JOURNAL OF NANOBIOTECHNOLOGY
·
2021
·Vol. 19
·期 1
·1-13
·
IF 10.435
Chen Tong,Chu Qiang,Li Mengyang,Han Gaorong,Li Xiang
Electrodynamic therapy (EDT) has recently emerged as a potential external field responsive approach for tumor treatment. While it presents a number of clear superiorities, EDT inherits the intrinsic challenges of current reactive oxygen species (ROS) based therapeutic treatments owing to the complex tumor microenvironment, including glutathione (GSH) overexpression, acidity and others. Herein for the first time, iron oxide nanoparticles are decorated using platinum nanocrystals (Fe 3 O 4 @Pt NPs) to integrate the current EDT with chemodynamic phenomenon and GSH depletion. Fe 3 O 4 @Pt NPs can effectively induce ROS generation based on the catalytic reaction on the surface of Pt nanoparticles triggered by electric field (E), and meanwhile it may catalyze intracellular H 2 O 2 into ROS via Fenton reaction. In addition, Fe 3+ ions released from Fe 3 O 4 @Pt NPs under the acidic condition in tumor cells consume GSH in a rapid fashion, inhibiting ROS clearance to enhance its antitumor efficacy. As a result, considerable in vitro and in vivo tumor inhibition phenomena are observed. This study has demonstrated an alternative concept of combinational therapeutic modality with superior efficacy.
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高影响因子
CHINESE JOURNAL OF POLYMER SCIENCE
·
2014
·Vol. 32
·期 10
·1413-1418
·
IF 1.42
Li Hua-jie,Yu Zhong,Wang Shuang-ping,Zhang Li-ming,Yang Li-qun
Photosensitizer (photosan)-encapsulated micelles were prepared by self-assembly of Photosan with two amphiphilic polysaccharide derivatives, including the cholesteryl conjugated sodium alginate derivative (CSAD) and the deoxycholic acid group conjugated chitosan derivative (DA-Chit). The results of UV-Vis and fluorescence spectroscopy indicated that the hydrogen bonding strength dominated the micelle formation. Methyl viologen was used as a model quencher of photosan. Using the steady-state fluorescence technology, the quenching constants were determined to be 2.05, 1.88 and 0.30 L/mmol for the free photosan, the photosan-CSAD micelle and the photosan-DA-Chit micelle, respectively. This suggested that photosan was protected from quenching of methyl viologen by the polysaccharide micelles. In addition, the protection effect of the photosan-DA-Chit micelle was significantly stronger than that of the photosan-CSAD micelle. The photosan-DA-Chit micelle is thus anticipated for protection of photoactivity of photosan during the blood circulation process in vivo .
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高影响因子
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
·
2016
·Vol. 20
·期 7
·2055-2062
·
IF 2.327
Chen Yalin,Mei Tao,Chen Yi,Wang Jianying,Li Jinhua,Fu Yang,Dai Guangchao,Wang Sheng,Xiong Weilai,Wang Xianbao
In this study, we prepared the porphyrin/reduced graphene oxide (porphyrin/RGO) nanocomposite which combined the excellent electrical conductivity and high specific surface area of RGO and the catalytic effect on the oxidation of guanine and adenine of porphyrin for simultaneous detection of guanine and adenine. Since the nanocomposite had remarkable synergistic effect between porphyrin and RGO, the modified glassy carbon electrode (GCE) exhibited excellent electrochemical catalytic activities and high sensitivity toward the detection of guanine and adenine. The nanocomposite was successfully applied to simultaneous quantitative detection of guanine and adenine with a linear range covering 0.05–150 and 0.2–100 μM, respectively, and the detection limits (LOD) ( S / N = 3) were estimated to be 0.016 μM for guanine and 0.06 μM for adenine. The porphyrin/RGO/GCE was applied for simultaneous detection of trace amounts of guanine and adenine in hydrochloric calf thymus DNA. Moreover, the porphyrin/RGO/GCE was simply fabricated and displayed good reproducibility.
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高影响因子
International Journal of Environmental Science and Technology
·
2020
·Vol. 17
·期 9
·4061-4074
·
IF 2.54
Liu H.,Li D.,Shao L.,Wu D.,Zhang H.,Yuan J.,Xu F.
