Journal of Nanomaterials
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2023
·
IF 3.791
Shengyan Pu,Wenwen Wu,Dongsheng Shi,Yanqi Dai,Jun Zhang,Mingyan Zhao,Shuangyu Liu,Guihong Zheng,Xingqi Wang,Yu Yan,Jun Xie
Realgar, a traditional Chinese medicine, has notable antitumor activity and can be used in various hematologic tumor and solid tumor therapies in a wide range of clinical applications. Nanosized realgar possesses higher surface activity and enhanced therapeutic effects on cancer cells compared with those of bulk realgar. In this study, we reported the design of high-performance nanorealgar quantum dots (NR QDs) with aggregation-induced emission enhancement of crystal units (CUs) with the addition of hydrochloric acid. The enhanced fluorescence characteristics of NR QDs are associated with an optimized crystal structure obtained by accelerating the growth process of NR CUs in which the smaller NR CUs facilitate a self-assembling arrangement and a complete structural optimization process, ultimately forming regular crystallization with a size quantization effect. To improve the theranostic efficiency of NR QDs, we synthesized NR QDs coupled with a tripeptide of arginine–glycine–aspartic acid (RGD) with tumor neovascular targeting. We intravenously injected [email protected] QDs into BALB/c mice bearing a subcutaneously transplanted breast tumor (4T1). Our results indicate that functional [email protected] QDs are effective chemotherapeutic drugs that can anchor into the tumor endothelial cells through an active targeting effect, inhibit the angiogenesis in the tumor, and eventually “cut-off” the nutrient-rich blood supply to the tumor. This promising antiangiogenesis therapeutic strategy induces [email protected] QDs to penetrate tumor-fenestrated vascular networks and has potential clinical value.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2022
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IF 6.371
Xinqi Chen,Wenjing Lv,Zhili Shi,Pujia Cheng,Kaidong Zhan,Yaqi Liu,Fan Wu,Quinn Qiao
The photovoltaic conversion of heterojunction solar cells relies on the interface properties between n-type and p-type semiconductors. N-type TiO 2 -nanoarray (NA), ferroelectric BiFeO 3 interlayer, and p-type BiOI were used to fabricate a ternary bulk heterojunction using a solution-based method in this study. Solid-state solar cells of FTO/TiO 2 -NA/BiFeO 3 /BiOI/spiro-OMeTAD/Ag are constructed for the first time, and their photo-electric conversion performance is studied. The addition of a BiFeO 3 interlayer at the interface between TiO 2 -NA and BiOI increased the solar cell open-circuit voltage ( V oc ) from 0.18 to 0.47 V and the short-circuit current ( J sc ) from 0.29 to 0.54 μA/cm 2 , resulting in a nearly 5-fold increase in power conversion efficiency. The Kelvin Probe force microscope analysis confirmed that the polarization electric-field ( E self ) generated by the BiFeO 3 interlayer is directed toward BiOI, thereby increasing the surface potential and decreasing electron and hole back flows between TiO 2 and BiOI. This additional electric field caused greater charge concentrations and a greater V oc . Furthermore, the E self directed toward the BiOI increased the built-in electric field ( E bi ) in the space charge area from TiO 2 to BiOI, allowing for greater separation of photogenerated electrons and holes and thus raising the J sc . The findings of this study suggested that manipulating internal electric fields via polarization could be an effective method for enhancing the performance of solar cells based on BiOI.
