Polymers
·
2019
·Vol. 11
·期 3
·502
·
IF 3.164
Wenjuan Guo,Tingcheng Xia,Meishan Pei,Yankai Du,Luyan Wang
The main object of this work is to remove Amido black 10B using a new type of bentonite-based adsorbent with cationic groups by the modification of polyallyl amines between the interlayers of bentonite. Fourier transform infrared, X-ray diffraction, thermogravimetric analysis, and scanning electron microscopy were used to characterize the functionalized bentonite. A series of batch adsorption experiments were performed. The maximum adsorption amount was 144.08 mg g−1when the pH was 2 and the contact time was 120 min. In addition, the equilibrium isotherm data were analyzed using Langmuir and Freundlich isotherm models, while only the Langmuir model could provide a high correlation. Therefore, this study provided a new functionalized bentonite as a low-cost adsorbent for dye removal from water.
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DOI
高影响因子
Journal of Physical Chemistry C
·
2023
·
IF 3.7
Siqi Zhu,Xuefang Lu,Lu Cheng,Lemin Jia,Wei Zheng
Cubic boride crystals with pure boron isotopes have attracted great attention in recent years. Here, high-quality cubic boron phosphide single crystals with isotopic 10B and a maximum width reaching 1.5 mm are grown via the high-temperature molten salt method. An interesting phenomenon that there are many discrete sharp lines in the low-temperature (4–80 K) photoluminescence spectra is observed. Besides, as temperature increases, the luminescence intensity of these sharp lines shows a nonmonotonic decay with two different trends exhibited. Based on analyses, the sharp-line emission originates from phonon-assisted donor–acceptor pair radiative recombination. The nonmonotonic decay is affected by the number of assisting phonons and the degree of thermal ionization under the effect of temperature, and the different decay trends are attributed to the effect of thermal ionization dependent on the distance between the donor and acceptor. Results obtained in this research are expected to enrich the knowledge concerning cubic boride crystals in the aspect of physical properties.
研究领域:
材料科学
·
固体物理
·
光学材料
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高影响因子
Nano Today
·
2025
·
IF 10.9
Linwen Lv,Qiuyang Liu,Wenxi Su,Haojun Liang,Xin Pan,Junhui Zhang,Ranran Chen,Ziteng Chen,Zhijie Wang,Ruyu Yan,Mingxin Yang,Yanan Chang,Juan Li,Gengmei Xing,Kui Chen
Boron neutron capture therapy (BNCT) is a promising binary radiotherapy that uses the isotope 10 B and thermal neutron irradiation to induce lethal nuclear reactions in tumor cells. However, the effectiveness of BNCT often relies on the precise match between 10 B and thermal neutrons. In this study, we developed a boron delivery system, integrating boron nitride ( 10 BN) nanoparticles with microneedle (MN) patches (referred to as BN-MN). At equivalent dosages, BN-MN was able to maintain an intratumoral boron concentration above 20 ppm for over two hours, effectively aligning with the neutron irradiation time window. BN-MN also demonstrated efficient penetration and uniform distribution throughout the entire tumor tissue, with a tumor-to-normal tissue ratio (T/N) of 42 and a tumor-to-blood ratio (T/B) of 150, significantly superior to clinical boron drugs. More importantly, BN-MN efficiently delivered boron into tumor tissues at a precise cellular resolution, achieving an intracellular boron concentration 6.8 times higher than that obtained by BPA-loaded microneedles (BPA-MN). In vivo experiments demonstrated that the BN-MN system effectively inhibited tumor growth under neutron irradiation, with minimal systemic side effects. In summary, BN-MN perfectly matched neutron irradiation in terms of sufficient concentration, optimal retention time, and uniform spatial distribution, thereby enhancing the therapeutic efficacy and safety of BNCT.
