ANALYTICAL SCIENCES
·
2026
·
IF 2
Chen Shi-yao,Lou Yi-Han,Tang Shou-Wan
Coated-type composite chiral stationary phases (CSPs) based on homosubstituted (same substituents introduced onto the glucose unit) and heterosubstituted (different substituents grafted onto the glucose unit) amylose derivatives were prepared and their enantioseparation capabilities in high-performance liquid chromatography were evaluated. Investigations demonstrated that the enantioseparation capabilities of the composite CSPs generally fell in between those of the two single-component CSPs. Notably, several chiral analytes that failed to achieve resolution on the single-component CSPs were successfully discriminated on the composite ones, thereby extending the application scope of an individual amylose derivative-based CSP. Some anomalous retention and selectivity behaviors were also observed on the composite CSPs, which may be due to some interactions between the two polymers during cocoating. Additionally, the impact of mobile phase composition on enantioseparation was examined. In the hexane/2-propanol (80/20, 90/10, and 95/5, v / v ) mobile phase system, a lower 2-propanol content in the mobile phase always results in higher retention factor k 1 , whereas the separation factor α does not change significantly, with the maximum variation of racemate 2 being approximatley 16%. Graphical abstract
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高影响因子
Scientific Reports
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2026
·
IF 4.9
Dong Wenxin,Chen Jie,Qin Chaozhong,Liu Wenhao,Fan Jinyang
A thermo-responsive mineral-based grout composite (GC) was developed for rapid sealing of fracture networks in underground coal pillars, aiming to eliminate oxygen ingress and prevent spontaneous combustion in goaf areas. Coal spontaneous combustion triggered by air leakage poses severe threats to mine safety. Traditional sealants such as rapid-hardening calcium sulfoaluminate (CSA)-sodium silicate systems and polyurethane materials suffer from thermal-runaway risks, poor fire resistance, and complex parameter control requirements. The GC slurry is composed of Mg(OH) 2 , Al(OH) 3 , ultra-fine cement and NIPAM-grafted bentonite. It maintains 200 mm flowability at 20 °C for deep penetration, yet triggers abrupt thickening within 3 min when ≥ 40 °C is encountered, forming a dense oxygen barrier. Adiabatic calorimetry revealed a maximum temperature rise of only 18.4 °C (ΔTmax = 18.4 °C, t max = 7.8 h), 13% and 52% of those measured for polyurethane and cement–sodium-silicate systems, respectively, thereby minimising the thermal-runaway risk during bulk injection. Laboratory micro-CT confirmed 85% reduction in connected porosity (> 50 μm) and crack-free coal–grout interfaces. Field trials in the 102 auxiliary transport roadway (No. 3 coal seam, Hongqinghe Mine, Inner Mongolia, China) reduced O 2 concentration from 9 to 17% to 1–5% and decreased CO to 0 ppm within 30 d under mining-induced dynamic loading. The 28-d compressive strength reached 30.1 MPa (w/c = 0.7) while zero bleeding or shrinkage cracks were observed. Raw-material cost analysis shows GC (USD 185 t − 1 ) achieves 35% lower life-cycle cost than polyurethane over a 5-year horizon. With ΔTmax well below the 60 °C thermal-safety limit adopted in Chinese coal-mine grouting practice (AQ/T 1089–2020, a standard issued for polymeric materials and used here as a conservative benchmark) and goaf O 2 maintained below the 7% critical oxygen concentration specified in GB 51,078 − 2015, GC offers a low-exotherm, fire-resistant and environmentally benign alternative to organic sealants for coal-mine fire prevention.
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高影响因子
Nature Communications
·
2026
·
IF 18.1
Zhang Hao,Wu Jishan,Cao Xin,Guo Jingjing,Elimelech Menachem,Wang Yunkun
Nanofiltration (NF) membranes are essential for water purification. However, their performance is still largely optimized through empirical methods, as polyamide crystallinity remain difficult to control in scalable interfacial polymerization processes. In this study, we introduce an ultra-low-temperature interfacial polymerization strategy at −20 °C that enables direct polyamide chain assembly, suppresses crystallization, and forms a smooth, defect-free, fully amorphous selective layer. Comprehensive characterization confirms the formation of a homogeneous amorphous network, enabling a fourfold increase in water permeability and a threefold improvement in Cl - /SO 4 2- selectivity compared with room-temperature controls, surpassing high-performance NF membranes. The smooth surface further improves the antifouling performance of the NF membrane. Life cycle assessment based on experiments with real industrial wastewater, demonstrate that using the fabricated membrane can reduce treatment costs by 79.1%. This work establishes temperature-controlled chain assembly as a scalable lever for NF design and provides a practical pathway toward next-generation membranes for water treatment.
