TALANTA
·
2025
·
IF 6.1
Xiwang Hou,Tianhao Chen,Chunyan Wang,Fanyu Liu,Minggang Zhao,Ye Ma
The concentration range of uric acid (UA) varies significantly across different biological fluids, and therefore, highly sensitive and wide-range detection of UA is of great importance for the early diagnosis of UA-related diseases. Surface-enhanced Raman spectroscopy (SERS) offers high sensitivity and molecular fingerprint specificity; however, challenges remain regarding its signal uniformity and detection range. In this work, a uniform and stable two-dimensional metasurface is constructed via liquid–liquid interface (LLI) self-assembly of silver nanoparticles (NPs) functionalized with bis (p-sulfonatophenyl) phenylphosphine di-potassium salt (BSPP). UA is catalytically oxidized by uricase, which in turn oxidizes the BSPP ligands on the NP surface, inducing microstructural changes in the metasurface, which led to a decrease in the BSPP signal in the SERS mode at low UA concentrations and a reduction in reflectance in the reflectance mode at high UA concentrations. Using this dual-mode strategy, a detection limit (LOD) of 3.22 ± 0.10 nM for UA and a dynamic range of 0.100–1500 μM are achieved. The strategy enables rapid NPs assembly and complementary linear ranges, offering a versatile approach with potential for extension to diverse analytes and portable point-of-care applications, highlighting its potential significance for the early diagnosis of UA–related diseases.
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Tungsten
·
2025
·
IF 11.2
Wang Xue,Zhang Li,Han Yu,Li Feng-Bo,Li Shao-Bin
Accurate non-invasive glucose monitoring is crucial for health diagnostics. However, the development of high-performance non-enzymatic electrochemical sensors for this application remains a significant challenge. To address this issue, a novel material, FeOOH encapsulated within zeolitic imidazolate framework-67 (ZIF-67)-derived copper-cobalt-layered double hydroxide (FeOOH@CuCo-LDH), was developed through a vapor-assisted deprotonation process for FeOOH encapsulation, followed by a hydrothermal reaction to synthesize the hollow composite. The synergistic interactions between the multi-metallic composition and the hollow structure significantly enhance glucose oxidation-reduction reactions. This enables the sensor to achieve a wide linear detection range (0.5–722 μmol·L −1 and 722–4222 μmol·L −1 ), high sensitivity (4.05 and 1.43 μA·L·μmol −1 ·cm −2 ), and a low limit of detection (0.83 μmol·L −1 ). The sensor demonstrated excellent performance in practical applications, accurately detecting glucose in saliva under physiological conditions. This study highlights the potential of FeOOH@CuCo-LDH as an excellent electrode material for non-enzymatic electrochemical glucose sensing, offering promising applications in diabetes prevention and diagnosis. Graphical abstract
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Journal of Analysis and Testing
·
2025
·
IF 7
Yan Jieyu,Wang Zhen,Li Jingwen,Li Yifei,Wu Zhengjiang,Zhang Yirui,Han Kun
Accurate and sensitive detection of protein biomarkers is critical for early disease diagnosis and therapeutic monitoring. This study introduces a novel isothermal proximity CRISPR-Cas12a assay for the detection of C-reactive protein (CRP), a key biomarker for inflammation and disease progression. By employing a DNA-antibody bioconjugate strategy, this method converts protein recognition into DNA signals, enabling multiple signal amplification cascades. The proximity hybridization of antibody probes triggers the Cas12a trans-cleavage activity, releasing detectable signals in fluorescence and commercial test strips. Dual-mode detection was realized, with detection limits of 0.57 ng/mL for fluorescence and 2.63 ng/mL for test strips. Linearity detection ranges were found to be 0.1–100 µg/mL. Furthermore, it exhibited high specificity against interfering substances in blood. Clinical serum samples were analyzed, demonstrating the assay’s robustness and practicality under physiological conditions. This approach enhances the detection of CRP and provides a versatile framework for the quantitative analysis of various protein biomarkers, offering an alternative solution for clinical protein diagnosis for point-of-care tests.
