CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Xingyu Liu,Jinwei Gao,Qianming Wang
The low resistance to moisture will be the main obstacle for the perovskites used in device package and solar cell application. Most of literatures refer to the route that the quantum dots should be incorporated into a wide variety of stabilized hosts. However, the generation of protecting layers requires complicated treatments and decreases solubility or dispersity. Moreover, morphological control of perovskite nanocrystals with the assistance of covering substrate is a big challenge. Self-assembly of colloidal nanocrystals into ordered architectures has caused considerable interests and enabled new ways to manipulate the physicochemical properties for targeted applications. Herein, we describe how inorganic halide perovskites (CsPbBr 3 ) with five different shapes (cubic, dot, sheet, ring and complex-coated) are formed by adjusting the sequence of PbBr 2 , 2-mercapto-3-methyl-4-thiazoleacetic acid (MMTA) and water. Realization of long-term stability and high efficiency requires innovative designs in both internal chemical structure and external interface engineering. PbBr 2 improves the ionic nature of CsPbBr 3 due to its cation supplement strategy. MMTA plays an important role in cross-linking process and the hydrogen bond/coordination interactions can passivate the interfacial surface for optimizing the microstructure. Water is not always detrimental in producing irreversible degradation. The shape evolution from the individual particles into much extended structure leads to the formation of complex-coated- CsPbBr 3 (CC- CsPbBr 3 ). It can retain 40% of its original emission intensity in water for 36 h, whereas the typical cubic CsPbBr 3 exhibits poor performance during water tolerance experiments and has been completely quenched within 12 h. A wide color gamut system with 153% of National Television System Committee (NTSC) space is developed for CC- CsPbBr 3 .
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
·
2021
·
IF 6.165
Hongjun Zang,Jing Lou,Shuolei Jiao,Huanxin Li,Yannan Du,Jiao Wang
Chitin and its derivatives contain biologically fixed nitrogen elements, which can provide nitrogen sources for N-containing chemicals. Herein, a series of pyridinium-based ionic liquids were synthesized to directly catalyze the conversion of N -acetyl-D-glucosamine (NAG, the monomer of chitin) to 3-acetamido-5-acetylfuran (3A5AF). The yield of 3A5AF in 1-carboxymethyl pyridinium chloride ionic liquid reached 37.49%, without any additives. Using B 2 O 3 and CaCl 2 as additives, the optimum yield increased to 67.37% at 180 °C in 20 min. In addition, HPLC-MS analysis has been utilized to elucidate the reaction mechanism. This research on turning “waste” into “wealth” opens up new ways for the utilization of biomass waste, which not only reduces environmental pollution but also has potential economic value.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2020
·
IF 4.65
Ziqing Li,Pengfei Zhu,Jimin Ding,Yang Chen,Zhenyan Wang,Nianjing Ji,Xiulan Duan,Huaidong Jiang
Inorganic upconversion materials show significant importance in both basic research and applied area, and searching for suitable host material and understanding of fundamental photophysical process are particularly worth studying in upconversion application. Herein, a heavily Yb 3+ -substituted langbeinite-type Rb 2 Ti 0.80 Yb 1.20 (PO 4 ) 3 (RTYP) millimeter-sized single crystal, which has been successfully grown by high temperature solution method, exhibits efficient dual-color upconversion photoluminescence under 980 nm excitation. The lifetimes of two-photon blue emission and one-photon red emission are 4.1 μs and 17.1 μs, respectively. X-ray structural analyses reveal that the dual-color emissions are ascribed to disordered Yb 3+ -Ti 4+ pairs and crystal defect, and the higher intensity of red emission is attributed to Yb 3+ -defect energy transfer activated by Ti 4+ . Notably, the blue emission originates from cooperative luminescence of Yb 3+ dimer, and the red emission originates dominantly from the cooperative sensitization of the intrinsic defect caused by excited Yb 3+ dimer. Moreover, RTYP with disordered structure shows high thermal stability up to 1,150 °C. This work not only demonstrates the promising potential of langbeinite-type materials in multicolor upconversion application, but also sheds light on the photophysical process associated with disordered crystal structure.
