EUROPEAN FOOD RESEARCH AND TECHNOLOGY
·
2016
·Vol. 242
·期 7
·1177-1185
·
IF 1.433
Ma Fumin,Dang Yali,Xu Shiying
In this study, water-extractable arabinoxylan, WEAX, of wheat was isolated and mixed with gluten to observe small and large strain behavior and microscopic structure of the mixtures. The results showed that WEAX improves the viscoelasticity of gluten and makes the microscopic structure of gluten less compact. Free sulfhydryl, fluorescence anisotropy and CP/MAS 13 C NMR measurements were used to gain a better understanding of the interactions between WEAX and gluten proteins of wheat. It was demonstrated that when gluten was mixed with WEAX, the free –SH of gluten proteins cross-linked to each other or to WEAX. The cross-linking happened mainly to LMW-GS. It was shown from the fluorescence anisotropy that the conformation of glutenin was more greatly influenced by WEAX than gliadin because of the difference in their molecular conformation. In addition, it was found in this study that tyrosine groups of glutenin also played an important role in the interactions between WEAX and gluten.
研究领域:
食品科学
·
分子生物学
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DOI
高影响因子
FOOD RESEARCH INTERNATIONAL
·
2023
·
IF 8.1
Wenjiang Dong,Qidi Hong,Jinhuan Cheng,Hongyan He,Yanan Li,Rongsuo Hu,Yuzhou Long
Green coffee oil (GCO) extracted from green coffee beans, is known for its antioxidant and anticancer properties, and has been increasingly utilised in cosmetic and other consumer products. However, lipid oxidation of GCO fatty acid components during storage may be harmful to human health, and there remains a need to understand the evolution of GCO chemical component oxidation. In this study, proton nuclear magnetic resonance ( 1 H and 13 C NMR) spectroscopy was used to investigate the oxidation status of solvent-extracted and cold-pressed GCO under accelerated storage conditions. Results show that the signal intensity of oxidation products gradually increased with increasing oxidation time, while unsaturated fatty acid signals gradually weakened. Five different types of GCO extracts were clustered according to their properties, except for minor overlapping in the two-dimensional plane of the principal component analysis. Partial least squares-least analysis results demonstrate that oxidation products ( δ = 7.8–10.3 ppm), unsaturated fatty acids ( δ = 5.28–5.42 ppm), and linoleic acid ( δ = 2.70–2.85 ppm) in 1 H NMR can be used as characteristic indicators of GCO oxidation levels. Furthermore, the kinetics curves of unsaturated fatty acids, linoleic, and linolenic acyl groups all fit an exponential equation with high coefficients of GCO for 36 days under accelerated storage conditions. Our results show that the current NMR system is a fast, easy-operated and convenient tool for the oxidation process monitoring and quality control of GCO.
研究领域:
食品科学
·
分析化学
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产品关联
DOI
PubMed
高影响因子
AAPS PHARMSCITECH
·
2021
·Vol. 22
·期 5
·1-14
·
IF 3.246
Luo Zheng,Liu Chao,Quan Peng,Zhang Yimeng,Fang Liang
Chemical penetration enhancers (CPEs) are commonly added into transdermal patches to impart improved skin permeation of drug. However, significant unexplained variability in drug release kinetics in transdermal patches is possible as a result of the addition of CPEs; investigations into the underlying mechanisms are still limited. In the present study, a diverse set of CPEs was employed to draw broad conclusions. Solubility parameters of CPEs and acrylate pressure-sensitive adhesive were calculated by molecular dynamics simulation and Fedors group contribution method to evaluate drug-adhesive miscibility. CPE-adhesive interaction was characterized by FT-IR study, 13 C NMR spectroscopy, and molecular docking simulation. Results showed that release enhancement ratio ( ER R ) of CPEs for zolmitriptan was rank ordered as isopropyl myristate > azone > Plurol Oleique ® CC497 > Span ® 80 > N -methylpyrrolidone > Transcutol ® P. It was found that solubility parameter difference (Δ δ ) between CPE and adhesive was negatively related with ER R . It was proved that hydrogen bonding between CPE and adhesive would increase drug release rate, but only if the CPE showed good miscibility with adhesive. CPE like isopropyl myristate, which had good miscibility with adhesive, could decrease drug-adhesive interaction leading to the release of drug from adhesive.
