APPLIED SURFACE SCIENCE
·
2020
·
IF 6.182
Dongxu Zhu,Lijin Wang,Zheming Liu,Aiwei Tang
Cubic Cu 2−x Se nanocrystals (NCs) exhibit a strong localized surface plasmon resonance (LSPR) absorption in the near-infrared (NIR) region, in which the LSPR wavelength and stability are significant for the NIR-region applications in photo-thermal therapy and photoacoustic imaging. Herein, we have systematically studied the effects of surface ligands with varying the feeding ratio of oleylamine (OM) to oleic acid (OA) on LSPR behavior and stabilization of Cu 2−x Se NCs, which were synthesized by using a typical hot-injection method. The LSPR wavelength of the as-obtained Cu 2−x Se NCs could be tuned from 1260 to 1030 nm with an increase of the feeding ratio of OM to OA. Furthermore, these Cu 2−x Se NCs showed different LSPR stability with varying feeding ratios of OM to OA. For the Cu 2−x Se NCs synthesized in the presence of only OM, the LSPR could keep stable basically after exposure to air for 60 days. However, in the feeding ratio of OM to OA of 7:3 and 5:5 cases, the LSPR extinction spectra showed an obvious blue-shift in the wavelength. The characterized results indicated the different surface ligands had significant effects on the LSPR behavior and stabilization, and the LSPR change was in good agreement with the calculated results based on the Mie-Drude model. This work provides a new research idea for tuning the LSPR behavior of copper chalcogenide NCs.
研究领域:
材料科学
·
纳米医学
·
光热治疗
·
光声成像
✓ 已验证
产品关联
DOI
高影响因子
ACS Sensors
·
2016
·
IF 0
Hui Zhang,Yunsheng Xia
In this study, we have reported a new colorimetric platform for sensitive and selective sensing of Hg2+ using near-infrared (NIR) plasmonic Cu2-xSe nanoparticles (NPs) as reporters. Because of ultrahigh affinity between Hg2+ and Se2–, the added Hg2+ can react with Cu2-xSe NPs and exchange their Cu+/Cu2+, yielding a HgSe layer around the host NPs. Accordingly, the absorption profiles of the Cu2-xSe NPs are modulated substantially: The absorbance at 400–600 nm is increased, and the NIR localized surface plasmon resonance dramatically decreases with a more than 150 nm bathochromic shift. Thus, the system possesses triple signal responses, namely, ratiometry, wavelength, and intensity, to the analytes simultaneously. Such uniquely multiple signal output not only provides more choices for the quantification, but also enhances the reliability in the analyte detection. By rationally choosing poly(allylamine hydrochloride) as the NP template, Hg2+ ions can be determined as ranging from 0–800 nM. The detection limit is as low as 2.7 nM, which is nearly 4 times lower than the limit value (10 nM) defined by the U.S. Environmental Protection Agency for drinking water. Other heavy/transition metal ions, such as Cu2+, Ag+, Pb2+, Cd2+, Ni2+, Co2+, Mn2+, Zn2+, Cr3+, Fe2+, and FeF63–, do not interfere with the sensing. Especially, Hg2+ contents can be quantified, even if their concentrations are as low 10 nM in tap water and common environmental water samples. Due to favorable analytical performance, the proposed Cu2-xSe NPs based system has potential applications in monitoring trace Hg2+ in various real samples, even in drinking water.
研究领域:
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
Nanoscale
·
2018
·Vol. 10
·期 30
·14546-14553
·
IF 7.233
Dandan Xie,Bin Zhang,Aijuan Zhang,Yongjin Chen,Yanci Yan,Hengquan Yang,Guiwen Wang,Guoyu Wang,Xiaodong Han,Guang Han,Xu Lu,Xiaoyuan Zhou
(Ag,Sn) co-doped Cu3SbSe4 nanocrystals are obtained via a facile microwave-assisted solvothermal method, and their thermoelectric properties are investigated in the temperature range from 300 K to 623 K. Sn-doping on Sb sites dramatically increases the carrier concentration and thus the electrical conductivity, promoting the thermoelectric power factor. Further alloying with Ag on Cu sites strongly suppresses the lattice thermal conductivity close to the glass limit. Aside from point defect scattering, such reduction in lattice thermal conductivity largely relies on the formation of Cu2−xSe nanoinclusions, which serve as additional scattering centers for phonons. Overall, the sample with the nominal composition of Cu2.8Ag0.2Sb0.95Sn0.05Se4 reaches a minimum lattice thermal conductivity of 0.27 W m−1 K−1 and a maximum zT of 1.18 at 623 K, which is the best result for the Cu3SbSe4-based materials in the same temperature region. Our results demonstrate that the microwave-assisted synthesis method is capable of fabricating Cu based ternary compounds with high thermoelectric performance.
