COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2023
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IF 5.2
Shujuan Zhang,Yanpeng Mao,Lai Wei,Zhanlong Song,Xiqiang Zhao,Wenlong Wang
The use of thermal conversion to convert Chinese patent medicines (CPM) residues into porous carbon-based materials and carbon dots (CDs) has effectively resolved the challenges associated with resource waste and environmental pollution while enhancing the added value of CPM residues. In this study, biochar and N-doped CDs with high quantum yield (QY) were simultaneously prepared from fermentation residues by employing a hydrothermal carbonization method without any chemical reagents . The obtained biochar had remarkable adsorption capacity, with an iodine adsorption value of 693.22 mg g –1 . The QY of N-doped CDs could reach to 36.17 % by the mean of self-doping due to the high nitrogen content of the fermentation residues. Considering the structural integrity and permeable porous structure of the two-dimensional leaf-like zeolitic imidazole framework (ZIF-L), N-doped CDs were encapsulated into ZIF-L to form novel fluorescent composites (N-doped CDs@ZIF-L). Moreover, N-doped CDs@ZIF-L as a novel fluorescent probe could be efficiently quenched in the presence of tetracycline (TC), doxycycline (DOC), and chlortetracycline (CTC) by static quenching and the inner filter effect . Notably, the fluorescent probe exhibited a good linear relationship with the TC, DOC, and CTC at 0–50, 0–50, and 0–45 μM, respectively, with limits of detection of 0.025, 0.033, and 0.027 μM, respectively. This probe could be employed to detect TC antibiotics in honey and milk, suggesting that it had the great potential for applications in environmental monitoring and food safety.
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BRAIN RESEARCH
·
2023
·
IF 2.9
Yu Chen,Yimeng Zhang,Wei Lin,Ying Tang,Liang Chen,Ying Gao,Guangcheng Gao,Xin Luo,Aiqin Chen,Chun Lin
Chronic postsurgical pain (CPSP) and its emotional comorbidities poses health burden to patients who have received the surgical treatment. However, its underlying mechanism remains unclear. Emerging studies indicate that magnesium deficiency is associated with neurological diseases, and magnesium supplement confers protection under these disease conditions. In this study, we examined the role and mechanism of magnesium deficiency in the pathology of surgery-induced allodynia and negative emotion using a rat model of skin/muscle incision and retraction (SMIR) and investigated the therapeutic effects of magnesium supplementation by oral magnesium-L-Threonate (L-TAMS) in SMIR-injured rats. In the SMIR model, rats developed mechanical allodynia and anxiodepressive-like behaviors. Further, SMIR caused microglia and astrocyte activation and enhanced expression of pro-inflammatory cytokine (TNF-α, IL-1β and IL-6) in the anterior cingulate cortex (ACC). Importantly, magnesium ion (Mg 2+ ) levels decreased in the serum and cerebrospinal fluid (CSF) of SMIR-injured rats, which exhibited high correlation with pain and emotion behavioral phenotypes in these rats. Repeated oral administration of L-TAMS increased serum and CSF levels of Mg 2+ in SMIR-injured rats. Notably, L-TAMS administration reversed SMIR-induced mechanical allodynia and anxiodepressive-like behaviors but did not affect pain and emotional behaviors in sham rats. Moreover, L-TAMS administration suppressed SMIR-caused glial activation and proinflammatory cytokine expression in the ACC but had no such effect in sham rats. Together, our study demonstrates the contributing role of magnesium deficiency in the pathology of surgery-induced chronic pain and negative emotion. Moreover, we suggest that L-TAMS might be a novel approach to treat CPSP and its emotional comorbidities.
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SEPARATION AND PURIFICATION TECHNOLOGY
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2023
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IF 8.6
Shiyang Li,Longdou Tu,Yeqiang Lu,Mingjie Lin,Junmei Ma,Chaojie Bai,Congjie Gao,Lixin Xue
A novel strategy was developed to build high-performance thin film composite (TFC) total heat exchange membranes (THEMs) by in situ growing ZIF-8 crystalline micro-leaves (ZIF-L) from Polyethyleneimine (PEI) coated on polysulfone (PSF) ultra-filtration substrates. It was found that flexible PEI polymeric chains could tightly cross-link and seal large masses of ZIF-L micro-leaves (ZIF/PEI wt. ratio up to 18.5) to thwart CO 2 permeation, on top of PSF substrate. Such PEI cross-linking could also effectively open up the internal channels of ZIF-L micro-leaves to enhance moisture permeance and latent heat recovery without trading off CO 2 gas barring property. ZIF-L in varied shapes protruded into the air stream could provide ultra-rough surfaces with increased surface area for improved total energy recovery efficiency. Optimized PEI/ZIF-L TFC THEMs showed ultra-low CO 2 permeance of 0.5–8 GPU and ultra-high total heat recovery rates of 68–74%.
