INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2023
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IF 8.2
Qun Wang,Zhaomei Wang,Jun Song,Kangjie Xu,Wenni Tian,Xu Cai,Jiamei Mo,Yong Cao,Jie Xiao
A nanolipidcarrier (NLC) loaded homogalacturonan enriched pectin (citrus modified pectin, MCP4) hydrogel was designed as a novel colon inflammation site-specific oral delivery system for 6-gingerol (6G) (6G-NLC/MCP4 hydrogel) administration, and its colitis alleviation effect were investigated. 6G-NLC/MCP4 exhibited typical “cage-like” ultrastructure with 6G-NLC embedded in the hydrogel matrix as observed by cryoscanning electron microscope. And due to the homogalacturonan (HG) domain in MCP4 specifically combined with Galectin-3, which is overexpressed in the inflammatory region, the 6G-NLC/MCP4 hydrogel targeted to severe inflammatory region. Meanwhile, the prolonged-release characteristics of 6G-NLC provided sustained release of 6G in severe inflammatory regions. The matrix of hydrogel MCP4 and 6G achieved synergistic alleviation effects for colitis through NF-κB/NLRP3 axis. Specifically, 6G mainly regulated the NF-κB inflammatory pathway and inhibited the activity of NLRP3 protein, while MCP4 regulated the expression of Galectin-3 and peripheral clock gene Rev-Erbα/β to prevent the activation of inflammasome NLRP3.
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Food Packaging and Shelf Life
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2022
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IF 8.749
Haohe Huang,Chongxing Huang,Chenglong Xu,Ren Liu
Inspired by the water resistance and antibacterial adhesion of lotus leaves, an eco-friendly bionic film was prepared using polyvinyl alcohol/chitosan biomass composite film as the substrate and beeswax as the waxy layer. The effects of different spray components on the physicochemical and bacterial adhesion properties of the film were studied. The analysis results showed that the presence of beeswax and SiO 2 improved the UV barrier, WVP, and thermal properties. The FTIR spectroscopy and SEM results showed that the incorporation of beeswax and SiO 2 formed a fine bionic structure on and intermolecular hydrogen bonds with the surface of the film. Additionally, the biomimetic membrane exhibits appreciable superhydrophobicity (contact angle > 150°) and antibacterial adhesion. Therefore, the prepared film shows significant physicochemical properties and antibacterial adhesion and is a suitable antibacterial adhesive packaging material that extends the shelf life of fruits and vegetables.
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Foods
·
2022
·Vol. 11
·期 7
·1039
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IF 5.561
Meimiao Chen,Abdullah,Wenbo Wang,Jie Xiao
Double emulsions (W/O/W) with compartmentalized structures have attracted a lot of research interests due to their diverse applications in the food industry. Herein, oil phase of double emulsions was gelled with beeswax (BW), and the effects of BW mass ratios (0–8.0%) on the stability, oral sensation, and flavor release profile of the emulsions were investigated. Rheological tests revealed that the mechanical properties of double emulsions were dependent on the mass ratio of BW. With the increase in BW content, double emulsions showed a higher resistance against deformation, and lower friction coefficient with a smoother mouthfeel. Turbiscan analysis showed that the addition of BW improved the stability of double emulsions during a 14 days’ storage, under freeze–thawed, and osmotic pressure conditions, but it did not improve the heating stability of double emulsions. The addition of BW contributed to lower air-emulsion partition coefficients of flavor (2,3-diacetyl) compared to those without the addition of BW at 20 °C and 37 °C, respectively. Furthermore, the addition of BW and its mass ratio significantly altered the flavor release behavior during the open-bottle storage of double emulsions. The response value of 0% BW dropped sharply on the first day of opening storage, showing a burst release behavior. While a slow and sustained release behavior was observed in double emulsions with 8.0% BW. In conclusion, gelation of the intermediate oil phase of double emulsions significantly enhanced the stability of double emulsions with tunable oral sensation and flavor release by varying the mass ratio of beeswax.Keywords:Pickering double emulsions;gelation;beeswax;stability;oral sensation;flavor release
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FOOD HYDROCOLLOIDS
·
2022
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IF 11.504
Meimiao Chen,Wantong Li,Wenbo Wang,Yong Cao,Yaqi Lan,Qingrong Huang,Jie Xiao
Due to the unique multi-chamber structure of the double emulsion (DE), gelation different compartments of double emulsions with different gelling strength offers flexible control over their encapsulation and delivery properties. Herein, the aqueous or oil phase of DE was gelled with alginate or beeswax at different gelling strength, and the effects of gelation on the processing stability, rheological and tribological properties as well as the digestion profile of double emulsions were investigated. Gelation in each phase improved the stability of DE (0,0,0), with the oil or external aqueous phase gelation being more efficient in lifting the encapsulation stability after 14 days’ storage (increased from 67.50 ± 2.47% to 86–90% and 84–90%, respectively). Under processing conditions, the oil phase gelled DE was easily destabilized when subjected to heating treatment, but maintained better stability under freeze-thaw or osmotic pressure treatment compared to the internal and external water phase gelled ones. Gelation also actively regulated the rheological and tribological properties of DE, wherein gelation in internal water phase showed the least impact on the rheological properties, gelation in the external aqueous phase and oil phase exerted more significant influence on the viscosity and the tribological properties of DE, respectively. The external water phase gelled DE manifested the time-delayed digestion profile with only 8.09 ± 0.12% of internal marker release at the end of gastric digestion and the FFA release extent was decreased by 41.66% as compared to the DE (0,0,0). The present study offers a valuable guide for rational design of double emulsions with tailor-made processing stability, oral sensation and digestive characteristics.