研究领域:
材料科学
·
热电材料
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ChemSusChem
·
2017
·Vol. 10
·期 10
·2235-2241
·
IF 7.226
He Li,Jiali Jiang,Feng Wang,Jianxing Huang,Yunhui Wang,Yiyong Zhang,Jinbao Zhao
A rod-like Cu 2− x Se is synthesized by a facile water evaporation process. The electrochemical reaction mechanism is investigated by ex situ X-ray diffraction (XRD). By adopting an ether-based electrolyte instead of a carbonate-based electrolyte, the electrochemical performance of Cu 2− x Se electrodes improved significantly. The Cu 2− x Se electrodes exhibit outstanding cycle performance: after 1000 cycles, 160 mA h g −1 can be maintained with a retention of 80.3 %. At current densities of 100, 200, 500, and 1000 mA g −1 , the capacity of a Cu 2− x Se/Li battery was 208, 202, 200, and 198 mA h g −1 , respectively, showing excellent rate capability. The 4-probe conductivity measurements along with electrochemical impendence spectroscopy (EIS) and cyclic voltammetry (CV) tests illustrate that the Cu 2− x Se electrodes display high specific conductivity and impressive lithium–ion diffusion rate, which makes the Cu 2− x Se a promising anode material for lithium–ion batteries. Graphical An ideal anode : A rod-like Cu 2− x Se is synthesized by water evaporation and its electrochemical properties in lithium–ion batteries using an ether-based electrolyte are studied and presented. Ex situ XRD is also used to investigate the electrochemical reaction mechanism.
研究领域:
材料科学
·
电化学
·
纳米材料
·
能源存储
·
无机化学
✓ 已验证
DOI
高影响因子
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
·
2022
·
IF 6.814
Guojuan Yan,Bo Kong,Jiaqiang Zhao,Huanhuan Ni,Lei Zhan,Chengzhi Huang,Hongyan Zou
The application of nanostructures to design fluorescence resonance energy transfer (FRET) based sensing platforms has been greatly concerned with the demand for sensitive and selective detection of biomolecules. Here, a novel sensitive turn-on fluorescence strategy based on the FRET mechanism has been designed for hyaluronidase (HAase) detection through the modulation of Cu 2-x Se@HA-Rh6G nanoprobe fabricated by self-assembly of rhodamine 6G (Rh6G) together with Cu 2-x Se@HA nanoparticles through electrostatic adsorption. The Cu 2-x Se@HA had extensive localized surface plasma resonance (LSPR) absorption in the wide range of ultraviolet (UV) to near-infrared (NIR) wavelengths and showed good light capture characteristics, which can be acted as good acceptors in the FRET interactions with Rh6G , inducing its efficient fluorescence quenching . In the presence of HAase, the FRET process was disrupted and the fluorescence signal was recovered. In the range of 0.1–10.0 U/mL, the fluorescence recovery of Rh6G showed a good linear relationship with the concentration of HAase, and the detection limit was 0.06 U/mL. The sensing platform has been used for HAase detection in real urine samples and cancer cells imaging.
研究领域:
纳米技术
·
生物传感
·
生物医学工程
·
分析化学
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Particuology
·
2022
·
IF 3.251
Bei Li,Jing Li,Yi Fu,Xiwen Ye,Maodi Xie,Lei Feng,Xiaoya Niu,Zhen You
Laser mediated photothermal/chemodynamic co-therapy is widely applied for anti-cancer treatment due to its good therapeutic effect. However, the laser wavelength for effectively targeting deep tumor tissues can decide whether or not it is a key premise of irradiation treatment. In this study, a super-homogenous and highly dispersive spherical nanoparticle Cu 2-X Se was prepared, which displayed a strong surface plasmon resonance (SPR) peak in the near-infrared region (NIR)-II and high Fenton catalytic efficiency. The results of in vitro experiments showed that Cu 2-X Se nanoparticles exhibited high photothermal conversion efficiency under the excitation of NIR-II laser irradiation, which significantly improved its ability to produce ·OH. In a tumor-bearing mouse model, the combination of Cu 2-X Se and photothermal/chemodynamic co-therapy guided by the real-time photoacoustic imaging in the NIR-II could effectively inhibit tumor growth and exhibit good in vivo/in vitro biocompatibility. In summary, this Cu 2-X Se nanoparticle-based NIR-II laser-mediated photothermal/chemodynamic co-therapy strategy is expected to provide a new option for the diagnosis and treatment of liver cancer.
