CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Mifa Chen,Yefei Wang,Wuhua Chen,Mingchen Ding,Zhenyu Zhang,Chuhan Zhang,Shizhang Cui
Functional polymers play an increasingly significant role in oilfield development. Herein, the side-chain functionalized copolymer APVR was fabricated using functional monomer 2,6-bis(1-methyl-1H-benzo[d]imidazol-2-yl)pyridin-4-yl-methacrylate (BMP) with similar structure to the heavy components in crude oil and di-hexadecanol maleate (DHM) with long alkyl chain. 1 H NMR, FTIR and TGA analyses were employed to characterize the structure of APVR. Simultaneously, viscosity reduction performance and heavy oil displacement performance of APVR were also studied. For comparison, the copolymers P(AAB), P(AAD) and P(AA) containing one functional monomer and without functional monomer were also synthesized. The results showed that when the copolymer concentration is 2000 mg/L, the viscosity reduction rate (VRR) of APVR, P(AAB), P(AAD) and P(AA) is 93.1%, 84.3%, 82.4% and 65.4%, respectively. Furthermore, compared with water flooding, their ultimate recovery of heavy oil increased by 18.34%, 13.78%, 13.18% and 9.93%. The interaction mechanisms between APVR and heavy oil were studied using XRD, SEM, and molecular dynamic simulation. Due to their unique structure, BMP and DHM were able to permeate into the molecule structures of heavy oil, reducing the intermolecular forces between heavy components by forming supramolecular forces with asphaltene. Thus, they led to the loose stacking of asphaltene aggregates, making it easier for APVR to emulsify oil droplets due to its amphiphilic property. The copolymer APVR shows promising potential for reducing heavy oil viscosity and may have broad application prospects in heavy oil exploitation.
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Journal of Energy Storage
·
2023
·
IF 9.4
Qiang Yao,Jing Guo,Yuanfa Liu,Fucheng Guan,Shuxing Liu,Xuelin Huang,Xin Zhang,Qiang Yang
In this work, an organic phase change material-Bishexadecyl maleate was prepared by direct esterification of maleic anhydride (MA) and hexadecanol (HD). Then, in order to improve the crystalline phase of bishexadecyl maleate (MAHD), the synthesized MAHD was recrystallized with ethanol to prepare ethanol-bishexadecyl maleate (MAHD (E) ). Fourier transform infrared spectroscopy (FTIR), nuclear magnetic resonance (NMR), and x-ray diffraction (XRD) were used to characterize the chemical and crystalline structures of MAHD and MAHD (E) . Polarizing Light Microscopy (POM) for observation of phase transition behavior of MAHD/MAHD (E) . Differential scanning calorimetry (DSC), Variable temperature Fourier transform infrared spectroscopy (VT-FTIR), and thermo gravimetric analysis (TG) characterize the thermal properties and thermal stability of MAHD/MAHD (E) . The results display that MAHD/MAHD (E) have the same chemical structure, and no chemical change occurs within the phase transition temperature, but the crystallinity of MAHD (E) has increased. Compared with HD, the crystallization temperature and melting temperature of MAHD/MAHD (E) is significantly reduced, which effectively expands the application range of HD. POM was observed to have a melting-recrystallization-melting behavior during the heating of MAHD/MAHD (E) . This behavior was shown in the DSC curve as an unusual endothermic-exothermic-endothermic curve. After 100 thermal cycles, both MAHD and MAHD (E) exhibit good cycling stability. TG exhibits that the thermal stability of MAHD/MAHD (E) has been dramatically improved compared to HD, it has high application potential in phase change and energy storage. Therefore, MAHD/MAHD (E) is expected to be a substrate for new phase change materials , while the C C in the molecular chain provides potential reactivity with significant potential applications in the field of phase change energy storage.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2023
·
IF 5.2
Yuyan Yang,Shaowei Yan,Bin Yu,Chang Gao,Kuan Chang,Jing Wang
Emulsion systems are widely used as carriers for diverse actives processing moisturizing, anti-aging, whitening and other functions. Recently, emulsions containing lamellar gel phase have been attracting more and more research interests since it improves the physical stability of degradable actives. In the present work, o/w emulsions containing lamellar gel phase composed of ceteareth-20 (O-20) and mixed fatty alcohols (FA) were developed for retinyl propionate (RP) stabilization and transdermal delivery . The lamellar gel phase was confirmed by XRD combined with cryo-SEM, and main factors for lamellar gel phase formation were investigated and discussed. Moreover, effects of carrier oil on the emulsion properties were studied and the result showed that introduction of carrier oil benefits RP retention, rheological and transdermal properties. This study proves that O-20/FA based lamellar phase emulsion is promising system for RP stabilization and utilization in cosmetic formulations.
