Chemical Engineering and Processing-Process Intensification
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2025
·
IF 3.9
Fan Feng,Xuyu Yang,Ruiqiang Yan,Shengwei Xiao,Li Chen
Herein, the flash nanoprecipitation (FNP) technique, which enables the highly efficient mixing of aqueous barium (Ba 2+ ) and sulfate (SO 4 2− ) in a multi-inlet vortex mixer, is adopted for the scalable fabrication of barium sulfate nanoparticles in a well-controlled manner. Barium sulfate nanoparticles with an average size of 40 nm and a narrow size distribution (polydispersity = 0.18) are successfully produced at a yield of 0.7 kg/h. The size of the fabricated nanoparticles decreases and uniformity enhances with an increase in the volumetric flow rate, feeding concentration, and initial molar ratio between Ba 2+ and SO 4 2− . Moreover, mechanisms underlying this trend are investigated; FNP's sub-millisecond mixing at high volumetric flow rates, combined with a high nucleation-to-growth rate ratio under elevated supersaturation, and the stabilizing effect of excess Ba 2+ , are crucial for producing high-quality BaSO 4 nanoparticles. Our results demonstrate the FNP technique to be promising for the industrial production of inorganic nanoparticles.
研究领域:
材料科学
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化学工程
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DOI
高影响因子
Applied Materials Today
·
2026
·
IF 7
Man Li,Xuelong Wang,Min Liang,Bingjie Fu,Jieting Chang,Xingpu Liu,Huidi Meng,Hailin Zhang,Changyou Gao
Composite xerogels composed of chitosan and BaSO 4 particles. • Optimal formulation of CS/BaSO 4 xerogels for multimodal imaging. • Hydrated xerogels with appropriate modulus and tissue compatibility. • Resistance of displacement post implantation in vivo . Tissue markers can effectively indicate diseased sites within the body. However, conventional metal-based markers are severely limited by imaging artifacts and high migration risks resulting from mechanical mismatch with soft tissues. Herein, we developed a composite xerogel system composed of chitosan and BaSO 4 particles. Through comprehensive screening, 20–40 wt% BaSO 4 was established as the optimal functional window, within which 40BS-C (a composite xerogel containing 40 wt% BaSO 4 and 60 wt% chitosan) was identified as the optimal formulation for balancing multimodal micro-CT/ultrasound (US)/magnetic resonance imaging (MRI) and mechanical compliance. Upon hydration equilibrium, the compressive modulus of approximately 10 MPa was significantly lower than that of metallic or other rigid materials. Favorable imaging capabilities were shown in both micro-CT and US in vitro . Furthermore, volume swelling and the formation of a moderately thick fibrous capsule provided effective physical anchoring, resulting in significantly lower relative displacement of the markers (4.4–4.6 mm) compared to the metallic counterparts (6.9 mm). A 6-month in vivo animal study confirmed that the markers exhibited favorable multimodal imaging stability (with a micro-CT signal-to-background ratio of 5.43 for the optimal 40BS-C, and an overall US dimensional deviation < 5%) and biocompatibility compared with clinical titanium markers. In summary, this optimized multimodal and anti-migratory marker system provides a reliable strategy for precise lesion localization, demonstrating promising potential for clinical translation. Download: Download high-res image (171KB) Download: Download full-size image
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高影响因子
Journal of Building Engineering
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2025
·
IF 7.4
Linhan Lei,Guokun Yang,Tianle Liu,Bo Qu,Gang Lei,Chuanlin Que,Shaojun Zheng
Microencapsulated phase change materials (MPCMs) are increasingly utilized in energy-efficient building systems, primarily aimed at improving indoor thermal comfort while also reducing overall energy demands. To further extend the range of MPCM applications, recent research efforts have been directed towards the development of MPCMs with enhanced multifunctional capabilities that go beyond traditional thermal energy storage. In this study, a novel multifunctional MPCM, termed Oc/Ei@BaSO 4 , was synthesized using a self-assembly technique. The core consists of a 7:3 blend of octadecane and eicosane, encapsulated within a barium sulfate shell. The high atomic number of Ba provides Oc/Ei@BaSO 4 with enhanced ionizing radiation shielding capabilities. The binary core composition provides dual phase change temperatures of 9.0 °C and 27.6 °C, making it suitable for thermal storage across multiple seasons. After 100 thermal cycles, the latent heat of Oc/Ei@BaSO 4 decreased by only 1.59 J/g, meeting the requirements for good thermal stability in building wall applications. Additionally, cement blocks incorporating various mass fractions of Oc/Ei@BaSO 4 (CPM) were prepared, and their ionizing radiation shielding performance was characterized through both experimental measurements and simulations. The results indicate that the inclusion of Oc/Ei@BaSO 4 significantly improved the shielding capacity of CPM across different X-ray intensities, with the linear attenuation coefficient of CPM 8 % increasing by 27.62 % compared to the control group. The relationship between Oc/Ei@BaSO 4 content and the attenuation coefficient of CPM was further predicted using the XCOM code, showing good predictive accuracy, especially at lower radiation intensities, with deviations from experimental values of around 20 %. The development of this multifunctional MPCM extends the applicability of MPCMs, offering potential for radiation shielding in medical facilities, nuclear power plants, and space radiation protection, providing a promising solution for these specialized areas within the construction industry.