研究领域:
药剂学
·
药学化学
·
生物物理学
·
材料科学
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DOI
高影响因子
International Journal of Greenhouse Gas Control
·
2014
·
IF 3.821
Chao Guo,Shaoyun Chen,Yongchun Zhang
Quantitative 13 C nuclear magnetic resonance (NMR) spectroscopy was used to study carbon dioxide (CO 2 ) absorption and desorption, at 313 and 393 K, respectively, from 30 wt% aqueous 2-(2-aminoethylamine)ethanol (AEEA), 30 wt% 2-amino-2-methyl-1-propanol (AMP) and 20 wt% AEEA + 10 wt% AMP solutions. The 13 C NMR results indicate that the main AEEA species are free amine, protonated amine, primary carbamate and secondary carbamate, and the main AMP species are free amine and protonated amine. There is no evident indication that dicarbamate species of AEEA and carbamate of AMP are formed. When AEEA absorbs CO 2 , the formation of AEEA carbamate on primary amine is comparatively faster than that on secondary amine. During the CO 2 desorption process, the AEEA carbamate on secondary amine is produced by an endothermic reaction, which reduces the overall efficiency of desorption. Six cycles of absorption–desorption tests are performed to measure the feasibility of regenerated amine solutions for reuse and the absorption amount of them remains essentially constant during the second to the sixth absorption–desorption experiments. Compared with pure AEEA solution, the recyclability of blended amines, AEEA + AMP, improves while the mol CO 2 /mol amine (CO 2 loading) of the blended amines decreases.
研究领域:
化学工程
·
环境化学
·
碳捕集与封存（CCS）
·
物理化学
·
核磁共振（NMR）波谱学
✓ 已验证
DOI
高影响因子
Polymer Chemistry
·
2022
·Vol. 13
·期 27
·4054-4063
·
IF 5.364
Tianxiao Chang,Hongyi Qi,Chenxi Liang,Yanbin Huang,Wantai Yang
Benzothiophene is an under-explored monomer for free radical polymerization. Here we report the preparation of poly(benzothiophene-alt-maleic anhydride) (PBTMA) microspheres with high yield by self-stabilized precipitation polymerization. The chemical structure of the PBTMA copolymer was characterized by 1H-NMR, 13C-NMR, FT-IR and MALDI-TOF MS analyses. The effects of various reaction parameters, including the reaction medium, the monomer concentration, the initiator concentration and the reaction time, on the morphology, particle size and molecular weight (Mn) of the resultant PBTMA microspheres were investigated systematically. The experimental results demonstrated that the PBTMA copolymer was an alternating copolymer, whose composition was independent of the monomer composition. Uniform PBTMA microspheres with the diameter in the range of 400 nm to 3000 nm and Mn up to 12 000 g mol−1 were easily prepared. PBTMA had good solubility in common polar organic solvents and possessed much higher thermal stability than other maleic anhydride copolymers. PBTMA also showed interesting fluorescence properties both in the solid state and in solution. This research has laid the foundation for the further development of PBTMA copolymers as a new material.
研究领域:
高分子科学
·
材料科学
·
化学工程
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产品关联
DOI
高影响因子
POLYMER BULLETIN
·
2022
·Vol. 80
·期 1
·725-738
·
IF 2.843
Zhang Huadong,Yan Zhongyi,Yang Zhizhou,Mu Qiuhong,Peng Dan,Zhao Hui
Two low melting point phthalonitrile monomers (EPN and EEPN) containing flexible glycidyl groups were synthesized using hydroxyl-containing phthalonitrile and epichlorohydrin as raw materials. The structures of the synthesized monomers were characterized by Fourier transform infrared (FT-IR), nuclear magnetic resonance ( 1 H-NMR and 13 C-NMR) spectra and elemental analysis. Then each of them was blended with 4-(4-aminophenoxy)-phthalonitrile (APPN) and cured to obtain two kinds of amine-catalytic phthalonitrile-based crosslinked polymers. DSC results showed that two blending systems underwent a two-stage polymerization process with the increase of curing temperature. Rheological measurements exhibited that the introduction of glycidyl groups to phthalonitrile resin could greatly improve its processability. Moreover, after thermal cured at 300 ℃, the resulting phthalonitrile resins exhibited excellent mechanical performance, thermal and thermo-oxidative stability.