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2020
·
IF 4.939
Hongmei Zhao,Tingting Zhang,Dongyu Shan,Ying Zhu,Ge Gao,Ye Liu,Jing Liu,Meiying Liu,Wansheng You
An intervening barrier for photocatalytic water decomposition and pollutant degradation is the frustratingly quick recombination of e − - h + pairs. Delicate design of heterojunction photocatalysts by coupling the semiconductors at nanoscale with well-matched geometrical and electronic alignments is an effective strategy to ameliorate the charge separation. Here a facile and environment-friendly l -cysteine-assisted hydrothermal process under weakly alkaline conditions is demonstrated for the first time to fabricate ZnIn 2 S 4 /In(OH) 3 hollow microspheres with intimate contact, which are verified by XRD, SEM, (HR)TEM, XPS , N 2 adsorption-desorption, UV–Vis DRS and photoluminescence spectra. ZnIn 2 S 4 /In(OH) 3 heterostructure (L-cys/Zn 2+ = 4, molar ratio) with a band-gap of 2.50 eV, demonstrates the best photocatalytic performance for water reduction and MB degradation under visible light, outperforming its counterparts (In(OH) 3 and ZnIn 2 S 4 ). The excellent activity of ZnIn 2 S 4 /In(OH) 3 heterostructure arises from the intercrossed band-edge positions as well as the unique hollow structure with large surface area and wide pore-size distribution, which are beneficial for the efficient charge migration from bulk to surface as well as at the interface between ZnIn 2 S 4 and In(OH) 3 . This work provides an efficient and eco-friendly strategy for one-pot synthesis of heterostructured composites with intimate contact for photocatalytic application.
✓ 已验证
产品关联
DOI
高影响因子
LIFE SCIENCES
·
2020
·
IF 3.647
Zhuo Wang,Weixiao Nan,Huazhe Si,Shiyong Wang,Haihua Zhang,Guangyu Li
Aims Pantothenic acid (PA) has been applied to treat alopecia, but the underlying mechanism is still unclear. Our study aims to explore the underlying mechanism of PA in regulating hair follicle (HF) growth. Main methods Mink HFs and dermal papilla (DP) cells were isolated and cultured in vitro . HFs and DP cells were treated with 0, 10, 20, 40 μg/ml PA. The effect of PA on HF growth, DP cell proliferation, cell cycle distribution, cell migration, and insulin-like growth factor-1 (IGF-1) and vascular endothelial growth factor (VEGF) expressions in DP cells was measured. Moreover, the effect of PA on inhibitor of DNA binding 3 (ID3)/Notch signaling pathway was analyzed. Subsequently, ID3 was silenced to validate whether ID3/Notch signaling pathway was involved in regulating DP cell proliferation by PA. Key findings Both 20 μg/ml and 40 μg/ml PA promoted HF growth, G1/S transition of DP cells and IGF-1 and VEGF expressions in DP cells, while only 20 μg/ml PA promoted cell viability and the migration of DP cells. Thus 20 μg/ml PA was chosen for the following experiments. PA treatment was found to up-regulate ID3 expression but down-regulate Notch receptor 1 (Notch1) and Notch signaling targets expressions. Furthermore, ID3 knockdown reversed PA-induced cell proliferation and inhibition of Notch1 and Notch signaling targets expressions, indicating that PA-induced DP cell proliferation and inhibition of Notch signaling were mediated via up-regulation of ID3. Significance This study provides an underlying mechanism related to the effect of PA on stimulating DP cell proliferation.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2020
·
IF 2.369
Xiaolin Zhao,Ji Mi,Yitong Dai,Guijin He,Yongsheng Guo,Wenjun Fang
exo-Tetrahydrodicyclopentadiene can serve as both the propellant and coolant in hypersonic vehicles. However, its applications are restricted by the poor properties of ignition and combustion to some extent. Fuel additives such as appropriate alcohols have the ability to overcome these deficits. Research on thermophysical properties of the mixtures composed of exo-tetrahydrodicyclopentadiene and fuel additives can provide important information for the research of fuel additives. In this work, densities and viscosities of the ternary system of exo-tetrahydrodicyclopentadiene (1) + n-decane (2) + iso-butanol (3) and three corresponding binary systems have been measured over the whole composition range in the temperature range from 293.15 to 333.15 K with an interval of 5 K and at pressure p = 0.1 MPa. The values of excess molar volumes (VmE) and viscosity deviations (Δη) of three binary systems and the ternary system were calculated and then fitted to the Redlich–Kister equation and four semi-empirical equations, respectively. The variations of VmE and Δη were explained from the viewpoints of intermolecular forces and structural effects. Furthermore, the Jouyban–Acree model was used to correlate the values of densities (ρ) and viscosities (η) of the studied mixtures with high accuracy.
