JOURNAL OF LUMINESCENCE
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2026
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IF 3.8
Chenchen Nie,Shanshu Yan,Gaoyuan Xing,Kaixin Ji,Xing Yang,Jianfeng Tang,Jiucun Chen,Yanan Zhao,Jie Hu,Jing Liu
Precise regulation of endogenous reactive oxygen species (ROS) is critical for maintaining physiological homeostasis, while dysregulated ROS levels are implicated in diverse pathologies. In vivo monitoring of this key signaling molecule represents an urgent priority, yet poses significant challenges due to the limitations of conventional ROS probes reliant on ultraviolet-visible excitation for high-fidelity biological imaging. To address this constraint, we engineered a luminescent nanoprobe by conjugating IR783 with upconversion nanoparticles (UCNPs), enabling H 2 O 2 detection via upconversion luminescence. The detection mechanism involves ROS-triggered cleavage of IR783, inducing nanostructure disassembly and subsequent restoration of upconversion luminescence. This design yields a concentration-dependent luminescence turn-on response, where upconversion luminescence intensity escalates proportionally with H 2 O 2 levels. The UCNPs-IR783 nanoprobe exhibits minimal cross-reactivity with biomolecules and low cytotoxicity, enabling effective visualization of both intrinsic and extrinsic reactive oxygen species within Hepa1-6 and RAW264.7 cellular models. Furthermore, investigations in murine subjects validate its applicability for ROS detection specifically within the tumor microenvironment.
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Journal of Marine Science and Engineering
·
2026
·Vol. 14
·期 14
·1311
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IF 3.2
Daping Zhou,Shuye Xue,Ye Qiu,Xiangming Zeng,Haijun Wei,Shen Wu
The instability of marine low-sulfur fuel oil caused by asphaltene precipitation poses significant operational challenges in the shipping industry. This study systematically investigates the dispersing effects of biodiesel derived from three different feedstocks—palm oil, waste cooking oil (WCO), and microalgae oil—and their individual fatty acid methyl ester components on asphaltenes extracted from VLSFO. Biodiesel was selected as a dispersant due to its renewable nature, polar ester functional groups, and variable unsaturation levels, which enable favorable interactions with asphaltene molecules through hydrogen bonding and π-π stacking. Using UV–Visible spectrophotometry, the dispersion performance was quantitatively evaluated under various conditions including dispersant concentration, temperature, storage time, and molecular structural characteristics. The results demonstrate that microalgae oil biodiesel exhibits the most superior asphaltene dispersion capability among the three biodiesels, with a dispersion improvement index of 35% at 12 g/L, compared to 28% and 22% for waste cooking and palm oil biodiesels. Optimal performance is achieved at 80 °C, where the asphaltene concentration increases by 68% relative to the control, and remains stable within the first 10 days of storage but deteriorates significantly after 30 days due to oxidative degradation. Among individual FAME components, the dispersion effectiveness increases with alkyl chain length from C10 to C20, with the latter reaching a 30% improvement index. Functional group polarity plays a critical role, with carboxylic acid exhibiting a 45% improvement at 14 g/L, substantially outperforming alcohol at 32% and ester at 28%. The degree of unsaturation further enhances dispersion, as the improvement index rises progressively from 20% for saturated methyl stearate to 42% for tri-unsaturated methyl linolenate, representing a 2.1-fold increase. Dynamic light scattering (DLS) measurements confirm that biodiesel addition reduces asphaltene particle size from the micrometer range of 2 to 5 μm down to submicron levels of 200 to 500 nm, while microscopic observations reveal inhibited aggregation. These findings provide theoretical foundations for biodiesel application in marine fuel systems.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2026
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IF 9.6
Kefei Cheng,Xianghan Ye,Yating Zhu,Kaixuan Meng,Yinyin Qian