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RADIATION PHYSICS AND CHEMISTRY
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2023
·
IF 2.9
Wenjing Liu,Xinrui Zhang,Hongbo Wang,Guorong Yang,Xiaoman Zhao,Jianhan Hong
The flexible X-ray protective materials are commonly made of lead rubber. They have heavy weight, high biological toxicity, poor flexibility and aging resistance. The "weak absorption zone" in the energy range of 40–88 keV threaten environmental safety and human health. Bi 2 O 3 -rubber based flexible X-ray protective materials were prepared by rubber production process. The micromorphology, shore hardness, specific gravity, mechanical properties and radiation protective properties were characterized and analyzed. The results showed that Bi 2 O 3 particles dispersed in natural rubber (R) matrix uniformly. The shore hardness of samples fluctuated between 41° and 46° with the increasing Bi 2 O 3 content, lower than the Level 1 index requirement of the hardness (≤80°) of lead-free composite protective materials. The specific gravity increased from 1.35 g/cm 3 to 2.38 g/cm 3 , which reduced approximately 34% comparing with the commercial protective materials containing Pb. The breaking strength and breaking elongation meet the index requirements in National standard GB 16757-2016. When Bi 2 O 3 content reached 300 parts, the highest lead equivalent and maximum shielding ratio were 0.3012 mmPb and 52.95% respectively. It meets the index requirement of lead equivalent of 0.25 mmPb≤Pb≤0.35 mmPb for the front sheet of protective clothing. The effective shielding range of the protective material R/Bi 2 O 3 (100/300) was mainly in the range of incident energy of 65∼100 keV and 164–250 keV, which covered the “weak absorption zone” of lead.
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Food Bioscience
·
2023
·
IF 5.2
Pengjing Zhang,Yuanda Sun,Yitong Hou,Haitao Wang,Mingqian Tan
Double emulsions (DEs), one of the most promising dispersion systems, have attracted much attention in the food industry. However, instability and the need for synthetic surfactants hinder the application of DEs. The development of clean-label DEs with good stability remains a challenge. Herein, novel DE gels (DEGs) with water-in-oil-in-water morphology were developed by combining multiple gelation and emulsification processes, which can stabilize the dispersion system without the synthetic surfactants used in conventional emulsions. Gelatin and beeswax were used to gelatinize the internal aqueous and oil phases respectively. Sodium caseinate acted as the external aqueous phase emulsifier, while a blend of gellan gum (GG) and sodium alginate (SA) was introduced to create DEGs. The networks formed by SA and GG in the water phase inhibited the movement of droplets in the emulsions and improved their stability. The DEGs can withstand up to five freeze-thaw cycles and at least 100 d of storage. In addition, the textural properties of DEGs were characterized and the results suggested that DEGs could be used as a cheese simulant. DEGs could be used as carriers for the co-delivery of phycocyanin and astaxanthin . Their encapsulation efficiency was greater than 90%. Furthermore, in vitro digestion showed that DEGs significantly improved the bioavailability of astaxanthin and phycocyanin, which increased from 18.5 ± 0.15% and 16.3 ± 0.45% to 43.2 ± 0.35% and 41.6 ± 0.5%, respectively. In conclusion, we have demonstrated a novel strategy for the preparation of clean-label DEGs, which could be used as a carrier for the co-delivery of hydrophilic and hydrophobic substances.