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Advanced Science
·
2022
·Vol. 9
·期 27
·2202744
·
IF 17.521
Songtao Dong,Yuan Zhang,Xiangnan Guo,Chuang Zhang,Zhaomeng Wang,Jiang Yu,Yubo Liu,Chang Li,Yuting Hu,Bingjun Sun,Mengchi Sun,Haotian Zhang,Defang Ouyang,Zhonggui He,Yongjun Wang
Spatiotemporal delivery of nanoparticles (NPs) at the “cellular level” is critical for nanomedicine, which is expected to deliver as much cytotoxic drug into cancer cells as possible when NPs accumulate in tumors. However, macrophages and cancer-associated fibroblasts (CAFs) that are present within tumors limit the efficiency of spatiotemporal delivery. To overcome this limitation, glutathion pulse therapy is designed to promote reduction-sensitive Larotaxel (LTX) prodrug NPs to escape the phagocytosis of macrophages and penetrate through the stromal barrier established by CAFs in the murine triple negative breast cancer model. This therapy improves the penetration of NPs in tumor tissues as well as the accumulation of LTX in cancer cells, and remodels the immunosuppressive microenvironment to synergize PD-1 blockade therapy. More importantly, a method is established that can directly observe the biodistribution of NPs between different cells in vivo to accurately quantify the target drugs accumulated in these cells, thereby advancing the spatiotemporal delivery research of NPs at the “cellular level.”
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PubMed
高影响因子
JOURNAL OF SURFACTANTS AND DETERGENTS
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2022
·Vol. 25
·期 5
·643-654
·
IF 1.972
Yu Zhao,Chenyu Liu,Hailiang Chen,Hengjun Zhou,Simiao Yu,Deze Mi,Shuli Yue,Weihong Qiao
Liposomes are the predominant drug delivery system widely used in the pharmaceutical industry, but rapid clearance and endosome degradation are the main barriers to improve the delivery efficiency of liposomes, especially for protein or genes. Simulating viral membrane fusion peptides, four asymmetrically dihydrophobic chain polyethylene glycol (PEG) lipids with long circulating and membrane fusion properties have been designed and synthesized with a high yield. The structure of synthetic PEG lipids is characterized by 1 H NMR and mass spectrometry. The critical micelle concentrations of PEG lipids are lower by one or two orders of magnitude compared with traditional surfactants such as SDBS or SDS, which show excellent self-assembly performance of lipids. The size and morphology of liposomes constituted with neutral lipid DOPC and PEG lipid are characterized by dynamic light scattering (DLS) and transmission electron microscopy (TEM). In the conditions of 50% ethanol and 5–25 mmol L −1 Ca 2+ , the PEG neutral lipid complexes encapsulated pEGFP are almost neutral with a diameter below 300 nm.
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FUEL
·
2022
·
IF 8.035
Lin Fu,Zhaoxin Liu,Xin Li,Yongfei Li,Houyi Yang,Yuejin Liu
Ni-catalysts usually experienced quick deactivation during bio-lipids deoxygenation due to metal sintering and coke. Here we prepared a series of Ni/CeO 2 -Al 2 O 3 catalysts, denoted as NiCeAl-EISA, NiCeAl-WI and NiCeAl-CP, prepared by evaporation-induced self-assembly (EISA), wetness impregnation (WI), co-precipitation (CP) methods, respectively, aiming at tuning metal-support interaction (MSI) in Ni/CeO 2 -Al 2 O 3 catalysts for the deoxygenation of bio-lipids to hydrocarbons. The porosity and surface properties of the catalysts are systematically studied by BET, XRD, H 2 -TPR, HR-TEM, FT-IR, O 2 -TPD, NH 3 -TPD, RPR, Py-FTIR, XPS and in situ XPS. The NiCeAl-EISA catalyst afforded 92.2% n-C 11 yield at full methyl laurate conversion, and efficiently deoxygenated different FAMEs, yielding corresponding alkanes yields of 97.8% (n-C 9 ), 96.4% (n-C 13 ), 94.3% (n-C 15 ) and 92.9% (n-C 17 ). The TOFs were calculated as 426–719, 241–343 and 148–243 h −1 for NiCeAl-EISA, NiCeAl-WI and NiCeAl-CP catalysts, respectively. Jatropha oil and waste cooking oil were also converted into liquid alkanes (C 13-18 ) with a total yield of 95.4% and 93.7%, respectively. The NiCeAl-EISA catalyst exhibits superior catalytic activity and remained stable with 92.2% n-C 11 yield after 11 consecutive runs, as compared with NiCeAl-WI and NiCeAl-CP. This significant increase in catalyst activity and stability is closely correlated with the tunable SMSI of Ni/CeO 2 -Al 2 O 3 catalyst, which facilely forms abundant oxygen vacancies and interfacial sites (Ni δ+ -O V -CeO x ). This suppresses strong Ni-Al interaction, thus exposing more active and robust Ni sites to promote R-COOH → R-CHO reduction to produce more alkanes. The weakened Ni-Al interaction also reduces the strong acidity and consequently inhibits the coke formation and simultaneously restrains C–C bond cleavage of hydrocarbons.
