhibited a linear response over the concentration range of 2.5–40 μM, with a detection limit of 1.21 μM. Furthermore, the developed probe was successfully applied to real food samples, including lemon, mango, and orange juices with recoveries of 92.3–106.4%. Overall, this work presents a rapid, cost-effective, and portable fluorescence-based strategy for practical food safety analysis.
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