MICROCHEMICAL JOURNAL
·
2026
·
IF 5.2
Liang Guo,Huifang Li,Xiaoying Wang,Yuzhen Jia,Huaixia Yang,Xiaoke Zheng
Acetamiprid (ACE), a typical neonicotinoid pesticide, has raised significant environmental and food safety concerns due to its persistent residues. Herein, we developed a fluorescent/colorimetric dual-mode sensor based on bifunctional Mn-doped carbon dots (Mn-CDs). The Mn doping strategy generates abundant catalytically active sites, not only endowing oxidase-like activity, which can catalyze colorless 3,3′,5,5′-tetramethylbenzidine (TMB) to blue products, while simultaneously retaining the intrinsic fluorescence property. Magnetic beads (MBs) conjugated with ACE aptamer (Apt) (MBs@Apt) and Mn-CDs conjugated with DNA1 (Mn-CDs@DNA1) were engineered for hybridization. Upon ACE addition, it will trigger competitive displacement of Mn-CDs@DNA1 from MBs, inducing simultaneous colorimetric and fluorescent signal changes. This displacement mechanism enables dual-mode ACE quantification with high sensitivity (LOD = 15.36 fg/mL for fluorescence mode and 57.54 fg/mL for colorimetric mode) and selectivity. The sensor achieves reliable detection in complex matrices, providing a rapid, high-performance solution for pesticide monitoring.
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ANALYTICA CHIMICA ACTA
·
2025
·
IF 6
Rong Huang,Zhong Dong,Wanyi Zhang,Zhenggang Xue,Dongmei Deng,Wei Wang,Yuanyuan Li,Haibo He,Liqiang Luo
Background Organophosphorus pesticides contamination significantly threatens the ecological environment. Therefore, developing sensitive and efficient point-of-care detection methods is essential. Results In this work, Cu−N 4 single-atom nanozymes on nitrogen-doped carbon (Cu SAs/NC) with dual enzyme-mimicking activities (peroxidase-like and oxidase-like) were prepared for point-of-care detection of parathion using acetylcholinesterase inhibition-based colorimetric sensing mechanism. Cu SAs/NC shows high catalytic activity with high turnover number (K cat ) of ∼24.07 min −1 and K cat /K m of ∼1.35×10 5 M −1 min −1 . Experimental findings in combination with density functional theory simulations demonstrate that Cu centers in Cu SAs/NC play a pivotal role in intermediate binding optimization, which contributes to a decreased reaction energy barrier. Hence, a colorimetric sensing platform based on Cu SAs/NC was constructed for point-of-care detection of parathion, achieving a detection limit of 0.79 ng mL −1 . Significance This study provides a novel strategy for structuring single-atom nanozymes with enhanced enzyme-mimicking activity, showing great promise for advanced environmental protection.
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OPTICS COMMUNICATIONS
·
2023
·
IF 2.4
Tingting Lang,JinHui Zhang,Yanqing Qiu,Zhi Hong,Jianjun Liu
In this paper, a flexible terahertz (THz) Metamaterial (MM) with high sensitivity is proposed for the detection of the pesticide imidacloprid. The MM sensor is composed of a polyimide (PI) substrate and a periodic aluminum (Al) split ring resonator array. The sensing performance of the MM is verified by both simulation and experiment. The simulation results show that the refractive index (RI) sensitivity of the proposed MM sensor is 220.7 GHz/RIU, and the figure of merit (FOM) of this MM is 1.52. Then, the sensing performance of the MM sensor is verified by using imidacloprid solutions with different concentrations. The experimental results show that the detection sensitivity of the MM sensor is 12.3 GHz/(mg/ml), and the limit of detection (LOD) is 0.0112 mg/ml. The THz MM sensor proposed in this paper is flexible, simple to make, cost-effective, highly sensitive and has a very broad application prospect in the concentration detection of pesticides such as imidacloprid.
