SEPARATION AND PURIFICATION TECHNOLOGY
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2022
·
IF 9.136
Tong Wang,Qing Guo,Hua Yang,Wen Gao,Ping Li
In this study, we developed an efficient and green pH-controlled reversible deep-eutectic solvents (DESs) based enzyme system for efficient extraction, transformation and in-situ separation of natural products from herbs. As a case study, seven isoflavones in the root of Pueraria lobata were selected as target compounds. A series of DESs were firstly prepared and the extraction efficiency for target compounds with or without cellulase catalysis was investigated. We found that [N 4444 ][Cl]:ethylene glycol (1:2) with cellulase addition show the highest extraction efficiency for isoflavones. More importantly, the phase behavior of [N 4444 ][Cl]:ethylene glycol (1:2) based cellulase system was found to be pH-controlled. When pH is 5.0, the system is a homogeneous single-phase system, which is conducive to the extraction of natural products. When pH is 6.4, the system changes from the single-phase to the heterogeneous two-phase, to realize the in-situ separation of the compounds. Therefore, by adjusting the pH of the system, the in-situ separation of isoflavones was successfully realized with high recovery yields. The pH-controlled DESs based enzyme-assisted extraction system overcomes the incompatibility between enzyme catalysis and conventional organic solvent in extraction, which could efficiently extract seven isoflavones from Pueraria lobata root.
研究领域:
绿色化学
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药学
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生物技术
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产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2020
·
IF 3.594
Juan-Yan An,Li-Tao Wang,Mu-Jie Lv,Jian-Dong Wang,Zi-Hui Cai,Yan-Qiu Wang,Su Zhang,Qing Yang,Yu-Jie Fu
Chestnut shells in large amounts are significantly underutilized agricultural and forestry waste that can be exploited as a resource for the production of high-valued nature active compounds. In this study, an efficient and green approach was established to extract and recover the highly valued phenolic compound, ellagic acid, from waste chestnut shells with choline chloride-based deep eutectic solvents (DESs). By utilizing optimized ultrasonic-assisted extraction conditions with choline chloride/n-propanol DES, solid–liquid ratio of 40 mg/mL, extraction time of 70 min and extraction power of 200 W, highly efficient extraction value for ellagic acid of 4.64 mg/g was obtained. Meanwhile, ellagic acid was recovered easily with a recovery percentage of 94.9% by anti-solvent precipitation method through the denaturation of DES with water. The purity of ellagic acid in the extracts reached 85.6%, which is more than two times to that via ethanol extraction methods (36.4%). In addition, the recovered ellagic acid exhibited strong antioxidant activity with IC 50 (0.309 mg/mL) and significant antibacterial activity with Minimal inhibitory concentration (MIC) (250 mm) and diameter of inhibition zone (DIZ) (17.60 μg/mL). The anti-solvent precipitation method could denature DES, led to higher extraction and recovery efficiency and high-purity ellagic acid simultaneously in one step. The novel method is of great significance to the whole chestnut production process for the utilization of waste chestnut shells. Furthermore, this method can also be used as a green, pollution-free alternative method for the extraction and recovery of phenolic components from natural resources for pharmaceutical and biochemical applications.
研究领域:
食品科学
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药物化学
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环境科学
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产品关联
DOI
高影响因子
FUEL
·
2016
·
IF 3.611
Chun-feng Mao,Rong-xiang Zhao,Xiu-ping Li
A series of Brønsted-Lewis acidic deep eutectic solvents (DESs) of C 9 H 10 O 2 ·XZnCl 2 (X from 0.5 to 3) were synthesized by simple mixing. The DESs were characterized by infrared spectroscopy, electrospray ionization mass spectrometry, and thermogravimetric analysis. The desulfurization of a model oil was investigated using C 9 H 10 O 2 ·XZnCl 2 as the extraction agent and catalyst, and H 2 O 2 as the oxidant. The effects of the molar ratio of phenylpropanoic acid to zinc chloride, reaction temperature, oxygen to sulfur (O/S) molar ratio, and volume ratio of DESs to oil on the desulfurization rate were investigated. The optimal conditions for desulfurization were determined to be a phenylpropanoic acid to zinc chloride ratio of 2:1, a reaction temperature of 50 °C, an O/S ratio of 6, a DESs to oil volume ratio of 0.25:1, and a model oil dosage of 5 mL. Under the optimal conditions, a desulfurization rate of 99.23% in 80 min was achieved. The recyclability of the DESs was also investigated, and the results showed that the desulfurization rate decreased slightly after five runs. These results demonstrate that C 9 H 10 O 2 ·0.5ZnCl 2 DESs exhibit high desulfurization activity and stability in extraction and oxidation desulfurization systems.