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APPLIED CATALYSIS A-GENERAL
·
2025
·
IF 4.8
Xiaoling Chen,Yujuan Lu,Hui Li,Hongwei Mi,Guoqiang Zhang
Non-radiative recombination is the key bottleneck to overcome the charge separation problem. Here, we use poly(heptazine imide) (PHI) as a model photocatalyst to investigate the effect of internal electric field (IEF) on non-radiative recombination. Introducing electron-deficient boron atoms into the PHI structure leads to an uneven distribution of in-plane charges, spontaneously polarizing the formation of an IEF. This enhanced IEF can exert a force on the carrier in the opposite direction of the Coulomb force, thus effectively weakening the carrier trapping by the charged defect, thereby suppressing the non-radiative recombination. This is the first systematic research of suppressing non-radiative recombination by IEF in photocatalysis, which provides guiding strategies for addressing the bottleneck of charge separation in photocatalysis.
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MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Qi Liang,Tao Liao,Liqin Zhu,Changxiang Liu,Qian Liu,Jianhua Xiong,Ruiping Deng,Xiaoning Liao
A novel nanocomposite consisting of core (Cu)-shell (Ag) nanoparticles encapsulated in carbon nanotubes (CTs) grown on a MOF-derived carbon framework was synthesized by in-situ pyrolyzing method. After further modification with multi-walled carbon nanotubes (MWCNTs), a hierarchical porous carbon network confined core (Cu)-shell (Ag) bimetal (Cu@Ag@CTs/MWCNTs) with excellent catalytic properties to isoproturon (ISO) and norfloxacin (NOR) was obtained. The electrochemical sensor based on the Cu@Ag@CTs/MWCNTs can simultaneously detect the ISO and NOR with excellent sensitivity, good selectivity and perfect stability as well as a separation of peak potential of 270 mV. The calibration curves for ISO and NOR achieved by the proposed sensor range from 80 nM to 18 μM and 7.0 nM to 1.7 μM with detection limits of 26 nM and 2.0 nM, respectively. Moreover, the sensor shows good recoveries in simultaneous detection of ISO and NOR in real sample analysis, highlighting its high feasibility in practical application.
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LUMINESCENCE
·
2025
·Vol. 40
·期 11
·e70328
·
IF 3
Tingting Lei,Yating Xu,Siyi Tan,Jiafu Xiao,Shaojing Zhao,Minhuan Lan
An ability to effectively detect glyphosate residues in food and the environment on-site remains a challenge. Herein, we developed a ratiometric fluorescent sensing platform based on blue fluorescent carbon dots (B-CDs) and red carbon dots (R-CDs) for rapid, visual, and quantitative detection of glyphosate. Although B-CDs, which were functionalized with abundant amino and hydroxyl groups, caused glyphosate-mediated aggregation-caused quenching (ACQ) via hydrogen bonding effect, R-CDs acted as a stable internal reference. The system could detect glyphosate in one step within 20 s and had a low detection limit of 2.87 μM. During the detection process, the fluorescent color changes from blue to red. On-site detection can be achieved by using the RGB analysis integrated in the smartphone. The sensor had high selectivity to glyphosate, despite the presence of metal ions, biomolecules, and various pesticides. It was successfully applied to detect actual water samples with recovery rates of 81.8%–96.6% (RSD ≤ 11.1%). With its rapid response, smartphone compatibility, and robustness in detecting complex matrices, the proposed sensor has promising potential for the monitoring of glyphosate in agricultural and environmental samples.