研究领域:
材料科学
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建筑工程
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能量储存
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辐射防护
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核工程
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DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2024
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IF 8.1
Zhengting Yu,Fuchao Yang,Pengcheng Tang,Zhiguang Guo
Pollution from oily waste water is a serious environmental problem worldwide, causing serious damage to the environment and human health. At the same time, emulsifiers also cause great difficulties in wastewater treatment. Although efforts have been made to develop many high performance emulsion separation membranes, it is difficult to have the ability to resist crude oil pollution in practical applications. The construction of superoleophobic micro/nano-scale lamellar structured membranes with the potential to efficiently separate oil/water emulsions was inspired by the oil-resistant properties of fish scales and the unique adhesion of mussels. Tin dioxide, polydopamine and hydrophilic barium sulphate have been modified on the surface of stainless steel mesh by in-situ hydrothermal and dip coating. The superhydrophilic stainless steel mesh was successfully prepared by using the adhesion of polydopamine. Using the excellent underwater hydration ability of tin dioxide and the hydroxyl group-rich hydrophilic barium sulfate, the modified membrane showed excellent resistance to crude oil pollution. The superhydrophilic membrane can continuously separate different types of oil-in-water emulsions with high separation efficiency (99.9 %) and excellent separation flux (900 L m −2 h −1 ), with no decrease in efficiency and flux after 10 emulsion separation cycles. In addition, the superhydrophilic membrane has excellent durability and stability, remaining super-oleophobic underwater to sand shock, sandpaper abrasion, high saline corrosion and UV ageing. The prepared stainless steel membrane not only provides a novel anti-fouling strategy, but its excellent stability also provides some new inspiration for the treatment of oil and water pollution in the future.
