JOURNAL OF CHROMATOGRAPHY A
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2024
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IF 3.8
Wenhui Lu,Chunli Ding,Mingshuo Zhu
The process of globalization and industrialization has resulted in a rise in the theft of coal and other related products, thereby becoming a focal point for forensic science. This situation has engendered an escalated demand for effective detection and monitoring technologies. The precise identification of coal trace evidence presents a challenge with current methods, owing to its minute quantity, fine texture, and intricate composition. In this study, we integrated machine learning with the identification of volatiles to accurately differentiate coal geographical origins through the application of headspace-gas chromatography-ion mobility spectrometry (HS-GC-IMS). The topographic distribution of volatiles in coals was visually depicted to elucidate the subtle distinctions through spectra and fingerprint analysis. Additionally, four supervised machine learning algorithms were developed to quantitatively predict the geographical origins of natural coals utilizing the HS-GC-IMS dataset, and these were subsequently compared with unsupervised models. Remarkable volatile compounds were identified through the quantitative analysis and optimal Random Forest model, which offered a rapid readout and achieved an average accuracy of 100 % in coal identification. Our findings indicate that the integration of HS-GC-IMS and machine learning is anticipated to enhance the efficiency and accuracy of coal geographical traceability, thereby providing a foundation for litigation and trials.
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PubMed
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Analytical Methods
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2025
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IF 2.6
Desen Su,Yunyun Zheng,Minmin Huang,Ziqiang Chen,Lisong Chen,Meizhen Chen,Qinghua Yao
Depending on the manufacturing process, Tieguanyin tea (TGY) is classified into three main groups, light flavor type (LFT), heavy flavor type (HFT), and stale flavor type (SFT). However, the compositions and contents of volatile compounds among TGY types were still unclear. This study aimed to develop an efficient method for the nonselective determination of volatile compounds in teas via direct-headspace injection coupled with gas chromatography mass spectrometry (DHI-GC-MS), and to perform a comprehensive comparison among these teas. One hundred and twelve volatile compounds belonging to 9 classes were identified. Among them, 33 common volatiles from 4 categories (aldehydes, alcohols, ketones, and acids) were the dominant volatiles and accounted for 71.5%, 73.0%, and 71.8% of the total amount in LFT, HFT, and SFT, respectively. E-Nerolidol, ethanol, acetic acid, and some volatiles with five and six-carbon chains were the key chemicals to distinguish three different TGY teas. With PLS-DA analysis, distinct differences among different groups were observed. The results generated from this study may offer valuable insights for better grading of TGY teas.
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NATURAL PRODUCT RESEARCH
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2018
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IF 1.928
Guo-Feng Mao,Xiao-Chang Mo,Hatem Fouad,Ghulam Abbas,Jian-Chu Mo
Utilisation of Anagrus nilaparvatae is a promising and effective method for planthoppers manipulation. Twenty-seven components of remote lemongrass (Cymbopogon distans) oil were identified by GC/MS and nine volatiles were selected for behavioural experiments. In this study, we noted that the remote lemongrass oil was attractive to female A. nilaparvatae at concentrations of 0.1 and 1 mg/L. α-Pinene, β-pinene, eucalyptol, carveol and D-carvone attracted female wasps in the dose-dependent bioassays. Blend 1 (a mixture of eucalyptol, D-carvone, carveol, α-pinene, and β-pinene with ratios of remote lemongrass oil volatiles of 625:80:11:5:3) attracted female wasps at 10 mg/L, while blend 2 (a mixture of the same five volatiles at the same loading ratio) attracted them at 0.1 and 1 mg/L. These results suggested that plant essential oils could be attractants for natural enemies to control pests. The ratios of volatiles in the mixtures affect the attractiveness of the synthetic mixtures.