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APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
·
2026
·Vol. 132
·期 9
·949
·
IF 3
Chérif Ichraf,Ousji Rached,Dendeni Maha,Mejri Asma,Hamrouni Abdessalem,Linoubli Lazhar,de la Presa Patricia,Ferhi Mounir,Gao Yanan
This study reports a plant-mediated synthesis of zinc oxide nanoparticles (G-ZnO-NPs) using cinnamon bark extract during the zinc oxalate precipitation step. The extract acts as both an aqueous precipitation medium and a capping agent with cinnamaldehyde identified as the predominant phytochemical and coumarin as a comparatively minor constituent. These phytochemicals modulate particle growth and defect formation, thereby tailoring the physicochemical properties of the resulting nanoparticles. The properties of G-ZnO-NPs were systematically compared with those of commercial ZnO (C-ZnO) and ZnO nanoparticles synthesized via zinc oxalate precipitation in water (W-ZnO-NPs). Relative to both reference materials, G-ZnO-NPs exhibit reduced particle agglomeration, a remarkable particle size reduction (15.9 nm), an increased specific surface area, a lower band gap energy, and more efficient separation of photogenerated electron-hole pairs partly attributable to defect-mediated charge trapping, thereby resulting in a higher photocurrent density and a lower charge-transfer resistance. Collectively, these features contribute to enhanced photocatalytic and antibacterial performance. Under xenon-lamp irradiation, G-ZnO-NPs achieve 98.7% degradation of methyl orange (MO) within 150 min, compared with 83.6% and 88.9% for W-ZnO-NPs and C-ZnO, respectively, with corresponding first-order kinetic constants of 0.0289, 0.0118 and 0.0146 min -1 . Moreover, G-ZnO-NPs exhibit good structural stability and satisfactory recyclability after five consecutive photodegradation cycles, with hydroxyl radicals (OH . ) and photogenerated holes (h + ) identified as the predominant reactive species involved in MO degradation. In addition, G-ZnO-NPs demonstrate superior antibacterial activity than both reference ZnO samples particularly against Escherichia coli and Bacillus subtilis . These results highlight the potential of the cinnamon-based synthesis method as an eco-friendly strategy for producing ZnO-NPs with tailored properties offering a dual benefit for addressing water pollution and antibacterial resistance.
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高影响因子
Food Biophysics
·
2026
·Vol. 21
·期 3
·120
·
IF 3.9
Aabideen Muhammad Zain Ul,Geng Lijing,Shafique Aqsa,Fu Hang,Huang Wei,Wang Dan,Jia Dongsheng,Wang Ao,Qi Rong,Tertulliano Mbinga Isequias Elamba,Wei Zhou
Although catechins are strong dietary antioxidants with proven health benefits, yet they are very sensitive and unstable under normal condition to be used in practical food applications. To address this, a food-grade delivery system was developed through pH-driven co-assembly of catechin (CAT) with soy protein isolate (SPI), forming composite microspheres without the addition of chemical solvents or crosslinkers. The final assembly pH was identified as the primary factor affecting encapsulation, achieving a loading of 62.01%. The resulting microspheres (~ 16.8 nm) were stable, with analyses confirming encapsulation via hydrogen bonding and hydrophobic interactions, alongside a crystalline-to-amorphous transition of catechin. This improved stability under heat, salt, and pH stress while preventing loss in antioxidant activity. When applied to emulsified beef balls, 1.0% SPI-CAT reduced cooking loss (27% to 21%), increased yield (78%), and improved texture without affecting sensory quality. By linking molecular-scale composite characterization directly to functional performance in a real meat matrix within a single study, these results highlight its potential as a plant-based ingredient for stabilizing bioactives in food systems. Graphical
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高影响因子
JOURNAL OF POLYMER RESEARCH
·
2026
·Vol. 33
·期 9
·380
·
IF 3.5
Yu Xiaohong,Wu Ye,Lin Xinyue,Bektursun Gulina,Wu Zihan,Lyu Yongmei,Li Fengwei,Wang Dujun,Jin Wenbin
Uncontrolled bleeding and secondary bacterial infections are major challenges in emergency trauma care and surgery, making the development of dressings with rapid hemostatic and efficient antibacterial functions clinically significant. In this study, a multifunctional hydrogel was prepared by covalently grafting tannic acid (TA) onto chitosan (CS), cross-linking the composite with gelatin and oxidized dextran via dynamic Schiff base reaction, and introducing ε-poly-L-lysine. TA-CS interactions enhanced the structural stability and antioxidant capacity of the hydrogel. In vitro experiments confirmed its excellent hemostasis (minimum clotting index 35.54%), broad-spectrum antibacterial activity (> 98% against Escherichia coli and Staphylococcus aureus ), good biocompatibility, high swelling ratio (up to 2588%), and porous 3D structure (conducive to exudate absorption and tissue repair). Integrating multiple key functions, this hydrogel holds broad prospects in wound healing and infection control.
