INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2024
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IF 3.8
Jingwen Qian,Susu Liu,Zhongyu Wang,Mingyi Yu,Zheng Lian,Shule Zhang,Qin Zhong
In the typical wet flue gas denitration technology using sulfite solutions, the rapid free radical chain reaction of SO3•– oxidation by O2 is the main reason for the significant consumption of absorbents and inefficient denitration. The study utilizes l-ascorbic acid (VC) to inhibit the free radical chain reaction. VC combined with SO3•– to form stable compounds, which hindered the oxidation of SO3•– to SO5•– by O2, leading to an 80.7 mol % decrease in Na2SO3 consumption by adding millimolar-level VC. Compared to the sulfite solution, the best denitration efficiency of the VC/Na2SO3 mixture solution increased from 94.4 to 99.2 vol %, and the absorption time for absorption efficiency above 90 vol % was extended from 7 to 72 min. Additionally, a macro absorption model describing the rates of macro absorption was established based on various operating conditions.
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PROGRESS IN ORGANIC COATINGS
·
2024
·
IF 6.5
Mengchen Xue,Xiang Rao,Weihu Li,Jinghua Du,Wenhe Guo,Wangqin Zhou,Xiaoyu Dong,Le Wu,Guobing Zhang,Yunsheng Ding
A wide application of bio-based waterborne polyurethanes (BWPU) in the synthetic leather is the main direction in the future, however, it has been a great challenge for its development because of the poor mechanical properties and water resistance of BWPU. To address this issue, bio-based poly(trimethylene carbonate) diols (PTMC-OH) with a theoretical molecular weight of 2000 g/mol was prepared via ring-opening polymerization of trimethylene carbonate and 1,4-butanediol as an initiator. PTMC-OH, bio-based l -lysine diisocyanate as building blocks, and trimethylolpropane as a crosslinking agent were employed to prepare a series of linear and crosslinked bio-based waterborne polyurethanes (LBWPU and CBWPU). Remarkably, CBWPU-1 % film with crosslinked structure had high tensile strength and toughness shown as 41.5 MPa and 131 MJ·m −3 , respectively, while it also showed excellent hydrolysis resistance with the ignorable degradation in aqueous solution after 35 days since the weight loss of about 1.4 wt%. In addition, the synthetic leather coating made from CBWPU-1 % exhibited exceptional wear resistance, enduring 50,000 rubs without damages on the CBWPU coating. This work presents a facile and efficient method for the synthesis of BWPU and applying them to manufacture the bio-based synthetic leather.
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JOURNAL OF HAZARDOUS MATERIALS
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2025
·
IF 11.3
Tao Cang,Lu Lv,Yue Yin,Dou Wang,Kan Shao,Zhenlan Xu,Xinquan Wang,Yanhua Wang
Perfluorooctanoic acid (PFOA) and perfluorohexane sulfonate (PFHxS), as persistent global contaminants, pose substantial threats to pollinators like honeybees ( Apis mellifera L.), yet their sub-lethal effects remain insufficiently explored. Here, we exposed bees to environmentally relevant concentrations (0.5–50 μg/L) of PFOA and PFHxS for 10 days, assessing midgut toxicity through pathology, metabolomics, and gene expression, and examined curcumin (Cur) as a potential mitigator. Although acute toxicity assays indicated relatively high LC₅₀ values (266–331 mg/L), sub-lethal exposures induced pronounced midgut injury, characterized by decreased epithelial cell density and thinning of the protective gel layer. Disruption of glycerophospholipid metabolism was detected, impairing membrane integrity. Additionally, PFOA and PFHxS downregulated barrier integrity genes ( ZO-2 and Mucin-1 ), while upregulating inflammatory ( Eiger and Relish ) and apoptotic indicators ( Caspase-3 , Caspase-8 , and Caspase-9 ). For several sub-lethal endpoints, PFHxS triggered more pronounced effects than PFOA. Notably, curcumin treatment restored midgut integrity and reversed many of the associated molecular disruptions. These results demonstrated that environmentally relevant concentrations of PFAS could substantially compromise honeybee gut health, offering critical insights for ecological risk assessments aimed at safeguarding these essential pollinators.