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2020
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IF 4.192
Qi Li,Quan Ma,Yilan Wu,Yan Li,Bin Li,Xiaogang Luo,Shilin Liu
As bio-based food packaging materials promise a more sustainable future, this work fabricated edible oleofilms by casting beeswax-in-water Pickering emulsions, which were formed by the physical hybrid particles of bacterial cellulose nanofibrils (BCNFs) and carboxymethyl chitosan (CCS) (BC/CCS). The emulsion droplet size was varied from 4 to 9 μm, and the emulsion index (EI) was all up to 100%. The obtained emulsions exhibited excellent long-term stability, and there was no change in the EI (100%) after the storage of the emulsion for 3 months. Moreover, the environmental temperature had almost no impact on the droplet size and EI of the emulsion. The mechanical properties of the oleofilms were significantly improved by enhancing the content of BC/CCS. There was also a visual reduction in the water vapor permeability (WVP) value, which was lower than 1.1 × 10–7 g·m–1·h–1·Pa–1. Furthermore, the obtained oleofilms exhibited a notable improvement in surface hydrophobicity, and surprisingly, it could be easily redispersed into water to recover back to the emulsion state without additional high energy mixing. This suggested that this edible oleofilm was prepared by a fully green method by casting Pickering emulsions stabilized by BC/CCS and could extend its application for the development of food-grade coating materials.
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LWT-FOOD SCIENCE AND TECHNOLOGY
·
2020
·
IF 4.006
Feilong Wei,Jianyin Miao,Huiyou Tan,Runqing Feng,Qianwang Zheng,Yong Cao,Yaqi Lan
In this study, the influence of crystal morphology and cooling temperature on the oxidative stability of oleogel-structured perilla oil emulsion was explored. The formation and distribution of the internal crystals were confirmed by differential scanning calorimetry and polarized light microscopy. All beeswax (BW) crystals existed in the internal phase while stearic acid (SA) crystals appeared in the aqueous phase as well. As the crystal grew, the HPMC/SDS emulsified layers were pierced, leading to release of the SA crystals into the aqueous phase with partial droplet flocculation. As a result, the physical and oxidative stability of the BW-structured emulsion was significantly better than that of SA-structured emulsion. The crystallinity of the emulsion increased with higher gelator concentration. The denser crystal network were more effective preventing the penetration of pro-oxidants into the internal phase, resulting in the stronger the oxidation stability. Processing methods with different cooling temperature affected more of the properties of bulk oleogels rather than the oleogel-structured emulsion for long-term storage. Overall, choosing a gelling agent that forms relatively small crystals and preparing an oleogel-structured emulsion with appropriate crystallinity can effectively improve the oxidative stability of structured emulsion with longer shelf life.
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FOOD CHEMISTRY
·
2020
·
IF 6.306
Bing Xie,Xingzhong Zhang,Xiaogang Luo,Yixiang Wang,Yan Li,Bin Li,Shilin Liu
In this work, novel edible coating films based on beeswax-in-water (O/W) Pickering emulsions had been investigated. The Pickering emulsions were stabilized with cellulose nanofibrils (CNFs)/carboxymethyl chitosan (CCS). The emulsions with a droplet diameter of around 10 μm had uniform particle size distribution, and the creaming stability was improved with the increasing the contents of CNFs in the complexes, rheological analysis demonstrated that the Pickering emulsions had an elastic gel-like network. Furthermore, free-standing films were obtained when the emulsions were dried at ambient condition, the tensile strength of the coating films could be 5.0 MPa at a strain of 2.2%, and the water vapor permeability (WVP) value was lower than 2 × 10 −7 g∙h −1 ∙m −1 ∙Pa −1 . Moreover, the coating films could inhibit the growth of typical spoilage organisms such as S. aureus or E. coli, it indicated that the coatings films would have promising applications in antiseptic and fresh keeping for berry fruits.
