APPLIED SURFACE SCIENCE
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2024
·
IF 6.3
Shi-Ming Niu,Xin-Hui Li,Hao-Yang Ding,Wo-Long Wang,Peng-Fei Li,Xia-Chen Zheng,Min-Hua Cui
The application of heterogeneous photocatalysts is severely limited by the high charge transfer resistance (R ct ). BiVO 4 /g-C 3 N 4 photocatalysts were prepared and loaded on the conductive matrix material carbon paper (CP) to reduce electron transfer resistance and improve the photocatalytic performance. The R ct of BiVO 4 /g-C 3 N 4 @CP was remarkedly reduced by 94.3 % compared to the photocatalysts on the oil paper (BiVO 4 /g-C 3 N 4 @OP), while the photocurrent density increased by 5.5 times. The utilization efficiency of light energy and separation of photoelectrons and holes were improved with CP due to its ability to facilitate long-distance transfer of photoelectrons. Consequently, the photocatalytic degradation performance of BiVO 4 /g-C 3 N 4 @CP was enhanced by a 26.1 % improvement in ciprofloxacin (CIP) degradation efficiency. Quenching experiment, LC-MS analysis and DFT calculation revealed that piperazine ring opening and C-F cleavage were the major pathways for CIP degradation with BiVO 4 /g-C 3 N 4 @CP.
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高影响因子
Nanomaterials
·
2025
·Vol. 15
·期 5
·383
·
IF 4.3
Haonan Chi,Pan Cao,Qi Shi,Chaoyu Song,Yuguang Lv,Tai Peng
This study synthesized graphene oxide (GO)/zinc oxide (ZnO)/silver (Ag) composite materials and investigated their photocatalytic degradation performance for ciprofloxacin (CIP) under visible light irradiation. GO/ZnO/Ag composites with different ratios were prepared via an impregnation and chemical reduction method and characterized using X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FT-IR), and X-ray photoelectron spectroscopy (XPS). The results demonstrated that under optimal conditions (20 mg/L CIP concentration, 15 mg catalyst dosage, GO/ZnO-3%/Ag-doping ratio, and pH 5), the GO/ZnO/Ag composite exhibited the highest photocatalytic activity, achieving a maximum degradation rate of 82.13%. This catalyst effectively degraded ciprofloxacin under light irradiation, showing promising potential for water purification applications.
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高影响因子
Applied Water Science
·
2024
·Vol. 14
·期 9
·1-10
·
IF 5.7
Afzal Muhammad Zaheer,Khan Said Akbar,Song Chao,Irfan Muhammad Imran,Wang Shu-Guang
Growing concerns regarding the presence of pharmaceuticals in wastewater necessitate their removal. Membrane filtration offers a promising approach. This study explores the development of biochar incorporated mixed matrix membranes (MMMs) for ciprofloxacin removal from water. Biochar, derived from the pyrolysis of agricultural waste, was blended with polyether sulfone (PES) and polyvinylpyrrolidone in varying ratios. The resulting MMMs exhibited progressively improved properties with increasing biochar content. Notably, membrane M 11 , comprising equal parts PES and biochar, displayed the highest porosity, lowest surface roughness (12.0), and lowest contact angle (31.05°), indicating enhanced hydrophilicity (increased by 58.19% compared to the biochar-free membrane). M 11 effectively removed ciprofloxacin along with three additional antibiotics from different classes. Fourier-transform infrared spectroscopy and X-ray photoelectron spectroscopy analyses corroborated the removal of ciprofloxacin. Furthermore, M 11 demonstrated excellent regenerability, retaining over 57% removal efficiency after four cycles. These findings highlight the potential of M 11 as a sustainable and cost-effective membrane for pharmaceutical removal from wastewater.
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Frontiers of Environmental Science & Engineering
·
2020
·Vol. 14
·期 3
·1-10
·
IF 4.053
Yang Zhenyu,Xing Rong,Zhou Wenjun,Zhu Lizhong
The g-MoS 2 coated biochar (g-MoS 2 -BC) composites were synthesized by coating original biochar with g-MoS 2 nanosheets at 300°C(BC300)/700°C (BC700). The adsorption properties of the g-MoS 2 -BC composites for ciprofloxacin (CIP) were investigated with an aim to exploit its high efficiency toward soil amendment. The specific surface area and the pore structures of biochar coated g-MoS 2 nanosheets were significantly increased. The g-MoS 2 -BC composites provided more it electrons, which was favorable in enhancing the it-it electron donor-acceptor (EDA) interactions between CIP and biochar. As a result, the g-MoS 2 -BC composites showed faster adsorption rate and greater adsorption capacity for CIP than the original biochar. The coated g-MoS 2 nanosheets contributed more to CIP adsorption on the g-MoS 2 -BC composites due to their greater CIP adsorption capacity than the original biochar. Moreover, the synergistic effect was observed for CIP adsorption on g-MoS 2 -BC700, and suppression effect on g-MoS 2 -BC300. In addition, the adsorption of CIP onto g-MoS 2 -BC composites also exhibited strong dependence on the solution pH, since it can affect both the adsorbent surface charge and the speciation of contaminants. It was reasonably suggested that the mechanisms of CIP adsorption on g-MoS 2 -BC composites involved pore-filling effects, it-it EDA interaction, electrostatic interaction, and ion exchange interaction. These results are useful for the modification of biochar in exploiting the novel amendment for contaminated soils.
