ANALYTICAL CHEMISTRY
·
2026
·
IF 7.3
Bei Xu,Yun-Dong Yin,Lei Yang,Rui Shi,Xi-Tong Song,Zhi-Yuan Gu
The host–guest nanopore analysis method provided an avenue for hydrophobic analytes detection. However, the fixed cavity of conventional rigid hosts restricted the size range of detectable analytes, thereby partly limiting their further development. Herein, an organic clip (OC) was used as a flexible host to enhance the host–guest nanopore method in sensing hydrophobic drugs with various sizes. With the help of OC-assisted WT α-HL nanopores, differently sized hydrophobic drugs were detected and displayed distinguishable Level 2 signals, offering an effective approach to accomplish “one for more” analysis for hydrophobic analytes with various sizes. To explore the resolution of this method, the OC-assisted nanopore method was further used to simultaneously identify structurally similar antibiotics, including enoxacin, enrofloxacin, and moxifloxacin. Assisted by a machine learning algorithm, the validation accuracy for these three antibiotics reached up to 96.1%. Furthermore, the calibration curve for moxifloxacin was built based on the nanopore event frequency, through which moxifloxacin in commercial pharmaceuticals was accurately quantified. The OC-assisted nanopore method displayed the capability to extend the detection range across analyte sizes and demonstrated good resolution in distinguishing antibiotics with similar structures.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Reaction Chemistry & Engineering
·
2026
·
IF 2.9
Xiang Li,Saier Liu,Minjing Shang,Yuanhai Su
As an important chemical, benzaldehyde (BzH) can be synthesized by oxidizing dibenzyl ether (DBE) with nitric acid (HNO3). This is an environmentally friendly and chlorine-free production process, but it has problems such as intense in-situ gas generation, low space-time yield and safety issues. This study developed a safe and efficient continuous-flow synthesis method using a packed-bed microreactor. Five critical parameters including reaction residence time, glass bead particle size, temperature, oxidant concentration, and initiator dosage were systematically investigated. Under optimal conditions (T = 85℃, d = 104.5 μm, HNO3 eq = 3 and NaNO2 eq = 0.009), the conversion of DBE and the yield of BzH reached 80.11% and 96.35% after 17.92 min. The space-time yield was twice that of capillary microreactor and 40 times that of batch reactor. The reasons for in-situ gas production in capillary microreactors and its negative impacts were explored. A kinetic model was developed, providing significant theoretical insights and practical value for better understanding the oxidation process and optimizing the process parameters.
✓ 已验证
产品关联
DOI
高影响因子
Waste and Biomass Valorization
·
2026
·
IF 3.1
Huang Yue,Li Lifeng,Ruan Tao,Ouyang Xinping
The catalytic conversion of lignin derivatives into specific chemicals represents a key pathway for achieving high-valued utilization of biomass. A new Ag–Co 0 /Fe 0.04 Co 0.96 O catalyst was constructed for the selective demethoxylation of vanillic acid derived from lignin depolymerization to produce p-Hydroxybenzoic acid. Compared to Ag–Co 0 /CoO, Fe doping suppressed Co reduction, endowing the Ag–Co 0 /Fe 0.04 Co 0.96 O catalyst with suitable hydrogenation activity and more abundant acidic sites. The hydrogen spillover effect inhibited decarboxylation, dehydroxylation, and benzene ring hydrogenation during the demethoxylation reaction. Oxyphilic Fe species changed the adsorption geometry of vanillic acid from parallel adsorption into twist configuration, avoiding the hydrogenation of benzene ring, and thereby improving the demethoxylation selectivity to p-Hydroxybenzoic acid. By optimizing catalyst preparation and reaction conditions to minimize decarboxylation and over-hydrogenation byproducts, the Ag–Co 0 /Fe 0.04 Co 0.96 O catalyst contributed to a 98.52% conversion of vanillic acid and a 89.62% selectivity to p-Hydroxybenzoic acid under 0.4 MPa H 2 , 0.4 MPa CO 2 at 220 °C for 2 h. This research provided a theoretical foundation and practical guidance for the catalytic demethoxylation of phenolic acids, offering new insights into high-valued utilization pathways for biomass. Graphical
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2025
·
IF 2.5
Hong Zhang,Wenlong Lu,Chen Li,Xinyu Chen,Lei Wang,Hui Wan,Guofeng Guan
In this study, Rh supported on SiO2 was modified with Zr for the first time to investigate its catalytic performance in propylene hydroformylation. The RhZr/SiO2 catalyst exhibits a butyraldehyde selectivity of over 90% along with a 2.7-fold enhancement in propylene conversion compared to the unmodified catalyst, outperforming previously reported Co- and K-promoted systems. XPS characterization, combined with differential charge density calculations and Bader charge analysis, revealed that the introduction of Zr reduced the electron density around Rh, which facilitates CO adsorption on Rh and thereby promotes the formation of more active HRh(CO)x species. This conclusion is further supported by CO adsorption energy calculations. Under optimized reaction conditions (20 mL toluene solvent, 0.4 g RhZr/SiO2 catalyst with ultralow Rh loading of 0.02 wt%, 1.5 g propene, 100 °C, 4 MPa syngas pressure, 4 h), the catalytic system achieved remarkable performance: 75.1% propene conversion, 96.7% butyraldehyde selectivity, and a normal/iso (n/i) ratio of 0.9. Notably, the system exhibited an exceptional intrinsic activity (TOF = 8838 h−1), surpassing all reported ligand-free heterogeneous Rh-based catalysts in recent years. The present work provides an effective strategy for designing modified Rh-based heterogeneous catalysts with ultralow metal loading for hydroformylation applications.