研究领域:
材料科学
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环境工程
·
仿生学
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DOI
高影响因子
Acta Biomaterialia
·
2023
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IF 9.7
Yuelin Lv,Cuihong Chen,Liguo Jin,Yufeng Zheng,Shuilin Wu,Yu Zhang,Zhaoyang Li,Shengli Zhu,Hui Jiang,Zhenduo Cui,Xiangmei Liu
Owing to its deep penetration capability, microwave (MW) therapy has emerged as a promising method to eradicate deep-seated acute bone infection diseases such as osteomyelitis. However, the MW thermal effect still needs to be enhanced to achieve rapid and efficient treatment of deep focal infected areas. In this work, the multi-interfacial core-shell structure barium sulfate/barium [email protected] (BaSO 4 /BaTi 5 O 11 @PPy) was prepared, which exhibited enhanced MW thermal response via the well-designed multi-interfacial structure. To be specific, BaSO 4 /BaTi 5 O 11 @PPy achieved rapid temperature increases in a short period and efficient clearance of Staphylococcus aureus ( S. aureus ) infections under MW irradiation. After 15 min MW irradiation, the antibacterial efficacy of BaSO 4 /BaTi 5 O 11 @PPy can reach up to 99.61 ± 0.22%. Their desirable thermal production capabilities originated from enhanced dielectric loss including multiple interfacial polarization and conductivity loss. Additionally, in vitro analysis illuminated that the underlying antimicrobial mechanism was attributed to the noticeable MW thermal effect and changes in energy metabolic pathways on bacterial membrane instigated by BaSO 4 /BaTi 5 O 11 @PPy under MW irradiation. Considering remarkable antibacterial efficiency and acceptable biosafety, we envision that it has significant value in broadening the pool of desirable candidates to fight against S. aureus -infected osteomyelitis. Statement of significance The treatment of deep bacterial infection remains challenging due to the ineffectiveness of antibiotic treatment and the susceptibility to bacterial resistance . Microwave (MW) thermal therapy (MTT) is a promising approach with remarkable penetration to centrally heat up the infected area. This study proposes to utilize the core-shell structure BaSO 4 /BaTi 5 O 11 @PPy as an MW absorber to achieve localized heating under MW radiation for MTT. In vitro experiments demonstrated that the disrupted bacterial membrane is primarily due to the localized high temperature and interrupted electron transfer chain. As a consequence, its antibacterial rate is as high as 99.61% under MW irradiation. It is shown that the BaSO 4 /BaTi 5 O 11 @PPy is a promising candidate for eliminating bacterial infection in deep-seated tissues.
研究领域:
材料科学
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生物医学工程
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微生物学
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DOI
PubMed
高影响因子
JOURNAL OF POWER SOURCES
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2023
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IF 9.2
Shiguo Jin,Zhuo Chen,Shuai Bai,Yining Zhang
The commercialization of the Zn-metal battery is hindered by dendrites and side reactions on the Zn anode. Here, the BaSO 4 coating is designed to address the problem of the Zn anode. The porous structure of the BaSO 4 coating improves the wettability to induce relatively uniform electrolyte flux and inhibits the two-dimensional diffusion of Zn 2+ , suppressing the growth of dendrites on the Zn anode. The BaSO 4 leads to a “space charge polarization” to promote the separation of positive and negative charge centers, the electrostatic effect promotes the transportation of Zn 2+ and reduces the occurrence of side reactions. Consequently, the BaSO 4 @Zn||BaSO 4 @Zn battery displays a longer lifespan (122 h–1200 h) and a lower polarization (74.0 mV–47.2 mV) at 2 mA cm −2 . The full battery exhibits an extended lifespan (3000 cycles) and a stable coulombic efficiency at 5 A g −1 when coupled with the K 2 V 6 O 16 ·1.5H 2 O (KVO) cathode. This work serves as a reference for solving problems and promoting the application of the Zn-metal battery.
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高影响因子
ChemPlusChem
·
2026
·Vol. 91
·期 2
·e202500425
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IF 3.1
Shuyue Wu,Rongkang Yu,Mayakrishnan Arumugam,Zhichao Sun,Han Zhang,Xiangdong Kong
Transcatheter arterial embolization (TAE) is a minimally invasive interventional procedure performed under X-ray guidance. It involves catheter-based delivery of embolic agents (EAs) into pathological or injured blood vessels to block the blood supply, thereby achieving rapid hemostasis. Meanwhile, this technique induces ischemic necrosis of tumor cells by depriving them of nutrients and oxygen through targeted vascular occlusion. Owing to its advantages of minimal invasiveness, precise targeting, and repeatability, TAE has been widely adopted in clinical practice. However, its therapeutic efficacy is mainly constrained by two limitations: insufficient imaging stability caused by the rapid dispersion of radiopaque agents in the blood vessels, as well as the chemotherapy resistance induced by lactic acid accumulation in the tumor microenvironment due to embolization. In this study, we developed a novel bifunctional gelatin-based embolic microsphere that can simultaneously meet the requirements of promoting the drug uptake by tumor tissues and stable X-ray imaging through encapsulating sodium bicarbonate nanoparticles and barium sulfate (BaSO 4 ) contrast agents into the gelatin embolic microsphere. We further systematically evaluated its physicochemical and biocompatibility properties. This study provides a novel strategy for developing EAs with integrated radiopacity stability and improved drug uptake, holding potential for advancing precision in interventional therapies. Graphical We developed a novel bifunctional gelatin-based embolic microsphere that can simultaneously meet the requirements of promoting the drug uptake by tumor tissues and stable X-ray imaging by encapsulating sodium bicarbonate nanoparticles and barium sulfate contrast agents within the gelatin embolic microsphere.
