DALTON TRANSACTIONS
·
2019
·Vol. 48
·期 12
·4015-4025
·
IF 4.052
Haiyu Wang,Zhiliang Jin,Xuqiang Hao
The development of a highly active and stable non-noble-metal hydrogen-producing catalyst for renewable energy reserves and conversion remains a serious challenge. In this work, we described a novel binary solution (DETA/H2O) reaction for preparing a composite catalyst composed of CdS nanoparticles grown on CoSe2 nanobelts. The composite catalyst (CoSe2/CdSDETA) exhibits excellent catalytic activity for a hydrogen evolution reaction in an EY sensitized 15% (v/v) TEOA aqueous solution under visible light irradiation (λ ≥ 420 nm). Moreover, the catalytic activity of the P-doped sample (CoSe2/CdSDETA|P) was further improved. The excellent performance is ascribed to the synergy among DETA and atomic-level P-doping. Some essential characterization methods such as XRD, SEM, TEM, UV-vis diffuse spectroscopy, XPS, photoelectrochemistry, PL, etc. were carried out to support the related results and a possible reaction mechanism was put forward.
研究领域:
材料科学
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能源化学
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产品关联
DOI
PubMed
高影响因子
FUEL
·
2024
·
IF 6.7
Jiaxi Yang,Dan Gao,Heng Zhang,Qun Yi
The efficient capture of carbon dioxide (CO 2 ) by porous ionic liquids (PILs) has become one of the important ways to deal with the greenhouse effect and enhance environmental protection. In order to enhance the CO 2 capture efficiency of PILs, 2 amino-functional ionic liquids (ILs) were synthesized in deionized water: tetraethylenepentamine-2-methylimidazole ([TEPA][MIm]) and diethylenetriamine-2-methylimidazole ([DETA][MIm]). 2 zeolite imidazolidin-8 frames (ZIF-8-W and ZIF-8-M) were prepared in methanol and deionized water. The performance of the material was verified through FT-IR infrared spectroscopy, TGA-DTG curves, XRD spectra, adsorption desorption curves, and corrosive changes. Based on this, the porous ionic liquid ZIF-8-W/[TEPA][MIm] with the best performance and ZIF-8-W with the best environmental friendliness were successfully constructed. The chemical reaction mechanism of CO 2 in PILs were explored. The results showed that the thermogravimetric temperature of all materials was greater than 370 K, and the difference in adsorption capacity between ZIF-8-W and ZIF-8-M was only about 36.3 ml/g, the maximum mass change rates of the two ILs after immersion in ceramic and stainless steel tubes for 7 days were only 0.78 % and 0.29 %, respectively. On the premise of ensuring fluidity, the maximum capture capacity of ZIF-8-W/[TEPA][MIm] for pure CO 2 reached 2.22 mol/mol PILs, and the maximum capture capacity for CO 2 in artificial flue gas reached 2.03 mol/mol PILs, which was 21.9 % and 31.6 % higher than the maximum capture capacity of pure ionic liquids, respectively. When [TEPA][MIm] in PILs reacts with CO 2 , it conforms to the characteristics of “zwitterions”.
研究领域:
材料科学
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环境科学
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Yining Wang,Chikezie Nwaoha,Teerawat Sema,Bin Liu,Zhiwu Liang,Paitoon Tontiwachwuthikul,Jin-Heng Li
The development of efficient and low-energy solvents is critical for improving the performance and economic viability of post-combustion carbon capture processes. Conventional aqueous amine systems often suffer from high regeneration energy and limited CO 2 absorption capacity. To address these limitations, this study investigated a phase-change solvent system based on diethylenetriamine (DETA), alcohols, and water, aiming to enhance absorption performance and reduce energy consumption. Five alcohols with varied physicochemical properties-1-propanol, 1-butanol, 1-pentanol, 3-methoxypropanol, and 3-phenylpropanol were evaluated as partial water replacements to promote liquid-liquid phase separation and improve CO 2 uptake. The results show that 1-pentanol produced the highest CO 2 loading due to its stronger hydrophobicity and effective phase-separation behavior. A DETA/1-pentanol/water mass ratio of 3:4:3 achieved optimal performance, yielding a CO 2 loading of 2.417 mol/mol at 313 K. Kinetic and equilibrium studies indicated that 313 K is the preferred absorption temperature, while 353 K provides optimal desorption performance with a cycle capacity of 0.613 mol/mol and energy consumption of 2230.2 kJ. Compared to benchmark solvents such as 5 M MEA, the DETA/1-pentanol/water system demonstrated superior CO 2 absorption capacity and lower regeneration energy. These findings suggest that phase-change solvents incorporating amphiphilic alcohols offer a promising strategy for enhancing carbon capture efficiency while mitigating energy demands.