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AQUATIC TOXICOLOGY
·
2023
·
IF 4.5
Lingyun Fan,Xujia Zhang,Jia Wang,Chen Wang,Shaochen Li,Yuan Hui Zhao,Christopher J. Martyniuk
Neonicotinoids are widely used pesticides that contaminate aquatic environments. Although these chemicals can be photolyzed under sunlight radiation, it is unclear for the relationship between photolysis mechanism and toxicity change in aquatic organisms. This study aims to determine the photo-enhanced toxicity of four neonicotinoids with different main structures (acetamiprid, and thiacloprid for cyano-amidine structure, imidacloprid and imidaclothiz for nitroguanidine). To Achieve the goal, photolysis kinetics, effect of dissolved organic matter (DOM) and reactive oxygen species (ROSs) scavengers on photolysis rates, photoproducts, and photo-enhanced toxicity to Vibrio fischeri were investigated for four neonicotinoids. The results showed direct photolysis plays a key role in the photo-degradation of imidacloprid and imidaclothiz (photolysis rate constants are 7.85 × 10 −3 and 6.48 × 10 −3 min −1 , respectively), while the photosensitization process of acetamiprid and thiacloprid was dominated by ·OH reactions and transformation (photolysis rate constants are 1.16 × 10 −4 and 1.21 × 10 −4 min −1 , respectively). All four neonicotinoid insecticides exerted photo-enhanced toxicity to Vibrio fischeri , indicating photolytic product(s) posed greater toxicity than their parent compounds. The addition of DOM and ROS scavengers influenced photo-chemical transformation rates of parent compounds and their intermediates, leading to diverse effects on photolysis rates and photo-enhanced toxicity for the four insecticides as a result of different photo-chemical transformation processes. Based upon the detection of chemical structures of intermediates and Gaussian calculations, we observed different photo-enhanced toxicity mechanisms for the four neonicotinoid insecticides. Molecular docking was used to analyze the toxicity mechanism of parent compounds and photolytic products. A theoretical model was subsequently employed to describe the variability of toxicity response to each of the four neonicotinoids.
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CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Peng Xu,Xiang Li,Rui Wei,Chunyan Yang,Tianyao Shen,Peng Wang,Guangshan Zhang
The adaptability and stability of catalysts guarantee efficient catalytic performance. Hence, we fabricated FeCo 2 O 4 /diatomite for efficient peroxymonosulfate (PMS) activation. Distinct from stacked FeCo 2 O 4 , FeCo 2 O 4 /diatomite possessed a 1.2-fold larger specific surface area (94.84 m 2 g −1 ), achieving 100% ATZ removal within 10 min at 0.2 g L −1 PMS and 0.1 g L −1 FeCo 2 O 4 /diatomite. The system could adapt to a broad pH range (3–11) and complex water matrices, efficiently removing multiple contaminants. High removal performance (>92%) and mineralization (>57%) were maintained after six cycles with minimal leached Co (0.10 mg L −1 ). The conversion between ≡Fe(III)/≡Fe(II) and ≡Co(III)/≡Co(II) could trigger PMS persistently, producing abundant active species, in which SO 4 •− was dominant. Then, intermediates and degradation pathways were proposed based on DFT calculations and ESI-QTOF-MS/MS data. Toxicity analysis showed that most intermediates were more eco-friendly than ATZ. This study developed FeCo 2 O 4 /diatomite with superior catalytic performance, high adaptability, and stability for eliminating refractory organic pollutants.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2023
·
IF 4.4
Qi Shao,Chunhui Jiang,Xu Chen,Anguan Wang,Linchuan Lu,Liang Chen,Hongfei Lu
In this study, we used purine hydrazone derivatives and coumarin aldehyde to synthesize a novel fluorescent sensor ( EDTP ) by Schiff base reaction, which exhibited significant selective fluorescence quenching of Cu 2+ , and a distinct change from brilliant yellow to red is present along with the solution color. The detection limit of EDTP for Cu 2+ was 109.52 nM. Job's plot experiment, density flooding theory (DFT) and 1 H NMR titration experiments revealed the possible binding mechanism of EDTP to Cu 2+ , the probe EDTP could achieve highly detection of Cu 2+ through forming a 1:1 complex. Additionally, this new fluorescent sensor EDTP -Cu 2+ can be further applied in the rapid and selective detection of pesticide residues in solutions. When the EDTP -Cu 2+ system was subsequently exposed to organophosphorus pesticides (glyphosate and glufosinate-ammonium), it was observed that the fluorescence was recovered and accompanied by a red to yellow color change. This may be attributed to the strong chelation of glyphosate and glufosinate-ammonium with Cu 2+ , leading to the dissociation of the EDTP -Cu 2+ system and thus triggering the fluorescence recovery effect. The detection limits of the EDTP -Cu 2+ system is 2.48 nM for glyphosate and 17.23 nM for glufosinate-ammonium, respectively. Finally, the developed sensor system has been successfully utilized image glyphosate and glufosinate-ammonium fluorescence in living cells. Purine fluorescence probes are a potential fluorescent probe for the detection of metal ions and pesticides due to their good characteristics. This study opens up a new way for the detection of fluorescent probes in pesticides.