The synthesis of efficient heterojunction nanocomposite with optimized carrier dynamics remains a key challenge in material design. Herein, we report the electrostatic assembly of a CsCu 2 Br 3 /Ag 2 Se heterojunction nanocomposite, in which oppositely charged nanocrystals spontaneously integrate through electrostatic interactions, forming intimate interfacial contact and thereby enhancing carrier transfer. The resulting type-II band alignment induces carrier redistribution at the interface and generates an internal electric field that enables carrier separation without the need for external bias. Density functional theory calculations and ultraviolet photoelectron spectroscopy results confirm the type-II alignment, providing insights into interfacial carrier dynamics. The device exhibits a broadband photoresponse from 405 to 1550 nm, with high photocurrent, reduced noise, and rapid response times (37.1 and 28.4 μs for rise and decay, respectively). Furthermore, the device exhibits stable performance, high-frequency modulation (∼7 kHz), and spatially resolved photocurrent mapping, indicating its potential for near-infrared imaging. Overall, the results demonstrate that electrostatic assembly is an effective strategy for engineering type-II heterojunction interfaces for self-powered broadband photodetection Download: Download high-res image (215KB) Download: Download full-size image
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FOOD RESEARCH INTERNATIONAL
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2026
·
IF 8.8
Daoming Li,Gaimiao Li,Jiandong Wang,Yuhao Li,Minguang Gao,Zhenbao Zhu,Duan Zhou
TDESs simultaneously enhance CALB activity, stability, and DAG selectivity. • ChCl:Gly:U (1,1:1) shows optimal catalytic performance. • Hydrogen-bond networks regulate CALB conformation and catalytic function. • DESs enable high-yield DAG synthesis with reduced by-product formation. Solvent engineering plays a crucial role in improving lipase performance in non-aqueous biocatalytic systems, particularly for the efficient and selective production of functional lipids. In this study, choline chloride-glycerol-urea ternary deep eutectic solvents (TDESs) were constructed to regulate the catalytic behavior of Candida antarctica lipase B (CALB), and the relationships between solvent physicochemical properties, enzyme conformation, and catalytic performance were systematically evaluated through enzymatic assays, fluorescence spectroscopy, and molecular dynamics simulations. Compared with binary DES and solvent free systems, TDESs exhibited lower water activity, tunable viscosity, and strengthened hydrogen-bonding networks, providing a more stable microenvironment for CALB. The optimal ChCl:Gly:U (1:1:1) system enhanced catalytic activity by 2.8-fold and retained over 80% residual activity after thermal treatment. Simulation results indicated reduced RMSD, RMSF, and SASA values, suggesting improved structural compactness. Subtle changes in interaction behavior within the catalytic triad (Ser105-His224-Asp187) were also observed, indicating localized modulation of active-site dynamics that may contribute to enhanced flexibility. In esterification, ChCl:Gly:U increased DAG content to 61% and reduced MAG content to <15% (vs. 45% DAG and 32% MAG in the solvent free system). In addition, the selectivity of DAG formation in TDES systems increased significantly from 57.66% to 73.61%. These findings demonstrate that rationally designed TDESs effectively enhance CALB activity, stability, and DAG selectivity, providing a feasible and sustainable strategy for enzymatic lipid modification. Download: Download high-res image (228KB) Download: Download full-size image
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JOURNAL OF ALLOYS AND COMPOUNDS
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2026
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IF 6.7
Ziyang Niu,Zijun Huang,Peng Wang,Xiuquan Gu,Yulong Zhao
All-inorganic perovskite CsPbBr 3 nanocrystals (NCs) are promising for wide-color-gamut displays due to their high photoluminescence quantum yield (PLQY) and narrow emission bandwidth, yet their ionic nature renders them susceptible to degradation by moisture, heat, and mechanical stress, while surface defects induce non-radiative recombination. Herein, we propose a synergistic protection strategy combining ZnO inorganic modification with EPDM flexible polymer encapsulation. A ZnO heterojunction is constructed in situ on CsPbBr 3 NCs via a solution method, after which the modified NCs are dispersed in an EPDM matrix to fabricate flexible composite films. Structural and optical characterizations confirm that ZnO modification effectively suppresses non-radiative recombination, prolonging the average photoluminescence (PL) lifetime to 14.54 ns. XPS and DFT calculations reveal strong interfacial chemical interactions between CsPbBr 3 and ZnO, with an adsorption energy of −1.923 eV, suggesting effective surface-defect passivation. Stability tests demonstrate that after 6 days of water immersion, heating at 90 °C for 60 min, 200% mechanical stretching, and 100 h of UV irradiation, the composite retains 65%, 60%, and 80% of its initial PL intensity, respectively, showing substantially improved multidimensional stability. A white light-emitting diode fabricated using the film exhibits CIE chromaticity coordinates of (0.34, 0.32) and color gamut coverages of 121.2% NTSC and 98.2% Rec. 2020. This strategy simultaneously addresses defect passivation and environmental instability in perovskites, offering a feasible route towards commercial perovskite-based optoelectronic devices.