研究领域:
化学工程
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环境科学
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能源技术
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材料科学
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产品关联
DOI
高影响因子
DIAMOND AND RELATED MATERIALS
·
2026
·
IF 5.1
Shifeng Ji,Zhuo Li,Yunqing Xing,Nan Yao,Yingjie Zhang,Changbing Ye,Guohua Wang,Maogang Hu,Chunmei Gao
Heterojunction-structured graphitic carbon nitride@bismuth oxyiodide (g-C 3 N 4 @BiOI) nanocomposites were successfully synthesized via a facile solvothermal method. The as-prepared composites were characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM), and UV–visible diffuse reflectance spectroscopy (UV–vis DRS) to elucidate their microstructure, chemical composition, and optical properties. Subsequently, a highly efficient UV/g-C₃N₄@BiOI/H₂O₂ photocatalytic system was developed for the rapid degradation of diethylenetriamine (DETA). Under optimal conditions (initial pH 10.3, 0.4 mL/L H₂O₂, and 0.06 g/L 50 wt% g-C₃N₄@BiOI), the system achieved 95% DETA removal within 30 min under UV irradiation. Notably, cyclic degradation tests coupled with post-characterization revealed the exceptional stability and reusability of the g-C₃N₄@BiOI nanocomposite. Mechanistic studies through radical quenching experiments and electron paramagnetic resonance (EPR) spectroscopy confirmed •OH as the primary reactive species. Furthermore, the degradation pathways were elucidated by combining Gaussian 09 W theoretical calculations with gas chromatography–mass spectrometry (GC–MS) analysis. Finally, the toxicity evaluation model was established by toxicity evaluation software, and the experiments of mung bean germination and zebra fish egg incubation verified the effective detoxification of DETA solution after photocatalytic treatment.
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DOI
高影响因子
Anti-Cancer Agents in Medicinal Chemistry
·
2024
·Vol. 24
·期 15
·1142-1150
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IF 2.6
Wang Mingdong,Yin Jizhong,Han Qianyu,Li Bing,Zhao Xue-Wei,Xue Lei
Background: Non-Small Cell Lung Cancer (NSCLC) ranks as a leading cause of cancer-related mortality, necessitating the urgent search for cost-effective and efficient anti-NSCLC drugs. Our preliminary research has demonstrated that arsenic trioxide (ATO) significantly inhibits NSCLC
angiogenesis, exerting anti-tumor effects. In conjunction with existing literature reports, the Nrf2-IL-33 pathway is emerging as a novel mechanism in NSCLC angiogenesis. Objective: This study aimed to elucidate whether ATO can inhibit NSCLC angiogenesis through the Nrf2-IL-33 pathway.
Methods: Immunohistochemistry was employed to assess the expression of Nrf2, IL-33, and CD31 in tumor tissues from patients with NSCLC. DETA-NONOate was used as a nitric oxide (NO) donor to mimic high levels of NO in the tumor microenvironment. Western blot, quantitative real-time PCR,
and enzyme-linked immunosorbent assay were utilized to evaluate the expression of Nrf2 and IL-33 in the NCI-H1299 cell line. Subcutaneous xenograft models were established in nude mice by implanting NCI-H1299 cells to assess the anti-tumor efficacy of ATO. Results: High expression levels
of Nrf2 and IL-33 were observed in tumor samples from patients with NSCLC, and Nrf2 expression positively correlated with microvascular density in NSCLC. In vitro, NO (released from 1mM DETA-NONOate) promoted activation of the Nrf2-IL-33 signaling pathway in NCI-H1299 cells, which was
reversed by ATO. Additionally, both Nrf2 deficiency and ATO treatment significantly attenuated NOinduced IL-33 expression. In vivo, both ATO and the Nrf2 inhibitor ML385 demonstrated significant inhibitory effects on angiogenesis tumor growth. Conclusion: Nrf2-IL-33 signaling is
usually activated in NSCLC and positively correlates with tumor angiogenesis. ATO effectively disrupts the activation of the Nrf2-IL-33 pathway in NSCLC and thus inhibits angiogenesis, suggesting its potential as an anti-angiogenic agent for use in the treatment of NSCLC.