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MATERIALS RESEARCH BULLETIN
·
2023
·
IF 5.4
Dongfang Lv,Jingchuang Han,Zhaowu Li,Jie Xiong,Pingfan Du,Lixin Song
Inorganic hole transport materials (HTMs) play an important role for the stability and efficiency of planar perovskite solar cells (PSCs). Among the numerous inorganic HTMs, NiCo 2 O 4 with its excellent performance is the emerging candidate for hole transport layers (HTLs) and is attracting increasing attention. However, the low electrical conductivity and optical transmittance of NiCo 2 O 4 severely limit the device performance. Herein, the Zn 2+ was used to dope NiCo 2 O 4 to improve the electrical conductivity and optical transmittance of NiCo 2 O 4 . And the effects of the concentration of Zn 2+ on the morphology, structure and properties of NiCo 2 O 4 were investigated. The morphology and transparency of Zn x Ni 1-x Co 2 O 4 would not be affected when the concentration of Zn 2+ is below 0.1, but when it is up to 0.15 and 0.2, the morphology of NiCo 2 O 4 clustered together or showed a diamond-shaped block, and the optical transmittance also decreased significantly. Meanwhile, with the increase of doping amount, the conductivity and hole mobility are gradually increased. As a result, the optimal concentration of Zn 2+ is 0.1. Besides, the Zn 0.1 Ni 0.9 Co 2 O 4 possessed a significant improvement in hole extraction and better band alignment compared to the NiCo 2 O 4. And hence, the power conversion efficiency (PCE) of PSCs fabricated in open air is up to 13.41% by using Zn 0.1 Ni 0.9 Co 2 O 4 . This work develops a potential strategy for developing highly efficient and stable PSCs, opens up a new horizon for the development of inorganic HTMs.
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Small
·
2022
·Vol. 18
·期 51
·2203571
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IF 15.153
Tingting Zhu,Kun Zhang,Chengmin Ji,Xinyuan Zhang,Huang Ye,Yuanchen Zou,Junhua Luo
Multilayered chiral hybrid perovskites are highly desired for highly-sensitive circularly polarized light (CPL) detection rooted in their efficient charge transport and strong chiroptical activity. However, designing multilayered chiral hybrid perovskites remains a huge challenge. Here, through pairing achiral ethylamine (EA)−chiral arylamine in the interlayer space, multilayered chiral alternating cations intercalation-type (ACI) hybrid perovskites (R-/S-PPA) EA 2 Pb 2 Br 7 (PPA = 1-phenylpropylamine) are successfully obtained. Significantly, perovskitizer EA extends the thickness of the quantum well and alternating space cation EA greatly alleviates in-plane tilting distortions of adjacent metal halide octahedra, providing fast channels for in-plane carrier transport. Consequently, single-crystal photodetectors of (R-/S-PPA) EA 2 Pb 2 Br 7 exhibit high circular polarization sensitivity with a large anisotropy factor of 0.3, which falls around the highest value among the layered hybrid perovskites. In addition, a fast responding rate (τ r )of 308 µs and a high CPL-detectivity of 8 × 10 12 Jones are also presented. This work opens up a new perspective to design multilayered chiral hybrid perovskites for high-sensitive CPL detection.
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高影响因子
ENERGY
·
2022
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IF 8.857
Feng Chen,Yuhao Zhang,Liang Zhao,Jinsen Gao,Pengfei Hao,Qingfei Meng,Chunming Xu
Simulations can effectively and accurately determine optimal process conditions without extensive experiments in the desulfurization of fluid catalytic cracking (FCC) naphtha by extractive distillation . The UNIFAC-original model in Aspen Plus v8.8 is suitable for simulating the process with several components. However, the lack of group binary interaction parameters between the solvent and sulfides in FCC naphtha reduced the accuracy of the UNIFAC-original model in Aspen Plus v8.8. Consequently, the required group binary interaction parameters were calculated using binary vapor–liquid equilibrium (VLE) for improved accuracy. The obtained VLE data were thermodynamically consistent. The empty group binary interaction parameters were calculated using the VLE data. An accurate simulation method was obtained for the desulfurization of FCC naphtha using these parameters, and the absolute deviation between the simulated and experimental results was 0.4 wt%. Subsequently, sensitivity analysis was performed to obtain the optimal process conditions. The experimental results correlated well with the simulation results, thereby proving that the parameters were regulated and that the simulation demonstrated high accuracy. Moreover, the sulfur content in the raffinate could be decreased to 4.37 mg/kg. Thus, refineries can rapidly establish their optimal process conditions through simulation.