✓ 已验证
产品关联
DOI
高影响因子
Coatings
·
2025
·Vol. 15
·期 7
·745
·
IF 2.8
Wudi Zhang,Zian Wang,Zhixuan Zhao,Xuan Zhou,Lixin Wu,Zixiang Weng
Anti-icing glass is particularly important for applications where ice formation can pose safety risks or impair functionality. The challenge of anti-icing modification for glass lies in maintaining water repellency while addressing the issue of transparency and durability. In this work, leveraging the robustness and wear resistance of inorganic/organic composite materials, a highly transparent coating, with strong adhesive properties to glass substrates and repellency to liquids has been developed. Briefly, 3-glycidoxypropyl polyhedral oligomeric silsesquioxane (GPOSS) is employed as a precursor to fabricate a high-strength, high-transparency coating through modification with acrylic acid and perfluorooctyl acrylate. The inorganic component imparts strength and wear resistance to the coating, while the organic component provides hydrophobic and near oleophobic features. Furthermore, a custom-built mechanical test instrument evaluated the absolute value of the de-icing shear force. The results reveal that at −20 °C, the fluorinated modified coating only exhibit a minimum de-icing pressure of 40.3 kPa, which is 75% lower than the unmodified glass substrate. As-prepared coating exhibits a transmittance of up to 99% and can endure a high-pressure water impact of 30 kPa for 1 min without cracking. Compared to existing anti-icing coating methods, the core innovation of the fluorinated GPOSS-based coating developed in this study lies in its inorganic/organic composite structure, which simultaneously achieves high transparency, mechanical durability, and enhanced anti-icing performance.
✓ 已验证
产品关联
DOI
高影响因子
CATALYSIS LETTERS
·
2025
·Vol. 155
·期 11
·1-18
·
IF 2.4
Zheng Chenyu,Sun Dayu,Gan Jingyi,Wang Rui,Gao Lijing,Wei Ruiping,Xiao Guomin
Lignin, a promising sustainable biopolymer, exhibits immense potential as a renewable feedstock for aromatic chemicals and advanced materials, offering a green alternative to fossil resources. However, its complex aromatic structure and recalcitrant β-O-4 ether bond pose significant challenges for efficient depolymerization. In this study, a series of Ce-modified Cu-Ni-Al layered double hydroxide (LDH) catalysts (CuNiAlCe x ) were designed for the catalytic transfer hydrogenolysis (CTH) of enzymatic hydrolysis lignin (EHL) using ethanol as a hydrogen donor, aiming to produce low-molecular-weight lignin oil (LO) enriched with phenolic hydroxyl groups. Structural and surface analyses revealed that Ce modification enhanced oxygen vacancy concentration through dynamic Ce 3+ /Ce 4+ redox cycling and optimized acid site distribution, synergistically facilitating C-O bond cleavage. The highest LO yield of 71.8% was attained under optimized reaction parameters, accompanied by a marked reduction in molecular weight and concurrent increases in phenolic hydroxyl and carboxyl groups. GC-MS analysis identified diverse aromatic monomers (total yield: 21.34%), predominantly guaiacyl derivatives. This study reveals the synergistic interaction between oxygen vacancies and acid sites in CuNiAlCe x catalysts, providing a green strategy for the selective valorization of lignin into aromatic compounds, thereby advancing sustainable biorefinery technology. Graphical
✓ 已验证
产品关联
DOI
高影响因子
LANGMUIR
·
2025
·
IF 3.9
Yue Yang,Kehan Huang,Yuankui Peng,Hongyan Xiao,Wangjing Ma,Lei Zhang,Lu Zhang
The interfacial arrangement of surfactant molecules dictates the properties of adsorption films, rendering the molecular adsorption mechanisms fundamentally critical. This study integrates interfacial dilational rheology with molecular dynamics simulation to unravel the adsorption mechanism of renewable sorbitol-alkylamine surfactant (SAAS-C12) at air/water (A/W) and n-decane/water (D/W) interfaces. We report the first discovery that hydrogen-bond switching governs the precise modulation of interfacial film strength: at the A/W interface, the transition from intramolecular hydrogen-bonded rings (low-concentration, irreversible adsorption) to intermolecular hydrogen-bonded networks (high-concentration, reversible adsorption) drives a distinctive bimodal dilational modulus trend while confining relaxation processes to slow molecular rearrangement. At the D/W interface, n-decane molecules weaken the interaction between surfactant alkyl chains by competing with surfactant molecules via van der Waals forces, converting the high-concentration modulus maximum to a gradual-decay plateau and concurrently redirecting dominant relaxation toward rapid diffusion exchange. Clarifying the mechanism of the interfacial dilational modulus dominated by hydrogen bonds helps to design green surfactants with good foam performance, showing promise for sustainable applications in the food industry, pharmaceutical delivery, and enhanced oil recovery.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FLUID PHASE EQUILIBRIA