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NEW JOURNAL OF CHEMISTRY
·
2023
·Vol. 47
·期 16
·7722-7732
·
IF 3.3
Liran Tian,Xiangwei Song,Tianjiao Liu,Anfeng Li,Yang Ning,Xiuyi Hua,Deming Dong,Dapeng Liang
Based on the specific identification ability of aptamers towards a target, a combined UV-Visible with fluorescence detection method for acetamiprid was designed. In the absence of acetamiprid, AuNPs were uniformly distributed and had a good quenching ability for Rhodamine B's fluorescence at a higher NaCl concentration. In the presence of acetamiprid, a few AuNPs lost their protective effect and aggregated, meanwhile, the absorption peak of the UV-vis spectrum gradually redshifted from 520 nm to 680 nm. Additionally, the quenching effect of AuNPs on Rhodamine B was diminished when aggregation took place. Thus the presence of acetamiprid could be clearly determined using a UV-vis or fluorescence method. The combination of the two routes had a wider detection range and a detection limit as low as 0.0559 μM. This method was successfully used to determine acetamiprid in spiked lake water samples and would be a potential simple method for the determination of acetamiprid residues in natural water bodies.
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MICROCHEMICAL JOURNAL
·
2023
·
IF 4.8
Xiaoning Liao,Xiaoyao Luo,Yiyang Li,Ying Zhou,Qi Liang,Kehuai Feng,María Belén Camarada,Jianhua Xiong
Carbendazim (CBZ) was widest used in agriculture for its high efficiency in controlling of fungal diseases. However, CBZ can pose serious contamination to agricultural products and water resource for its long half-lives and high toxicity. Therefore, precise detection of CBZ residues is very important for human health and environmental safety concerns. Nevertheless, the inherent electrode fouling effect caused by CBZ products hinders the precise and practical determination of CBZ. Herein, a novel highly antifouling heterostructure based on carboxylated multiwalled carbon nanotubes (MWCNT-COOH) functionalized black phosphorus (BP) have been successfully developed via a facile sonication assisted self-assembly method. The electrochemical interface of BP/MWCNT-COOH modified glassy carbon electrode shows excellent catalytic activity to CBZ oxidation and good electrode antifouling effect, ensuring repeatable and precise detection of CBZ. In addition, the sensor shows a wide linearity from 9.0 nM to 1000 nM with a detection limit of 4.0 nM which superior to most of previous work. Moreover, the BP-based non-enzymatic sensor shows good selectivity and satisfactory recoveries for real sample analysis, confirming its highly practical application. The antifouling mechanism to CBZ for the sensor and the interaction mechanism between MWCNTs-COOH and BP were also illustrated by theory calculations.
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RSC Advances
·
2023
·Vol. 13
·期 13
·8765-8778
·
IF 3.9
Niannian Cao,Jiawen Ji,Changsheng Li,Meng Yuan,Xuanjun Guo,Xingxing Zong,Liqin Li,Yongqiang Ma,Chen Wang,Sen Pang
Tricyclazole, propiconazole, imidacloprid, and thiamethoxam are commonly used pesticides in paddy fields. It is necessary and practical to remove pesticides from the water environment because the low utilization rate of pesticides will produce residues in the water environment. It is known that there are few studies on the preparation of biochar adsorption pesticides by the walnut shell and few studies on the removal of tricyclazole and propiconazole. Based on this, this paper used the walnut shell as raw material and boric acid as an activator to prepare biochar by the one-step method. The boric acid modified walnut shell biochar (WAB4) with a specific surface area of 640.6 m2 g−1, exhibited the high adsorption capacity of all four pesticides (>70%) at pH 3–9. The adsorption capacities of tricyclazole, propiconazole, imidacloprid, and thiamethoxam were 171.67, 112.27, 156.40, and 137.46 mg g−1, respectively. The adsorption kinetics fitted the pseudo-second-order kinetic model and the adsorption isotherm curves conformed to the Freundlich isotherm model. The adsorption of pesticides by WAB4 was associated with hydrogen bonding, pore filling, hydrophobic effects, and π–π interactions. More significantly, WAB4 has excellent adsorption capacity compared to other adsorbents for real water samples. Finally, walnut shell biochar has no significant acute toxicity to Daphnia magna. This work shows that walnut shell-based biochar has a good effect on the removal of pesticides at a wide range of pH and is economical and safe, providing a new idea for the removal of pesticides in water.