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Food Chemistry-X
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2024
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IF 6.5
Yujiao Cheng,Leng Han,Linzi Shao,Hua Wang,Zheng Guo,Guijie Li
Pomelo flowers emit a strong fragrance and give aromatic odors. Volatile compounds from pomelo flowers were analyzed at three developmental stages and in the main organs by molecular sensory science. A total of 134 volatiles including 25 odorants, were analyzed by gas chromatography–mass spectrometry/pulsed flame photometric detector (GC–MS/PFPD) and multidimensional GC–MS/olfactory (MDGC–MS/O). The total volatile content varied among pomelo flowers at different developmental stages (stage-III > stage-II > stage-I) and among different organs of pomelo flowers (petal > pistil > stamen). Linalool was an important odorant with a high OAV, and floral/fruity comprised the predominant aroma profile. Four odorants, ethyl 2-methylbutanoate, linalool, β-myrcene, and 2-butenal, were selected based on variable importance in projection (VIP) values and contributed mainly to the discrimination of pomelo flowers at three different developmental stages. Linalool, β-myrcene, d -limonene, and ethyl hexanoate were potential markers for evaluating flavor differences in pomelo floral organs.
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FOOD RESEARCH INTERNATIONAL
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2024
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IF 7
Xinming Chen,Dandan Yang,Lin Huang,Mengqi Li,Jihai Gao,Can Liu,Xiaoming Bao,Zhizhi Huang,Jinhui Yang,Haozhou Huang,Dingkun Zhang,Runchun Xu
Frankincense is an important seasoning and spice known for its distinctive and intricate flavor profile. Considering the considerable variation in the aromatic quality of frankincense due to geographical origin, species diversity and cultivation conditions, frankincense from major global origins was characterized holistically for the first time. The electronic nose (E-nose) with headspace solid-phase microextraction gas chromatography–mass spectrometry (HS–SPME–GC–MS) and sensory evaluation were implemented to characterize the aroma components of 21 commercial varieties of frankincense from around the world. The results showed that a total of 149 volatile organic compounds (VOCs) of 10 categories were identified in frankincense, among which the numbers of alcohols, terpenes and esters compounds accounted for 22.15 %, 18.79 % and 15.44 % of the total VOCs of frankincense, respectively. The PLS-DA model effectively distinguished frankincense from Oman/Somalia and other origins. Furthermore, the study identified two differential VOCs with VIP > 1 in three Asian countries and five in six African countries. The total VOCs content and sensory characteristic score of “Lemon/Citrus” in Oman frankincense is significantly higher than other regions. The OAV results showed that 61 substances (e.g., Diacety, alpha-Pinene, Camphene, Myrcene) as key aroma compounds and OICS model indicated that p-Cymenol was found to contribute significantly to the citrus aroma in frankincense. This study identified the fundamental components of frankincense flavor and revealed different flavor descriptors of frankincense, which are crucial for reconstructing frankincense flavor and improving flavor quality.
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JOURNAL OF CHEMICAL AND ENGINEERING DATA
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2009
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IF 2.063
Dongwei Wei,Lishuo Wang,Chao Zhang
Solid−liquid equilibria have been measured for binary mixtures of 1,8-cineole with p-cymene, β-pinene, and camphene, respectively, using differential scanning calorimetry (DSC) over the whole composition concentration range. All three are simple eutectic systems. The eutectic point of the (1,8-cineole (1) + p-cymene (2)) mixture is at 200.0 K and x1 = 0.124, the (1,8-cineole (1) + β-pinene (2)) mixture at 205.6 K and x1 = 0.154, and the (1,8-cineole (1) + camphene (2)) mixture at 251.8 K and x1 = 0.582. An empirical equation of Ott and Goates was used for correlating the experimental data.
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Journal of Materials Chemistry B
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2025
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IF 5.7
Huajin Zhang,Fujun Liu,Junyilang Zhao,Yong Wang,Yuge Shen,Qiqi Li,Hui Luo,Yu Chen,Rong Li,Fan Zhu,Shuo Xie,Yinhao Wei,Xupeng Gou,Danling Hu,Zhengji Li,Hanshuo Yang
Chimeric antigen receptor T cell (CAR-T) therapy has shown remarkable promise in treating hematological malignancies. However, the ex vivo expansion of CAR-T cells is time-consuming, potentially impairing CAR-T cells function. Physiologically, T cell activation and proliferation occur within the lymph node (LN) paracortex, a dynamic environment structured by a three-dimensional (3D) reticular network (RN) that promotes cell migration and mediator delivery. Mimicking this physiological niche offers a compelling strategy to improve CAR-T cell expansion. Inspired by the structure of RN, we developed a biomimetic RN-like poriferous microsphere (PM) to establish a 3D culture platform optimized for both T cell and CAR-T cell proliferation. This engineered system not only significantly enhanced the proliferation rates of human T cells and CAR-T cells compared to conventional methods, but also preserved a higher proportion of central memory T cells (TCM) and reduced the expression of exhaustion markers (PD-1, TIM-3, and LAG-3). Moreover, CAR-T cells expanded in PMs exhibited superior anti-tumor efficacy in both ex vivo and in vivo models, which correlated with the enrichment of pathways associated with robust T cell function at the RNA level. Over all, this biomimetic platform addresses critical limitations in human T/CAR-T cell expansion, preserving cell function and improving therapeutic outcomes.