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JOURNAL OF CHROMATOGRAPHY A
·
2014
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IF 4.258
Wenhua Ji,Xiuli Ma,Hongkai Xie,Lingxiao Chen,Xiao Wang,Hengqiang Zhao,Luqi Huang
Dummy molecularly imprinted polymers (DMIPs) for simultaneously selective removal and enrichment of ginkgolic acids (GAs) during the processing of Ginkgo biloba leaves have been prepared. Two dummy template molecule with similar structural skeleton to GAs, 6-methoxysalicylic acid (MOSA, DT-1) and 6-hexadecyloxysalicylic acid (HOSA, DT-2), have been designed and synthesized. The performance of the DMIPs and NIPs were evaluated including selective recognition capacity, adsorption isotherm, and adsorption kinetics. The selective recognition capacity of the three GAs with four analogues on the sorbents illustrated that the DMIPs sorbents have high specificity for GAs. An efficient method based on DMIP-HOSA coupled with solid-phase extraction (SPE) was developed for simultaneously selective removal and enrichment of ginkgolic acids (GAs) during the processing of Ginkgo biloba leaves. The method showed excellent recoveries (82.5–88.7%) and precision (RSD 0.5–2.6%, n = 5) for licorice extracts, Gastrodia elata extracts and pepper extracts spiked at three concentration levels each (50, 100, 200 μg mL −1 ). The results indicated that GAs and standardized Ginkgo biloba leaves extracts could be obtained simultaneously through the DMIP-SPE.
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Toxics
·
2025
·Vol. 13
·期 6
·427
·
IF 4.1
Xinyi Xie,Jiayin Hou,Meng Li,Zhiyu Liu,Mengai He,Chenxi Li,Xiaohua Du,Liezhong Chen
Phoxim is a pesticide extensively applied in mulberry fields, and residues may persist on leaves even after the recommended pre-harvest interval. However, the potential risks of these residues toBombyx moriL. (Lepidoptera: Bombycidae) have long been overlooked. The results demonstrated that chronic low-dose exposure from the second to fifth instars significantly impaired silkworm development and silk production. Specifically, larvae in the 0.316 μg/mL treatment group (1/2 LC50) exhibited a significant reduction in body weight, while the cocoon shell ratio was significantly decreased in both the 0.079 μg/mL (1/8 LC50) and 1/2 LC50groups. Cocoon deformities were observed in the 0.032 μg/mL (1/20 LC50), 1/8 LC50, and 1/2 LC50groups. Histopathological analysis revealed silk gland damage in the treatment groups, with severity increasing with higher phoxim concentrations. Biochemical analyses indicated elevated malondialdehyde (MDA) levels accompanied by increased superoxide dismutase (SOD) and peroxidase (POD) activities. Notably, phoxim exposure selectively reduced juvenile hormone (JH) titers without affecting ecdysone titers. JH-regulated genes including the receptorsMet1andMet2, and transcription factorsKr-h1andDimmwere downregulated, accompanied by suppressed expression of the fibroin synthesis geneFib-H. These results collectively indicate that chronic low-concentration phoxim exposure disrupts endocrine regulation, damages silk gland integrity, and ultimately reduces silk production in silkworm.
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Acta Biomaterialia
·
2016
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IF 6.008
Qianming Lin,Yumeng Yang,Qian Hu,Zhong Guo,Tao Liu,Jiake Xu,Jianping Wu,Thomas Brett Kirk,Dong Ma,Wei Xue
Hydrogels have attracted much attention in cancer therapy and tissue engineering due to their sustained gene delivery ability. To obtain an injectable and high-efficiency gene delivery hydrogel, methoxypolyethylene glycol (MPEG) was used to conjugate with the arginine-functionalized poly( l -lysine) dendron (PLLD-Arg) by click reaction, and then the synthesized MPEG-PLLD-Arg interacted with α-cyclodextrin (α-CD) to form the supramolecular hydrogel by the host-guest interaction. The gelation dynamics, hydrogel strength and shear viscosity could be modulated by α-CD content in the hydrogel. MPEG-PLLD-Arg was confirmed to bind and deliver gene effectively, and its gene transfection efficiency was significantly higher than PEI-25k under its optimized condition. After gelation, MMP-9 shRNA plasmid (pMMP-9) could be encapsulated into the hydrogel matrix in situ and be released from the hydrogels sustainedly, as the release rate was dependent on α-CD content. The released MPEG-PLLD-Arg/pMMP-9 complex still showed better transfection efficiency than PEI-25k and induced sustained tumor cell apoptosis. Also, in vivo assays indicated that this pMMP-9-loaded supramolecular hydrogel could result in the sustained tumor growth inhibition meanwhile showed good biocompatibility. As an injectable, sustained and high-efficiency gene delivery system , this supramolecular hydrogel is a promising candidate for long-term gene therapy. Statement of Significance To realize the sustained gene delivery for gene therapy, a supramolecular hydrogel with high-efficiency gene delivery ability was prepared through the host-guest interaction between α-cyclodextrin and PEGylated arginine-functionalized poly( l -lysine) dendron. The obtained hydrogel was injectable and biocompatible with adjustable physicochemical property. More importantly, the hydrogel showed the high-efficiency and sustained gene transfection to our used cells, better than PEI-25k. The supramolecular hydrogel resulted in the sustained tumor growth inhibition meanwhile keep good biocompatibility. As an injectable, sustained and high-efficiency gene delivery system, this supramolecular hydrogel is a promising candidate in long-term gene therapy and tissue engineering.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