研究领域:
医学
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放射治疗学
·
纳米医学
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DOI
高影响因子
Journal of Nano Research
·
2017
·
IF 0.511
Wan Xin Jia,Dong Tao Lu,Shao Min Shuang,Jun Yang,Chuan Dong
Magnetic chitosan nanoparticles (Fe3O4-CS MNPs) were synthesized by an improved one-pot hydrothermal method and applied for azo dye amido black 10B adsorption. The Fe3O4-CS MNPs were characterized by SEM, TEM, DLS, XRD, FTIR, TGA and VSM. The adsorptive behavior of amido black 10B on Fe3O4-CS MNPs was investigated using the UV-vis specteophotometric technique and the affecting parameters including solution pH, contact time, amido black 10B concentration and Fe3O4-CS MNPs amount were examined. The adsorption process followed the pseudo-second-order kinetic model. The adsorption equilibrium data fitted well with the Freundlich isotherm model with the saturated adsorption capacity of 124.8 mg/g at pH=2.0. The desorption experiment could be carried out using NaOH with the recovery of 91.78%. After five cycles, adsorption efficiency still reached 83.24%. The results showed that Fe3O4-CS MNPs possessed a simple synthesis route and excellent reusability, which have potential application in the adsorption of azo dye in environmental effluents.
研究领域:
材料科学
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环境科学
·
化学工程
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DOI
高影响因子
FISH PHYSIOLOGY AND BIOCHEMISTRY
·
2026
·Vol. 52
·期 1
·11
·
IF 2.5
Yu Jinzhi,Wang Naixuan,Liu Lijun,Zhou Hong,Zhang Anying,Wang Xinyan
S100A10 protein, a member of S100 protein family, has been extensively studied in mammalian models. In fish species, evolution of S100 proteins including S100A10 has been clarified, revealing that two paralogous genes, S100A10a and S100A10b , arose in teleosts through the fish-specific whole-genome duplication event. However, the functional roles of fish S100A10 genes remain largely uncharacterized. In the present study, we identified two S100A10 homologs in grass carp, designated gcS100A10a and gcS100A10b, and demonstrated that their mRNA is highly expressed in grass carp skin and strongly upregulated after skin trauma by real-time quantitative PCR. Using the fish epithelial cell line, Epithelioma papulosum cyprini (EPC) cells, as a model, we showed that overexpression of gcS100A10a or gcS100A10b enhances cell viability, increases expression of proliferating cell nuclear antigen (PCNA), and promotes DNA synthesis, thereby demonstrating their capacity to stimulate cell proliferation. Flow cytometric analysis further uncovered that both proteins accelerate EPC cell cycle progression by promoting transition into the S and G2/M phases. Additionally, gcS100A10a and gcS100A10b significantly elevate EPC cell migration and this elevation is attenuated by a broad-spectrum matrix metalloproteinase (MMP) inhibitor, GM6001, suggesting involvement of MMP activity in this process. This suggestion is strongly supported by findings that overexpression of gcS100A10a or gcS100A10b increases extracellular MMP activity and decreases intracellular MMP accumulation although MMP-2 / MMP-9 mRNA levels remain unchanged. Collectively, these results demonstrate the positive regulation of gcS100A10a and gcS100A10b on fish epithelial cell proliferation and migration, together with their high and injury-inducible expression in grass carp skin, indicating their possible involvement in fish skin wound healing.
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产品关联
DOI
PubMed
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2021
·Vol. 31
·期 24
·2100969
·
IF 18.808
Juan Li,Jianglong Kong,Sihan Ma,Jiacheng Li,Meiru Mao,Kui Chen,Ziteng Chen,Jiaxin Zhang,Yanan Chang,Hui Yuan,Tong Liu,Zizhu Zhang,Gengmei Xing
Novel boron-containing carbon dots (BCDs) are designed and prepared for boron neutron capture therapy (BNCT) with superior water solubility and excellent optical property for tracking 10 B in vitro and in vivo. Encapsulation of BCDs using exosomes (Exos) from macrophages yields BCD–Exos of ≈100 nm. Fluorescent imaging shows that the BCD–Exos are internalized and distributed around the nuclei of U-87-MG glioma cells. BCD–Exos are also verified to cross the blood–brain barrier and significant accumulation in tumor tissue of the orthotopic U-87-MG glioma tumor-bearing mice model 4 h after administration. Using inductively coupled plasma mass spectrometry (ICP-MS), it is detected that 10 B in tumor tissue is 107.07 ± 1.58 ppm, and T/N ratios are enhanced from 2.03 ± 0.08 of boron phenylalanine (BPA) to 5.28 ± 0.29 of the BCD–Exos. In BNCT, the neutron radiation dose is 8.40 ± 0.12 Gy when a 500 mg kg −1 10 B dosage is given. Finally, there is a prominent BNCT effect of the BCD–Exos-treated brain glioma in the mice model, and the survival ratio is 100% at the end of the experiment. The excellent curative effect of BNCT using BCD–Exos to brain glioma is achieved through adjusted biodistribution of boron in the cancer cell, enhanced T/N ratios, and the precise match between boron and neutron exposure in the site of the tumor in vivo with fluorescence imaging of BCD–Exos.