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高影响因子
COMPOSITES PART B-ENGINEERING
·
2022
·
IF 11.322
Weijuan Zou,Longchen Wang,Junnian Hao,Lixian Jiang,Wenxian Du,Tao Ying,Xiaojun Cai,Haitao Ran,Jianrong Wu,Yuanyi Zheng
Insufficient concentrations of intracellular substrates such as hypoxia and H 2 O 2 considerably reduce the effectiveness of reactive oxygen species (ROS)-associated cancer therapy. Modulating the tumor microenvironment (TME) for augmenting efficacy has become a promising strategy. Herein, a phase-change cascaded nanomedicine (Lap-IrO x @PCM) was constructed via co-encapsulation of iridium oxide nanozyme (IrO x ) and β-lapachone (Lap) by using thermal-responsive phase-change materials (PCMs). After photothermal activation, the protective PCM layer was melted, causing the rapid release of IrO x and Lap. Simultaneously, the peroxidase-like nanozyme IrO x reacted with endogenous H 2 O 2 to liberate highly toxic hydroxyl radicals (•OH) for inducing tumor cell death. Meanwhile, IrO x as another glutathione peroxidase nanozyme also consumed glutathione (GSH) to protect ROS from scavenging. Importantly, the released Lap efficiently generated H 2 O 2 for facilitating the catalytic efficacy of IrO x and provoke the cleavage of heat shock protein 90 (Hsp90) for overcoming tumor heat tolerance in photothermal therapy (PTT). As systematically demonstrated both in vitro and in vivo , this well-defined system achieved a superior antitumor effect via mild photothermal-enhanced nanocatalytic therapy. Our findings have provided the proof of concept of the phase change-mediated, in vivo catalytic activity of nanozymes that can be customized for intensive, TME-mediated, self-enhanced nanocatalytic cancer therapy.
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FUEL
·
2021
·
IF 6.609
Jinlei Chen,Dechao Wang,Fenqiang Luo,Xinyu Yang,Xingyong Li,Shuirong Li,Yueyuan Ye,Duo Wang,Zhifeng Zheng
Production of valuable chemicals and fuels from waste animal fat and vegetable oils can serve as alternatives to fossil energy. In this study, the selective production of alkanes and higher fatty alcohol via hydrodeoxygenation (HDO) of palmitic acid over red mud-supported nickel catalysts (Ni/RM) was reported. Meanwhile, the study has investigated the effect of Ni loading, reaction temperature, hydrogen pressure on the HDO of palmitic acid, analyzed the reusability of Ni/RM and explored the possible reaction mechanism. The results show that palmitic acid is completely converted over 7%Ni/RM. The selectivity of fatty alcohol and alkanes are 92.54% (260 °C) and 100% (300 °C), respectively. Ni/RM has shown the highest catalytic performance as compared to commercial Ni/SiO 2 and Ni/γ-Al 2 O 3 catalysts. The 7%Ni/RM also demonstrates stable catalytic performance after multiple times of reuse. Moreover, hexadecanol plays an important role in hydrodeoxygenation, decarbonylation, and decarboxylation routes.