研究领域:
材料科学
·
高分子化学
·
热能工程
✓ 已验证
产品关联
DOI
高影响因子
CARBOHYDRATE POLYMERS
·
2022
·
IF 10.723
Lianxiong Guan,Zhi Zeng,Wei Liu,Tengfei Wang,Shiyao Tian,Sheng Hu,Dating Tian
Amphiphilic AIE nanoparticles (CD-TPE) were obtained by linking γ-cyclodextrin (γ-CD) and 1, 2-diphenyl-1, 2-( p -hydroxyphenyl)-ethylene (OH-TPE-OH) by an esterification reaction using hexamethylene diisocyanate (HMDI) in a one-step process. The CD-TPE was characterized by FTIR, 13 C NMR, DSC , XRD, particle size analysis , TEM, and FL. The obtained CD-TPE had good water dispersibility and could self-assemble into AIE nanoparticles. The large cavity of CD-TPE provided convenient conditions for the loading of doxorubicin (DOX) and slow-release DOX with the loading and release rates of 67.4 % and 71.3 % (pH = 5.4), respectively. The DOX release kinetic model was suitable for the Bhaskar model. Cytotoxicity analysis and cell imaging of CD-TPE were performed, showing that CD-TPE has good biocompatibility and excellent cell imaging performance. Moreover, both in vitro and in vivo antitumor experiments showed that CD-TPE has promising applications in drug delivery.
研究领域:
生物医学工程
·
纳米技术
·
药学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
GREEN CHEMISTRY
·
2015
·Vol. 18
·期 6
·1738-1750
·
IF 8.02
Jiliang Ma,Linxin Zhong,Xinwen Peng,Runcang Sun
A simple and effective synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones and their derivatives from aldehydes, β-dicarbonyl compounds and urea or thiourea using D-xylonic acid both as a green solvent and an effective catalyst is described. Taking the environment and economy into account, the work presented here has the merits of environmental friendliness, easy operation, simple work-up, excellent yields and the avoidance of organic solvents and inexpensive catalysts. In addition, the good properties of D-xylonic acid have also been validated by the synthesis of 5-phenyl-1(4-methoxyphenyl)-3[(4-methoxyphenyl)-amino]-1H-pyrrol-2(5H)-one and 12-phenyl-9,9-dimethyl-8,9,10,12-tetrahydrobenzo[a]xanthen-11-one. The synthesized compounds were characterized by FT-IR, 1H NMR, 13C NMR and melting point.
研究领域:
有机化学
·
绿色化学
·
催化
·
合成
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2022
·
IF 8.025
Peng Zhou,Xiangzhou Li,Zhi Jiang,Jun Zhou,Guang He,Limin Qu
In this paper, a kind of superabsorbent resin (SAR) with superior quality for hygiene products was developed using Fructus Aurantii Immaturus pectin (FAIP) from Citrus aurantium L.. FAIP-g-AM/AMPS SAR was established by free radical graft co -polymerization with FAIP as skeleton structure, N, N′-Methylene-bis (acrylamide) (MBA) as the cross-linker. Meanwhile, the functional monomers of acrylamide (AM) and 2-acrylamido-2-methylpropane sulfonic acid (AMPS) were introduced. The structure and morphology of FAIP-g-AM/AMPS were characterized by FTIR , 13 C NMR, XRD, SEM and TG-DSC analysis. The results confirmed that the AFIP-g-AM/AMPS SAR was successfully prepared, which exhibited a three-dimensional (3D) network structure and an excellent thermal stability . The absorption and retention capacity of FAIP-g-AM/AMPS was comparable to or even better than commercial diapers and sanitary napkins. Significantly, FAIP-g-AM/AMPS itself exhibited excellent antibacterial and safety. FAIP-g-AM/AMPS has an inhibition ratio of 97.1 % for Escherichia coli ( E. coli ) and 98.5 % for Staphylococcus aureus ( S. aureus ), and was non-irritating and non-allergic to the skin. In addition, FAIP-g-AM/AMPS presented amazing biodegradability and a weight loss reached 37.1 % after 30 days by soil burial test. The research provides a safe and high-performance SAR, which expected to be used in hygiene products such as baby diapers, adult incontinence pads and sanitary napkins.
研究领域:
材料科学
·
高分子化学
·
生物技术
·
环境科学
·
卫生用品
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）