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ADVANCED FUNCTIONAL MATERIALS
·
2022
·Vol. 32
·期 31
·2201081
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IF 19.924
Qiqi Mao,Kai Deng,Hongjie Yu,You Xu,Ziqiang Wang,Xiaonian Li,Liang Wang,Hongjing Wang
Designing efficient and durable electrocatalysts for seawater electrolysis shows a great research prospect, but it remains a significant challenge. Herein, we report the partially hydroxylated Rh metallene (Rh/RhOOH metallene) with porous, ultrathin, defect-rich and hetero-phase structure for ethylene glycol (EG)-assisted seawater electrolysis. In parallel, the unique redox effect of RhOOH species and EG as well as the electroreduction effect riggers the in situ reconstruction for the catalyst during electrocatalysis, which further produces active Rh species to optimize the catalytic activity center and surface catalytic reaction. Benefiting from the unique metallene structure and the Rh/RhOOH heterogeneous structure, the Rh/RhOOH metallene exhibits superior electrocatalytic performance towards hydrogen evolution reaction (HER, overpotential of 29 mV) and EG oxidation reaction (EGOR, specific activity of 1.051 mA cm –2 ). Encouragingly, in the constructed EG-assisted seawater electrolysis system, the Rh/RhOOH metallene only needs a low cell voltage of 0.678 V to achieve a current density of 10 mA cm –2 for energy-saving H 2 production, which significantly reduces energy consumption compared to conventional seawater electrolysis.
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Acta Pharmaceutica Sinica B
·
2022
·
IF 14.903
Zhejie Chen,Wei Hao,Caifang Gao,Yangyang Zhou,Chen Zhang,Jinming Zhang,Ruibing Wang,Yitao Wang,Shengpeng Wang
With the development of synthesis technology, modified messenger RNA (mRNA) has emerged as a novel category of therapeutic agents for a broad of diseases. However, effective intracellular delivery of mRNA remains challenging, especially for its sensitivity to enzymatic degradation. Here, we propose a polyphenol-assisted handy delivery strategy for efficient in vivo delivery of IL-10 mRNA. IL-10 mRNA binds to polyphenol ellagic acid through supramolecular binding to yield a negatively charged core, followed by complexing with linear polyetherimide and coating with bilirubin-modified hyaluronic acid to obtain a layer-by-layer nanostructure. The nanostructure specifically up-regulated the level of IL-10, effectively inhibited the expression of inflammatory factors, promoted mucosal repair, protected colonic epithelial cells against apoptosis, and exerted potent therapeutic efficacy in dextran sulfate sodium salt-induced acute and chronic murine models of colitis. The designed delivery system without systemic toxicity has the potential to facilitate the development of a promising platform for mRNA delivery in ulcerative colitis treatment.
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高影响因子
Journal of Physical Chemistry C
·
2022
·
IF 4.177
Zhuangzhuang Zhang,Shining Geng,Jiaoxia Zhang,Zilong Zhang,Qiu Xiong,Lusheng Liang,Ruixiang Mi,Zewen Xiao,Rosario Scopelliti,Peng Gao
We present a homologous series (CH3(NH2)2)2PbX4 (X = Cl, Br, I) of the Ruddlesden–Popper two-dimensional (2D) perovskite series. The new A-site cation (methyl hydrazinium, MHy) stemming from an atomic permutation of formamidine shows unique hydrogen-bond-stabilized 2D structures contrasting ethyl amine (CH3CH2NH3) and formamidine (NHCHNH2) as revealed by single-crystal X-ray diffraction. The subtle manipulation of the tolerance factor leads to (CH3(NH2)2)2PbX4 with the smallest interlayer spacing among the reported R–P 2D perovskites. A combined density functional theory calculation and experimental study assist in interpreting these disparate (electronic) structures/properties brought by similar cations. First-principles calculations also confirm the direct bandgap nature of (CH3(NH2)2)2PbI4 with wide valence and conduction bandwidths. After studying different colloidal behavior in the common polar solvents, we continued with the characterization based on the thin film samples. The homologous series (CH3(NH2)2)(CH3NH3)nPbnI3n+1 (n = 1, 2, 3, 4) multidimensional (MD) perovskite films show a characteristic decrease of the bandgap as n increases. The potential of these MD perovskites toward planar junction solar cell applications was assessed, and an initial power conversion efficiency of 5.83% was obtained from the (CH3(NH2)2)2(CH3NH3)3Pb4I13 perovskite, with reasonable stability after aging for 1200 h. This new cation provides new chances for many more homologous 2D halide perovskites for solid-state photovoltaics and other applications.