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高影响因子
CHINESE JOURNAL OF POLYMER SCIENCE
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2026
·
IF 4.6
Liu Guan-Jun,Yan Mei-Ling,Tian Zhen,Wang Lu,Yang Fan,Wang Rong-Guo
Hot pressing is widely used to tailor the structures and properties of polymer composites. However, how it drives structural evolution and thereby affects barrier, mechanical, and thermal properties remains insufficiently understood. In this work, graphene oxide-grafted carbon nanotube/polyamide 6 (GO- g -CNT/PA6) composites were subjected to hot pressing at different radial expansion ratios ( ε =0, 2, and 4) to investigate the flow-induced structural evolution and the resulting property changes. Scanning electron microscopy and transmission electron microscopy observations revealed that hot pressing promoted the rearrangement and preferential alignment of the hybrid nanofillers, while two-dimensional wide-angle X-ray diffraction confirmed the enhanced crystalline orientation after hot pressing. Differential scanning calorimetry showed increased crystallinity in both the neat PA6 and GO- g -CNT/PA6 composites. Representative positron annihilation lifetime spectroscopy analysis further indicated a reduction in the fractional free volume, whereas the characteristic size of individual free-volume holes remained nearly unchanged. The results indicate that the optimal hot-pressing condition is property-dependent. A moderate deformation at ε =2 is more favorable for improving the hydrogen barrier and tensile properties, whereas a stronger deformation at ε =4 is more effective in promoting in-plane heat transport. These findings establish a correlation between the processing, structural evolution, and multifunctional properties of GO- g -CNT/PA6 composites, providing guidance for the design of PA6-based liner materials for Type IV hydrogen storage vessels.
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高影响因子
Science China-Technological Sciences
·
2026
·Vol. 69
·期 11
·2120106
·
IF 5.1
Li Hongyang,Guo Zelin,Liu Zhan,Nie Changda,Liu Xinjian,Rao Zhonghao
Leveraging the advantages of high heat storage density and stable phase transition temperature, phase change materials (PCMs) have become one of the primary approaches to achieving continuous supply of renewable energy. Due to the risk of PCM leakage and poor cyclic stability, the utilization of PCMs in industry is severely limited. Generally, porous materials are used for PCM encapsulation to prevent leakage. However, due to the poor interface compatibility between porous materials and PCMs, the composite materials suffer from incomplete PCM injection and low enthalpy value. This study used polydopamine (PDA)-modified melamine foam (MF) to improve the encapsulation of polyethylene glycol (PEG) to reveal the effect of molecular modification on the thermal performance of the composite PCMs. The results indicate that with increasing PDA modification time, the adsorption capacity of MF for PEG gradually improves, the leakage of MF-based PCMs is alleviated, and the enthalpy value increases. Furthermore, by altering the molecular weight of PEG, the strengthening effect of PDA molecular modification on the heat storage capacity of MF-based PCMs is verified, and this effect is universal for polyethylene glycol materials. This study reveals that molecular modification is useful in improving the interface compatibility and heat storage capacity of the porous-based phase change composites. It fills the gap in the analysis of the influence pattern and mechanism of molecular modification on the change of phase transition enthalpy.
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ENVIRONMENTAL GEOCHEMISTRY AND HEALTH
·
2026
·Vol. 48
·期 14
·555
·
IF 4.3
Chen Rui,Yao Runfang,Chen Yuyun,Zhou Yifan
Antibiotic contamination in soil and soil salinization are both hot issues in environmental research. Amendments can modify the physicochemical properties of saline–alkali soil, thus affecting the occurrence forms and bioavailability of antibiotics. This study investigated the effects of pig manure and biochar on oxytetracycline (OTC) and sulfamethoxazole (SMX) in saline–alkali soil. The results showed that appropriate amendment dosages effectively reduced antibiotic bioavailability. At 7 days post-application, OTC bioavailability was minimized with 2% biochar, achieving a 50.34% reduction. However, higher biochar dosages increased OTC bioavailability. In contrast, SMX bioavailability consistently decreased with increasing dosages of both amendments. Soil salinization was found to increase antibiotic bioavailability, but under increasing soil salinity (from a non-saline control to 7 g/kg), the addition of 2% biochar inhibited OTC bioavailability by 39.40% and constrained the increase in SMX bioavailability to a mere 3.83%. In comparison, 2% pig manure initially increased and then decreased OTC bioavailability, while directly reduced SMX bioavailability by 32.06%. The amendments promoted the transformation of soil organic pollutants into more bound or residual forms, with biochar being more effective for OTC and pig manure for SMX. After 60 days of applying the two amendments, the bioavailability of OTC and SMX in the soil were significantly reduced. Specifically, 2% biochar decreased their bioavailability by 83.03% and 65.21% respectively, whereas 2% pig manure led to reductions of 50.47% and 60.42%, respectively. These findings provide a theoretical basis for the remediation of antibiotic-contaminated saline–alkali soils and the mitigation of associated ecological risks.
