International Journal of Environmental Science and Technology
·
2019
·Vol. 16
·期 12
·7705-7714
·
IF 2.031
Wu H.,Sun J.,Zhou C.,Yang H.
The introduction of additives into desulfurization slurry may inhibit the mercury re-emission from slurry and improve the stabilization of mercury in slurry. In this paper, the effect of common additives, such as sodium sulfide (Na 2 S), 2,4,6-trimercaptotriazine trisodium (TMT-18), sodium dithiocarbamate (DTCR-2) and Fenton reagent, on mercury distribution in gas–liquid–solid phase was investigated under typical operating conditions. Meanwhile, the effect of different additive dosages on the inhibition performance of mercury re-emission was studied. Furthermore, the inhibition mechanisms of different additives were also discussed. The experimental results showed that Na 2 S, TMT-18, DTCR-2 and Fenton reagent could inhibit the mercury re-emission from desulfurization slurry and some mercury that might reemit into the gas phase before would be restrained in the solid phase. For additives such as Na 2 S, TMT-18 and DTCR-2, with the increase in additive dosages, the inhibition performances of mercury re-emission were improved, but the enhancing effects tended to level off. More mercury could be restrained in the solid phase by forming HgS, Hg-TMT and Hg-DTCR. However, for additives such as Fenton reagent, the inhibition performance of mercury re-emission was first increased and then decreased with the proportion of Fe 2+ and H 2 O 2 in Fenton reagent increasing. There existed an optimal proportion. The oxygenated free radical generated by Fenton reagent with Fe 2+ as catalysis was the main reason for the inhibition of mercury re-emission, and more mercury would be oxidized and then restrained in solid phase due to the formation of HgSO 4 and Fe(OH) 3 .
研究领域:
环境工程
·
化学工程
·
环境科学
✓ 已验证
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Mengyao Chen,Jingxian Yang,Lulu Zhou,Xiaochun Hu,Chunhui Wang,Keke Chai,Ruihao Li,Lei Feng,Yanting Sun,Chunyan Dong,Shuo Shi
Integrating chemodynamic therapy (CDT) and photodynamic therapy (PDT) into one nanoplatform can produce much more reactive oxygen species (ROS) for tumor therapy. Nevertheless, it is still a great challenge to selectively generate sufficient ROS in tumor regions. Meanwhile, CDT and PDT are restricted by insufficient H2O2 content in the tumor as well as by the limited tumor tissue penetration of the light source. In this study, a smart pH/ROS-responsive nanoplatform, Fe2+@UCM-BBD, is rationally designed for tumor combination therapy. The acidic microenvironment can induce the pH-responsive release of doxorubicin (DOX), which can induce tumor apoptosis through DNA damage. Beyond that, DOX can promote the production of H2O2, providing sufficient materials for CDT. Of note, upconversion nanoparticles at the core can convert the 980 nm light to red and green light, which are used to activate Ce6 to produce singlet oxygen (1O2) and achieve upconversion luminescence imaging, respectively. Then, the ROS-responsive linker bis-(alkylthio)alkene is cleaved by 1O2, resulting in the release of Fenton reagent (Fe2+) to realize CDT. Taken together, Fe2+@UCM-BBD exhibits on-demand therapeutic reagent release capability, excellent biocompatibility, and remarkable tumor inhibition ability via synergistic chemo/photodynamic/chemodynamic combination therapy.
