FOOD CHEMISTRY
·
2026
·
IF 10.4
Zineb Ould Yahia,Lianghua Xie,Ahmed K. Rashwan,Bolai Paul,Wei Chen
Cyanidin-3- O -glucoside (C3G), a promising flavonoid with diverse biological properties, faces challenges in functional food application due to instability under various conditions. Therefore, this study aimed to develop a novel gum Arabic-coated nano-nutriosome (GA-C3G-NU) for promoting gastro-intestinal (GI) delivery of C3G and fortification of set-type yogurt (Ygr). The GI digestion study revealed that GA improved the stability of C3G-NU. After freeze-drying, FZD GA-C3G-NU maintained their nanosized, exhibited high encapsulation efficiency ≥90%, and an acceptable PDI ≤0.30. SEM analysis revealed crystal-like structure in GA-C3G-NU, while the XRD study confirmed their decreased crystallinity. Furthermore, the FZD GA-C3G-NU showed significantly controlled release profile ( p < 0.05) of C3G. The GA-C3G-NU didn't negatively affect the yogurt's properties. It maintained the desirable acidity while enhancing water holding capacity, color, texture, microstructure, and compatibility with lactic acid bacteria. Overall, GA-C3G-NU could be a promising carrier for enhancing C3G's gastrointestinal delivery, with potential use in dairy products.
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Journal of Materials Chemistry C
·
2026
·
IF 5.1
Yuanhao Chen,Xiaoshan Zhang,Yirong Liu,Haisheng Liu,Dechao Yu,Dawei Zhang
Gadolinium gallium garnet has been emerging as a starlet for preparing efficient luminescent materials, while via crystal field engineering the luminescence properties of rare-earth activator in its solid solution phosphors were scarcely explored. In this work, Er 3+ -doped Gd 3 Zn x Ga 5-2x Ge x O 12 (GZG 5- 2x G:Er 3+ ) solid solutions were prepared by high-temperature solid-state reaction, where a hetero-valent co-substitution strategy was implemented via introducing Zn 2+ /Ge 4+ pair to replace 2 Ga 3+ sites. X-ray diffraction Rietveld refinements confirm all samples crystallized into pure garnet phase. Upon 381 nm excitation, Er 3+ concentration was spectrally optimized to be about 10%, substituting the Gd 3+ sites, and via the Zn 2+ /Ge 4+ co-substitution, luminescence intensity of GZG 2 G:10%Er 3+ increases by more than 3 times in comparison with that of the baseline GZGG:10%Er 3+ sample. All the GZG 5-2x G:10%Er 3+ solid solution samples color in bright green under illumination using an ultraviolet ~ 365 nm lamp.Thermometric properties of Er 3+ 2 H 11/2 -4 S 3/2 thermally coupled levels of were systematically studied on basis of fluorescence intensity ratio principle. The GZG 5-2x G:10%Er 3+ all can perform temperature sensing over a wide temperature range of 298-573 K with a maximum relative sensitivity (S r ) above 1.20% K -1 and an applicable minimum temperature resolution (δT) around 0.4 K. Continuous exploration of solid solution-manipulating luminescent properties would develop novel thermometry probes (particularly for activator with spin-allowed transitions) with higher S r and smaller δT for practical optical temperature sensing.
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PROGRESS IN SOLID STATE CHEMISTRY
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2026
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IF 9.7
Chao Wei,Jingyu Ran,Jie Zhang
The wideband near-infrared (NIR) phosphors for next-generation intelligent NIR light sources are becoming a research hotspot in the field of luminescent materials due to their potential applications in optical sensing, biological imaging, and smart lighting. This study reports a Cr 3+ -activated A 3 B(PO 4 ) 3 -type (Sr 3 Lu(PO 4 ) 3 ), abbreviated as SLP) near-infrared phosphor. Under 466 nm blue light excitation, SLP:Cr 3+ phosphor exhibits a broad near-infrared emission from 700 to 1200 nm with a peak wavelength at 860 nm, a full width at half maximum (FWHM) of 141 nm, and an initial quantum yield of 31.48%. Structural and spectroscopic characterization confirms that Cr 3+ preferentially occupies the octahedral coordination sites of Lu 3+ in the matrix, forming a weak crystal field environment that favors the spin-allowed 4 T 2 → 4 A 2 transition of Cr 3+ , leading to broad near-infrared emission. Additionally, by substituting Y 3+ for the B-site (Lu 3+ site), the luminescent intensity of the material is significantly enhanced, and the quantum yield is increased to 81.53%. Furthermore, the introduction of Yb 3+ constructs a Cr 3+ →Yb 3+ energy transfer system, further optimizing the luminescent performance. Although the phosphor exhibits severe thermal quenching, the packaged near-infrared phosphor-converted light-emitting diodes (NIR pc-LEDs) maintain a low surface temperature of 59.5 °C at 500 mA, ensuring reliable operation. The phosphor also exhibits excellent temperature sensitivity (max relative sensitivity: 3.33%·K −1 ) for fluorescence thermometry. Practical applications including invisible QR code encryption, night vision, biological imaging, and long-distance illumination are demonstrated, showcasing the versatility of the developed NIR pc-LED. This work provides a high-performance NIR phosphor candidate for multi-functional smart light sources.
