Analytical Methods
·
2017
·Vol. 9
·期 38
·5580-5585
·
IF 1.9
Xialin Chen,Jin Qi,Boyang Yu
Compound Danshen Dripping Pills (CDDPs) are a Chinese herbal medicinal preparation composed of Salviae miltiorrhizae Radix and two other Chinese medicines, Notoginseng Radix and Borneolum. The main components of CDDPs are protocatechuic aldehyde, danshensu, salvianolic acid A, rosmarinic acid, ginsenoside Rg1, ginsenoside Rb1, L-(−)-borneol and isoborneol. The complex composition of CDDPs, which contains phenolic acids, ginseng saponins and borneols, makes quantitative analysis by traditional methods difficult. Therefore, a fast and accurate 1H qNMR method was established that can simultaneously determine the eight main components of CDDPs. The qNMR method was well validated and successfully applied in the determination of ten sample batches. The vector cosine angle method was used for further analysis of the results to evaluate the sample quality. The results indicate that the qNMR method is suitable for the quality control of CDDPs and has potential as an easy alternative for the analysis of other complex Traditional Chinese Medicines (TCMs) that require two or more traditional instruments for comprehensive quantitative analysis.
研究领域:
药学
·
分析化学
·
中药学
✓ 已验证
产品关联
DOI
高影响因子
MATERIALS CHEMISTRY AND PHYSICS
·
2022
·
IF 4.778
Zhijia Zhang,Huifeng Mei,Qiang Wang,Rui Li,Guojun Wang,Hao Wei,Xiao Ouyang
Unlike the organisms in nature, the synthetic materials are difficult to repair the damage via self-regulation. Even the self-healing materials generally require the external stimuli (e.g., temperature, pressure, light, etc ) to repair themselves. In this paper, self-healing polyurethane elastomer was designed and prepared based on 2-ureido-4[1 H ]-pyrimidinone compound by the simple physical blending method. The tensile strength and the elongation at break of the self-healing polyurethane elastomer were 0.65 MPa and 623.1%, respectively. The healing performance was measured by cut-off experiment, showing that the fracture of the self-healing polyurethane elastomer was healed at room temperature without external stimuli and kept excellent mechanic properties. The healing efficiencies of the tensile strength and the elongation at break were achieved to 87.7% (0.57 MPa) and 71.7% (446.7%) after healing at room temperature with 30 h, respectively. When the temperature was up to 80 °C, the healing time curtailed at 1 h. And the tensile strength and the elongation at break were recovered to 0.59 MPa and 532.1%, respectively. These promising results provide a strategy that allows increasing the life cycle of materials, adapting them to a circular economy model, thus reducing the generation of waste.
研究领域:
材料科学
·
高分子化学
✓ 已验证
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2017
·
IF 3.359
Qizhou Dai,Wei Chen,Jinming Luo,Xubiao Luo
In this work, we investigated the abatement of highly concentrated 1H-Benzotriazole (BTA) in aqueous solution by ozonation. Focusing on the COD removal and BTA degradation, the effects of different operational factors were explored, including different initial BTA concentrations (100–1000 mg/L), ozone dosages (16–48 mg/min) and initial pH values (3–11). It was found that the degradation of BTA was obviously affected by the initial concentration of BTA, pH value and O 3 dosage. And the optimized pH value was observed at 11. The increasing of ozone dosage and the pH value would accelerate the degradation efficiency of BTA and COD removal, while the increasing of initial BTA concentration would hamper this process. Based on the effects of ozone dosage, initial BTA concentration and initial pH value, a kinetic model was established with the function of C = C 0 exp(−8.68Q O3 2.4997 C 0 −2.1262 [OH − ] 0.0444 t).