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FOOD CHEMISTRY
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2023
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IF 8.8
Tianle Wu,Peng Wang,Yuyu Zhang,Ping Zhan,Yu Zhao,Honglei Tian,Wanying He
Mutton possesses a typical flavor, known as “muttony” or “goaty”, which significantly limits consumers’ acceptability and its further popularization. Generally, this unpleasant flavor originates from mutton tallow. Thus, we first characterized the key volatiles of the cooked mutton tallow (CMT) via gas chromatography-mass spectrometry/olfactometry (GC–MS/O) and odor activity value (OAV). Combined with aroma recombination and omission tests, eleven compounds, involving 4-methyloctanoic acid, 4-methynonanoic acid, octanoic acid, decanoic acid, hexanal, heptanal, ( E )-2-octenal, ( E )-2-nonenal, ( E )-2-decenal, 2-nonanone and 2-penty-furan, were screened out to be responsible for the “muttony” flavor. The objective of this study was to investigate the sensory property and acceptability of CMTs, elaborated with 4 different levels of thyme phenolic extract (TPE), through descriptive sensory analysis and key muttony-related compounds identification. The results showed that, of different TPEs employed, CMT plus TPE3 was the most effective strategy to control the key “muttony” contributors, thereby to improve flavor profile of CMT.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2023
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IF 8.2
Peng Zhu,Han Yin,Jiajiao Wei,Jianmeng Wu,Dehai Ping,Xingqun Zhang
Capparis spinosa L. (CSL) is used in traditional medicinal purposes for wound dressing because it contains natural phenolic and flavonoid active compounds. In the current study, a bilayer of biocompatible and mechanically stable nanofiber scaffolds with polycaprolactone (PCL)/zinc oxide and Capparis spinosa L. ethyl acetate extract (CSLE)/polylactic acid (PLA) layers was successfully prepared by an electrostatic spinning technique. Microstructural observations carried out by scanning electron microscopy (SEM) have shown that the nanofibers with a smooth surface are continuous and bead-free, and that the size distribution is uniform, with an average diameter of 314.15 nm. The results of careful observation further suggested that polymers in the nanofibers have excellent compatibility with drugs. The results of Fourier transform infrared (FTIR) spectroscopy suggested that CSLE and zinc oxide nanoparticles (ZnO) were successfully loaded in the nanofiber membranes. Water contact angle measurements revealed that the bilayer nanofiber membranes exhibited satisfactory wettability (outside layer, 130°; inner layer, 72.4°). Tensile testing showed that the bilayer PCL/ZnO-CSLE/PLA nanofibers remained unbroken until reaching 10.69 MPa, which is much higher than the tensile strengths of the individual layers or the individual components. Moreover, agar disk diffusion assessment confirmed that the bilayer nanofiber membranes obviously hindered bacterial growth. Cytotoxicity studies showed that the bilayer nanofiber membranes effectively accelerated cell proliferation . The investigated PCL/ZnO-CSLE/PLA bilayer nanofibers have potential for use as membranes for wound dressing applications.
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International Journal of Electrochemical Science
·
2023
·
IF 1.5
Ziwei Wang,Rui An,Yuxuan Dai,Hongxia Luo
In this work, carbon dots (CDs) were produced by one-step ultrasound technology with glucose as the precursor. The effective synthesis of CDs was characterized by Raman spectroscopy and UV-visible spectra. The as-prepared CDs were fixed on a glassy carbon electrode (GCE) via electrochemical deposition to fabricate CDs/GCE, which simultaneously detected dopamine (DA), uric acid (UA), L-tryptophan (Trp) and theophylline (TP). With the differential pulse voltammetry technique, the oxidation peak currents of these four biomolecules were significantly enhanced on CDs/GCE compared to those on bare GCE. The potential differences of DA-UA, UA-Trp, and Trp-TP were computed as 145 mV, 381 mV, and 323 mV, respectively. The broad linear ranges were 0.5-50 μM for DA, 3-75 μM for UA, 1-65 μM for Trp and 10-200 μM for TP with limits of detection (LODs) of 0.007 μM, 0.011 μM, 0.11 μM and 0.33 μM (S/N = 3), respectively. The CD/GCE sensor had good stability and strong anti-interference ability and was applicable to detecting actual samples.