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DALTON TRANSACTIONS
·
2026
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IF 3.3
Hussin Elkik,Muhammad Mujahid Iqbal,Aqsa Munawar,Zhihua Yang,Fangfang Zhang,Shilie Pan
The development of robust strategies for designing high-performance ultraviolet (UV) birefringent materials has become a critical challenge. The combination of alkali metal and Ca2+ cations, which do not exhibit d–d or f–f transitions, with [NO3]− anions that possess high polarizability anisotropy results in the synthesis of three hydrated alkali metal calcium nitrates, ACa(NO3)3·2H2O (A = NH4, Rb, Cs). The title compounds were synthesized at room temperature using the water solution–evaporation technique, featuring a unique chain-like structure composed of [CaO9] polyhedra and [NO3]− units. The compounds exhibit notable optical properties, including short UV absorption edges (220–235 nm) and moderate birefringence (0.077–0.086 at 546 nm). Detailed structural investigation and theoretical analyses reveal that the birefringence is primarily due to the planar triangular arrangement of the [NO3]− groups. This research not only increases the structural diversity within inorganic materials but also provides a key approach for further studies of all-inorganic birefringent optical materials in the UV region.
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EUROPEAN JOURNAL OF PHARMACOLOGY
·
2026
·
IF 5.7
Pingting Wu,Weilai Chen,Jie Li,Jiayi Xing,Haote Wu,Jingyang Tong,Ping Chen,Haibin Tong,Yongping Chen,Chenwei Pan
Acetaminophen (APAP) overdose causes acute liver injury (ALI) by triggering regulated hepatocyte death. While Imperata cylindrica (Imperatae Rhizoma) (IR) is used in traditional medicine for its hepatoprotective effects, its active compounds and their capacity to modulate this pyroptotic switch remain unknown. In the present study, friedelin (FRI) and 6-methoxyflavone (6-METH) were identified as the principal active compounds of IR, and their protective effects against APAP-induced ALI were evaluated in vivo and in vitro. The results showed that both FRI and 6-METH significantly ameliorated APAP-induced liver injury and reduced hepatocyte death. Mechanistically, their hepatoprotective effects were associated with AKT1-dependent activation of the PI3K/AKT pathway, accompanied by suppression of Caspase-3/ Gasdermin E (GSDME) signaling and attenuation of apoptosis and pyroptosis. Moreover, pharmacological inhibition or genetic silencing of AKT1 markedly weakened these protective effects. Taken together, these findings suggest that FRI and 6-METH are major hepatoprotective constituents of IR and that modulation of the AKT1-mediated Caspase-3/GSDME pathway may contribute to their protective actions against APAP-induced ALI. These findings validate its active compounds as promising therapeutic leads for ALI.
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SENSORS AND ACTUATORS A-PHYSICAL
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2026
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IF 5.1
Jing-Wen Liu,Yan Li,Gang-Long Song,Xiao-Xue Lian
Listeria monocytogenes is a life-threatening foodborne pathogen, and indirect detection via its specific metabolite 3-hydroxy-2-butanone has emerged as a validated strategy. However, reliable early monitoring of LM requires rapid response kinetics for real-time analysis and high selectivity against food-derived volatile organics, and achieving both simultaneously at the ppb level remains a significant challenge. Herein, we have synthesized Fe-doped ZnO nanofibers and the introduction of Fe induces the formation of a mixed Fe 2 + /Fe 3+ valence that facilitates dynamic redox cycling, thereby enhancing charge transfer efficiency and creating additional active sites to improve gas-sensing performance. Systematic gas-sensing evaluations showed that the 0.5% Fe-doped ZnO sensor exhibits an optimal response of 168.9–100 ppm 3H-2B at 170 °C, with a rapid response time of 2 s and a low detection of 110 ppb, significantly outperforming the undoped ZnO and higher Fe-doped counterparts. X-ray photoelectron spectroscopy confirmed the coexistence of Fe 2+ /Fe 3+ , whose dynamic redox cycles enhanced electron exchange between the nanofibers and 3H-2B, thereby boosting sensing performance. This study offers an economical method for 3H-2B detection and demonstrates variable-valence Fe is a potential dopant to tailor ZnO-based gas sensors toward food safety and environmental applications.
