JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2020
·
IF 3.807
Anzi Yang,Xiaoxia Huangfu,Lixiao Liu,Wen Luo,Wenbo Zhao,Jun Yin
Biomedical detection needs to develop more detection methods and reagents. CuFeS 2 , an I-III-IV ternary semiconductor material, has attracted great interest of researchers because of its optical, electrical, low toxicity and controllable chemical synthesis. Here, we synthesized CuFeS 2 quantum dots (QDs) with hot-injection method and their ECL behaviors were investigated for the first time, involving the co-reactant anode/cathode ECL emission and the related ECL mechanism. Moreover, a novel ECL immunosensor based on CuFeS 2 QDs for the ultrasensitive detection of Cyclin D1 (CCND1) was designed and prepared. CuFeS 2 QDs with uniform size and excellent optical properties were used as ECL emitters and Carboxyl Fe 3 O 4 magnetic beads (MB) were utilized for magnetic separation of CCND1 from MCF-7 cells treated by sophora frevescens. In addition, reduced graphene oxide (rGO) and Au NPs by electrodeposition not only provided plentiful active sites for the immobilization of anti-CCND1 (primary antibody, Ab 1 ), but also enhanced the conductivity of the electrode. Results indicated that under the optimal condition, the ECL signal was proportional to the logarithmic of CCND1 concentration in the linear range from 40 fg/mL to 0.8 μg/mL with a detection limit of 15.8 fg/mL. Further, the good reproducibility, stability and selectivity of the as-prepared ECL immunosensor were also proved. Significantly, the anticancer effect of sophora frevescens on MCF-7 cells was investigated through quantitative analysis of overexpression of CCND1, which was related to proliferation of cancer cells. This research indicated the ECL immunosensor we suggested could offer great potential for the follow-up research in clinical diagnosis and anticancer drug screening.
研究领域:
生物医学工程
·
分析化学
·
材料科学
·
肿瘤学
✓ 已验证
产品关联
DOI
高影响因子
MINERALS ENGINEERING
·
2025
·
IF 5
Yunzhen Hu,Kangjing Wu,Shuai Wang,Zhanfang Cao,Xin Ma,Hong Zhong
The flotation separation of chalcopyrite (CuFeS 2 ) and molybdenite (MoS 2 ) is hindered by similar surface properties, typically requiring environmentally detrimental high-alkalinity conditions (pH > 10.0). Herein, we introduce 3,4,5-Trihydroxy-N,N-bis(2-hydroxyethyl)benzamide (TBHB), a gallic acid-derived surfactant, as an efficient selective depressant for chalcopyrite under near-neutral conditions (pH 6.0–8.0). Notably, chalcopyrite recovery is reactivatable via pH adjustment (pH > 9.0). Micro-flotation tests demonstrated TBHB's high selectivity, achieving 91.81% molybdenite recovery while suppressing chalcopyrite recovery to 12.61% at pH 8.0, outperforming conventional depressants (e.g., sodium thioglycolate). Artificial mixed minerals flotation further confirmed TBHB's efficacy, with a dosage of 75 mg/L achieving Mo recovery exceeding 80%, Cu recovery below 20%. Mechanistic investigations revealed TBHB chemisorbs on the chalcopyrite surface via phenolic hydroxyl-Fe coordination, supported by high adsorption capacity (> 1.6 mg/m 2 ), reduced hydrophobicity, and FTIR/XPS analyses, which showed Fe–O bond formation and red-shifted C=O/benzene ring vibrations. Zeta potential measurements affirmed pH-dependent adsorption/desorption. DFT calculations confirmed spontaneous adsorption ( ΔE = −1.8206 eV) and short O–Fe bond (1.99 Å), verifying Fe-site affinity. Conversely, TBHB showed negligible adsorption on the molybdenite surface, with values below 0.4 mg/m 2 and a contact angle of approximately 70°, preserving its floatability. This work establishes TBHB as a sustainable alternative for Cu-Mo separation, eliminating high-alkalinity requirements while advancing green reagent design through integrated experimental and computational insights.