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DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
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2023
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IF 9.5
Shenyi Tang,Junjie Yang,Biao Wu,Jing Zhang,Jianxin Li,Benqiao He,Hong Wang,Zhenyu Cui
In this work, the organic-inorganic hybrid separation layer containing BaSO 4 or CaC 2 O 4 was fabricated on the membrane outer surface through the combination of polyvinylamine (PVAM)-tannic acid (TA)-metal ion co-deposition, dual cross-linking and biomineralization . Based on the synergistic coordination effect between TA and PVAM, metal ions were anchored within the separation layer. The strong interaction ability between functional groups of organics and metal ions enhanced the attaching stability of mineralized substances. Characterizing the chemical composition, hydrophilicity, microstructure, and potential of the NF membrane's outer surface allowed for a thorough investigation and comparison of the impact of mineralized substances on the separation performance of NF membrane. The results indicated that the introduction of mineralized substances provided the permeance path for water molecule and reduced the water transmission resistance, which not only increased the permeability (53.4 L m −2 h −1 bar −1 ) by 2.7 times, but also remained ultrahigh removal capacity for both Mg 2+ and Ca 2+ (>99%). Furthermore, the NF membrane also exhibited satisfactory acid resistance, anti-fouling capacity and favorable operation stability. This work demonstrated excellent potential in wastewater recovery and rapid desalination, serving as a reference for the development of high-performance NF membrane with positively charged surface.
研究领域:
材料科学
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环境工程
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DOI
高影响因子
RSC Advances
·
2015
·Vol. 5
·期 97
·79774-79782
·
IF 3.84
Haiyang Jin,Yangbo Huang,Hao Li,Ping Yu,Yunbai Luo
Novel BaSO4-based mineralized thin-film composites (TFC) as forward osmosis (FO) membranes were fabricated through depositing barium sulfate on the surface of the prepared polysulfone/polyamide (PSf/PA) membranes by adopting an approach named surface mineralization. BaSO4 particles were deposited by an alternate soaking process (ASP) with aqueous solutions of barium chloride (BaCl2) and sodium sulfate (Na2SO4), separately. Membranes with different mineralization degrees were prepared by changing the number of ASP cycles. The mineralized TFC PSf/PA FO membranes were characterized by a variety of methods in accordance with membranes structure and surface properties. It turned out that the mineral coating made of BaSO4 particles was evenly distributed on the membrane surface and the existence of this coating made the membrane surface became more hydrophilic and negatively charged after mineralization. The FO performances of the mineralized TFC membranes were also tested and compared with the original PSf/PA membrane and the commercial CTA-W FO membrane with pure water as the feed solution and a 1 M NaCl solution as the draw solution. The mineralized TFC PSf/PA membranes displayed better water permeability and salt rejection than the original PSf/PA membrane and the commercial FO membrane. The results revealed that mineralized TFC PSf/PA membranes showed great potential for further development of FO applications.
研究领域:
材料科学
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环境工程
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DOI
高影响因子
CELLULOSE
·
2020
·Vol. 27
·期 9
·5169-5178
·
IF 4.21
Yang Jin,Xie Atian,Cui Jiuyun,Chen Yangyang,Lang Jihui,Li Chunxiang,Yan Yongsheng,Dai Jiangdong
With the increase of oil spills, leakage of chemical products and discharge of oily wastewater, oil–water separation has become an urgent problem. In this study, polydopamine (PDA) was first coated on the surface of paper fibers (PF@PDA) by CuSO 4 /H 2 O 2 triggering to accelerate the reaction rate. Then, the BaSO 4 nanosheets were deposited on the surface of PF@PDA membrane by alternating soaking process (ASP) to obtain superhydrophilic/underwater superoleophobic membrane (PF@PDA/BaSO 4 ) for oil/water separation. PF@PDA/BaSO 4 shows good separation efficiency (more than 99%) and high flux (more than 550 L m −2 h −1 ) for various oil–water mixtures. Importantly, the membrane shows excellent acid, alkali and salt resistance that maintains the high separation performance even under acid, base and salt solution environments. Moreover, the PF@PDA/BaSO 4 membrane has excellent antifouling property and outstanding reusability. Our PF@PDA/BaSO 4 with low cost, easy preparation and high performance has a good application prospect for oil/water separation even in harsh environments.