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CHEMICAL ENGINEERING JOURNAL
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2022
·
IF 16.744
Zizhao Qian,Yuanxiang Xiao,Xujun Zhang,Qing Li,Lujie Wang,Feiya Fu,Hongyan Diao,Xiangdong Liu
Bisphenol A (BPA) is the main precursor in the synthesis of epoxy resins. However, because of its toxic and nonrenewable nature, BPA is unsuitable in the sustainable preparation of epoxy resins. In contrast, Diphenolic acid (DPA) is renewable but its carboxyl group limits its applications in bio-based thermosets. In this study, we report a novel amidation route to tailor DPA to produce epoxide monomers that present epoxy resins with a high performance. The diphenolic amides exhibited very low toxicities when compared with that of BPA, and also provided an unexpected autocatalytic effect on the curing reactions when succinic anhydride (SA) was used as the hardener. Dynamic mechanical analyses (DMA) and tensile test results confirmed the remarkable thermomechanical properties of the cured epoxy resins, which may be attributed to the increased cross-linking density and enhanced hydrogen bonding by the amide groups. Among the SA-cured epoxy resins, diglycidyl ether of diphenolic ethylamide exhibited the best performance, which included a high T g of 114 °C, char yield (CY) of 20%, tensile strength of 60.2 MPa, and toughness value of 185 MPa. In addition, the DPA-derived epoxy resins have great potential in the preparation of bio-based composites because they act as excellent interfaces between the resin and cotton fibers (CoFs). Our study presents a new strategy to prepare bio-based epoxy resins with a high performance, emphasizing the greater potential of amidated DPA derivatives to replace BPA in the epoxy resin market.
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ACS Sustainable Chemistry & Engineering
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2022
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IF 9.224
Xiaoyan Pei,Zhiyong Li,Huiyong Wang,Qiuju Zhou,Zuodong Liu,Jianji Wang
Surfactant-free microemulsions (SFMEs) have shown great potential in many aspects such as chemical reactions and material preparation. Ionic liquid (IL)-based SFME is a promising member in this family. However, switchable phase separation of nonaqueous IL SFMEs has not been reported up to now although it is of great importance for the separation of products and recycling of the systems. Herein, a new kind of CO2-responsive SFMEs composed of quaternary ammonium IL, dimethyl sulfoxide, and ethyl acetate has been developed. It is worth noting that the microemulsion can be reversibly switched between emulsification and complete phase separation upon alternative CO2 and N2 bubbling at atmospheric pressure. The microstructures and phase behavior of the systems before and after CO2 bubbling have been systematically studied by phase diagrams, electrical conductivity, dynamic light scattering, optical microscopy, and atomic force microscopy, respectively. Mechanism studies verify that the reversible switching is attributed to the generation and restoration of more hydrophilic carbamate salts from the reaction of CO2 with IL anions, which results in poor solubility of ILs in the nonaqueous microemulsions and thus reversible breaking and rebuilding of the microemulsions. Based on this unique phase behavior, the CO2-switchable SFMEs are used as a microreactor for room temperature synthesis of Zn-based metal–organic frameworks, and effective reaction and microemulsion recycling have been achieved. This study may provide a new strategy for the integration of reaction, separation, and recycling procedures to obtain sustainable chemical processes.