研究领域:
生物医学工程
·
肿瘤学
·
纳米医学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Yaofa Liu,Haimei Li,Shulan Li,Xiaoyang Zhang,Jiaqiang Xiong,Fenglei Jiang,Yi Liu,Peng Jiang
Chiral nanomaterials have great potential in improving the clinical therapeutic effect due to the unique chiral selectivity of biosystems. However, such a promising therapeutic strategy has so far received little attention in cancer treatment. Here, we report a first chiral Fenton catalyst, d-/l-penicillamine-modified Cu2–xSe nanoparticles (d-/l-NPs), for enhanced synergistic cancer chemodynamic therapy (CDT) and photothermal therapy (PTT) under the second near-infrared (NIR-II) light irradiation. The chiral effect study of chiral Cu2–xSe NPs on cancer cells shows that d-NPs exhibit stronger CDT-induced cytotoxicity than l -NPs due to the stronger internalization ability. Moreover, the hydroxyl radicals (•OH) produced in d-NP-treated cancer cells via the CDT effect can be further improved by NIR-II light irradiation, thereby increasing the apoptosis of cancer cells. In vivo experiments show that, compared with l-NPs, d-NPs exhibit a stronger photothermal effect on the tumor site under NIR-II light irradiation and could completely eliminate the tumor under the synergistic effect of CDT and PTT. This work shows that the chirality of the surface ligand of the nanomaterials could significantly affect their cancer curative effect, which opens up a new way for the development of anticancer nanomedicine.
研究领域:
生物医学工程
·
肿瘤治疗学
·
纳米医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOMATERIALS
·
2020
·
IF 10.317
Yuanlin Wang,Zhenglin Li,Ying Hu,Jing Liu,Mengyu Guo,Hengxiang Wei,Shanliang Zheng,Tingting Jiang,Xiang Sun,Zhuo Ma,Ye Sun,Flemming Besenbacher,Chunying Chen,Miao Yu
In vivo chemical reactions activated by the tumor microenvironment (TME) are particularly promising for antitumor treatments. Herein, employing Cu 2-x Se-Au Janus nanoparticles (NPs), photothermal conversion-coordinated Fenton-like and photocatalytic reactions are demonstrated in vitro/vivo . The amorphous form of Cu 2-x Se and the catalytic effect of Au benefit the OH generation, and the photo-induced electron‒hole separation of the Janus NPs produces additional OH. The plasmonic electrons of Au facilitate the conversion from Cu 2+ to Cu + . Both Cu 2-x Se and Au contributes to the efficient photothermal conversion, further promoting the reactions. As a result, the H 2 O 2 utilization rate is largely increased, and remarkable generation of reactive oxygen species is achieved by cell endogenous H 2 O 2 in vitro/vivo . A competent tumor inhibition effect is afforded, with high-contrast multimodal imaging. This work opens up the route synergistically integrating photothermal therapy with chemodynamic therapy and photocatalytic therapy into tri-combination antitumor therapy, simply by heterojunction of semiconductor and noble metal.
研究领域:
生物医学工程
·
纳米医学
·
肿瘤学
✓ 已验证
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2021
·
IF 4.539
Xiang Xie,Wenhua Xue,Xiaoyun Hu,Hongfei Lv,Jun Fan,Bo Chen,Enzhou Liu
The Cu 2−x Se/g-C 3 N 4 heterojunction was successfully constructed using a one-step method and employed to photocatalytic H 2 evolution from water for the first time. The optimal Cu 2−x Se/g-C 3 N 4 -10 wt% exhibits an efficient H 2 evolution rate of 1954.9 μmol·g −1 ·h −1 , which is nearly 2.2 and 18.6 times higher than that of the pristine Cu 2−x Se and g-C 3 N 4 . This could owe to the improved light capturing ability, abundant active sites, efficient charge carriers’ separation for the appropriate band gap structures between Cu 2−x Se and g-C 3 N 4 . In addition, a photocatalytic H 2 production mechanism over Cu 2−x Se/g-C 3 N 4 heterojunction is analyzed based on the investigation on energy band structures and photoelectric properties of the components.