研究领域:
材料科学
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环境科学
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DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2023
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IF 5.2
Luping Chen,Shixiang Liu,Fengyuan Gao,Hailin Cong,Bing Yu,Youqing Shen
Transcatheter arterial chemoembolization (TACE) is one of the common methods of treating tumors and usually requires an accompanying injection of an exogenous contrast agent, but the exogenous contrast agent is highly susceptible to removal by blood flow , which greatly reduces the efficiency of the operation. Here, we developed a uniformly sized Ag 2 S/BaSO 4 /DOX@PEGDAMS that integrates embolization, drug loading, and visualization with a microfluidic device . The microspheres can be imaged stably under NIR-II/X-ray for a long time, and the luminescence of NIR-II is better than that of X-ray. This breaks the limitations of conventional X-ray-only imaging of embolic microspheres . The microscope images and scanning electron microscope EDS results showed that the microspheres were regularly spherical with uniform particle size, and the signature elements such as Ag, S, and Ba were uniformly distributed in the microspheres. In vitro cytotoxicity assays and apoptosis assays have demonstrated that the microspheres have good biocompatibility and can effectively inhibit tumor cell growth due to the presence of DOX. The ability of microspheres to aggregate in blood vessels and block blood flow was verified by modeling and embolizing in rabbit ear tumors. In conclusion, Ag 2 S/BaSO 4 /DOX@PEGDAMS shows excellent embolization, drug loading, and imaging capabilities, and has the potential to be used for TACE and other diseases requiring interventional embolization therapy.
研究领域:
生物医学工程
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药学
·
癌症治疗
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材料科学
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产品关联
DOI
高影响因子
Journal of Coatings Technology and Research
·
2022
·Vol. 20
·期 2
·587-601
·
IF 2.339
Lin Yating,Song Chunmei,Xiao Xiong,Wan Bo
Hydrophobically modified ethoxylated urethane (HEUR) with different structures was synthesized and confirmed by gel permeation chromatography, Fourier transform infrared spectroscopy and nuclear magnetic resonance ( 1 H NMR). We propose the relationship between the temperature insensitivity model and the thickening mechanism of HEUR/latex/Fe 2 O 3 /Zn 3 (PO 4 ) 2 /BaSO 4 suspensions. Meanwhile, the temperature insensitivity of HEUR/C suspensions is the result of two main associations: intermolecular interactions bridging the hydrophobic tails of HEURs and the hydrophobic groups tightly adsorbing onto the latex particle surfaces. A smaller ratio of viscosity (Rv) at 1 s −1 from the steady state condition indicates the better temperature insensitivity of viscosity. The higher degree of crystallinity and rheological activation energy corresponds to a great extent with better temperature insensitivity due to stronger association. The temperature insensitivity is consistent with the longer hydrophobic chain, which was proven by hysteresis tests and oscillatory shear measurements. The storage stability was enhanced in the lockstep with a hydrophobic length of HEUR, which is consistent with the rougher surfaces of HEUR/C films. As an appealing method, the results are meaningful and instructive for coating storage and application. Graphical abstract
An intermolecular network model of HEUR/C is presented, which suggests intermolecular associations in the bridging of hydrophobic tails and the hydrophobic groups adsorbing onto the latex particle surfaces. A temperature insensitivity mechanism model combined with rheology results and AFM is also proposed to clarify the relationship between temperature insensitivity and storage stability and the hydrophobic tail length.
研究领域:
材料科学
·
化学工程
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DOI
高影响因子
危险品化学品经营许可证（带存储）