In this study, a crack-free PDMS–SiO 2 –BiPO 4 (P/Si/Bi) composite was prepared via a solgel-assisted route by dispersing pre-prepared bismuth oxybromide into a solution that was composed of hydroxyl-terminated polydimethylsiloxane (PDMS–OH), tetraethyl orthosilicate and phosphoric acid. Analysis via the FTIR, XRD, XPS and SEM–EDX techniques demonstrated that the nonisolated BiPO 4 particles with a monoclinic crystal phase were uniformly distributed on the surface of the P/Si/Bi composite, which can provide more active sites and a larger surface area for photocatalysis compared with other materials. The photocatalytic activity of the P/Si/Bi composite loaded with various mass ratios of BiPO 4 (9 wt%, 12 wt%, 18 wt% and 27 wt%) was investigated via the degradation of methylene blue (MB, 10 mg/L) under UV light irradiation. It was found that the P/Si/Bi composite loaded with 18 wt% BiPO 4 realized the highest degradation efficiency of MB, and its corresponding apparent rate constant was approximately 2.2 times that of the PDMS–SiO 2 –TiO 2 composite (loaded with 18 wt% TiO 2 ). The effects of inorganic ions on the degradation of MB were also investigated. The static contact angle and photocatalytic activity of the P/Si/Bi composite changed minimally after five cyclic experiments, thereby demonstrating its remarkable durability in sustainable applications. In addition, the photogenerated reactive species that were responsible for the degradation of MB within the P/Si/Bi composite were identified, and a photocatalytic mechanism was proposed.
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高影响因子
International Journal of Peptide Research and Therapeutics
·
2019
·Vol. 26
·期 1
·121-128
·
IF 1.219
Wang Mengwei,Lv Mingxiu,Lu Kui,Liu Guangbin,Mai Wenpeng,Yu Bo,Lou Yudan
Six breast cancer susceptibility gene 1 (BRCA1) peptide fragments were designed by removing N-terminal amino acid residues of BRCA1(846–871). Peptide fragments BRCA1(846–871), BRCA1(852–871), BRCA1(854–871), BRCA1(856–871), BRCA1(857–871) and BRCA1(861–871) were obtained by Fmoc solid-phase synthesis, purified by reversed-phase high-performance liquid chromatography and characterized by electrospray ionization mass spectrometry. The interaction between BRCA1 fragment peptides and RAD51(181–200) target peptides were investigated using circular dichroism (CD) spectroscopy, fluorescence spectroscopy, and microscale thermophoresis (MST). The results of CD spectroscopy showed that the secondary structures of RAD51(181–200) were altered after the addition of BRCA1 peptide fragments. The fluorescence results proved that all six BRCA1 peptide fragments BRCA1(846–871), BRCA1(852–871), BRCA1(854–871), BRCA1(856–871), BRCA1(857–871) and BRCA1(861–871) could bind to RAD51(181–200) independently, their quenching processes were static, and the binding constant of peptide fragments with RAD51(181–200) were 4.01 × 10 5 L mol −1 , 7.22 × 10 5 L mol −1 , 7.84 × 10 5 L mol −1 , 1.1 × 10 4 L mol −1 , 6.19 × 10 3 L mol −1 , 6.18 × 10 3 L mol −1 . The results of MST displayed that BRCA1(854–871) could combine with RAD51(181–200), and the dissociation constant K d was 126.44 µM. Compared with other five peptide fragments, the interaction between BRCA1(854–871) and RAD51(181–200) was much stronger.
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高影响因子
RARE METALS
·
2021
·Vol. 40
·期 11
·3195-3204
·
IF 4.003
Lu Zhi-Yu,Yu Hai-Jie,Lu Xiong,Song Meng-Chen,Wu Fu-Ying,Zheng Jia-Guang,Yuan Zhi-Fei,Zhang Liu-Ting
Magnesium hydride (MgH 2 ), which possesses high hydrogen density of 7.6 wt%, abundant resource and non-toxicity, has captured intense attention as one of the potential hydrogen storage materials. However, the practical application of Mg/MgH 2 system is suffering from high thermal stability, sluggish absorption and desorption kinetics. Herein, two-dimensional (2D) vanadium nanosheets (V NS ) were successfully prepared via a facile wet chemical ball milling method and proved to be highly effective on improving the hydrogen storage performance of MgH 2 . For instance, the MgH 2 + 7 wt% V NS composite began to release hydrogen at 187.2 °C, 152 °C lower than that of additive-free MgH 2 . At 300 °C, 6.3 wt% hydrogen was released from the MgH 2 + 7 wt% V NS composite within 10 min. In addition, the fully dehydrogenated sample could absorb hydrogen even at room temperature under hydrogen pressure of 3.2 MPa. X-ray diffractometer (XRD) and transmission electron microscopy (TEM) results confirmed metallic vanadium served as catalytic unit for facilitating the de/rehydrogenation reaction of MgH 2 . This finding presents an example of facile synthesis of two-dimensional (2D) vanadium with excellent catalysis, which may shed light on future design and preparation of highly effective layered catalysts for hydrogen storage and other energy-related areas.