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Catalysts
·
2021
·Vol. 11
·期 12
·1471
·
IF 4.146
Zhenzhen Li,Wei Liu,Guolong Yang
Synthesized oleic acid-based wax esters (e.g., cetyl oleate), which can replace spermaceti oil or jojoba oil, have been widely used in the cosmetic, pharmaceutical and other industries. In this work, 4-dodecylbenzenesulfonic acid (DBSA) has been successfully used as an efficient catalyst to synthesize oleic acid-based wax esters through esterification at 40 °C under solvent-free conditions. A 93.6% conversion rate of cetyl alcohol was obtained under optimal conditions: 10 mol% DBSA, a molar ratio of 1.3:1 oleic acid to alcohol, a reaction temperature 40 °C and a reaction time of 4 h. The effect of water content on esterification was investigated, and it was found that the inhibitory effect of water decreased significantly with increasing temperature. Moreover, DBSA-catalyzed esterification could be applied in the production of various oleic acid-based wax esters and excellent conversion (>90%) to esters was obtained under such mild conditions. DBSA-catalyzed low-temperature esterification is an efficient method for the production of liquid wax esters.Keywords:liquid wax esters;4-dodecylbenzenesulfonic acid;esterification;oleic acid;high-oleic sunflower seed oil
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Polymers
·
2021
·Vol. 13
·期 23
·4096
·
IF 4.329
Lin Wang,Yanqiang Ni,Xin Qi,Liqun Zhang,Dongmei Yue
Hydrogenated Nitrile Rubber (HNBR) is widely used in aerospace, petroleum exploration and other fields because of its excellent performances. However, there remains a challenge of balancing the oil resistance and the low temperature resistance for HNBR. In this work, a series of grafted carboxyl nitrile rubber (XNBR) was prepared by the esterification reaction between active functional groups (–COOH) of XNBR and alkanols of different molecular chain lengths (C8H17OH, C12H25OH, C16H33OH, C18H37OH) or Methoxypolyethylene glycols (MPEG) of different molecular weights (Mn = 350, 750, 1000). The structure and low temperature resistance of as-obtained grafted polymers were characterized by Fourier Transform Infrared (FTIR),1H-NMR and Differential scanning calorimetry (DSC). It was found that the glass transition temperatures (Tg) of grafted XNBR were significantly decreased. MPEG grafted polymers with better low temperature resistance were then selected for hydrogenation. As-prepared hydrogenated XNBR grafted with MPEG-1000 (HXNBR-g-1000) showed the lowest Tgof −29.8 °C and the best low temperature resistance. This work provides a novel and simple preparation method for low temperature resistant HNBR, which might be used potentially in extremely cold environments.Keywords:hydrogenated nitrile rubber (HNBR);grafting;low temperature resistance
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PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Pan-Pan Zhao,Cong Deng,Ze-Yong Zhao,Le Wan,Chi Huang,Yu-Zhong Wang
Hydrocarbon-based phase change materials (PCMs) are accompanied by an inherent fire risk, which is hindering their further application especially in construction. Molecular-firefighting PCMs can be ideal and promising candidates to simultaneously ensure the highly efficient energy management and fire safety of PCMs. In this work, two novel phosphorus/nitrogen-containing ionic liquids ([DP][MI] and [DP][TEA]), composed of imidazole (MI) or triethylamine (TEA) cations and dicetyl phosphate (DP) anion, were synthesized for fire-proofing thermal energy management. The fire risk assessment confirmed that the extinguishing time of prepared [DP][MI] and [DP][TEA] was greatly shortened to 20 s and 3.5 min from 45 min for controlled sample, respectively. Moreover, the thermal enthalpy of [DP][MI] reached about 99.0 J g–1. In addition, [DP][MI] and [DP][TEA] achieved low supercooling extents of 2.2 and 4.4 °C, separately. Both molecular firefighting and efficient energy management were achieved for [DP][MI] and [DP][TEA]. As applied in wood-plastic composite which is ubiquitous in construction, [DP][TEA] endowed the composite with temperature-regulating capability of about 10 °C in hut test and remarkably suppressed fire hazard of the composite, displaying a potential application value.
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JOURNAL OF MOLECULAR LIQUIDS
·
2023
·
IF 6
Guoqing Zhang,Yancheng Zheng,Fuquan Tian,Hai Liu,Xiaobing Lu,Xiao Yi,Zhengliang Wang
Carboxy betaines CnZC (where n represents the carbon number of the alkyl chain, n = 12,14 and 16) and extended surfactant C16P3E6S were combined to assess their potential application for enhanced oil recovery (EOR) by investigating the surface properties, interfacial properties and emulsifications of the single and compounded surfactants. The results demonstrated that four surfactants with favorable water solubility exhibited better surface properties. Among them, the mixture of betaine surfactant C14ZC and sulfonate surfactant C16P3E6S displayed a synergistic effect in reducing interfacial tension (IFT). The solution with C14ZC mole fractions of 60 % and 50 % possessed an ultra-low IFT (10 -3 mN/m order of magnitude) at 10 % NaCl whose emulsification rates of oil in brine for mixtures exceeded 90 % at 4 % NaCl. Notably, the emulsion droplet diameter was smaller compared to other salinity conditions, indicating that the combination of C16P3E6S and C14ZC enhanced emulsion stability, correspondingly ultra-low IFTs at both the oil-emulsion and emulsion-water interfaces. Coreflooding experiments revealed that the depressurization rate for the optimized surfactant system (with a molar fraction of C16P3E6S/C14ZC = 2:3) with superior emulsification properties, effectively abilities of reduced IFT, increased capillary number and lower adsorption loss was 26.7 % and its EOR was 20.4 %, confirming its favorable displacement performance and potential application in medium to high salinity reservoirs.
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危险品化学品经营许可证（带存储）