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ULTRASONICS SONOCHEMISTRY
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2026
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IF 10.2
Shengxin Zhu,Jianwei Liao,Longshi Rao,Yuying Wang,Xiang Huo,Qinghao Zhong,Haoyu Chen,Guisheng Zhong,Xiaodong Niu
Halide perovskite quantum dots (HPQDs) are transformative candidates for next-generation optoelectronic devices, owing to their exceptional optoelectronic properties including widely tunable bandgaps, ultrahigh color purity, and solution processability. However, scalable, deterministic synthesis of high-quality HPQDs with simultaneous ultra-narrow emission linewidth and high photoluminescence quantum yield (PLQY) remains a longstanding challenge, fundamentally limited by the mass transfer bottleneck and poor mixing efficiency of conventional laminar microreactors. Here, we report a biomimetic vein-inspired ultrasonic microreactor integrated with sharp-edged microstructure arrays to address this core challenge. Through systematic multiphysics simulations, we quantitatively decode the acoustic-hydrodynamic coupling mechanism in the microreactor, and establish a quantitative structure-performance relationship between microstructure geometry and sonochemical reaction performance. We identify an optimized cylindrical microstructure configuration that synergistically amplifies acoustic streaming and cavitation yield to break laminar boundary layer confinement. Experimental validation confirms the optimized microreactor enables continuous synthesis of high-quality HPQDs with an ultra-narrow full width at half maximum of 23.28 nm and PLQY up to 78.6%, markedly outperforming conventional microfluidic methods. We further elucidate that cavitation-enhanced micromixing enables dynamic supersaturation tuning, driving LaMer-type size-focusing and homogeneous nucleation for exceptional HPQDs monodispersity. This work provides a generalizable, scalable microfluidic strategy for precision synthesis of high-performance optoelectronic nanomaterials, bridging the critical gap between lab-scale research and industrial translation.
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OPTICS AND LASER TECHNOLOGY
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2026
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IF 5.2
Wei Gao,Jiaxi Li,Junlin Qi,Qingyan Han,Chengyun Zhang,Xuewen Yan,Jun Dong
Balancing red-emission intensity and the red-to-green (R/G) emission ratio remains an important challenge in Er 3+ -based upconversion nanoparticles. Herein, a multilayer core–shell architecture was developed to achieve differential regulation of red-emission intensity and the red-to-green (R/G) emission ratio in Er 3+ -based upconversion nanoparticles. After screening NaYbF 4 : x %Er 3+ @NaYF 4 core–shell nanoparticles, the sample containing 2% Er 3+ exhibited a favorable balance between overall emission intensity and the R/G ratio and was therefore selected as the precursor for constructing NaYbF 4 :2%Er 3+ @NaYF 4 @NaErF 4 :y%M 3+ @NaYF 4 (M = Yb or Tm) multilayer nanoparticles. In this architecture, the Yb-rich core, intermediate NaYF 4 layer, compositionally tunable Er-rich shell, and outer NaYF 4 shell were designed to provide spatially differentiated excitation harvesting, interfacial modulation, spectral regulation, and surface passivation, respectively. Under identical 980 nm excitation and collection conditions, incorporation of 15%Yb 3+ into the Er-rich shell increased the integrated red-emission intensity to 2.40 times that of the undoped multilayer counterpart, whereas incorporation of 0.5%Tm 3+ produced the highest R/G ratio of 17.1 while retaining comparatively strong emission. Power-dependent and time-resolved luminescence measurements, together with the proposed energy-transfer model, indicate that Yb 3+ incorporation is predominantly associated with enhanced local excitation sensitization and energy utilization within the Er-rich region, whereas trace Tm 3+ incorporation is more closely associated with excited-state population redistribution toward the red-emitting pathway. These results demonstrate that red-emission intensity and the R/G ratio can be differentially regulated within the same multilayer platform through Yb 3+ or Tm 3+ incorporation into the Er-rich shell. This work provides a spatially organized and compositionally tunable strategy for tailoring red upconversion emission in Er 3+ -based multilayer nanoparticles.