研究领域:
环境科学
·
水处理
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
·
2022
·
IF 6.437
Jianwei Zhang,Ling Chen,Liangyou Zhao,Guorui Jin,Weidong He
Nitrogen heterocycles as Nitrogen-rich energetic material has been widely popularized due to their desirable properties like low sensitivities, excellent stability, and lower environmental impact, less erosive and less toxic combustion gases , especially in gun propellant application areas. The focus of this study is on investigating interaction mechanism of 1 H-tetrazole (1 H-TZ) and nitrocellulose (NC) by kinetics methods and TG-DSC-FTIR analysis. The mixture (NC-TZ) between 1 H-TZ and NC was prepared by means of physical blending. DSC experiments indicated that the open and closed environment can generate different and important influence on the chemical reaction between 1 H-TZ and NC. Combined with the change of activation energy , it illustrated that the gas 2 H-tetrazole, the isomer of 1 H-TZ, had a significant influence on the thermal decomposition of NC. In comparison with kinetic models of NC and NC-TZ, it can be found that the addition of 1 H-TZ mainly affected the contribution factor and m value in the first stage. The value of m decreased from 1.00 to 0.15, meanwhile, the contribution factor was decreased from 0.50 to 0.12. It showed that NO 2 , the initial decomposition product of NC, had taken part in the thermal decomposition process of 1 H-TZ. TG-DSC-FTIR experiments indicated that there was a chemical reaction between 2 H-tetrazole and the initial decomposition product of NC, NO 2 , to form CO, N 2 O and HN 3 .
研究领域:
化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
MOLECULES
·
2024
·Vol. 29
·期 14
·3396
·
IF 4.2
Zhengyang Wang,Shuting Wang,Yuexing Zhang,Mingliang Ma
A series of fluorescent molecules with 1,1-dimethylnaphthalene-2(1H)-one as the core were synthesized to overcome aggregation quenching and emit bright green fluorescence. The low molecular weight of these molecules led to them to smoothly pass through the cell membrane and penetrate deep into the nucleus to emit the corresponding fluorescence. Among them, NC-4-Br and NC-5-3O have good optical and in vitro properties and showed potential for use as fluorescent probes.
研究领域:
生物化学
·
分子生物学
·
医学成像
✓ 已验证
DOI
PubMed
高影响因子
RSC Advances
·
2017
·Vol. 7
·期 82
·52321-52326
·
IF 3.108
Zhenzhen Wu,Juan Li,Xian-Ming Zhang
In this study, we introduced 1H-1,2,4-triazole into the ordered nanochannels of propyl amino functioned MCM-41 and then investigated the hybrids' proton conducting performance. A high proton conductivity of 8.34 × 10−3 S cm−1 has been obtained at 120 °C, with 5 mol% mole ratio of dangling propyl amino and fully loaded 1H-1,2,4-triazole in the silica. The activation energy is 0.55 eV and 1.303 eV in the temperature range below and above 80 °C respectively, indicating that the charge transfer mechanism of the material involved both vehicle and Grotthuss process. The above results showed that loading of 1-H-1,2,4-triazole molecules into silica's ordered mesopores is a good strategy for excellent proton conductivity under intermediate temperature.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2024
·Vol. 48
·期 38
·16776-16794
·
IF 2.7
Jianwei Zhang,Chengming Bian,Ling Chen,Weidong He
Recently, we investigated the interaction mechanism of 1H-tetrazole (1H-TZ) and nitrocellulose (NC). Next, we tried to introduce an amino group at the C and N atoms of 1H-tetrazole, so as to explore the influence of amino group modification on the pyrolysis process of NC. The focus of this study was on investigating the interaction mechanism of aminotetrazole (5-ATZ or DATZ) and NC through kinetics methods and TG-DSC-FTIR analysis. The quenching and reheating experiments revealed that the imino form of 5-ATZ or DATZ played an important role in this process. The addition of aminotetrazole (5-ATZ and DATZ) mainly affected the autocatalytic reaction at the initial stage of the pyrolysis process of NC. TG-DSC-FTIR experiments revealed that there was a chemical reaction between NO2 and decomposition products of 5-ATZ or DATZ. In this reaction, R–NCNH or NC–NH–R (R = H and NH2) reacted with NO2 to form N2O and CO2.