研究领域:
材料科学
·
光催化
·
能源转换
✓ 已验证
DOI
高影响因子
CHEMISTRY-A EUROPEAN JOURNAL
·
2021
·Vol. 28
·期 1
·e202102885
·
IF 5.236
Yubo Hu,Ke Wang,Cong Ye
Graphical The nanozyme@natural enzyme symbiotic system of Cu 2- x Se−GOx exhibited prominent “four-in-one” cascaded catalytic enzyme activities including catalase, peroxidase, glutathione oxidase and glucose oxidase. The ingenious Cu 2- x Se−GOx could significantly induce the accumulation of reactive oxygen species (ROS) at tumor regions; this results in a tumor microenvironment (TME)-activated “four-in-one” enzyme cascade that is lethal to cervical cancer. All in all, Cu 2- x Se−GOx can act as a high-performance and safe bioactive material for cancer treatment. Cervical cancer, as a common malignant tumor of the reproductive system, seriously threatens women‘s life and health, and is difficult to be cured by traditional treatments, such as surgery, chemotherapy and radiotherapy. Fortunately, tumor microenvironment (TME)-activated catalytic therapy with high efficiency and reduced off-target toxicity has emerged as a novel treatment model. Herein, we designed a “four-in-one” nanozyme and natural enzyme symbiotic system of Cu 2- x Se−GOx for TME-triggered cascaded catalytic enhanced cancer treatment. In response to unique TME, Cu 2- x Se with catalase activity could effectively catalyze over-expressed H 2 O 2 in cancer cells into O 2 . Subsequently, the glucose oxidase (GOx) could deplete intracellular glucose with the assistance of O 2 ; this not only achieves starvation therapy, but also regenerates H 2 O 2 to boost the generation of highly cytotoxic . OH due to the peroxidase activity of Cu 2- x Se. Moreover, although the free-radical scavenger glutathione (GSH) is overexpressed in tumor cells, Cu 2- x Se with glutathione oxidase activity could effectively consume GSH for enhanced ROS production. Thus, the “four-in-one” nanozyme@natural enzyme symbiotic system of Cu 2- x Se−GOx could induce significant ROS accumulation at the tumor regions, thus providing a potential approach for the treatment of cervical cancer.
研究领域:
癌症生物学
·
纳米技术
·
生物医学工程
·
药学
✓ 已验证
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Wenjie Zhao,Yujie Zhang,Haomiao Li,Yi Shen,Kangli Wang,Kai Jiang
Rechargeable Mg batteries with the merits of low cost, high safety and environmental compatibility are deemed as promising energy storage techniques for large-scale applications. However, the actual development of rechargeable Mg batteries is constantly hindered by the difficulty of finding suitable electrode materials to accommodate Mg 2+ . Cu 2-x Se has exceptionally high electrical conductivity and its unique crystal structure could be better compatible with Mg 2+ cations. Herein, a novel Cu 2-x Se hollow nanocube with extraordinarily high conductivity and unique structure was designed and synthesized by facile one-step template-directed selenation reaction methods. The excellent Mg electrochemical performance of Cu 2-x Se hollow nanocube cathodes was demonstrated based on rechargeable Mg batteries. The Cu 2-x Se NCs provide a high specific capacity of 232.5 mAh g - 1 at 100 mA g - 1 , superior cycling stability over 3700 cycles, and an excellent rate capacity of 163.1 mAh g - 1 at 3000 mA g - 1 . Furthermore, the two-step magnesiation/demagnesiation processes of the Cu 2-x Se NC cathodes were revealed, and the accelerating effects of the fast Mg 2+ diffusion in the unique hierarchical structure on magnesium storage performance were analyzed. The outcomes of this study not only provide simple methods for fabricating high-performance Cu 2-x Se cathodes but also propose valuable insights for exploring conversion-type Mg-storage materials.
研究领域:
材料科学
·
电化学
✓ 已验证
DOI
高影响因子
ACS Nano
·
2017
·
IF 13.942
Yu Zou,Chao Sun,Wenbin Gong,Xianfeng Yang,Xin Huang,Ting Yang,Weibang Lu,Jiang Jiang
Integrating a plasmonic metal and a semiconductor at the nanoscale is of great importance for exploring their optical coupling properties. However, the synthesis and fine structural control of such nanostructures remain challenging. Herein we report the facile aqueous-phase Se-mediated overgrowth of metal selenides onto Au nanocrystals. Taking plasmonic Cu2–xSe as an example, the introduction of a Se template allows deposition of large Cu2–xSe crystalline grains onto Au nanocrystal seeds in various shapes, including spheres, rods, and plates. Moreover, the configuration of Au–Cu2–xSe hybrids can be tuned from core–shell to heterodimer structure by controlling the growth behavior of the Se template. Se overgrowth depends critically on the absorption strength of stabilizers on Au seeds: a strongly absorbing stabilizer inhibits isotropic overgrowth, which is in agreement with molecular dynamics simulations. The resultant Au–Cu2–xSe hybrid nanocrystals possess multiple surface plasmon resonance modes. Finally, our synthetic strategy can be extended to prepare other Au–metal selenide hybrids such as Au–Ag2Se and Au–CdSe with controllable morphologies.
研究领域:
材料科学
·
纳米技术
·
光学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）