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CHEMISTRY OF MATERIALS
·
2025
·
IF 7
Luyong Zhang,Zhencheng Wu,Jingdong Yan,Shibin Wang,Zilong Chen,Zhihua Yang,Fangfang Zhang,Shilie Pan
Sulfates have remained promising candidates for deep-ultraviolet (DUV) optical crystals owing to the inherently wide bandgaps induced by the [SO4] tetrahedral groups. However, the structural rigidity of [SO4] tetrahedra imposes severe restrictions on the polarization anisotropy, fundamentally preventing sulfates from achieving sufficient birefringence required for regulating light polarization. Herein, by incorporating f0 rare earth metal cation Y3+ into alkali metal sulfates, we synthesized six compounds, AY(SO4)2 and A3Y(SO4)3 (A = K, Rb, Cs). They exhibit dramatically enhanced birefringence between 0.013–0.056 at 546 nm, with up to 25 times that of their parent alkali metal sulfates, which originate from the highly aberrant Y–O polyhedra and the dimensionality reduction of the Y–O–S network regulated by A-site cations. This study provides valuable insights into the further exploration of sulfate-based optical materials.
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ACS Nano
·
2025
·
IF 16
Zhitong Xiao,Yongfeng Jia,Lujun Zhu,Chenxi Zheng,Wei Hao,Pengfei Zhang,Jiashen Meng,Mengxue He,Lei Ji,Jian Wang,Mohammadhosein Safari,Yakun Liu,Wei Wen,Quanquan Pang
Molten salt aluminum batteries (MSABs) hold significant promise for grid-scale energy storage due to the low cost and high capacity of the aluminum anode. However, an aluminum dendrite stemming from nonuniform electrodeposition leads to safety and stability issues. Here, we describe a membrane electrode with predeposited aluminum metal featuring surface-mediated nucleation and growth behavior for operation in alkali chloroaluminate melt electrolytes. The introduction of TiN, as aluminophilic sites, facilitates the initial growth of aluminum on TiN by forming Al–N bonding, thereby enabling uniform aluminum nucleation and mediated growth along the TiN/C fiber, resulting in reversible and dendrite-free aluminum plating/stripping. The TiN/C@Al electrode enables symmetric cells to maintain stable cycling for over 850 h (10.0 mA cm–2; 5.0 mA h cm–2) and shows high rate performance at up to 30.0 mA cm–2. The Al-graphite cell using a TiN/C@Al anode demonstrates long-term stability over 7000 cycles at 2.0 A g–1 and enhanced rate capability with 72.2 mA h g–1 even at 5.0 A g–1. To validate practical scalability, we designed an Ah-level TiN/C@Al-based molten salt Al-graphite pouch cell. This approach offers a scalable pathway for overcoming the limitations of state-of-the-art anodes in MSABs, enabling high-performance and cost-effective energy storage solutions.
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Advanced Science
·
2025
·Vol. 12
·期 34
·e04489
·
IF 14.1
Junyu Lu,Lei Xu,Cheng Xie,Chang Zhang,Zhaohui Han,Yiyao Ren,Renchao Che
The advancement of wireless communication technologies necessitates materials that absorb electromagnetic waves and shield against electromagnetic interference. The research is propelled by the necessity to develop materials that possess both properties. Here, an electromagnetic wave-absorbing material that synergistically regulates dielectric and magnetic properties is developed. The material features a nanowire fabric/multilayer composite structure of expanded graphite@α-MnO 2 (EG@MO). The manganese oxide nanowires are prepared in situ on the surface of multilayer expanded graphite via microwave-assisted hydrothermal synthesis. A rapid microwave activation process is subsequently performed to convert manganese oxide-hydroxide, elevating its oxidation state, and transforming it from a non-magnetic form to the magnetic α-MnO 2 . The EG@MO exhibits exceptional electromagnetic wave absorption capabilities, achieving a reflection loss value of −75.56 dB, with a low filler ratio of 7 wt.% and an ultrathin thickness of 1.48 mm. This high-performance electromagnetic absorption material, fabricated by integrating magnetic manganese dioxide nanowires with multilayer expanded graphite, shows excellent widespread applications.