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Journal of Agriculture and Food Research
·
2026
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IF 7.2
Rongting Min,Aji Li,Houxier Li,Li Yang,Nan Zhang,Jiahui Wu,Xiang Wang,Lei Li,Maochun Xiao,Shiyao Su,Mengling Yang,Jingmei Wang,Zhiqiu Yang,Miaomiao Chang,Xueyong Wang
Salvianolic acid B (SA) has significant regulatory effects on glucolipid metabolism. Combining SA with resistant starch endowed this type of starch with unique functional properties. This study represents the first direct complexation between SA and Canna edulis type 3 resistant starch (RS3). The findings indicated that SA has a beneficial effect on the physicochemical and prebiotic properties of RS3. SA and RS3 form a complex via non-covalent interactions, thereby increasing the crystalline and gelatinization temperatures. The 1 H NMR spectrum exhibited aromatic ring signals and increased hydroxyl signal intensity. Concurrently, the solubility of SA-RS3 decreased after composite formation, while the expansion, water absorption index and resistant starch content (59.40%) increased markedly. Fermentation analysis revealed decreases in pH and increases in reducing sugar content, in vitro antioxidant activity and hypoglycemic activity. Interestingly, SA-RS3 substantially increased the relative abundance of the Firmicutes and Actinomycetes phyla, promoted the proliferation of the beneficial bacterium Bifidobacterium , inhibited the growth of Klebsiella and Sutterella , and increased the content of acetic, propionic, and butyric acids. This indicates that SA confers antioxidant properties while retaining the prebiotic properties of raw RS3. Consequently, SA-RS3 demonstrates potential for blood glucose regulation and exhibits in vitro prebiotic properties, offering a novel direction for the development of RS3-type functional foods.
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SENSORS AND ACTUATORS B-CHEMICAL
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2026
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IF 8.3
Shixin Ma,Zhihua Zhao,Chen Chen,Zhuo Chen
1-Octen-3-ol is a characteristic volatile organic compound released from moldy wheat. Therefore, the development of high-performance gas sensors for 1-octen-3-ol detection is of great significance for ensuring grain safety by enabling real-time monitoring of wheat quality. However, substantial challenges remain, including poor selectivity and insufficient stability. To address these limitations, this study designed and successfully synthesized a three-dimensional nest-like Tungsten trioxide (WO 3 ) structure decorated with FeCo nanoalloys. By modulating the loading amount of the iron (Fe) cobalt (Co) alloy, we achieved precise tuning of surface oxygen vacancies and facilitated efficient electron transfer within the nanocomposite, resulting in a significantly enhanced gas response. The optimized 1.5FeCo@WO 3 sensor exhibited a high response value of 12.68 toward 100 ppm 1-octen-3-ol, along with superior selectivity and excellent long-term stability. Systematic material characterizations, including scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and Brunauer-Emmett-Teller (BET) analyses, confirmed that the composite possesses a high specific surface area, abundant oxygen vacancies, and a robust interfacial electronic interaction between the FeCo alloy and the WO 3 matrix. Furthermore, density functional theory calculations were integrated into the mechanistic analysis. Consequently, this work yields a promising sensor candidate for the early warning of wheat diseases and proposes a material design strategy for developing economical, high-sensitivity gas sensors for agricultural applications.
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Journal of Materials Chemistry A
·
2026
·
IF 9.2
Tianqing Miao,Hongjiao Wang,Cancan Li,Deyu Bao,Yujin Li,Shenwei Wu,Junhuai Wang,Yidi Zhou,Chenfang Sun,Xiao Li
Organic thin-film transistors (OTFTs) hold immense potential for ultrasensitive gas detection; however, their performance is fundamentally constrained by the trade-off between carrier mobility and analyte permeability. Herein, we resolve this dichotomy by engineering a long-range ordered P3HT nanowire percolation network via a kinetically controlled solvent-concentration-temperature ternary modulation strategy. This approach effectively enhances nanowire network continuity, thereby enabling efficient charge transport while preserving analyte-accessible diffusion pathways. Consequently, the optimized device achieves a six-fold enhancement in mobility and an exceptional ammonia (NH3) detection limit of 238 ppb, attributed to the unimpeded diffusion of analytes to the buried channel interface. Furthermore, to transcend the intrinsic non-linearity of physical adsorption kinetics, we integrate a gradient boosting regression algorithm, creating a "sensor-algorithm" initial proof-of-concept that enables precise, linearized quantitative analysis. This work provides a fundamental design principle for structuring soft electronic materials and demonstrates a versatile platform for low-power, intelligent environmental and health sensing applications.