研究领域:
矿物加工工程
·
表面化学
·
环境友好技术
·
计算化学
·
资源回收
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Caiyun Wang,Zhiquan Yang,Shuai Li,Ying Wang,Hongguo Zhang
As a hot issue, the scientific and effective separation and extraction of heavy metal ions from complex industrial effluent deserves wide investigation. Copper is an important valuable heavy metal in industrial wastewater. Selective extraction of copper ion (Cu 2+ ) from effluent not only alleviates the shortage of resources, but also has economic and social benefits. In this study, we used capacitive deionization (CDI) to selectively extract Cu 2+ from electroplating wastewater using the bimetallic sulfide CuFeS 2 electrode. The CuFeS 2 electrode showed good Cu 2+ extraction performance and selectivity in a variety of cationic coexistence systems and real electroplating wastewater, indicating its potential for practical application. Specifically, the adsorption capacity of Cu 2+ was up to 208.3 mg/g in a 100 mg/L CuSO 4 solution. The CuFeS 2 electrode removed more than 90 % of Cu 2+ and had the highest partition coefficient (K d ) in a variety of cationic coexistence systems. The characterizations demonstrated that the excellent performance of CuFeS 2 electrode during the adsorption process was mainly due to the Faraday redox reaction. This work offers a novel approach and theoretical basis for extracting Cu 2+ from electroplating wastewater by capacitive deionization
研究领域:
环境科学
·
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING SCIENCE
·
2025
·
IF 4.3
Usman Farooq,Xudong Hu,Jingyi Shang,Shuang Li,Jun Long,Lin Wang,Xinhai Wang
The increasing presence of pharmaceutical contaminants, such as dipyrone (DIP), in water systems highlights the urgent need for innovative and sustainable remediation technologies. This study examined the degradation of DIP using a chalcopyrite (CP)-activated peracetic acid (PAA) system, highlighting its potential for the removal of pharmaceutical pollutants. Experimental and statistical parameter optimization suggested that approximately 85.5 % of DIP degradation and 60 % of mineralization were achieved with CP (4 g/L) and PAA (10 mM) at neutral pH. Scavenger and probe experiments confirmed the presence of hydroxyl radicals ( • OH) and alkyl radical species in the CP/PAA system, but •OH was the primary contributor to DIP degradation. The surface-active sites confirmed that heterogeneous Cu(I) exerted more significant influence than Fe (II) of CP, producing 4.21 and 2.35 mg/L, respectively. The presence of reductive sulfur species in the CP allowed the capture of additional protons, creating sulfur vacancies and further strengthening the cycling of Cu and Fe species. DFT analysis confirmed that the FeCuS 2 -Fe adsorption energy (−3.71 eV) and the HOMO-LUMO gap of FeCuS 2 -Fe (0.03 eV) were critical to produce radicals. The CP/PAA system is suitable for DIP degradation and contributes significantly to the degradation of other environmental pollutants. It retained its capacity to degrade above 65 % for up to five consecutive cycles, offering a new and innovative method for water treatment.
研究领域:
环境科学
·
化学工程
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
Nanoscale
·
2017
·Vol. 9
·期 43
·16937-16949
·
IF 7.367
Binbin Ding,Chang Yu,Chunxia Li,Xiaoran Deng,Jianxun Ding,Ziyong Cheng,Bengang Xing,Ping'an Ma,Jun Lin
Photothermal therapy (PTT) has attracted considerable attention in cancer treatment. Herein, the facile synthesis of copper iron sulfide (chalcopyrite, CuFeS2) nanoplates (NPs) with well-defined shape was achieved by a template-mediated method. Chitosan (CS), a linear cationic polysaccharide, was used to improve the physiological stability and biocompatibility. CuFeS2 NPs with strong near-infrared (NIR) absorbance enabled contrasts in photothermal and photoacoustic (PA) imaging. In vitro and in vivo tumor ablation studies further demonstrated that CS-functionalized CuFeS2 (CuFeS2-CS) NPs could convert 808 nm NIR light into heat for PTT with a photothermal conversion efficiency up to 30.5%, which was clearly higher than that of CuS NPs (only 21.4%). Furthermore, CuFeS2-CS NPs could also load cis-platinum pro-drug (CuFeS2-CS-Pt), and CuFeS2-CS-Pt showed a better synergistic therapeutic effect with respect to either chemotherapy or PTT.
研究领域:
肿瘤学
·
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2021
·
IF 10.588
Yangzi Shangguan,Renji Zheng,Qiuyue Ge,Xuezhen Feng,Ranhao Wang,Yuanhao Zhou,Siyuan Luo,Lele Duan,Jia Lin,Hong Chen
Configuring reactive and stable catalytic interfaces is crucial to design efficient photocatalysts for Cr(VI) reduction. Herein, via the platinum decoration approach based on interfacial engineering , we developed an effective catalytic interface within novel semiconducting chalcopyrite quantum dots (Pt/CuFeS 2 QDs). Benefiting from the catalytic merits of the Pt modulated interfacial structure and electronic structure, Pt/CuFeS 2 QDs show a broader light absorption capability extending to near-infrared radiation (NIR) range with superior carriers separation performance and faster charge transfer efficiency, which delivers a three-folder faster photocatalytic Cr(VI) reduction efficiency comparing to the original CuFeS 2 QDs. Density functional theory (DFT) calculations unravel that Pt atoms prefer to be anchored with the surface S atoms to form a stable interfacial structure with faster electron transfer and Cr(VI) reduction dynamics. This work demonstrates that platinum decoration based on interfacial engineering is an effective strategy to simultaneously modulate the band structure and accelerate the interfacial reaction dynamics for semiconductor photocatalysts, which paves the way for designing highly efficient photocatalysts for light-driven environmental and energy engineering applications.