研究领域:
化学工程
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环境科学
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DOI
高影响因子
INTERNATIONAL JOURNAL OF THERMAL SCIENCES
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2025
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IF 5
Xiao Zhang,Long Geng,Kaifeng Luo,Wenbo Huang,Jiateng Zhao,Changhui Liu
Investigating the relationship between molecular interactions and thermophysical properties offers valuable insights into the development of advanced heat transfer fluids. In this work, glycerol-calcium chloride-based deep eutectic solvents (DES) were systematically examined through quantum chemical calculations and experimental methods to reveal their unique molecular mechanisms and thermal performance. Strong hydrogen bonding and coordination interactions were identified as critical factors enhancing the stability of the DES system, at the B3LYP-D3/6-31G(d, p) theoretical level, the calculated binding energy of DES reaches −223.94 kJ/mol, significantly lower than that of pure glycerol (−61.62 kJ/mol), indicating stronger and more stable interactions. Experimentally, the DES exhibited exceptional thermal stability, retaining structural integrity below 200 °C, while its boiling point increased by 4–5 °C and freezing point decreased by 4–6 °C compared to glycerol. Additionally, at an 8:1 glycerol-calcium chloride molar ratio, the specific heat capacity was approximately 1.5 % higher at 80 °C, demonstrating superior thermal storage capacity. These findings highlight the potential of DES as environmentally friendly and high-performance alternatives for industrial heat transfer and energy storage applications.
研究领域:
化学工程
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材料科学
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热能工程
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
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2023
·
IF 8.8
Hongchen Wan,Zhiwei Zhu,Da-Wen Sun
To develop a novel active packaging for fruit preservation, two different deep eutectic solvents (DESs) comprising choline chloride, betaine and glycerol [ChCl:Gly (1:2) and Be:Gly (1:2)] were prepared and the corresponding DESs-based films (DES@Gel) using gelatin as polymer matrix were fabricated. DES@Gel showed smoother morphologies and better optical and mechanical properties as compared with Gel. Moisture sorption isotherm curves, the enhancement of water vapour permeability (WVP) and the excellent moisture absorption–desorption cyclist performance illustrated the moisture regulation hypothesis mechanism of DES@Gel. Furthermore, cherry tomato preservation experiment was carried out and the groups treated with DES@Gel showed better performances. The moisture regulation property of DES@Gel could broaden new avenues for active packaging.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Foods
·
2023
·Vol. 12
·期 18
·3438
·
IF 5.2
Chaoqun Sun,Guodong Wang,Jing Sun,Jiyong Yin,Jian Huang,Zizi Li,Di Mu,Menglu He,Tingting Liu,Jiali Cheng,Hanchen Du,Yan Chen,Wenjie Qu
Polygonatum sibiricumPolysaccharide (PsP) with antioxidant function is the main active component ofPolygonatum sibiricum(P.sibiricum). The currently poor extraction yield and extraction methods of PsP cannot meet the application of that in food industrial production. In this research, an ultrasound-assisted extraction-deep eutectic solvents (UAE-DESs) method, which has never been used in the PsP industry, was first used to extract PsP. The extraction conditions were optimized by the response surface method (RSM). Both the extraction yield and antioxidant function were simultaneously considered during the optimization process. The indicators of PsP’s level and antioxidant activity in vitro were used to present the extraction yield of the UAE-DESs method, the purity, and the antioxidant effect of PsP. Under the optimal conditions, which included a liquid–solid ratio of 26:1 (mL:g), extraction temperature of 80 °C, ultrasonic time of 51 min, and ultrasonic power of 82 W, the PsP extraction yield could reach (43.61 ± 0.09)%, which was obviously higher than single DESs (33.81%) and UAE (5.83%), respectively, and the PsP appeared favorably antioxidant function. This research proposed an efficient extraction method for PsP, filled the basic research gap, and further improved the development of PsP as a dietary supplement with antioxidant function in the food industry.Keywords:Polygonatum sibiricumPolysaccharide (PsP);ultrasound-assisted extraction-deep eutectic solvents (UAE-DESS);antioxidant function;response surface method (RSM)