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2020
·
IF 10.652
Junyu Fan,Meimei Zuo,Zhaoxia Ding,Zhiwei Zhao,Jie Liu,Bo Sun
A promising and practicable catalyst is the key challenge for industrial perspective to promote photocatalytic nitrogen fixation. In this study, a new 0D /2D heterojunction, oxygen vacancy-induced In(OH) 3 /carbon nitride (OV-In(OH) 3 /CN), was synthesized by generating In(OH) 3 nanoparticles on g-C 3 N 4 nanosheets in the presence of glyoxal through a facile and readily precipitation growth method at 60℃and under atmospheric pressure. The existence of oxygen vacancies, structure, morphology and optical-electronic properties of the composite were characterized by HRTEM, XPS and EPR analysis and other measurements. The OV-In(OH) 3 /CN heterojunction exhibited excellent photocatalytic activity for nitrogen fixation with a good chemical stability. The OV-In/CN-3 sample reached the maximum NH 3 generation rate to be 3.81 mM*h −1 *g −1 , which was about 10 times as that of pure g-C 3 N 4 and was also higher than that of other catalysts reported. Though the In(OH) 3 in heterojunction was demonstrated incapable of producing photogenerated electrons under vis-light irradiation, its oxygen vacancy was found to “receive” and “trap” some excited electrons from g-C 3 N 4 , promoting electron-hole pairs separation efficiency and prolonging the lifetime of carriers. And it also can introduce many chemisorption sites for N 2 . Those are the two key reasons for its high photocatalytic activity.
✓ 已验证
产品关联
DOI
高影响因子
BIOMEDICAL CHROMATOGRAPHY
·
2019
·Vol. 34
·期 3
·e4767
·
IF 1.748
Yong-hong Liu,Ting-ting Du,Jing-yuan Wan,Hua Zhao,Dan Huang,Jian-sha Li,Xin-hui Jiang
Disorders of certain branched-chain amino acids may be associated with the occurrence and development of non-alcoholic fatty liver disease. Measurement of related branched-chain amino acid levels could provide a reference for the clinical and scientific research of the non-alcoholic fatty liver disease. An established HPLC–FLD method was used to quantify aspartic acid, glutamate, glutamine, glycine, taurine, tyrosine, 4-amino butanoic acid, tryptophan, methionine, valine, phenylalanine, isoleucine and leucine in mouse brain tissue. Brain tissue samples mixed with internal standard (3-aminobutyric acid) were processed, then derivatized with 2- O -phthaldialdehyde, and finally separated on an ODS2 column through gradient elution at a flow rate of 1.0 ml·min −1 . The excitation and emission wavelengths were set at 340 and 455 nm, respectively. The mobile phase A was 100% methanol and the mobile phase B consisted of 30 mmol·L −1 sodium acetate (pH 6.8). The injection volume was 20 μl and the single run time was 45 min. Several parameters, accuracy, precision, and stability, were verified and the results showed the established method had good sensitivity and resolution for all of the 13 compounds and internal standard in mouse brain.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of the Taiwan Institute of Chemical Engineers
·
2019
·
IF 3.834
Zhen Chen,Guangli Li,Yuejun Liu,Pu Shi,Fuzhi Li
Highly efficient and low-cost catalysts are greatly desirable for oxygen reduction reaction (ORR) in the cathode of metal-air batteries. Herein, a novel Co 1-x S/C-3/N-KB catalyst is prepared by a facile process with cheap raw materials. The electrocatalytic performance of Co 1-x S/C-3/N-KB for ORR are investigated systematically. As results, Co 1-x S/C-3/N-KB exhibits a half-wave potential of 0.72 V and a limiting current density of 6.0 mA·cm −2 , comparable to the commercial Pt/C. Moreover, by means of Koutecky–Levich and RRDE techniques, the catalyst is confirmed to catalyze ORR at a four-electron pathway. Besides, chronoamperometric studies indicate a better catalytic stability of Co 1-x S/C-3/N-KB than that of Pt/C with the current density retention rates of 93.4% and 88.3%, respectively. In addition, during the accelerated durability test, Co 1-x S/C-3/N-KB shows only 11.5 mV negative shift of half-wave potential after 5000 cycles, even better than Pt/C (34.6 mV negative shift). When used as cathode catalyst for primary Al-air battery, the Co 1-x S/C-3/N-KB catalyst exhibited excellent discharge voltage and better stability than Pt/C. The excellent ORR catalytic activity and stability of Co 1-x S/C-3/N-KB can be due to the synergistic effect between the Co 1-x S/C active sites and the N-KB support, which is not only beneficial to oxygen adsorption but also promotes efficient electron transfer, thus facilitating the oxygen reduction process. Besides, the coated/doped carbon and doped nitrogen in Co 1-x S/C particles also have certain contribution, enhancing the electronic conductivity and catalytic stability, therefore facilitating the electronic transfer inside Co 1-x S/C active particles during the oxygen reduction process.