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高影响因子
Nature Communications
·
2023
·Vol. 14
·期 1
·1-12
·
IF 16.6
Zhang Jiyu,Yan Yongliang,Wang Xin,Cui Yanyan,Zhang Zhengfeng,Wang Sen,Xie Zhengkun,Yan Pengfei,Chen Weihua
Non-aqueous sodium-ion batteries (SiBs) are a viable electrochemical energy storage system for grid storage. However, the practical development of SiBs is hindered mainly by the sluggish kinetics and interfacial instability of positive-electrode active materials, such as polyanion-type iron-based sulfates, at high voltage. Here, to circumvent these issues, we proposed the multiscale interface engineering of Na 2.26 Fe 1.87 (SO 4 ) 3 , where bulk heterostructure and exposed crystal plane were tuned to improve the Na-ion storage performance. Physicochemical characterizations and theoretical calculations suggested that the heterostructure of Na 6 Fe(SO 4 ) 4 phase facilitated ionic kinetics by densifying Na-ion migration channels and lowering energy barriers. The (11-2) plane of Na 2.26 Fe 1.87 (SO 4 ) 3 promoted the adsorption of the electrolyte solution ClO 4 − anions and fluoroethylene carbonate molecules, which formed an inorganic-rich Na-ion conductive interphase at the positive electrode. When tested in combination with a presodiated FeS/carbon-based negative electrode in laboratory- scale single-layer pouch cell configuration, the Na 2.26 Fe 1.87 (SO 4 ) 3 -based positive electrode enables an initial discharge capacity of about 83.9 mAh g −1 , an average cell discharge voltage of 2.35 V and a specific capacity retention of around 97% after 40 cycles at 24 mA g −1 and 25 °C.
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高影响因子
International Journal of Environmental Science and Technology
·
2022
·Vol. 20
·期 6
·6777-6790
·
IF 3.519
Liu H.,Wu S. F.
In situ pore forming achieved by vapor releasing of chemical looping reaction for dynamic compensation of lost pore volume was proposed to improve the durability of the nano-CaO-based adsorbent in calcium looping process. The effect of contents (12–34 wt.%) and kinds of the pore forming agents (MnO 2 , Fe 2 O 3 , Co 2 O 3 , NiO and CuO) on the dynamic pore compensation effect and sorption performance including sorption capacity and durability of the adsorbent was investigated. The results showed that high pore forming capacity could be achieved by high doping content and oxygen mass fraction of agent. Good anti-sintering ability of agent could leads to a prominent pore forming stability. The final dynamic pore compensation effect was controlled by both pore forming capacity and stability. Compared with the nano-CaO/Al 2 O 3 adsorbent, the best dynamic pore compensation effect for the nano-CaO-NiO/Al 2 O 3 adsorbent was achieved with doping NiO content of 21 wt.%, which could increase pore volume by 67.3% after 3 CaL cycles. The total average deactivation rate of the nano-CaO-NiO/Al 2 O 3 adsorbent was reduced by 48%, which meant that in situ dynamic pore compensation could significantly improve the cyclic durability of adsorbents. Graphical abstract
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高影响因子
POLYMER BULLETIN
·
2017
·Vol. 74
·期 9
·3907-3922
·
IF 1.43
Wei Yanyan,Du Xiucai,Ma Xiaoyue,Zhao Kaifeng,Zhang Shiyu,Bai Yapeng
Highly cross-linked polyurethanes based on Diels–Alder (DA) reaction have high hardness but poor toughness. A modified polyurethane with three-furyl diol (TF) was synthesized innovatively to improve its mechanical properties. Three-furyl diol (TF) and hydroxyl terminated polyurethane IDI-TF were synthesized first. Then the reaction of IDI-TF with xylene bismaleimide (BMI) generates cross-linked polyurethane ITB-PU (its soft segment content is 11.5%). Finally, the properties of the polyurethane ITB-PU were characterized by a series of methods. It can be observed that the DA reaction occurred at 50.33 °C, the r-DA reaction at 69.55 °C. When heated at 80 °C for 6 h, the self-healing efficiency of the ITB-PU was 43.91% known from the tensile test, and cracks on it virtually disappeared seen from polarizing microscope (POM). When heat was preserved for 12 h, the self-healing efficiency can reach 80.02%.