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ACS Applied Materials & Interfaces
·
2022
·
IF 10.383
Wei Shen,Ye Yu,Wenzhu Zhang,Yanfeng Chen,Jianbin Zhang,Liu Yang,Jingting Feng,Gang Cheng,Lihui Liu,Shufen Chen
Exploitation of next-generation blue light-emitting diodes (LEDs) is the foundation of the revolution in lighting and display devices. Development of high-performance blue perovskite LEDs is still challenging. Herein, 4-aminobenzenesulfonic acid (SA) is introduced to passivate blue CsPbBr3 nanoplates (NPLs), reducing the ionic migration via a more stable Pb2+–SO3–– formation, and the trap state density of films shows a 50% reduction. The inevitable Br– vacancy defects after the multistep washing process can be suppressed by a suitable MABr treatment, which can boost the external quantum efficiency (EQE) performance. It should be noted that the coverage of NPL films is another key factor to realize reproducible pure blue electroluminescence (EL). Therefore, we proposed an alternate droplet/spin coating method to improve the coverage and thickness of NPL layer to prevent hole transport layer emission and increase the reproducibility of LED performance and spectra. Furthermore, we designed hole transport layers to decrease the hole transport barrier and improve the energy-level alignment. According to SA passivation, MABr treatment, alternate droplet/spin coating method, and device structure optimization, a CsPbBr3 NPL-based pure blue (0.138, 0.046) LED with 3.18% maximum EQE can be achieved, and the half-lifetime of EL can be enhanced 1.71 times as compared to that of the counterpart LED without SA. Both performance and stability of pure blue NPL LEDs can be greatly improved via ligand passivation, alternate droplet/spin coating method, and device structure optimization, which is a trend to promote the development of pure blue perovskite LEDs in future.
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INDUSTRIAL CROPS AND PRODUCTS
·
2021
·
IF 5.645
Wei Li,Qian Liu,Xuedong Cheng,Zhenzhen Xu
The main objective of this study was to reveal the superiority of new amphipathic poly(sodium allyl sulfonate) (PSAS)/poly(ethyl acrylate) (PEA) structure to control P(SAS- co -EA) structure in adhesion to cotton fibers and film properties. Another objective was to explore the effect of the grafting ratios of poly(sodium allyl sulfonate)- g -starch- g -poly(ethyl acrylate) (PSAS- g -S- g -PEA) samples on the properties, so as to provide a new starch-based adhesive for cotton warp sizing. A series of PSAS- g -S- g -PEA samples and control S- g -P(SAS- co -EA) samples were prepared, and their adhesion to cotton fibers and film properties were evaluated. The PSAS- g -S- g -PEA samples with grafting ratios of 11.33% and 9.02% showed bonding strengths of 17.54 cN/tex and 17.01 cN/tex, and their film possessed elongations at break of 4.89% and 4.53%, and bending endurances of 2000 cycles and 1598 cycles, respectively. In contrast, the S- g -P(SAS- co -EA) samples with the ratios of 10.34% and 7.98% had bonding strengths of 16.33 cN/tex and 15.91 cN/tex, and their films showed elongations at break of 4.31% and 3.95%, and bending endurances of 1541 cycles and 1323 cycles, respectively. Therefore, the combination of the PSAS and PEA branches exhibited obvious superiority in the properties to P(SAS- co -EA) structure. Increasing the grafting ratios from 0% to 11.33% could increase the bonding strength from 14.92 cN/tex to 17.54 cN/tex and elongation at break from 2.58% to 4.89%, enhance bending endurance from 1075 cycles to 2000 cycles, and reduce film strength from 38.21 MPa to 32.02 MPa. PSAS- g -S- g -PEA as a new adhesive showed potential application for sizing cotton warps.
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