✓ 已验证
产品关联
DOI
高影响因子
Translational Oncology
·
2022
·
IF 4.803
Yongxiu Du,Yanlan Yang,Wenbo Zhang,Chenxi Yang,Pu Xu
Oral squamous cell carcinoma (OSCC) is a usual oral cancer. Therefore, it's essential to identify targets for its early diagnosis and therapy. This research aimed to explore the roles of human β-defensin-3 (hBD-3) and nuclear factor-kappa B (NF-κB) p65 in the pathogenesis and progression of OSCC. The connection between NF-κB p65 and the carcinogenesis of oral cancer was analyzed by immunohistochemical staining. The relative expressions of hBD-3 and NF-κB p65 in OSCC cells were evaluated by qRT-PCR and Western blot. Afterward, hBD-3 was knocked down, and NF-κB p65 was overexpressed. The cell viability and invasion were tested via CCK-8 and Transwell experiment, and the expression of hBD-3, NF-κB p65, and its downstream molecules was evaluated by Western blot. The expression of NF-κB p65 was increased with the aggravation of the oral submucosal fibrosis. HBD-3 and NF-κB p65 were high-expressed in OSCC cells. The viability and invasion abilities of OSCC cells that knocked down hBD-3 were markedly decreased, while they were restored by the overexpression of NF-κB p65. The expressions of NF-κB p65 and c-myc were diminished while IκB and p21 were raised with the knockdown of hBD-3. After overexpression of NF-κB p65, the expression of hBD-3 and IκB did not change markedly, while c-myc was increased and p21 was decreased dramatically. HBD-3 and NF-κB p65 facilitate the proliferation and invasion of OSCC cells, and hBD-3 may promote this process by governing the expression of NF-κB p65 and its downstream c-myc and p21.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
REACTIVE & FUNCTIONAL POLYMERS
·
2022
·
IF 4.966
Zhi-Ming Wu,Yu Cao,Jin-Han Guo,Xiu-Qin Fang,Cheng-Mei Liu
A novel bio-based benzoxazine monomer (VBOZ-7, 7-vinyl-3-phenyl-3,4-dihydro- 2H -1,3-benzoxazine) bearing polymeriable vinyl and 1,3-benzoxazine functionalities was synthesized from 3-hydroxycinnamic acid through successive decarboxylation reaction and Mannich condensation .The styrene-like bifunctional monomer underwent radical polymerization to obtain soluble P(VBOZ-7) which still remainining polymeriable benzoxazien pendent groups. The reactive P(VBOZ-7) possessed excellent solubility just like polystyrene , and also showed excellent thermal stability under 220 °C verified by differential scanning calorimeter (DSC) results. When the linear P(VBOZ-7) was heated over 240 °C, the remaining benzoxazines polymerized rapidly to form crosslinked structure. Thermogravimetric analysis (TGA) results showed that both linear and crosslinked P(VBOZ-7) possessed high char-formability at 800 °C. Cone calorimeter test (Cone test) proved that in situ crosslinking reaction strikingly improved the flame-retardancy of P(VBOZ-7). The total heat release of the crosslinked P(VBOZ-7) was only 6.7 MJ/m 2 , far below the value of polystyrene (109.4 MJ/m 2 ). Undoubtedly, the P(VBOZ-7) consisting of C, H, O, N atoms is an intrinsically green flame-retardant polymer with excellent solution processibility.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MEDICINAL CHEMISTRY
·
2019
·
IF 6.054
Yao-Ling Wang,Sha Liu,Zhu-Jun Yu,Yuan Lei,Meng-Yi Huang,Yu-Hang Yan,Qiang Ma,Yang Zheng,Hui Deng,Ying Sun,Chengyong Wu,Yamei Yu,Qiang Chen,Zhenling Wang,Yong Wu,Guo-Bo Li
The emergence and spread of bacterial pathogens acquired metallo-β-lactamase (MBL) and serine-β-lactamase (SBL) medicated β-lactam resistance gives rise to an urgent need for the development of new dual-action MBL/SBL inhibitors. Application of a pharmacophore fusion strategy led to the identification of (2′S)-(1-(3′-mercapto-2′-methylpropanamido)methyl)boronic acid (MS01) as a new dual-action inhibitor, which manifests broad-spectrum inhibition to representative MBL/SBL enzymes, including the widespread VIM-2 and KPC-2. Guided by the VIM-2:MS01 and KPC-2:MS01 complex structures, further structural optimization yielded new, more potent dual-action inhibitors. Selectivity studies indicated that the inhibitors had no apparent inhibition to human angiotensin-converting enzyme-2 and showed selectivity across serine hydrolyases in E. coli and human HEK293T cells labeled by the activity-based probe TAMRA-FP. Moreover, the inhibitors displayed potentiation of meropenem efficacy against MBL- or SBL-positive clinical isolates without apparent cytotoxicity. This work will aid efforts to develop new types of clinically useful dual-action inhibitors targeting MBL/SBL enzymes.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）