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POSTHARVEST BIOLOGY AND TECHNOLOGY
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2025
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IF 6.8
Yan Yang,Siying Liu,Yan Wang,Qin Yang,Baoan Wang,Yuting Zhang,Zaikang Tong,Junhong Zhang
The high susceptibility of apple fruit to Botryosphaeria dothidea severely limits their postharvest storage. Phoebe bournei essential oil has shown antimicrobial activity against microorganisms. However, its antiphytopathogenic fungal properties and mechanisms have not been thoroughly investigated.The study showed that Phoebe bournei wood essential oil (PWEO) had strong antifungal activity on B. dothidea and could effectively inhibit apple postharvest ring rot. Microscopic observation revealed that PWEO treatment significantly damaged the morphological structure of B. dothidea . PWEO compromised the integrity of the fungal cell membranes, leading to an increase in extracellular nucleic acids, proteins, and electrical conductivity, as confirmed by PI staining. Prolonged PWEO treatment led to a decrease in total lipid, ergostero and trehalose content but an increase in glycerol content. Fluorescent dye staining revealed that PWEO induced intracellular reactive oxygen species (ROS) accumulation leading to lipid peroxidation and mitochondrial membrane potential (MMP) disruption. PWEO also increased four antioxidant enzyme activities in apples. The weighted gene co-expression network analysis (WGCNA) analysis was used to screen out the genes associated with the physiological indexes as differential genes and quantitatively verified, and the results showed that PWEO significantly up-regulated the expression of glycoside hydrolase ( GH16 ), while down-regulating the expression of Chitin synthetase ( CHS ), β-1,3-glucan synthase ( FKS ), ergosterol synthase ( ERG28 ), multidrug-resistance-like protein B ( MdlB ), and superoxide dismutase ( SOD1 ) in B. dothidea . GC-MS analysis revealed that composition of PWEO was significantly different from the EOs of other tissues of P. bournei , and demonstrated that (-)-borneol, isoborneol, terpinen-4-ol, guiazulene and o -cymene contributed to the antifungal activity of PWEO. In summary, PWEO is a promising antifungal agent for controlling apple postharvest ring rot.
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JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
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2025
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IF 3.2
Liu Hongli,Peng Ziyang,Yuan Wenjin,Zhang Baojie,Chu Peng,Liu Yuhao,Xie Weiqiang,Tao Bingxin,Song Yao,Zu Wenjing,Yu Kun,Bian Chenghao
Mullite fiber aerogels are suitable for high-temperature insulation and other extreme environment applications due to their low density, excellent thermal stability, and low thermal conductivity. However, the elevated thermal conductivity at high temperatures and the limited mechanical strength confined its wider application. In this paper, mullite fibers/silicon carbide (SiC) composite aerogels were prepared by freeze-drying method with polycarbosilane (PCS) as a precursor. The SiC formed during the pyrolysis of PCS served as a high-temperature binder, which can form a tough three-dimensional network structure with mullite fibers. Benefit from the good infrared shielding property and high strength of SiC phase, the high-temperature insulation and mechanical properties of the aerogels were greatly improved. The lowest thermal conductivity of the mullite fibers/SiC aerogel can be 0.037 W·m −1 ·K −1 at room temperature and 0.067 W·m −1 ·K −1 at 1000 °C. Meanwhile the compressive strength can reach 0.31 MPa (10% strain). These favorable properties make it a very promising material in high temperature insulation applications. Graphical
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危险品化学品经营许可证（带存储）