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ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Mengjie Chang,Simeng Fan,Runqiu Lu,Fei Tao,Facui Yang,Qian Han,Jun Liu,Peng Yang
A sunscreen offers indispensable skin protection against UV damage and related skin diseases. However, due to the poor interfacial stability of sunscreen coatings on the skin, the synthetic ingredients in sunscreen creams easily fall off and enter aquatic environments, causing large ecological hazards and skin protection failure. Herein, we tackle this issue by introducing amyloid-like protein aggregates into a sunscreen to noticeably enhance the interfacial robustness of sunscreen coatings on the skin. The synthesis of such an agent to suppress sunscreen leakage can be achieved by manipulating the phase transition of bovine serum albumin (BSA) in a mild aqueous solution at room temperature. The resulting phase-transitioned BSA (PTB) aggregates effectively entrap the sunscreen ingredients to generate a uniform cream coating on the skin with robust amyloid-mediated interfacial adhesion stability. With continuous flushing in aquatic environments, such as salt water and seawater, this PTB-modified sunscreen (PTB sunscreen) coated on the skin maintains a retention ratio as high as >92%, which is 2–10 times higher than those of commercially available sunscreen products. The high retention ratio of the PTB sunscreen in aquatic environments demonstrates the great potential of amyloid-like protein aggregates in the development of leakage-free sunscreens with low ecosystem hazards and long-lasting UV protection in aquatic environments.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Zhuangran Tuo,Yuanfeng Pan,Pingxiong Cai
Frequent oil spills have caused increasingly severe pollution of marine water bodies. As a result, exploring green and efficient aerogels to tackles oil pollution is in high demand. In this work, a unique strategy for preparing all-biomass aerogel was innovatively proposed. A series of all-biomass CW&BW@DCGA aerogels were successfully prepared by multiple dynamic covalent bonding, in which carboxymethyl chitosan (CMCS) as the substrate material, modified gelatin (Gel-ADH) as a reinforcing agent, and dialdehyde β-cyclodextrin (Da-β-CD) as a non-toxic cross-linking agent. The resulting aerogels were further hydrophobically modified with a green and natural wax blend consisting of carnauba wax (CW) and beeswax (BW). The experimental results demonstrated that incorporating Gel-ADH significantly improved the elastic properties of the materials. Specifically, when m(CMCS):m(Gel-ADH) = 7:3, the aerogel exhibited outstanding resilience, with 60 % compressive strain. In addition, CW&BW@DCGA displayed excellent hydrophobicity, boasting a water contact angle as high as 148.6°, and impressive absorption capacities ranging from 31.7 to 62.5 g/g towards different oils. Its adsorption capacity remained close to 70 % after 10 cycles, indicating favorable reusability. The dynamic absorption processes towards gasoline, diesel, and soybean oil were also well fitted with the pseudo-second-order kinetic model, suggesting that the process is primarily governed by chemisorption.
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Regenerative Biomaterials
·
2024
·
IF 5.6
Lin Qiaoxia,Zhang Yonggang,Chen Luhua,Zhang Haoyue,An Chuanfeng,Li Chengze,Wang Qifan,Song Jinhui,He Wei,Wang Huanan
Development of piezoelectric biomaterials with high piezoelectric performance, while possessing excellent flexibility, biocompatibility, and biodegradability still remains a great challenge. Herein, a flexible, biocompatible and biodegradable piezoelectric β-glycine-alginate-glycerol (Gly-Alg-Glycerol) film with excellent in vitro and in vivo sensing performance was developed. Remarkably, a single, monolithic β-glycine spherulite, instead of more commonly observed multiple spherulites, was formed in alginate matrix, thereby resulting in outstanding piezoelectric property, including high piezoelectric constant (7.2 pC/N) and high piezoelectric sensitivity (1.97 mV/kPa). The Gly-Alg-Glycerol film exhibited superior flexibility, enabling complex shape-shifting, e.g. origami pigeon, 40% tensile strain, and repeated bending and folding deformation without fracture. In vitro, the flexible Gly-Alg-Glycerol film sensor could detect subtle pulse signal, sound wave, and recognize shear stress applied from different directions. In addition, we have demonstrated that the Gly-Alg-Glycerol film sensor sealed by polylactic acid and beeswax could serve as an in vivo sensor to monitor physiological pressure signals such as heartbeat, respiration, and muscle movement. Finally, the Gly-Alg-Glycerol film possessed good biocompatibility, supporting the attachment and proliferation of rat mesenchymal stromal cells, and biodegradability, thereby showing great potential as biodegradable piezoelectric biomaterials for biomedical sensing applications.
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危险品化学品经营许可证（带存储）