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ACS Omega
·
2026
·
IF 5.2
Guoshi Lin,Shichang Rao,Xiaocheng Li,Zhipeng Liang,Aishun Guo,Ruisheng Lin,Zongqing Zheng,Weiping Cai
Early diagnosis of glioma, which is the most common and highly malignant primary tumor of the central nervous system, is highly important for improving patient survival rates. MicroRNAs (miRNAs), such as miR-21 and miR-155, are aberrantly expressed in gliomas and serve as potential early diagnostic biomarkers. In this study, an “AND gate” logic fluorescence sensing platform based on upconversion nanoparticle (UCNP) and mesoporous silica (mSiO2) was used for the highly sensitive and specific measurement of the dual targets miR-21 and miR-155. Under optimized conditions, the limits of detection of the method for miR-21 and miR-155 were 0.181 nM and 0.185 nM, respectively, with linear ranges of 0.5∼10 nM. The platform can trigger significant fluorescence signals only in the presence of dual targets, and there is no response from single or interfering miRNAs. In actual serum samples, the spiked recoveries of miR-21 and miR-155 were 92%∼100.69% and 96.78%∼100.66%, respectively, with relative standard deviations of less than 7%. In summary, this sensing platform has the merits of easy operation, no need for enzyme amplification, and a low background signal. It demonstrates good accuracy and stability in intricate biological matrices, offering a promising technological approach for early identification, progression assessment, and precise diagnosis of gliomas.
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ACS Nano
·
2026
·
IF 17.3
Yutao Yang,Feifei Chen,Xiachu Xiao,Jianru Wang,Xiang Zhang,Borui Jiang,Yuxiang Xin,Zhitong Zhou,Zhengzheng Liu,Jiang Tang,Jiajun Luo,Zhuolei Zhang
Soft-lattice nanocrystal photon management hinges on controlling relaxation branching, diverting excitations from interfacial losses into radiative pathways. CsPbCl3:Yb3+ quantum cutting benchmarks this, but is still constrained by surface trapping, suboptimal Yb-pair branching energetics, and limited thermal/environmental stability. Here we implement a (2-bromoethyl)trimethylammonium bromide (BETAB)-enabled passivation strategy with annealing-triggered gradient halide reconstruction. BETAB replaces OA/OAm to reduce surface losses, while mild annealing activates ligand-associated Br– as a local reservoir to drive Br– in-diffusion with Cl– counter-migration, writing a continuous radial Cl/Br gradient (Br-rich interior). The graded halide landscape suppresses interfacial quenching and creates a radial band-edge bias that funnels excitations into the QC pathway, accelerating exciton-to-Yb3+ transfer. Consequently, QC PLQY increases stepwise from 84.7% (pristine) to 125.4% (BETAB-treated) and 155.2% (annealed). Integrated as spectral-conversion films on Si photodetectors, the treated NCs enable 200–1100 nm detection with responsivity up to 0.5 A W–1, EQE of 64.17%, and D* >1.02 × 1012 Jones (300–1100 nm) and 4.8 × 1011 Jones (200–300 nm), delivering clear ultrabroadband imaging in 7 × 7 arrays. The reconstructed NCs further show ATQ-like behavior (134% at ∼333 K) and improved aging stability (86.1% retention after 60 days vs 29.2% for pristine). Overall, ligand-enabled gradient writing reroutes relaxation for robust photon management.
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Food Bioscience
·
2026
·
IF 6.2
Huilin Zhao,Zhaoxuan Fan,Shan Shang,Donghong Liu,Lei Qin,Xuhui Huang
Replicating the authentic flavor profile of cell-cultured seafood remains a critical bottleneck, as current models predominantly based on monocultured myoblasts inherently lack the essential lipid-derived flavor precursors found in natural fish. This study constructed a cell-cultured fish meat (CM) model to investigate the flavor formation mechanisms driven by thermal interactions between the non-lipid cellular framework and exogenous fatty acids (oleic acid: OA; docosahexaenoic acid: DHA). Utilizing electronic nose and HS-SPME-GC-MS coupled with partial least-squares regression (PLS-R), the study revealed distinct flavor modulation pathways. The addition of OA significantly promoted the generation of methyl-pyrazine and alkyl furans, suggesting that OA oxidation intermediates triggered Strecker degradation with matrix proteins to construct a “lipid-derived aroma profile” backbone. Conversely, DHA specifically enriched unsaturated aldehydes and ketones (e.g., 4-heptenal, (E,E)-2,4-heptadienal) alongside 5-ethyl-2-methyl-pyridine, effectively imparting the characteristic “seafood-like aroma”. Furthermore, spatial separation in PLS-R demonstrated that the CM matrix exhibited a non-additive interaction with lipids:it specifically directed OA oxidation intermediates toward Strecker degradation to construct a lipid-derived aroma backbone, while selectively entrapping highly reactive DHA-derived unsaturated aldehydes to retain a balanced seafood-like profile. The cellular network acted as interactive microenvironments, exhibiting a modulating the release effect on highly reactive secondary oxidation products. This study elucidated the differential volatile generation pathways and controlled-release behaviors between the cellular matrix and specific lipids, providing theoretical insights into the targeted flavor modulation of thermally processed cell-cultured seafood.