研究领域:
食品科学
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药学
·
生物技术
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产品关联
DOI
PubMed
高影响因子
INDUSTRIAL CROPS AND PRODUCTS
·
2017
·
IF 3.181
Miao Zuo,Kai Le,Yunchao Feng,Caixia Xiong,Zheng Li,Xianhai Zeng,Xing Tang,Yong Sun,Lu Lin
In this study, we put forward an effective two-step method of producing biofuel 5-ethoxymethylfurfural (5-EMF) from carbohydrates with DES mixture. With the catalysis of Amberlyst-15, 77.3% and 65.2% yield of 5-EMF were obtained respectively from the fructose and inulin in mild conditions. In addition, CrCl 3 modified Amberlyst-15 showed excellent catalytic performance in the aldoses dehydration, 46.7% and 50.2% of 5-EMF yield could be obtained from glucose and sucrose in the two-step reactions. Moreover, all catalysts used in this study could be effectively reused for several times.
研究领域:
生物化学
·
可再生资源与环境科学
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产品关联
DOI
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
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2020
·
IF 6.551
Haoran Song,Yuwei Wang,Zheng Ling,Daoyuan Zu,Zhuo Li,Yongming Shen,Changping Li
In-situ construction of heterojunction photocatalyst on two-dimensional (2D) Ti 3 C 2 MXene substrate has been proved to be a feasible method to enhance the photocatalytic degradation of organic pollutants. However, the limited interlayer spacing of 2D Ti 3 C 2 hinders the in-situ growth of TiO 2 photocatalyst. Herein, the intercalation strategy was developed in deep eutectic solvents (DESs) method to achieve interlayer expansion of Ti 3 C 2 and improve Ti 3 C 2 -derived photocatalyst performance. Because of the intercalation of choline cations, the DESs method synthesized Ti 3 C 2 (Ti 3 C 2 -DES) had the larger c -lattice parameter than that of traditional HF method synthesized Ti 3 C 2 (Ti 3 C 2 -HF). The interlayer space of Ti 3 C 2 -DES could be intercalated with more water molecule for oxidization of the Ti atoms, which remarkably promoted the in-situ growth of TiO 2 crystals. The formed heterojunction between (001) and (101) facets enhanced carriers separation. The Ti 3 C 2 substrate with excellent conductivity further promoted carriers transfer. As a result, Ti 3 C 2 /TiO 2 photocatalyst exhibited superior perfluorooctanoic acid (PFOA) removal performance (almost 100% removal efficiency and 49% defluorination efficiency within 16 h) compared with the traditional Ti 3 C 2 -HF/TiO 2 (22% removal efficiency and 12% defluorination efficiency within 16 h). This study provides a feasible strategy for enhancing photocatalytic degradation of PFOA by Ti 3 C 2 MXene-derived heterojunction photocatalyst.
研究领域:
材料科学
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环境科学
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化学工程
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产品关联
DOI
PubMed
高影响因子
INDUSTRIAL CROPS AND PRODUCTS
·
2023
·
IF 5.9
Min Zhou,Meiqi Lv,Sulin Cai,Xingjun Tian
DESs are promising green solvents in lignocellulose pretreatment . In this work, four choline chloride based DESs were synthesized and their physicochemical properties were evaluated. Herbaceous lignocellulose (wheat straw, sorghum straw) and woody lignocellulose biomass (poplar wood, pine wood) were selected as pretreated substrates. In order to reveal the mechanism that pretreatment can improve the efficiency of enzymatic hydrolysis , the pretreated lignocellulose and lignin were analyzed. SEM , FT-IR and XRD characterization revealed the microstructural changes of pretreated lignocellulose, including the increase of surface roughness and pore erosion, changes of polysaccharide/lignin chemical groups, the increase of CrI. The efficient delignification increased the accessibility of enzyme to cellulose , the lignin content negatively affected enzymatic hydrolysis conversion. Furthermore, GPC analysis showed that the polydispersity of sulfonated lignin was reduced after pretreatment, lignin had more homogeneous molecular structures. The degree of unsaturation was calculated according to the elemental composition of sorghum straw and lignin. The unsaturation of pretreated sorghum straw decreased, that may be due to the removal of partial lignin. The elemental composition of acid insoluble lignin (separated from sorghum straw) reflects the increase of unsaturation of lignin after pretreatment.