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高影响因子
JOURNAL OF SOLUTION CHEMISTRY
·
2013
·Vol. 42
·期 9
·1782-1793
·
IF 1.128
Lu Jia,Li Shu’ni,Zhai Quanguo,Jiang Yucheng,Hu Mancheng
The mean activity coefficients for CsCl in N -methylformamide or urea ( w ) + H 2 O (1 − w ) systems were determined in this work by potentiometry, using ion-selective electrodes at 298.15 K. The value of mass fraction w was varied between 0.00 and 0.40 in five unit-steps and the molality of CsCl was between 0.0020 and 1.4009 mol·kg −1 . The experimental data have been correlated with the Pitzer, modified Pitzer and the extended Debye–Hückel equations. The resulting values of the mean activity coefficients, the osmotic coefficients and the standard Gibbs energy of transfer, together with the Pitzer ion-interaction parameters ( β
(0) , β
(1) and C
φ ), extended Debye–Hückel parameters ( a , c and d ), and modified Pitzer parameters ( b , B
MX , C
MX ) are reported for the investigated systems.
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高影响因子
Science China-Materials
·
2022
·Vol. 66
·期 4
·1460-1470
·
IF 8.64
Cheng Yufei,Sun Qian,Li Qiujie,Zhang Wenwan,Liu Enzhou,Fan Jun,Xie Haijiao,Miao Hui,Hu Xiaoyun
Antimony selenide (Sb 2 Se 3 ) is a narrow-band-gap semiconductor that has been increasingly used as an excellent light-harvesting material in photoelectrocatalysis. The unique connections of the one-dimensional (Sb 4 Se 6 ) n ribbon structural units determine the high anisotropy of their carrier transport. In this study, a reduced graphene oxide (rGO)-modified quasi-one-dimensional Sb 2 Se 3 @In 2 S 3 light-trapping heterostructure was successfully constructed by vapor transport deposition followed by an in situ hydrothermal method. The results showed that the thickness of the in situ grown non-layered In 2 S 3 nanosheets was significantly reduced from 30 to 10 nm under the space-confinement effect of rGO, facilitating the construction of light-trapping nanostructures and increasing the electrochemically active surface area of the photoelectrode. The quasi-one-dimensional Sb 2 Se 3 @In 2 S 3 -rGO nanorod photoelectrode achieved a higher photocurrent density (1.169 mA cm −2 ), which was 2 and 16 times higher than that of Sb 2 Se 3 @In 2 S 3 and pristine Sb 2 Se 3 , respectively. The ultrathin In 2 S 3 nanosheets were co-modified with rGO nanosheets to fabricate a brush-like composite photoelectrode that exhibited favourable stability with an average hydrogen production rate of 16.59 µmol cm −2 h −1 under neutral conditions. The experimental results and theoretical calculations both showed that the significant improvement in photoelectrochemical performance can be perfectly explained by the type-II heterojunction mechanism. This study provides a new exploration to design rGO-modified composite photoelectrodes for photoelectrochemical applications.
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高影响因子
CELLULOSE
·
2022
·Vol. 29
·期 8
·4439-4453
·
IF 6.123
Li Yinan,Li Huixin,Huang Jin,Huang Liulian,Chen Lihui,Ni Yonghao,Zheng Qinghong
A highly transparent ZnO/cellulose composite membrane with UV sensing and shielding abilities was prepared via a facile blending method. ZnO nanoparticles (ZnO NPs) without additional surface modification are uniformly dispersed in the regenerated cellulose (RGC) matrix through the N-methyl-morpholine-N-oxide (NMMO) dissolution of cellulose. Agglomeration of the ZnO NPs is effectively minimized, thanks to the strong hydrogen bonds between ZnO NP and cellulose. The optimized ZnO/RGC membrane exhibits not only high a shielding ratio of 97.67 ± 0.11% for UV lights (< 360 nm) but also high transparency of 87.12±1.55% in the visible light region, which is comparable to traditional plastic products. Benefiting from the high photoelectric performance of ZnO NPs, a UV sensor and a UV blocker were integrated into the same device. The as-fabricated ZnO/RGC membrane, with sensitive UV detecting and effective blocking, as well as the rich availability of cellulose as raw material and its biodegradable nature, is an ideal candidate for high-performance UV detection and protection applications. Graphical abstract
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高影响因子
危险品化学品经营许可证（带存储）