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JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS
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2024
·
IF 1.5
Fang Yang,Long-Ji Sun,Fan Yang,Shi-Hao Li,Yu-Xin Chen,Wen-Rui Wang
The objective of this study was to determine the pharmacokinetics of enrofloxacin and its metabolite, ciprofloxacin, in Nanyang cattle after a single intravenous (IV), and intramuscular (IM) administration of enrofloxacin at 2.5 mg/kg body weight (BW). Blood samples were collected at predetermined time points. Enrofloxacin and ciprofloxacin concentrations in plasma were simultaneously determined using a high-performance liquid chromatography (HPLC) assay method and subjected to a non-compartmental analysis. After IV administration, enrofloxacin had a mean (±SD) volume of distribution at steady state ( V SS ) of 1.394 ± 0.349 L/kg, a terminal half-life ( t 1/2 λz ) of 3.592 ± 1.205 h, and a total body clearance (Cl) of 0.675 ± 0.16 L/h/kg. After IM administration, enrofloxacin was absorbed relatively slowly but completely, with a mean absorption time (MAT) of 6.051 ± 1.107 h and a bioavailability of 99.225 ± 7.389%. Both compounds were detected simultaneously in most plasma samples following both routes of administration, indicating efficient biotransformation of enrofloxacin to ciprofloxacin. After IV injection, the peak concentration ( C max ) of ciprofloxacin was 0.315 ± 0.017 μg/mL, observed at 0.958 ± 0.102 h. Following IM injection, the corresponding values were 0.071 ± 0.006 μg/mL and 3 ± 1.095 h, respectively. Following IV and IM administration, the conversion ratio of enrofloxacin to ciprofloxacin was calculated as 59.2 ± 9.6% and 31.2 ± 7.7%, respectively. The present results demonstrated favorable pharmacokinetic profiles for enrofloxacin, characterized by complete absorption with relatively slow kinetics, extensive distribution, efficient biotransformation to ciprofloxacin, and prolonged elimination in Nanyang cattle.
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Algal Research-Biomass Biofuels and Bioproducts
·
2023
·
IF 5.1
Yue Wang,Weihao Ning,Meina Han,Changfei Gao,Wanqian Guo,Jo-Shu Chang,Shih-Hsin Ho
The ciprofloxacin treating via microalga and its microalgae-bacteria consortium was investigated for discussing the potential application of microalgae-mediated bioremediation. As results, the maximum removal efficiency of ciprofloxacin by pure microalgae and the consortium was 87.5 ± 3.5 % (5 mg/L) and 96.1 ± 0.07 % (40 mg/L), respectively. The consortium enhanced the degradation rate to 0.81 d −1 compared with the pure microalgae (0.27 d −1 ). To reveal the symbiotic mechanism, extracellular polymeric substances , pigments contents, antioxidant enzymes and symbiotic bacterial community were analyzed. The malondialdehyde content in the pure microalgae (1622.6 ± 38.7 nmol/mg protein) was higher than that in the consortium (298.34 ± 2.4 nmol/mg protein), and there were obvious chlorophyll b accumulations (approximately 90 %) in consortium. In addition, the symbiotic bacteria had a positive effect on microalgal secretion of fulvic acid-type components. As mechanism, symbiotic bacteria improved ciprofloxacin biodegradation by reducing cell damage and secreting fulvic acid . The presence of Phycisphaeraceae and Rhizobiaceae , nitrogen fixation bacteria, in the consortium suggest that improvement of ciprofloxacin biodegradation might be associated with nitrogen co-metabolism as well. Collectively, this work elucidates the mechanism of enhancing elimination of ciprofloxacin via microalgae-bacteria consortium and accelerates development of microalgae-mediated aquaculture tailwater bioremediation.