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JOURNAL OF NANOBIOTECHNOLOGY
·
2026
·
IF 15
Deng Xu,Xie Xixiang,Zhou Xing,Jiang Lanfang,Zhu Tao,Su Rixiang,Chen Chunmei,Chen Wan,Chen Chunxia
The therapeutic efficacy of ischemic stroke (IS) treatment is severely limited by insufficient accumulation of therapeutic agents within ischemic lesions and persistent secondary injury after ischemia–reperfusion. Herein, we report a cRGD-functionalized exosome-based nanoplatform that enhances ischemic lesion-associated accumulation and antioxidative neuroprotection for the treatment of IS. Neural stem cell-derived exosomes were functionalized with cyclic RGD peptides (cRGD) and subsequently loaded with Mn₃O₄ nanoparticles to construct a hybrid nanosystem (cRGD-Exo@Mn₃O₄). The engineered exosomes preserve intrinsic brain tropism, while cRGD modification promotes preferential accumulation in ischemic regions, potentially through interaction with α v β 3 integrin that is upregulated in ischemic lesions. The incorporated Mn₃O₄ nanoparticles confer robust reactive oxygen species (ROS) scavenging capability, thereby mitigating oxidative stress in ischemic microenvironments. In vitro and in vivo studies demonstrate that cRGD-Exo@Mn₃O₄ exhibits enhanced accumulation in ischemic regions compared with non-modified counterparts. The nanosystem effectively attenuates oxidative stress and neuroinflammation, leading to reduced infarct volume, alleviation of cerebral edema, and improved neurological function in MCAO/R mice. Mechanistically, transcriptomic analysis suggests that the therapeutic effects are associated with modulation of inflammation-and cell death-related pathways, including suppression of the RIPK1/RIPK3/MLKL signaling cascade. Collectively, this study presents a rationally designed exosome-based nanoplatform integrating ischemic lesion-associated accumulation with ROS-scavenging capability. Graphical abstract
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MICROCHIMICA ACTA
·
2026
·Vol. 193
·期 9
·612
·
IF 5.4
Zhang Ning,Hu Xuelian,Guo Shuaijie,Lu Yiwei,Tang Yiwei,Wang Shuo,Ma Tianyi
Multi-modal sensing platforms have gained significant attention due to enhanced accuracy and self-calibration capabilities, particularly within complex matrices. Targeting the demand for the real-time detection of the food spoilage marker hydrogen sulfide (H 2 S), we introduce a triple-mode sensing platform engineered via 3,4-dihydroxyhydrocinnamic-acid-directed interfacial assembly of flower-like MOF@UCNPs heterostructures that synergize intense up-conversion luminescence with potent peroxidase-mimetic activity. Sulfide selectively coordinates with the Cu 2+ nodes embedded in the MOF, concurrently (i) shutting down nanozyme catalysis, (ii) restoring up-conversion emission, and (iii) attenuating UV–vis absorbance; complementary RGB alterations captured by a smartphone furnish the third read-out. The assay delivers limits of detection of 0.06 μM (fluorescence), 0.22 μM (absorbance) and 0.90 μM (RGB imaging) with excellent linearity, and achieves satisfactory recoveries in complex food matrices. By tracking H 2 S released from meat and eggs stored at different temperatures, real-time freshness assessment is realized on a smartphone. This work not only provides a robust food freshness monitoring tool but also offers a versatile blueprint for rational design of multifunctional nanomaterials toward point-of-need analyte detection. Graphical
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危险品化学品经营许可证（带存储）