研究领域:
肿瘤学
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药理学
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分子生物学
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细胞生物学
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DOI
PubMed
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2018
·Vol. 25
·期 14
·13645-13659
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IF 2.8
Liu Yunjie,Ren Dezhang,Song Zhiyuan,Wan Xinyan,Zhang Chuntao,Jin Fangming,Huo Zhibao
A novel magnetic heavy metal adsorbent was prepared via diethylenetriamine (DETA) modification on magnetic hydrothermal carbon, with glucose and sugar-containing waste water as the carbon source. The prepared materials were characterized by FT-IR, SEM, TEM, EDXRF, TGA, elemental analysis, XPS, and magnetic moment determination. In this paper, the adsorption mechanism of the modified and unmodified adsorbents was well discussed. Four kinds of waste water (watermelon juice, expired sprite, sugar-pressing waste water, and confectionary waste water) were employed to produce heavy metal ion adsorbents; the chemical properties of hydrothermal carbon derived from the proposed sources were analyzed as well. The maximum uptake capacity for Cu 2+ , Pb 2+ , and Cd 2+ of the adsorbent produced from glucose was 26.88, 103.09, and 25.38 mg g −1 , respectively. After 5 cycles, the adsorption ability was still well preserved. This work represents an efficient new direction for the treatment of heavy metal ions in water and the reuse of sugar-containing waste water.
The schemetic of DETA-modified magnetic carbon preparing from sugar-containing wastewater
研究领域:
环境科学
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材料科学
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产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2022
·
IF 9.136
Huixing Yang,Wei Li,Yangyang Jiang,Qiuming Wei,Linlin Hou,Zhiliang Wu,Qinyu He,Yinzhen Wang,Dingyuan Tang
The proper design of photocatalysts is essential to improving photocatalytic decomposition of water and degradation of pollutants. In this work, we used nitrogen-rich carbon nitride with high electronic properties combined with CdS-DETA to generate CdS-DETA@g-C 3 N 5 composite, and diethylenetriamine (DETA) was used to enhance the band bending to enable the excellent photocatalytic performance of the photocatalyst. The hydrogen evolution rate (14.23 mmol/(g·h)) of the CdS-DETA@g-C 3 N 5 composite is 7.1, 7.5, and 4.5 times higher than that of g-C 3 N 5 (2.03 mmol/(g·h)), 20CSCN5 (1.89 mmol/(g·h)), and CdS-DETA (3.17 mmol/(g·h)), and the OFLX degradation rate (95.6 %) is 3.4 and 1.5 times higher than that of g-C 3 N 5 and CdS-DETA, respectively. These performance enhancements result from the enhancement of energy band bending, the construction of a built-in electric field (IEF), and the retention of high redox carriers. This work provides new insights into the design of nitrogen-rich carbon nitride-based photocatalyst for efficient photocatalytic degradation and hydrogen precipitation activity.
研究领域:
材料科学
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环境科学
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化学工程
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
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IF 7.7
Ding Wang,Yaoqing Chu,Shuiping Liu,Lianjiang Tan
Vessel normalization has proved imperative in tumor growth inhibition. In this work, biopolymer-based hybrid nanospheres capable of normalizing blood vessels were designed to improve the therapeutic effect of chemotherapeutic drugs. Zn 0.4 Fe 2.6 O 4 nanoparticles (ZFO NPs) were synthesized, and were encapsulated in cross-inked chitosan (CS) along with a nitric oxide (NO) precursor, DETA NONOate, forming hybrid ZFO/NO@CS nanospheres highly stable in physiological environment. The structure, morphology and size of the nanospheres were characterized. The ZFO/NO@CS nanospheres could release NO under acidic conditions typical of intratumoral and intracellular environment. The results of related factors expression, wound healing and tube formation assays demonstrated that both the encapsulated ZFO NPs and the released NO were able to inhibit angiogenesis in tumors. The ZFO/NO@CS nanospheres enhanced the antitumor efficacy of the chemotherapeutic drug DOX by normalizing tumor vessels, as evidenced by in vivo experiments for CT26 tumor-bearing mice. By analyzing the contents of Fe in the tumor and different organs, the nanospheres were found to accumulate primarily at the tumor site. The blood analysis showed little side effect of the nanospheres. The ZFO/NO@CS nanospheres have great potential in improving tumor therapeutic effect when used in combination with chemotherapeutic drugs.