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Plants-Basel
·
2023
·Vol. 12
·期 6
·1414
·
IF 4.5
Xiaoyun Huang,Chengwu Fan,Dongyi Xie,Hongxing Chen,Song Zhang,Hui Chen,Song Qin,Tianling Fu,Tengbing He,Zhenran Gao
To study the synergistic effects of water management and silicon (Si) foliar spraying on the uptake and transport of cadmium (Cd) in rice, we designed four treatments: conventional intermittent flooding + no Si foliar spraying (CK), continuous flooding throughout the growth stage + no Si foliar spraying (W), conventional intermittent flooding + Si foliar spraying (Si) and continuous flooding throughout the growth stage + Si foliar spraying (WSi). The results show that WSi treatment reduced the uptake and translocation of Cd by rice and significantly reduced the brown rice Cd content, with no effect on rice yield. Compared with CK, the Si treatment increased the net photosynthetic rate (Pn), stomatal conductance (Gs) and transpiration rate (Tr) of rice by 6.5–9.4%, 10.0–16.6% and 2.1–16.8%, respectively. The W treatment decreased these parameters by 20.5–27.9%, 8.6–26.8% and 13.3–23.3%, respectively, and the WSi treatment decreased them by 13.1–21.2%, 3.7–22.3% and 2.2–13.7%, respectively. The superoxide dismutase (SOD) and peroxidase (POD) activity decreased by 6.7–20.6% and 6.5–9.5%, respectively, following the W treatment. Following the Si treatment, SOD and POD activity increased by 10.2–41.1% and 9.3–25.1%, respectively, and following the WSi treatment, they increased by 6.5–18.1% and 2.6–22.4%, respectively. Si foliar spraying ameliorated the detrimental effects of continuous flooding throughout the growth stage on photosynthesis and antioxidant enzyme activity. We conclude that synergistic continuous flooding throughout the growth stage, combined with Si foliar spraying, can significantly block Cd uptake and translocation and is therefore an effective means of reducing the accumulation of Cd in brown rice.Keywords:water management;foliar spraying;Si;cadmium;photosynthesis
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Frontiers in Pharmacology
·
2019
·
IF 3.845
Li Wei,He Weiming,Xia Ping,Sun Wei,Shi Ming,Zhou Yao,Zhu Weiwei,Zhang Lu,Liu Buhui,Zhu Jingjing,Zhu Yiye,Zhou Enchao,Sun Minjie,Gao Kun
Abelmoschus manihot (L.) Medik. (Malvaceae) is a herb used in traditional Chinese medicine to treat some kidney diseases. To date, the detailed mechanisms by which A. manihot improves some kinds of renal disease are not fully understood. In this study, we established Adriamycin-induced NRK-52E cells, the normal rat kidney epithelial cell line, injury, and Sprague-Dawley rats with Adriamycin-induced nephropathy to evaluate the role and mechanisms of total extracts of A. manihot flower (TEA) both in vitro and in vivo. We found that TEA ameliorated Adriamycin-induced cellular morphological changes, cell viability, and apoptosis through the suppression of protein oxidation and ERK1/2 signaling. However, this anti-oxidative stress role of TEA was independent of ROS inhibition. Adriamycin activated ERK1/2 signaling followed by activation of NLRP3 inflammasomes. TEA suppressed NLRP3 inflammasomes via inhibition of ERK1/2 signal transduction; decreased proteinuria and attenuated renal tubule lesions; and inhibited the expression of NLRP3 in tubules in rats with Adriamycin nephropathy. Collectively, TEA protects renal tubular cells against Adriamycin-induced tubule injury via inhibition of ROS-ERK1/2-NLRP3 inflammasomes.
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JOURNAL OF CEREAL SCIENCE
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2019
·
IF 2.452
Qi-Ji Shan,Jian-Hua Liu,Wu Li,Hong Wang,Xiao-Dan Hu,Tong Li,Jian-Guang Hu,Xin-Bo Guo,Rui Hai Liu
Waxy maize presents a series of changes during kernel development. In this study, contents and gene expression profiles of folate and vitamin C during kernel development of waxy maize were explored. Six inbreds, three colors of kernels, four developing periods and two planting seasons in the same experimental fields were analyzed. We found that contents of folate and vitamin C declined overall through four development periods in both seasons, while the manners of gene expression varied, responding to different weather conditions. Key genes in synthetic pathways of folate and vitamin C corresponded to the variation of their contents. GTP cyclohydrolase ( GTPCH ) played an important role in the biosynthesis of folate and vitamin C during kernel development. Another key gene, dehydroascorbate reductase ( DHAR ), was associated with the dynamic balance of vitamin C pool in responding to weather. Considering the contents and gene expression of folate and vitamin C, results indicated that appropriate conditions (temperature, humidity, rainfall and radiation) could facilitate the kernel development of waxy maize. Furthermore, coordinate regulation might happen between the biosynthesis of folate and vitamin C. This study promoted a better understanding of the reason for choosing kernels from mid-late period of development in waxy maize harvest.