·
IF 7.7
Kok Bing Tan,Meixia Zheng,Junyan Lin,Yujing Zhu,Guowu Zhan,Jianfu Chen
Pullulan-based composite film can be a potential alternative packing material to non-environmentally friendly plastic wrap (PE) to preserve fresh-cut carrots. However, many developed pullulan-based composites either have high water vapor permeability (WVP) and high mechanical strength or vice versa, which limits the practicality of the developed packaging materials for potential commercialization. Herein, Abelmoschus manihot gum (AMG)/pullulan/magnesium L-ascorbate (MLA) was created as a green composite film (APL) to preserve fresh-cut carrots. The optimal amount of MLA was found to be 10 % (APL10), demonstrating a balance of lower WVP and greater mechanical strength and antioxidant performance than many pullulan-based films. This effectively solved many problems faced by other pullulan-based packaging films. After the fresh-cut carrots were packed with the composite film for 4 days, it was found that APL10 was effective in preserving the quality of carrots, in terms of freshness, weight loss rate, Vitamin C (VC), and malondialdehyde (MDA) content after 4 days of storage, much better than non-biodegradable PE. Thus, based on these findings, it is concluded that APL films have huge potential as a green packaging material for food to replace PE in the future.
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PLANT PHYSIOLOGY AND BIOCHEMISTRY
·
2025
·
IF 5.7
Qiaoran Ma,Guobing Tian,Shengchao Yang,Junwen Chen,Wei Fan,Ping Zhao,Yan Wang,Jiamin Liu,Yonglin Liu,Shuhui Zi,Shuran He
Planting vegetation under forests in agroforestry systems fosters sustainable agricultural development. However, Limited availability of biostimulants for agroforestry and unclear mechanisms of plant growth promotion. This study synthesized and evaluated a novel biostimulant, nanosilicon-based vermicompost leachate (NSVCL), using Panax quinquefolius L. as the research plant species for forest cultivation. Trichoderma harzianum (TH) was chosen to represent a biostimulant with broad-spectrum properties, and its application effects were compared with NSVCL. The regulatory effects of both on the physiological characteristics and rhizosphere soil microenvironment of P. quinquefolius were investigated, with untreated plants serving as controls. Compared to the control, NSVCL and TH increased the dry weight of P. quinquefolius roots 129.33 % and 23.50 %, respectively. NSVCL was applied more effectively than TH. Additionally, NSVCL markedly improved leaf anatomical traits, including palisade and spongy tissue thickness, overall leaf thickness, chloroplast number, and cuticle thickness. Application of NSVCL and TH significantly elevated the net photosynthetic rate (Pn) by 86.55 % and 60.92 %, respectively, and increased total chlorophyll content (TChl) by 24.91 % and 11.76 %. Biostimulants facilitated nutrient uptake and boosted antioxidant enzyme activity in P. quinquefolius . Partial least squares path modeling (PLS-PM) further demonstrated that both NSVCL and TH promoted plant growth by enhancing soil enzyme activity in forest environments. These findings underscore NSVCL's efficacy in improving P. quinquefolius growth under forest conditions and provide a practical foundation for advancing organic forest cultivation and sustainable forest-medicine integration.
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PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
·
2019
·
IF 2.87
Chenyu Su,Xiaoming Xia
The diamondback moth (DBM), Plutella xylostella (L.), is a major pest affecting cruciferous vegetables, and seriously affects the quality and yield of these vegetables. Diafenthiuron is a traditional thiourea-based insecticide , but it is rarely used to control pests on cruciferous vegetables due to its phytotoxicity on these vegetables under high temperature and light conditions. Thus, there is an ongoing need for more effective pesticides that can be used on cruciferous vegetables, possibly including new formulations of diafenthiuron. A new thiourea insecticide, methylthio-diafenthiuron, is intended to optimize the structure of diafenthiuron not only to preserve its insecticidal bioactivity but also to overcome its phytotoxicity to cruciferous vegetables, aiming to control insect pests on cruciferous vegetables. In this study, we compared the toxicity of methylthio-diafenthiuron to some frequently used insecticides on the third-instar larvae of DBM. The parental pupal duration was significantly longer under the treatment than in the control, but the pupal weight, fecundity, and hatching rate significantly decreased. By studying the changes in three detoxifying enzymes within 72 h after treatment with a sublethal concentration, the activity of CarE and ODM in the treatment group significantly increased at first and then decreased. In addition, methylthio-diafenthiuron clearly inhibited three kinds of ATPases in the DBM and significantly reduced the eclosion rate of the pupae . This research provides valuable information for the assessment and rational application of methylthio-diafenthiuron for the control of pests on cruciferous vegetables.