·
2025
·
IF 2.7
Tao Jia,Jinpeng Yang,Jia Yu
Knowledge of the accurate pρTx behavior of hydrocarbon mixtures at different temperatures and pressures is indispensable for simulating reservoir behavior, optimizing recovery processes, and predicting the thermodynamic properties. The compressed liquid densities of n -pentane(1) + n -decane(2) binary mixtures with mole fraction x 1 = 0.1024, 0.2978, 0.5145, 0.7036, and 0.9113 were measured using a vibrating tube densimeter at temperatures from 283 K to 363 K, and pressures up to 100 MPa. The relative uncertainty for density measurement of n -pentane + n -decane binary mixtures of 0.99 mole fraction purity is 0.1%. The densities of binary mixtures were correlated with the modified Tait equation, and the absolute average deviations of the experimental and calculated values were 0.005%, 0.005%, 0.006%, 0.008%, and 0.009%, respectively. In addition, the isothermal compressibility, the isobaric thermal expansivity, and excess molar volume were calculated from experimental densities.
✓ 已验证
产品关联
DOI
高影响因子
Nature Communications
·
2025
·Vol. 16
·期 1
·1-12
·
IF 15.7
Yin Yun-Dong,Zhang Yu-Wei,Song Xi-Tong,Hu Jun,Chen Yu-Heng,Lai Wen-Chuan,Li Ya-Fei,Gu Zhi-Yuan
High-resolution nanopore analysis technology relies on the design of novel transmembrane protein platforms. Traditional barrel-shaped protein channels are preferred for constructing nanopore sensors, which may miss protein candidates in non-barrel structures. Here, we demonstrate the globular ferritin displays excellent membrane-insertion capacity and stable transmembrane ionic current owing to its hydrophobic four-fold channels and hydrophilic three-fold channels. The ionic current rectification and voltage-gating characteristics are discovered in single-ferritin ionic current measurement. Notably, the ferritin is used as a nanopore sensor, by which we achieve the high resolution discrimination of L-cysteine, L-homocysteine, and cysteine-containing dipeptides with the assistance of equivalent Cu 2+ . The mechanistic studies by multiple controlled experiments and quantum mechanics/all-atom/coarse-grained multiscale MD simulations reveal that analytes are synergistically captured by His114, Cys126, and Glu130 within C3 channel, causing the current blockage signals. The promising ferritin nanopore sensor provides a guide to discovering new protein nanopores without shape restrictions.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Chemical Engineering and Processing-Process Intensification
·
2026
·
IF 4.2
Haodong Chu,Mengdi Li,Weichen Zhao,Qingmao Yang,Chun Shen,Tianwei Tan
Production of 5-chloromethylfurfural (CMF) from fructose conducted in two-liquid phase system has achieved a considerable CMF yield. However, correlation between extraction process and CMF yield has not been reported yet. Herein, we found quantitative relation between interfacial specific area ( a ), extraction efficiency of 5-hydroxymethylfurfural (HMF) (E HMF ),a significant precursor of CMF and selectivity of CMF (S CMF ) in the microreactor. First, we systematically investigated the impact of flow rate ratio of two phases ( F C /F D ), total fluid velocity ( u ) and residence time on S CMF and E HMF . It turned out that both F C /F D and u had a significant impact on S CMF and E HMF . In addition, both u and F C /F D had a significant impact on interfacial specific area ( a ). As u varied, we fitted and observed a linear relation between u & a (R 2 =0.994), a & E HMF (R 2 =0.997) and E HMF & S CMF (R 2 =0.999). It indicated that CMF selectivity could be controlled by HMF extraction under certain conditions. Based on these results, we proposed a strategy for obtaining high CMF productivity from fructose in the microreactor. 93.9% CMF yield (11 g/L fructose concentration) and 89.9% CMF yield (110 g/L fructose concentration) were obtained. To the best of our knowledge, this work first proposes coordination between reaction and extraction in CMF production.