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FULLERENES NANOTUBES AND CARBON NANOSTRUCTURES
·
2025
·
IF 1.8
Zekun Li,Bo Meng
Conventional methods of preparing carbon nano in most cases prepare worm-like carbon nanomaterials in a single dispersed arrangement, agglomerated into a spherical worm-like carbon nano is more special and uncommon. Tetradecyl trimethyl ammonium bromide (TTAB) and potassium chloride were used as raw materials, and sphericity of worm-like carbon nano could be prepared by in situ carbonization method. This particular morphology is called worm-like carbon nanospheres. The yield of worm-like carbon nanospheres was calculated to be about 5‰ using tetradecyl trimethyl ammonium bromide as the carbon source. A series of characterization means such as SEM, FT-IR, Raman, XRD and XPS were used for characterization. The characterization results show that the size of worm-like carbon nanospheres is between 300 and 600 nm, relatively dispersed, and the aggregation phenomenon is not obvious. The structure of worm-like carbon nanospheres has some defects with graphitization degree ID/IG = 0.8. About the formation mechanism of worm-like carbon nanospheres is explained accordingly in the existing cases.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2025
·
IF 4.6
Tao Tian,Yifei Mao,Sheng Gong,Liang Zou,Yizong Huang,Yanshan Cui,Jinchao Wei,Peng Li
Although copper is essential for various functions in the human body, excessive intake can damage the nervous and immune systems. In this study, a new fluorescent covalent organic framework probe (DP-TFPB COF) was first reported. Relying on the rational design, the synthesized DP-TFPB COF demonstrates a distinctive fluorescence enhancement effect upon different solvent induction, achieving a quantum yield of up to 20.5 %. Then, a covalent organic framework-based ratiometric fluorescent system was developed, incorporating blue-emitting carbon dots to leverage the fluorescence energy transfer effect. Blue-emitting carbon dots served as the reference signal, while the DP-TFPB COF acted as the response unit, enabling successful quantitative detection of Cu 2+ . The mechanism study demonstrated that fluorescence quenching occurs through an electron transfer process, wherein the covalent organic framework serves as the electron donor and Cu 2+ functions as the electron acceptor. The developed method demonstrated excellent linearity for Cu 2+ within the concentration range of 0.5 to 200 μM, accompanied by a detection limit of 0.38 μM. The robust recognition capabilities exhibited significant effectiveness in the Cu 2+ analysis within herbal plants. The results correspond closely with those obtained using inductively coupled plasma mass spectrometry, thereby emphasizing its potential applicability in real samples with complex matrix.
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Nature Communications
·
2026
·
IF 18.1
Wang Shengnan,Gao Yao,Wang Shixun,Ai Mingzhong,Guo Yihui,Liu Xingjun,Wang Yiqiao,Wei Zhiquan,Zhu Jiaxiong,Nian Qingshun,Zhang Cuili,Wang Lang,Lu Shengbo,Liu Tracy Chenmin,Li Quan,Zhi Chunyi
Zinc-based flow batteries are gaining attention as safe, cost-effective, and sustainable energy storage solutions amid global energy transition challenges. However, their practical application is hindered by poor reversibility and dendrite formation of Zn negative electrode, particularly under high state-of-charge conditions. Despite extensive research on Zn side, the relationship between localized temperature distribution and dendrites remains underexplored, primarily due to limited microscopic observation techniques. Here, we present a non-invasive optically detected magnetic resonance with nanodiamond quantum sensors to monitor temperature variations during Zn deposition, achieving a sub-micron spatial resolution ( ~ 300 nm) and a temperature sensitivity of ~2 K/Hz 0.5 . Our findings suggest that spatial temperature non-uniformity may play a critical role in accelerating dendrite growth and potentially leading to more severe short circuits. Simulations revealed that higher substrate thermal conductivity improves Zn deposition uniformity. Herein, we introduced a flowable gallium-indium liquid metal electrode, which disperses localized heat and lowers interfacial temperature gradients, thereby suppressing hotspot-driven dendrite growth and enabling in situ formation of a liquid Zn alloy. The zinc-bromine flow battery with the liquid metal electrode demonstrated enhanced cycling stability over 2400 hours at a high state-of-charge of 90%, achieving a cumulative discharge capacity of 46.2 Ah cm −2 at 40 mA cm −2 .
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