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高影响因子
Nature Communications
·
2026
·
IF 18.1
Huang Kai,Liu Hui-Zhi,Liu Yuan,Lyu Jia-Yan,Zhang Qing-Yi,Feng Zi-Yuan,Wang Zi-Lin,Dong Hui,Nie Rong,Zhang Yi-Wen,Zhang Yue-Qi,Zeng Yi,Xie Hui-Qi,Zhou Zhou,Shen Bin
Osteoarthritis (OA) remains difficult to treat because drug transport within cartilage is restricted by its dense extracellular matrix and rapid joint clearance. Here we show that hybrid exosomal nanomotors (CAP-Mn/140@hyExos) convert pathological reactive oxygen species (ROS) into transport-driving cues to overcome diffusion-limited transport within cartilage. In the oxidative OA microenvironment, manganese dioxide (MnO₂) catalyzes H₂O₂ decomposition, driving ROS-responsive transport, while a cartilage-targeting peptide enhances matrix interaction, together promoting cartilage accumulation. This strategy achieves deeper penetration (~140 μm), greater cellular uptake (~2.5-fold), and prolonged intra-articular retention (~30% remaining at two weeks). Enhanced transport enables efficient intracellular delivery of miR-140 and MnO₂ nanoparticles, attenuating oxidative stress and promoting cartilage regeneration. In a rat OA model, this therapeutic strategy improves gait performance, restores subchondral bone microarchitecture, and suppresses OA progression. These findings establish pathological microenvironments as endogenous drivers of intratissue drug transport, providing a transport-regulated strategy for drug delivery in transport-restricted tissues.
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EMBO Molecular Medicine
·
2026
·
IF 7.9
Liu Lijie,Yan Mengrong,Liang Ruoxu,Wu Qingxin,Qu Changbin,Wu Huiqi,Liao Zhi,Chen Huiyu,Zou Jingjing,Sun Zeyun,Niu Dongyu,Wu Liyuan,Zhao Li,Dai Jialing,Shen Jialun,Zhang Long,Zhang Wei,Peng Wei
Respiratory syncytial virus (RSV) remains a major cause of severe respiratory disease, and stabilization of the prefusion (preF) conformation of the F glycoprotein is central for vaccine development. Here, we report a structure-guided engineering strategy that enhances preF stability by reducing the hydrophobic cavity within the trimeric F protein. Targeted modifications at metastability-associated sites generated RVF-88, a disulfide-free stabilized preF immunogen that preserves key neutralizing epitopes, including antigenic site Ø, while exhibiting improved structural integrity and long-term storage stability. Formulated as an unadjuvanted bivalent vaccine, RVF-88 elicited potent neutralizing antibody responses and durable immune protection lasting up to 5 months in mice. Vaccination also protected both mice and cotton rats against RSV challenge. Structural analyses confirmed the intended cavity-reduction design, revealing a reduced apical hydrophobic cavity volume and surface area while maintaining the prefusion architecture. Together, these findings establish hydrophobic cavity reduction as a rational strategy for stabilizing prefusion RSV F and provide a promising next-generation vaccine candidate with improved stability and immunogenicity for further clinical development.
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高影响因子
Nature Communications
·
2026
·Vol. 17
·期 1
·9106
·
IF 18.1
Sui Shanying,Wang Jingxing,Lu Yufang,Yang Yufan,Song Zhenhua,Yin Chao,Zhang Yixian,Zhang Yi,Quan Huafeng,Guo Shaoqiang,Sun Zhifang
Removing organic pollutants from water is essential for preserving global ecosystems. However, challenges related to recyclability and material stability hinder effective treatment. Inspired by the mortise-and-tenon structure, a series of Ca 2+ -enhanced amino acid-intercalated layered double hydroxide aerogels featuring an interlocked framework was developed via the structural memory effect and supercritical drying. The aerogels achieve a balance of compressive strength (40.1 − 45.5 MPa) and toughness, overcoming the brittleness of conventional inorganic aerogels. They can remove a broad range of water pollutants, including tetracycline, doxycycline hydrochloride, methyl orange, Congo red and malachite green, with efficiencies of 95.4 − 99.9%, while retaining 87% of their initial efficiency after five regeneration cycles and enabling pollutant detection with a detection limit of 710 nM. The aerogels also exhibit robust stability under liquid nitrogen and butane flame exposure, along with flame resistance (limiting oxygen index ≈ 100%). These findings highlight their potential for water purification under harsh environmental conditions.
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高影响因子
危险品化学品经营许可证（带存储）