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Journal of Environmental Chemical Engineering
·
2023
·
IF 7.7
Guo Chen,Jun Wu,Jing Ma,Min Xu,Lulu Long,Chao Chen,Xiaohong Zhang,Gang Yang,Chun Song,Yinlong Xiao,Peng Gao,Linling Li
Understanding ciprofloxacin (CIP) sorption behavior onto purple soil is essential to minimize the associated environmental risks. However, CIP sorption onto the different components of purple soil and its underlying mechanisms are poorly understood. We performed a sorption experiment using original purple soils (Dayi soil (D ORI ) and Ya'an soil (Y ORI )), soils without dissolved organic matter (DOM) (D IOM and Y IOM : insoluble organic matter remaining), and soils without organic matter (OM) (D M and Y M : minerals remaining) to explore the CIP sorption behavior. Compared with D ORI and Y ORI , the CIP sorption capacity of D M and Y M decreased by 67.1% and 75.7%, indicating that the CIP sorption capacity was mainly contributed by OM. Compared with D ORI and Y ORI , the CIP sorption capacity of D IOM and Y IOM increased by 17.1% and 12.6%, suggesting that DOM in soil affected CIP sorption in purple soil. Redshifts and blueshifts confirmed that H-bonds and π-π interaction dominated the CIP sorption onto OM. CIP sorption was fitted by the Langmuir model, indicating monomolecular sorption. Compared with D ORI and Y ORI , the K L of D M and Y M was higher, implying that CIP sorption was faster and easier on minerals than on OM. Compared with K + , Ca 2+ had a stronger hydration capacity but lower CIP sorption capacity in D M , suggesting that the stronger hydration capacity of cations was not conducive to CIP adsorption onto minerals and proving that the hydrophobic effect drove CIP adsorption. These mechanistic insights have important implications for understanding CIP sorption in purple soil.
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ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
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2022
·
IF 7.129
Lirui Hou,Yuhan Fu,Chong Zhao,Lihong Fan,Hongbo Hu,Shutao Yin
Ciprofloxacin (CIP) and enrofloxacin (ENR) are veterinary antibiotics commonly utilized to treat and prevent animal diseases. Environmental and dietary antibiotic residues can directly and indirectly affect the reproductive development of animals and humans. This article investigated the reproductive toxicity of CIP in male zebrafish, showing that it could decrease the spermatogonial weight and damage the spermatogonial tissue. The sex hormone assays showed that CIP decreased fshb and lhb gene expression and plasma testosterone (T). In addition, transcriptome analysis indicated that the effect of CIP on zebrafish might be related to the endocrine signaling pathways. ENR, which was selected for further study, inhibited mouse Leydig (TM3) and Sertoli (TM4) cell proliferation and caused cell cycle arrest. The sperm concentration, serum luteotropic hormone (LH) and follicle-stimulating hormone (FSH), and T levels decreased in adolescent mice after ENR treatment for 30d in vivo. Hematoxylin and eosin (H&E) staining showed that ENR exposure potentially induced testicular injury, while the real-time quantitative PCR (qPCR) results indicated that ENR inhibited the mRNA expression of key genes in the Leydig cells (cyp11a1, 3β-HSD, and 17β-HSD), Sertoli cells (Inhbβ and Gdnf) and spermatogenic cells (Plzf, Stra8 and Dmc1). In conclusion, these findings indicated that ENR exposure might influence the development of the testes of pubescent mice.
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高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2022
·
IF 9.965
Chichi Ruan,Guanyu Chen,Yuanshneg Ma,Chunhua Du,Chunxiang He,Xinyu Liu,Xin Jin,Qilin Chen,Song He,Yajun Huang
Efforts to develop a green, inexpensive and effective adsorbent are crucial for eliminating antibiotics in polluted water. The sorption capacity of the as-prepared polyvinyl alcohol (PVA)-assisted cellulose nanocrystals/SiO 2 (CNCs/SiO 2 ) composite aerogel to ciprofloxacin (CIP) rises with the increase of temperature and initial concentration. Reverse trend of sorption capacity can be found when increasing the adsorbent dosage of adsorbent. The optimal pH value for the sorption is proved to be 4. It’s found in the uniaxial compression test that the maximum load that PVA-assisted aerogels can withstand is nearly 100 times than that of non-PVA aerogels. Sorption results confirm that the Pseudo-second order (R 2 = 0.9885) and Langmuir models (R 2 = 0.9959) fit well to sorption kinetics and equilibrium data, respectively. The rate constant differs from the initial concentration of CIP according to the Pseudo-second order model. The composite aerogel sorption capacity of Langmuir (q max ) for CIP was 163.34 mg·g −1 . The thermodynamic studies showed that the sorption process is endothermic with the value of enthalpy change of 41.032 kJ/mol. Hydrogen bonding , π–π interaction, hydrophobic and electrostatic interactions are the dominant mechanisms of CIP sorption by the PVA-assisted CNCs/SiO 2 composite aerogel.