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PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
·
2023
·
IF 4.7
Zhenyu Li,Mengling Chen,Wenjie Bai,Shuxia Zhang,Liwei Meng,Wei Dou,Jinjun Wang,Guorui Yuan
Carboxylesterases (CarEs) are a multifunctional superfamily of enzymes and play an important role in detoxification of various insecticides in insects. The oriental fruit fly, Bactrocera dorsalis , is one of the most destructive agricultural pests and has developed different degrees of resistance to organophosphates in field. However, the involvement of BdCarEs in tolerance or resistance to other alternative insecticides are still unclear. In the present study, 33 BdCarEs genes were identified based on the genome database of B. dorsalis . Phylogenetic analysis demonstrated that they were classified into nine clades, with abundance of α -esterases. Meanwhile, the sequence characterization and the chromosome distribution were also analyzed. The spatiotemporal expression analysis of BdCarEs genes suggested that the diversity of potential function in different physiological processes . With the exception of BdCarE21 , all BdCarEs genes responded to at least one insecticide exposure, and BdCarE20 was found to be up-regulated after exposure to all five tested insecticides individually. Eight BdCarEs genes were overexpressed in MR strain when compared to that in SS strain. Subsequently, knockdown the expression of representative BdCarEs genes significantly increased the susceptibility of the oriental fruit fly to corresponding insecticides, which indicated that the tested BdCarEs genes contributed to one or multiple insecticide detoxification. These findings provide valuable insights into the potential role in respond to tolerance or resistance to insecticides with different mode of action, and will facilitate development of efficiency management strategy for B. dorsalis .
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Biosensors-Basel
·
2023
·Vol. 13
·期 5
·504
·
IF 5.4
Weifu Geng,Yan Feng,Yu Chen,Xin Zhang,Haoyi Zhang,Fanfan Yang,Xiuzhong Wang
As a type of aggregation-induced emission (AIE) fluorescent probe, tetraphenylvinyl (TPE) or its derivatives are widely used in chemical imaging, biosensing and medical diagnosis. However, most studies have focused on molecular modification and functionalization of AIE to enhance the fluorescence emission intensity. There are few studies on the interaction between aggregation-induced emission luminogens (AIEgens) and nucleic acids, which was investigated in this paper. Experimental results showed the formation of a complex of AIE/DNA, leading to the quenching of the fluorescence of AIE molecules. Fluorescent test experiments with different temperatures proved that the quenching type was static quenching. The quenching constants, binding constants and thermodynamic parameters demonstrated that electrostatic and hydrophobic interactions promoted the binding process. Then, a label-free “on-off-on” fluorescent aptamer sensor for the detection of ampicillin (AMP) was constructed based on the interaction between the AIE probe and the aptamer of AMP. Linear range of the sensor is 0.2–10 nM with a limit of detection 0.06 nM. This fluorescent sensor was applied to detect AMP in real samples.Keywords:aggregation-induced emission;DNA;label-free;biosensor;antibiotic
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ANALYTICA CHIMICA ACTA
·
2023
·
IF 6.2
Yue Tang,Xiangqiang Zhan,Jia Zheng,Zhengmin Xie,Shuangju Zhu,Yuangen Wu
The long-term and excessive use of organophosphorus pesticides (OPs) leads to hazardous residues in the environment, which threatens human health to a considerable extent. Colorimetric methods can quickly and readily identify pesticide residue , but they still have various challenges in accuracy and stability. Herein, a smartphone-assisted and non-enzymatic colorimetric biosensor was constructed for rapid monitoring of multiple OPs based on the enhanced effect of aptamer on the catalytic ability of octahedral Ag 2 O. It was demonstrated that the aptamer sequence could enhance the affinity of colloidal Ag 2 O to chromogenic substrates, and accelerate the generation of oxygen radicals such as superoxide radical (·O 2 − ) and singlet oxygen ( 1 O 2 ) from dissolved oxygen, thereby significantly increasing the oxidase activity of octahedral Ag 2 O. The color change of the solution can be easily converted to the corresponding RGB values by a smartphone for quantitative and rapid detection of multiple OPs. Hence, the smartphone-based and visual biosensor of multiple OPs was acquired with limit of detection of 10 μg L −1 , 28 μg L −1 and 40 μg L −1 for isocarbophos , profenofos and omethoate , respectively. The colorimetric biosensor also exhibited good recoveries in several environmental and biological samples, showing that it may have broad application prospects for detecting OPs residues.
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