研究领域:
材料科学
·
环境科学
·
纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MINERALS ENGINEERING
·
2026
·
IF 6
Wentao Li,Hongxiang Xu,Erfeng Zhang,Zechao Huangfu,Jiushuai Deng
Copper site differences determine CuFeS 2 –MoS 2 flotation selectivity in Cu 2+ -containing systems. • ADT forms chelate coordination with surface Cu sites but not lattice Cu sites. • Monodentate ligands provide better CuFeS 2 –MoS 2 separation than bidentate ligands in Cu 2+ -containing systems. Interfaces involving Cu 2+ solutions play a critical role in CuFeS 2 -MoS 2 separation, and the differences among copper sites at the atomic scale are essential for understanding and controlling their separation in Cu 2+ -containing systems. Herein, sodium thioglycolate (STC) and amidinothiourea (ADT) were selected to systematically investigate the effects of copper site differences and inhibitor coordination modes on the selective separation of CuFeS 2 and MoS 2 in Cu 2+ -containing systems. The results suggest that the copper sites within the crystal lattice may be unable to form chelate rings with ADT, possibly due to geometric constraints imposed by the lattice coordination environment. In contrast, coordinated copper sites on the surface of CuFeS 2 may form chelate rings with ADT, thereby enhancing the inhibitory effect. The coordinated copper sites on the surface of MoS 2 may also exhibit a strong affinity for ADT, which hinders the selective separation of CuFeS 2 and MoS 2 . In comparison, STC exhibited a relatively weaker inhibitory effect on MoS 2 . Therefore, selecting reagents with appropriate structures may mitigate the adverse effects of Cu 2+ to some extent. These results suggest that monodentate ligand-based inhibitors containing multiple polar functional groups could be promising candidates for CuFeS 2 -MoS 2 separation in Cu 2+ systems. In addition, since Cu 2+ adsorbs more strongly to the surface of CuFeS 2 than to MoS 2 , and in combination with the control of Cu 2+ concentration, it is expected that the interference from Cu 2+ can be further reduced. This study provides new insights into the selection and design of MoS 2 -CuFeS 2 separation inhibitors in Cu 2+ -containing systems. Download: Download high-res image (300KB) Download: Download full-size image
✓ 已验证
产品关联
DOI
高影响因子
ChemistrySelect
·
2026
·Vol. 11
·期 23
·e73668
·
IF 2.3
Md Ibrahim Khalil,Camara Sidiki,Mainul Morshed,Huang Liang,Xinxin Zhang,Hongchao Ma
A well-structured magnetic CuFeS 2 /ZIF-67 hybrid catalyst was synthesized by embedding CuFeS 2 nanoparticles into a ZIF-67 framework for efficient peroxymonosulfate (PMS) activation and ultrafast dye degradation. The redox-rich Cu─Fe─Co interface promotes rapid electron transfer and continuous PMS activation, resulting in outstanding catalytic performance. Under optimized conditions (catalyst 75 mg L − 1 , PMS 125 mg L − 1 , dye 80 mg L − 1 , pH 6.4, and 20°C), the optimized 0.4-CuFeS 2 /ZIF-67 composite achieved 98.06% removal of Reactive Brilliant Blue KN-R (anthraquinone-based anionic reactive dye) within 0.5 min, following pseudo-first-order kinetics with a high rate constant (k obs = 7.49 min − 1 ). Electron paramagnetic resonance and quenching experiments confirmed the coexistence of radical species (SO 4 • − , •OH, and O 2 • − ) and a non-radical pathway involving 1 O 2 , with singlet oxygen identified as the dominant oxidant. The enhanced activity originates from the synergistic Cu + /Cu 2 + , Fe 2 + /Fe 3 + , and Co 2 + /Co 3 + redox cycling, while sulfur species (S 2 − /S 2 2 − ) act as electron mediators that promote charge transfer and stabilize active sites during PMS activation. The catalyst retained over 83% activity after repeated cycles with negligible metal leaching (Cu 0.010 mg L − 1 , Fe 0.033 mg L − 1 , Co 0.09 mg L − 1 ). Significant total organic carbon removal (52.81%) demonstrates effective mineralization, highlighting its potential for sustainable wastewater treatment applications. Graphical A magnetic CuFeS 2 /ZIF-67 hybrid catalyst enables ultrafast peroxymonosulfate activation through synergistic Cu─Fe─Co interfacial redox cycling and rapid electron transfer. Dominant singlet oxygen and radical pathways achieve rapid dye degradation, substantial mineralization, excellent recyclability, and low metal leaching, demonstrating strong potential for sustainable wastewater remediation under mild operating conditions.
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）