✓ 已验证
产品关联
DOI
高影响因子
BIOMASS & BIOENERGY
·
2026
·
IF 7
Peng Zheng,Wuyu Wang,Wenqin Hu,Qi Zhang,Xinghua Zhang,Longlong Ma,Lungang Chen,Jianguo Liu
Carbon-based solid acid catalysts have widespread applications in biodiesel production from feedstocks with high free fatty acid. However, developing high-performance and cost-effective catalysts through the selection of appropriate carbon sources and optimized preparation methods remains a key focus of research. Herein, we report a mesoporous carbon-based catalyst, ZnC1000@SO 3 H, synthesized from zinc citrate via in-situ Zn self-activation and diazotization. Zinc citrate serves as a low-cost precursor generates ZnO templates during carbonization, facilitating highly porous structures without additional activators. The catalyst was characterized using BET, EA, XRD, TGA, SEM, FTIR, and XPS, while the products were analyzed with GC and GC-MS. ZnC1000@SO 3 H exhibits a high surface area of 720 m 2 /g, a pore volume of 1.48 cm 3 /g, and a -SO 3 H density of 2.43 mmol/g. These features endow ZnC1000@SO 3 H with outstanding catalytic performance for esterification of oleic acid as a modal reaction, achieving a biodiesel yield of 97.3% under Response Surface Method optimized conditions (Temperature: 80 °C, Methanol/oleic acid molar ratio: 9.24:1, Catalyst dosage: 4.12 wt%, Time: 1.67 h). Kinetic and thermodynamic analyses reveal that the activation energy (Ea) for the esterification catalyzed by ZnC1000@SO 3 H is 36.65 kJ/mol, with an enthalpy change (ΔH) of 33.85 kJ/mol and an entropy change (ΔS) of −147.04 J/(K·mol). ZnC1000@SO 3 H also exhibited excellent substrate applicability for soybean oil and soybean oil (30 wt% oleic acid), achieving biodiesel yields of 63% and 70%, respectively. The catalyst demonstrates remarkable reusability, retaining 80% yield after eight cycles. The cost of catalyst ($3.29/kg) indicates significant potential for commercial application.
✓ 已验证
产品关联
DOI
高影响因子
Journal of Analysis and Testing
·
2026
·
IF 7
Lu Heng,Chen Jingru,Zhang Maosheng,Guo Liangqia
Microplastics (MPs) are emerging pollutants, considered one of the most serious threats to the ecosystem and human health. Nile Red (NR) is the most widely used dye for visualizing MPs. However, NR staining is affected by natural organic materials and shows weak fluorescence for certain types of MPs, such as polyamide (PA) and polyvinyl chloride (PVC), as well as MPs with fiber morphology. Herein, a rapid, universal staining method for visualizing MPs was proposed, using CsPbBr 3 perovskite nanocrystals (NCs) as a fluorescent dye synthesized by natural deep eutectic solvents (NADESs) as solvents and surface ligands (CsPbBr 3 @NADESs NCs). The staining method proved to be highly effective for common MPs, including PA and PVC MPs. Moreover, natural organic substances, such as cellulose, lignin, mussel shell, chitin, clam shell, shrimp shell, humic acid, and sand grains, could not be stained by CsPbBr 3 @NADESs NCs, which allowed MPs to stand out for visual detection even that the environmental samples were incompletely pre-treated. This study demonstrated CsPbBr 3 @NADESs NCs as a promising fluorescent dye for visual detection of MPs in environmental samples.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）