研究领域:
肿瘤学
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放射治疗
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纳米医学
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神经科学
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产品关联
DOI
高影响因子
RSC Advances
·
2019
·Vol. 9
·期 70
·40845-40854
·
IF 3.049
Saira Shams,Waqas Ahmad,Amjad Hussain Memon,Yun Wei,Qipeng Yuan,Hao Liang
Herein, we report an effectual method for designing a novel form of nanozyme laccase mimic namely Cu/H3BTC, using copper ions and 1,3,5-benzene tricarboxylic acid (1,3,5-H3BTC). This Cu-based metal–organic framework (MOF) was synthesized through a simple procedure of mixing of two usual reagents at room temperature. Amido Black 10B (AB-10B) was chosen as a model dye for degradation consequences. Results showed that Cu/H3BTC MOF revealed significantly higher catalytic efficacy under certain conditions like high pH, extreme temperature and high salt conditions and it has long-term storage stability, which can lead to a significant decline in catalytic activity of laccase. In addition, the degradation of AB-10B was up to 60% after ten cycles, showing good recyclability of Cu/H3BTC MOF. The UV-visible spectral changes clearly showed that Cu/H3BTC MOF is an effective laccase mimic for the degradation of azo dye AB-10B, which was degraded more easily within the time duration of 60 min. The Cu/H3BTC MOF also possessed fundamental activities like laccase with regard to oxidation of the phenolic compounds. Moreover, a technique for the quantitative detection of epinephrine by Cu/H3BTC MOF was established. These findings help to understand the laccase-like reactivity and provide a basis for the future design and application of metal-based catalysts.
研究领域:
催化
·
环境科学
·
材料科学
·
分析化学
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产品关联
DOI
PubMed
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2025
·
IF 19
Shuang Zhao,Xuesong Wang,Ruijia Deng,Xiaoqi Tang,Zuowei Xie,Ping Huang,Xianlan Wu,Jie Luo,Yu Tang,Jing Sheng,Sha Yang,Ming Chen,Kai Chang
Synthetic catalytic DNAzyme circuits have gained great attention as versatile theranostic toolboxes, but their accuracy and efficiency is restricted by uncontrolled signal leakage and inefficient circuitry activation. Here, a trinity DNAzyme circuit (TriDC) is constructed using a unique logic gate bioswitchable DNA tetrahedral walker@MnO 2 nanosheets structure. The AND logic gate bioswitchable DNA tetrahedral walker, composed of dual allosteric DNAzyme (termed “commander” and “soldier”) and tetrahedral scaffold, is used to execute imaging-guided gene therapy by avoiding undesired signal leakage and cascade “walking” in a confined space. Glutathione-mediated reduction of MnO 2 nanosheets provides secondary confinement to stack the DNA tetrahedral walker in situ, offering abundant Mn 2+ as a cofactor to achieve self-sufficiency of DNAzyme circuits and induce chemo-dynamic therapy. The structure increases local reaction concentrations by ≈100-fold according to the collision frequency model, enabling the AND logic detection of microRNA-10b and microRNA-155 at a limit of detection of 98.97 p m , thereby facilitating the precise imaging of breast cancer cells. The combined gene/chemo-dynamic therapy achieves 66.2% tumor growth inhibition efficiency. The TriDC offers novel insights into tumor theranostics and also presents a paradigm for the in situ implementation of higher-order DNAzyme circuits.
研究领域:
纳米技术
·
生物医学工程
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诊疗学
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癌症研究
·
分子生物学
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生物化学
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DOI
高影响因子
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