研究领域:
化学动力学
·
材料科学
·
热分析
✓ 已验证
产品关联
DOI
高影响因子
ACS Sustainable Chemistry & Engineering
·
2018
·
IF 6.14
Guiling Shi,Kaihong Chen,Yongtao Wang,Haoran Li,Congmin Wang
Ionic liquids can be designed by varying a great deal of anions and cations offering efficient CO2 capture or CO2 utilization. Generally, the anion played a key role, but the cation did not have a significant impact. Here, a strategy for rational design of functionalized ionic liquids for efficient synthesis of quinazoline-2,4(1H,3H)-diones from CO2 has been developed through tuning the cations of aprotic ionic liquids. The basicity of cation affects its catalytic activity dramatically and the hydrogen bond from cation can promote this reaction. Then, hydroxyl functionalized ionic liquid [Ch][Im] was designed, which exhibited the best catalytic activity in this reaction. Through the combination of quantum-chemical calculations, NMR spectroscopic investigations, and controlled experiments, the results indicate that in situ generated [Ch][Im]-CO2 complex is the real catalyst. Furthermore, aprotic IL [Ch][Im] exhibits good generality and reuseability. Remarkably, quinazoline-2,4(1H,3H)-dione can also be obtained under simulated flue gas system on a gram scale with excellent yield using [Ch][Im] as catalyst. As we know, this is the first time that obtains quinazoline-2,4(1H,3H)-dione in excellent yield under flue gas condition.
研究领域:
化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF BIOTECHNOLOGY
·
2013
·
IF 3.183
Zong-Bo Xie,Na Wang,Wan-Xia Wu,Zhang-Gao Le,Xiao-Qi Yu
A simple, mild, one-pot tandem method catalyzed by trypsin was developed for the synthesis of 3,4-dihydropyrimidin-2(1 H )-ones by the Biginelli reaction of urea, β-dicarbonyl compounds, and in situ-formed acetaldehyde. Trypsin was found to display dual promiscuous functions to catalyze transesterification and the Biginelli reaction in sequence.
研究领域:
生物化学
·
有机合成
✓ 已验证
DOI
PubMed
高影响因子
International Journal of Electrochemical Science
·
2023
·
IF 1.5
Chuan Lai,Hongxia Yang,Xiaogang Guo,Xiulan Su,Lvshan Zhou,Lei Zhang,Bin Xie
The new organic corrosion inhibitor of 2-( p -bromobenzylthio)-1 H -benzimidazole (Br-BBD) was synthesized in this work. After prepared, the adsorption and corrosion inhibition performance of Br-BBD for Q235 steel in HCl solution were studied using EIS, SEM, polarization measurement and WLM (weight loss measurement). The results exhibit that Br-BBD acts as an excellent corrosion inhibitor for Q235 steel in HCl solution, and the inhibition efficiency can reach up to 98.07% when the Br-BBD concentration is 50 mg L -1 in 1.0 M HCl at 25°C. In addition, the adsorption of the mixed-type inhibitor of Br-BBD on Q235 steel surface obey Langmuir adsorption isotherm, which is governed by spontaneous chemisorption mechanism.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
TETRAHEDRON LETTERS
·
2018
·Vol. 60
·期 5
·402-406
·
IF 2.125
Xingquan Xiong,Chao Yi,Xu Liao,Shilin Lai
A series of 5-substituted-1 H -tetrazoles have been efficiently synthesized in moderate to excellent yields (68–90%) under mild reaction conditions by combining aryl aldehydes, hydroxylamine hydrochloride with sodium azide in the presence of catalytic amount of Cu(OAc) 2 in deep eutectic solvent (DES). The new synthetic method has many advantages, such as high conversion, green reaction medium, easy work-up, low cost, and environment friendly.
研究领域:
有机化学
·
药物化学
·
绿色化学
·
合成方法学
✓ 已验证
DOI
高影响因子
LETTERS IN ORGANIC CHEMISTRY
·
2024
·Vol. 22
·期 1
·56-60
·
IF 0.7
Xin-Yu Lin,Guo-Jun Chen,Su-Zhe Wu,Ke-Xuan Xu,Xiao-Tian Zhang,Qi Feng
4-Hydroxyquinoline-2(1H)-ones exhibit multiple biological activities, and studying their synthetic methods is of great significance. In the presence of tetramethylguanidine and silver nitrate, 4-hydroxyquinoline-2(1H)-ones were efficiently synthesized from 2-ethynylanilines and carbon dioxide under atmospheric pressure. The reaction conditions, such as types of silver catalysts and reaction solvents, were optimized, and the applicability of the substrate was preliminarily investigated. This method provides an alternative pathway for the synthesis of 4-hydroxyquinoline-2(1H)-ones and the conversion and utilization of carbon dioxide.
研究领域:
有机化学
·
药物化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）