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JOURNAL OF HAZARDOUS MATERIALS
·
2020
·
IF 9.038
Can Meng,Du Huan,Hai-Ming Zhao,Sha Li,Hui Li,Yan-Wen Li,Quan-Ying Cai,Ce-Hui Mo
How nitrate (NO 3 − ) fertilization influences ciprofloxacin (CIP) uptake by crops remains unsolved. Here, two Brassica parachinensis cultivars differing in CIP accumulation were cultivated to investigate the effects of NO 3 − supply on CIP uptake and the underlying mechanism. The results showed that NO 3 − supply effectively reduced CIP toxicity and accumulation in the two cultivars, especially in the low CIP cultivar. Moreover, NO 3 − supply induced different mechanisms of coping with CIP stress in the two cultivars through influencing subcellular distribution of CIP. The uptake of CIP by root was demonstrated to be a carrier-mediated, energy-consuming, and proton motive force-dependent influx process. Consequently, a mechanism of nitrate supply decreasing CIP uptake was proposed that uptake of CIP and NO 3 - into root cell would compete for the proton motive force and share a common energy source provided by plasma membrane H + -ATPase. Besides, regulating the concentration balances of cytoplasmic NO 3 - and proton by inhibiting the activities of NRase and two tonoplast proton pumps (V-ATPase and V-PPase) led to opposite effect on CIP uptake, further supporting this inference. Our results provide a novel insight into CIP uptake by plant roots, and improve the strategy of minimizing CIP accumulation in crops for food safety by fertilization management.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2015
·
IF 3.368
Jian-Rong Li,Yun-Xia Wang,Xu Wang,Baoling Yuan,Ming-Lai Fu
The hydrothermally synthesized layered chalcogenide, K 2 x Mn x Sn 3− x S 6 ( x = 0.5–0.95) (KMS-1), was applied to remove ciprofloxacin from aqueous solution. Kinetic data showed the removal reaction followed a pseudo-second-order kinetic model and the rate controlling step was both through external film and intraparticle diffusion . The adsorption of CIP by KMS-1 is endothermic and the maximum adsorption capacity of KMS-1 was 199.6, 230.9 and 269.5 mg/g at temperature of 10, 25 and 40 °C, respectively. The heavy metal ions had great effect on the removal efficiency of CIP and the degree of inhibition followed the order: Pb 2+ > Zn 2+ > Cd 2+ > Ni 2+ . The shift of Bragg peaks from XRD at various pH accompanying CIP removal and FE-SEM images confirmed that cation exchange is the major mechanism for the adsorption of CIP by KMS-1. In the pH range of 4.0–7.0, the intercalation of cationic CIP adopted a titled orientation of di-molecular CIP in KMS-1 with the titling angle of 68° and 42°, respectively. A vertical arrangement of the zwitterionic CIP adsorbed on the surface of KMS-1 was also confirmed. These results suggested that KMS-1 is an effective adsorbent to remove CIP from water.
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高影响因子
Energy Materials
·
2025
·Vol. 5
·期 1
·N
·
IF 11.2
Yang Zhou,Ciyuan Huang,Linji Yang,Ruirui Zhang,Yanzhen Yin,Cong Liu,Ke Sun,Shangfei Yao,Nannan Geng,Yu Luo,Tao Yang,Bingsuo Zou,Tao Liu
Antibiotics, as emerging organic pollutants, have seriously affected the biodiversity of water and threatened mankind’s health. Currently, low charge separation efficiency and insufficient light utilization limit the application of traditional photocatalysts in antibiotic degradation. In this work, the organic photovoltaic material PM6: Y6 was incorporated into an organic photocatalyst with bulk-heterojunction, and a third component, 3,9-bis{2-methylene-[3-(1,1-dicyanomethylene)-cyclopentane-1,3-dione-(c)thiophen]}-5,5,11,11-tetrakis(4-hexylphenyl)-dithieno[2,3-d:2’,3’-d’]-s-indaceno[1,2-b:5,6-b’]dithiophene (ITCPTC), was added to adjust the absorption spectrum of photocatalyst for efficient photodegradation of ciprofloxacin (CIP). Benefiting from excellent light utilization and effective carrier separation and transfer, the catalyst exhibited excellent photocatalytic performance, achieving a 90%/99% degradation rate of CIP within 30/60 min under simulated sunlight irradiation (~79 mW/cm2). Besides, the catalyst still exhibited good photocatalytic performance after multiple cycles of use. By Electron Spin Resonance analysis, the active species for photocatalytic degradation of CIP were mainly holes (h+) and superoxide radicals (·O2-). Designing photocatalysts with a wider light absorption range and better charge separation is a feasible idea to achieve better photocatalytic performance. It is anticipated that this work could enhance the understanding of modification strategies for ternary organic semiconductors and expand the application of photocatalysis in environmental pollution control and remediation.
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