研究领域:
癌症治疗
·
纳米技术
·
药学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
San-Jun Shi,Rong-Fu Huang,Zi-Yan Fan
Development of rapid and sensitive methods for screening of large number of chemical pollutants with potential genotoxicity is in urgent demands. In this work, we reported a chemical genotoxicity sensor based on the lateral flow strip (LFS) quantification of the 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodGuo). The proposed sensing strategy introduced human 8-oxoguanine DNA glycosylase (hOGG 1) and human apyrimidinic endonuclease (APE 1) to convert 8-oxodGuo to strand break. Then, the DNA conjugated gold nanoparticles (AuNPs) complexes could not be captured on test line (T-line), showing visible red color fading. Additionally, the mean grey value of the optical density in the T-line zone was analyzed by using a mobile phone camera and Image J software to quantify 8-oxodGuo. Under the optimized experimental conditions, the LFS DNA biosensor could detect the lowest concentration of 8-oxodGuo down to 0.2 pmol. To demonstrate its universal applications, in vitro generation of 8-oxodGuo by Rose Bengal under irradiation and Fe 2+ -mediated Fenton reagent were successfully measured. The detection limit of oxidative DNA damage induced by Rose Bengal or Fenton reagent could be down to 0.01 μM or 1 nM Fe 2+ /4 nM H 2 O 2 , respectively. The 10-fold higher sensitivity for Fenton reagent was attributed to much more severe damage than Rose Bengal, producing both DNA strand break and nucleobases conversion. The results demonstrated that the LFS DNA biosensor could detect oxidative DNA damage for the first time, showing its potential application for assessment of the genotoxicity of abundant chemical pollutants.
研究领域:
分析化学
·
环境科学
·
生物技术
·
毒理学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2016
·
IF 5.557
Hai Qiang Li,Xue Jiao Liu,Jingmei Xu,Da Xu,Hongzhe Ni,Shuang Wang,Zhe Wang
A series of triazole-grafted sulfonated poly(arylene ether ketone sulfone)s (SPTs) were fabricated via an amide coupling reaction between 3-amino-1,2,4-triazole and carboxylic acid group. The degree of sulfonation (DS) was set to 80% for preventing excessive swelling. The chemical structures of synthesized polymers were characterized by Fourier transform infrared spectroscopy (FT-IR) and 1 H NMR spectroscopy . The triazole group affected the properties of membranes dramatically. Increasing the triazole group content was conductive to promoting the thermal property and oxidative stability. And all SPT membranes retained above 92% of their weight after the test in Fenton's reagent at 80 °C for 1 h. The swelling ratio of SPT-3 membrane was only 12.66% and it was lower than that of C-SPAEKS-3 membrane at 100 °C. It was also found that the proton conductivity was distinctly improved by introducing triazole groups and the SPT-4 membrane exhibited a proton conductivity of 0.166 S cm −1 at 120 °C, which was larger than that of Nafion 117. In addition, all SPT membranes showed higher proton conductivity when compared with C-SPAEKS-3 membranes over the range of relative humidity from 20% to 90% at 80 °C.
研究领域:
材料科学
·
化学
·
高分子科学
·
燃料电池
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Ning Liu,Shuguang Bi,Ying Ou,Hai Liu,Yi Zhang,Chunli Gong
Proton exchange membranes with high ionic conductivity and good chemical stability are critical for achieving high power density and long lifespan of direct methanol cells (DMFCs). Herein, a zwitterionic molecule was grafted onto the surface of polyvinylidene fluoride (PVDF) nanofibers to obtain functionalized PVDF porous substrate (SBMA-PDA@PVDF). Then, sulfonated poly(ether ether ketone) (SPEEK) was filled into the pores of SBMA-PDA@PVDF, and further ionic cross-linked via H 2 SO 4 to prepare the composite membrane (SBMA-PDA@PVDF/SPEEK). The basic groups on the zwitterionic interface could not only establish ionic cross-linking with SPEEK to increase chemical stability and reduce swelling, but also serve as the adsorption sites for subsequent H 2 SO 4 cross-linking to significantly enhance proton conductivity. Super-high proton conductivity (165.34 mS cm −1 , 80 °C) was achieved for the membrane, which was 2.12 times higher than that of the pure SPEEK. Moreover, the SBMA-PDA@PVDF/SPEEK membrane exhibited remarkably improved oxidative stability of 91.6 % mass retention after soaking in Fenton’s agent for 12 h, while pure SPEEK completely decomposed. Satisfactorily, the DMFC assembled with SBMA-PDA@PVDF/SPEEK exhibited a peak power density of 99.01 mW cm −2 , which was twice as much as that of commercial Nafion 212 (48.88 mW cm −2 ). After 235 h durability test, only 11 % voltage loss was observed.
研究领域:
材料科学
·
电化学
·
能源材料
·
燃料电池技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）