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CELL BIOLOGY AND TOXICOLOGY
·
2026
·Vol. 42
·期 1
·68
·
IF 5.7
Li Ting,Feng Mengxiao,Wang Ping,Jiang Miao,Cui Jaiyu,Jin Mengxia,Song Congying,Lin Liying,Lu Yuan-Qiang
Baicalein, a naturally occurring flavonoid with well-documented anti-inflammatory and neuroprotective effects, has shown therapeutic promise in multiple models of neurological disorders. However, whether baicalein can counteract diquat-induced neurotoxicity remains uncertain. This study reveals that baicalein alleviates diquat-induced neuroinflammation and microglial pyroptosis in mice in a gut microbiota (GM)-dependent manner. In the in vivo experiments, multi-omics analyses demonstrated that baicalein elevates the GM-derived metabolite indole-3-propionic acid (IPA), which was sufficient to suppress pyroptosis. In parallel, IPA was identified as a critical mediator of baicalein's neuroprotective effects, as exogenous IPA administration recapitulated baicalein's protection, and baicalein treatment significantly elevated IPA levels. Mechanistically, through inhibiting the DEAD-box helicase 3 X-linked / GTPase-activating protein (SH3 domain) binding protein 1 pathway by in vitro experiments. Our study demonstrated that baicalein mitigates diquat-induced neuroinflammation, underscoring the therapeutic potential of targeting the GM to counteract herbicide-related neurotoxicity. Graphical
The alternative text for this image may have been generated using AI.
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METALLURGICAL AND MATERIALS TRANSACTIONS B-PROCESS METALLURGY AND MATERIALS PROCESSING SCIENCE
·
2026
·
IF 3.3
Yu Wanquan,Zhang Run,Wang Yujian,Liu Mengxia,Su Jichang,Lv Xuewei,Dang Jie
The high cost of conventional titanium feedstocks has severely constrained the industrial application of Ti–Al-based MAX-phase composites. This work presents a clean, cost-effective pathway for synthesizing Ti 4 Al(C, N) 3 /Al 2 O 3 composites directly from natural ilmenite concentrate. The synthesis encompasses two sequential stages: (i) the reduction and carbonitridation of pre-oxidized ilmenite in a hydrogen-rich atmosphere to yield a Ti(C, N, O) precursor, and (ii) pressureless sintering of the precursor with Al and Ti powders, followed by acid leaching to remove intermetallic byproducts. Through systematic parametric optimization, the precursor synthesis was established at 1150 °C for 70 min in a 4 vol pct CH 4 –80 vol pct H 2 –16 vol pct N 2 atmosphere, achieving a carbonitridation ratio exceeding 90 pct while suppressing detrimental carbon deposition. Subsequent pressureless sintering at 1500 °C for 4 h with a molar ratio of 2.2Ti(C, N, O):2Al:1Ti yielded the target composite. Mechanistic investigation, combining experimental characterization and density functional theory (DFT) calculations, reveals that the Al 3 Ti intermediate phase plays a dual critical role: it promotes deep deoxygenation of Ti(C, N, O) with in situ formation of Al 2 O 3 reinforcements, while simultaneously healing N vacancies in the MAX-phase lattice. Aberration-corrected transmission electron microscopy (AC-TEM) confirmed that the synthesized Ti 4 Al(C, N) 3 solid solution possesses a pristine hexagonal structure identical to that of phase-pure Ti 4 AlN 3 , with no observable lattice distortion or extended defects. This work presents a novel strategy for the economical and sustainable synthesis of high-performance Ti 4 Al(C, N) 3 /Al 2 O 3 composites.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2025
·
IF 5.4
Bingxian Niu,Yuxia Wang,Yu Han,Pan Zhang,Yonghong Cai,Yufeng Wu,Linlin Zhao,Ying Xu
This paper presents the synthesis of a novel polyaspartate derivative (PASP-BBA) with both corrosion inhibition and antibacterial properties. The compound is synthesised using polysuccinimide (PSI), 1,4-bis(3-aminopropyl)piperazine (BAPP) and bromoacetic acid (BA) as raw materials. By controlling the degree of polymerisation, a BAPP grafting rate of 55 % is achieved. The corrosion inhibition performance of PASP-BBA was evaluated using electrochemical methods and weight loss method. The potentiodynamic polarization results indicated that at a concentration of 70 mg/L, the corrosion inhibition efficiency of PASP-BBA was 54.28 %, which was 33.53 % higher than that of PASP. The study on the corrosion inhibition mechanism of PASP-BBA through quantum chemical calculations showed that PASP-BBA achieved this effect through physical and chemical adsorption, adhering to the surface of carbon steel and reducing the contact with corrosive media. The antibacterial performance was evaluated using filter paper method and dilution plating method. The research results indicated that PASP-BBA has selective antibacterial effects and can effectively inhibit Escherichia coli . When the concentration of PASP-BBA was 100 mg/mL, the survival rate of Escherichia coli dropped to 21 %. Meanwhile, Bacillus cereus could survive, thereby enhancing the dual functions of polyaspartic acid derivatives in corrosion inhibition and antibacterial applications. This study provides certain theoretical references for the design of green multifunctional water treatment agents.
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