研究领域:
生物化学
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环境科学
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产品关联
DOI
高影响因子
Green Processing and Synthesis
·
2019
·Vol. 8
·期 1
·568-576
·
IF 1.128
Yingna Cui,Changping Li,Ming Bao
Deep eutectic solvents (DESs) are successfully used as powerful and recyclable catalysts and solvents for the synthesis of 3,4-dihydropyrimidin-2(1 H )-ones/thiones (DHPMs). The acidity of DESs is the main factor that determines catalytic activity. DESs, based on p -toluene sulfonic acid (PTSA) and choline chloride (ChCl), exhibits the highest catalytic activity. ChCl/2PTSA is suitable for a vast variety of aromatic aldehydes with electron-donating and electron-withdrawing groups, different β-diketonates, and urea or thiourea to obtain the corresponding DHPMs. Furthermore, DESs can be recycled easily after synthesis. The reused DESs achieve catalytic efficiency six times without significant changes. This study will provide a new green catalyst and efficient process for the synthesis of DHPMs.
研究领域:
有机化学
·
绿色化学
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DOI
高影响因子
BIORESOURCE TECHNOLOGY
·
2017
·
IF 5.651
Xue-Dan Hou,Ao-Lin Li,Kai-Peng Lin,Yuan-Yuan Wang,Zhi-Yin Kuang,Shi-Lin Cao
Rice straw pretreatment mediated by choline chloride (ChCl) or lactic acid (Lac) sequences deep eutectic solvents (DESs) was investigated in this work. Hydrogen bond acceptors (HBAs) and hydrogen bond donors (HBDs) proved to be both important for DESs pretreatment efficiency. DESs containing lots of hydroxyl or amino groups with a high intermolecular hydrogen-bond (H-bond) strength exhibited weak biomass deconstruction abilities. The presence of strong electron-withdrawing groups in DESs was benefit for xylan removal, thus furnishing higher cellulose digestibility. The relationships between the properties of DESs, xylan removal and cellulose digestibility of pretreated biomass were established. It was found that xylan removal was negatively correlated with the pKa values of HBDs, and the enzymatic cellulose digestibility of the residues was linearly and positively related to xylan removal instead of delignification. These results provide a preliminary reference for rational design of novel DESs for biomass pretreatment.
研究领域:
化学工程
·
生物质加工
·
可持续化学
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产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2016
·
IF 5.31
Hongying Lü,Pengcheng Li,Yongming Liu,Lingwan Hao,Wanzhong Ren,Wenjiao Zhu,Changliang Deng,Feng Yang
A novel hybrid Anderson-type polyoxometalate, {[(CH 3 ) 3 N(CH 2 ) 2 OH] 2 }[H 0.2 K 0.2 Na 2.6 (H 2 O) 6 ][IMo 6 O 24 ] (Abbreviated as (ChO) 2 K 0.2 Na 2.6 IMo 6 ) was synthesized in a deep eutectic solvent and characterized by XRD, FT-IR, thermal analysis, electrochemical measurements and inductively-coupled plasma, atomic emission spectrometer (ICP-AES). This hybrid polyoxometalate was used as a catalyst in ionic liquids (ILs) for desulfurization of model diesel. The catalyst (ChO) 2 K 0.2 Na 2.6 IMo 6 in the extraction and catalytic oxidative desulfurization (ECODS) system, containing H 2 O 2 and 1-octyl-3-methylimidazolium tetrafluoroborate (OmimBF 4 ), displayed so high activity that the removal of DBT can reach 100% at 60 °C in 60 min. Sulfur removal for S-compounds was in the following order: DBT > 4,6-DMDBT > BT. The desulfurization system shows so good stability that it can be recycled 20 times without noticeable decrease in activity.
研究领域:
化学
·
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）