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
·
2021
·
IF 3.575
Ligang Xing,Yanmei Zhao,Mingzhu Gong,Xia Liu,Yuhui Zhang,Dan Li,Zefeng He,Ping Yan,Jidong Yang
In this study, Graphene Oxide (GO) was used to screen the binding with the aptamers of L-carnitine chiral enantiomers . The ssDNA library was prepared by the method of Lambda exonuclease . In addition, a simple casing device was designed to improve the purification and recovery efficiency of the small ssDNA fragments in the process of screening. Finally, more than 160,000 aptamer sequences were obtained by high-throughput sequencing. We determined the strongest affinity aptamer sequence, CA04, by the Resonance Rayleigh scattering (RRS) technology. We also analyzed the key binding sites (in the 16th position case) of the truncated aptamer sequence CAD10. Interestingly, we found that aptamer CA10 and CA06 were both C-rich bases through sequence alignment and analysis, and the aptamer CA10 was confirmed that the CA10 and CA06 were formed under acidic conditions (pH 4.5) by CD spectrum and ESI-MS analysis. The interaction between gold nanoparticles (AuNPs) and functionalized aptamer CA10 was analyzed. We used Site-directed mutagenesis design and QGRS Mapper to optimize aptamer CA10, where an optimal aptamer CA10-03 were obtained after affinity analysis. It is also proved to be an effective method to obtain stronger affinity aptamer. Meanwhile, Native-PAGE and UV spectrum analysis were performed on the mutation sequences, and the interaction with ThT was analyzed. Finally, it is hoped that my study can provide help for later identification and detection of L-carnitine .
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Analytical Methods
·
2015
·Vol. 7
·期 6
·2855-2861
·
IF 1.821
Zhuo Ye,Lingxi Yang,Jianguo Wen,Baoxian Ye
A novel voltammetric sensor, based on a single-walled carbon nanotube (SWNT) composite poly(L-serine) film modified electrode, was fabricated by simple dipping–drying and electrodeposition methods and used for highly sensitive determination of natamycin. At this sensor, the electrochemical response of natamycin was improved greatly due to the synergistic effect of SWNTs and poly(L-serine). A new voltammetric method for the determination of natamycin was proposed with a detection linear range of 6 × 10−8 mol L−1 to 6 × 10−6 mol L−1 and a detection limit of 4 × 10−8 mol L−1. Furthermore, the electrode reaction of natamycin was investigated in detail and some dynamic parameters were calculated for the first time. Using the present method, the residual quantity of natamycin in available claret and beverage samples was evaluated with good satisfactory recovery.
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MOLECULES
·
2025
·Vol. 30
·期 5
·998
·
IF 4.6
Yuanqi Duan,Jinfeng Sun,Yongkang Xue,Weiwei Xu,Yuxin Jiang,Tieqiang Zong,Wei Zhou,Zhengyu Hu,Gao Li
Given that the preparation method of polysaccharides affects the functional properties, four types of acidic polysaccharides (BCP30-1a, BCP50-1a, BCP70-1a, and BCP90-1a) were prepared using the gradient ethanol precipitation method. Then, a series of chemical and instrumental analysis techniques were used to compare structural characteristics and morphology. Neuroprotective effects were explored using OGD/R-induced PC12 cells. The results showed that BCP30-1a, BCP50-1a, BCP70-1a, and BCP90-1a had similar characteristic groups and contained both β-glycosidic and α-glycosidic bonds. Their molecular weights, in descending order, were 198.398 kDa, 184.690 kDa, 184.556 kDa, and 184.217 kDa, respectively. In addition, the four polysaccharides contained different proportions of glycosidic bonds, namely, Manp-(1→, →5)-Araf-(1→, →3)-Galp(or GalAp)-(1→, →4)-Glcp-(1→ and →3,6)-Galp-(1→. BCP30-1a also contained a certain proportion of Galp-(1→, and each polysaccharide had different microscopic characteristics and good thermal stability. Finally, BCP50-1a, BCP70-1a, and BCP90-1a exhibited good cytoprotective effects on PC12 cells based on the OGD/R model. These findings provide a novel regulatory strategy for the functional activity of BCPs and offer scientific evidence supporting application in the research field of ischemic stroke.
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