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Journal of Functional Foods
·
2019
·
IF 3.197
Yanfang Yu,Bing Zhang,Yuhui Xia,Hongyan Li,Xuping Shi,Junwen Wang,Zeyuan Deng
The changes of phenolic compounds from the freeze-dried, hot-air dried, roasted and steamed mulberry ( Morus alba L.) leaves during the in vitro digestion were investigated. Caffeoylquinic acids, quercitrin glycosides and kaempferol glycosides were the main compounds. After simulated gastrointestinal digestion, the bioaccessibility of phenolics was much higher in roasted samples than those in hot-air, dried and steamed samples. Approximately 50%–80% of the bioaccessible phenolics were dialyzable depending on the different processing methods. The freeze-dried samples contributed to the highest amount of bioaccessible phenolics, followed by hot-air dried and roasted ones. All the initial phenolics degraded rapidly and were not detected after 24 h of faecal fermentation, except that at 0.5 h the amount of isoquercitrin and astragalin were increased by 156.48% and 177.44%, respectively. Consequently, quercetin, kaempferol, dihydrocaffeic acid, 3-(4-hydroxyphenyl) propionic acid and 3-methoxyphenyl-acetic acid were formed at different time. Transformation pathways for phenolics in the faecal fermentation were proposed.
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Frontiers in Microbiology
·
2018
·
IF 4.019
Lu Qinhua,Wang Yuchun,Li Nana,Ni Dejiang,Yang Yajun,Wang Xinchao
Colletotrichum, the causative agent of anthracnose, is an important pathogen that invades the tea plant (Camellia sinensis). In this study, 38 isolates were obtained from the diseased leaves of tea plants collected in different areas of Zhejiang Province, China. A combination of multigene (ITS, ACT, GAPDH, TUB2, CAL, and GS) and morphology analyses showed that the 38 strains belonged to two different species, namely, C. camelliae (CC), and C. fructicola (CF). Pathogenicity tests revealed that CC was more invasive than CF. In vitro inoculation experiments demonstrated that CC formed acervuli at 72 hpi and developed appressoria on wound edges, but CF did not develop these structures. Under treatment with catechins and caffeine, the growth inhibition rates of CF were remarkably higher than those of CC, indicating that the nonpathogenic species CF was more vulnerable to catechins and caffeine. Growth condition testing indicated that CF grew at a wide temperature range of 15–35°C and that the optimum temperature for CC growth was 25°C. Growth of both CC and CF did not differ between acidic and weakly alkaline environments (pH 5–8), but the growth of CC was significantly reduced at pH values of 9 and 10. Furthermore, the PacC/RIM101 gene, which associated with pathogenicity, was identified from CC and CF genomes, and its expression was suppressed in the hyphae of both species under pH value of 5 and 10, and much lower expression level was detected in CC than that in CF at pH 6. These results indicated that temperature has more important effect than pH for the growth of two Colletotrichum species. In conclusion, the inhibition by secondary metabolite is an important reason why the pathogenicity by CC and CF are different to tea plant, although the environmental factors including pH and temperature effect the growth of two Colletotrichum species.
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Food & Function
·
2018
·Vol. 10
·期 1
·266-276
·
IF 3.289
Xiao-Qian Fu,Gen-Lin Zhang,Long Deng,Yan-Yan Dang
Enzyme-assisted aqueous two-phase extraction (EA-ATPE) using ethanol/ammonium sulfate system was investigated for total polyphenol (TP) and lutein from marigold flowers. The important factors were investigated by single factor experiment and response surface methodology combined with Box–Behnken design to optimize the operating parameters of EA-ATPE. The maximum yields of TP and lutein were 83.56 ± 0.69 mg g−1 and 5.59 ± 0.13 mg g−1, respectively. Compared with aqueous two-phase extraction and Soxhlet extraction (SE), the extraction yield of TP by EA-ATPE is 64.91% higher and the extract of EA-ATPE has better antioxidant activity. The pretreatment effect was also researched by scanning electron microscopy. Thus, EA-ATPE is an efficient method for extracting bioactive components from plants.
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