研究领域:
纳米技术
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癌症研究
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药学
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生物医学工程
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DOI
PubMed
高影响因子
Biomaterials Research
·
2024
·
IF 8.1
Ding Wang,Cheng-Jie Qiu,Yaoqing Chu,Anzhuo Zhang,Ran Huang,Si-Jian Pan,Lianjiang Tan
Lung cancer remains a great threat to human health despite the rapid development of various therapeutic methods. Chemotherapy continues to be the most commonly employed treatment for lung cancer; however, it often suffers from low drug delivery efficiency and severe side effects. To enhance the therapeutic efficacy of chemotherapy, we developed a novel strategy that integrates tumor vasculature normalization with the co-delivery of therapeutic agents. This strategy employs a diblock polymeric vesicle with a reduction-sensitive linkage. Paclitaxel (PTX) is encapsulated in the bilayer, while an acid-sensitive nitric oxide (NO) precursor, DETA NONOate, and zinc oxide nanoparticles (ZnO NPs) are loaded into the central cavity. The resulting nanosystem, (ZnO,NONO)@Ves-PTX, is designed to release NO under the acidic conditions typical of the tumor microenvironment (TME) and intracellular environment. The released NO in the TME inhibits angiogenesis, thereby facilitating the delivery and distribution of therapeutic agents. Upon internalization by tumor cells, (ZnO,NONO)@Ves-PTX decomposes in response to intracellular glutathione (GSH), releasing the loaded agents. DETA NONOate and ZnO NPs generate NO and Zn2+ ions, respectively, at the intracellular pH, which synergistically inhibit tumor growth alongside PTX. This combined therapeutic approach demonstrated remarkable potential in improving the chemotherapeutic efficacy for lung cancer, offering a promising direction for future cancer treatments.
研究领域:
肿瘤学
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药理学
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纳米技术
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癌症治疗
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产品关联
DOI
PubMed
高影响因子
AUSTRALIAN JOURNAL OF CHEMISTRY
·
2025
·Vol. 78
·期 9
·NULL
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IF 0.9
Huipeng Zhao,Jingsi Yang,Heli Tian,Kunjie Li,Ruihong Zhao,Xiaoqing Liu,Pingxia Zhang,Xiaoxue Niu,Guicai Wu,Haoming Li
In this study, four DETA-SiO2 solid amine adsorbents were prepared by an impregnation method using diethylenetriamine (DETA) as the amine source and four types of silica with different pore structures as the carrier, and the effects of varying amine concentrations, temperatures and pressures on the CO2 adsorption performance were investigated. The results showed that the prepared N-MCM-48-C material reached a maximum CO2 adsorption of 417.45mgg−1 at 25°C and 0.5MPa. The effect of pressure on the adsorption performance was verified by kinetic calculations using the intraparticle diffusion model and the Thomas dynamic adsorption model. The presence of surfactant (CTAB) inside the carrier diluted the amine concentration, which improved the homogenisation of the amine on the carrier and increased the CO2 mass transfer efficiency and adsorption capacity. Multiple pressure swing adsorption (PSA) experiments have shown that N-MCM-48-C material has stable adsorption performance during the PSA process and the adsorption capacity can reach 300mgg−1.
研究领域:
环境科学
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材料化学
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化学工程
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碳捕集与封存（CCS）
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吸附技术
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产品关联
DOI
高影响因子
DYES AND PIGMENTS
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2025
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IF 4.2
Weilong Du,Jie Ren,Haonan Hu,Yan Zhao,Lei Cao,Dongjun Wang,Xiangkui Ren
In recent years, non-traditional intrinsic luminophores (NTILs) have garnered significant attention due to their ability to produce bright fluorescence after simple treatments. In this study, by employing a straightforward methodology of oxygen purging and controlled thermal treatment (40–120 °C), we demonstrated that non-traditional small-molecule amines (mainly diethylenetriamine, DETA) can exhibit rare dual fluorescence characteristics, including excitation-independent (EIF) and excitation-dependent (EDF) behaviors. More importantly, through structure characterization, fluorescence lifetime analysis, and simulation calculations, we confirmed the following structure-mechanism relationship underlying DETA luminescence: when pure DETA molecules were heated within the 40–80 °C, a stable dimeric structure (DETA-dimers) formed through hydrogen-bond interactions resulted in fluorescence centers exhibiting EIF characteristics. Notably, when the temperature increased further (80–120 °C), DETA-dimers in their excited state interact with oxygen molecules under external light, which formed dynamic excimers through space conjugation, denoted as [DETA-dimer … O 2 ], resulting in EDF phenomenon. Finally, capitalizing on DETA dual fluorescence properties, we successfully implemented EIF-based ion detection and EDF-enabled fluorescence staining applications. Consequently, this work advanced the mechanistic understanding of NTILs' intrinsic luminescence and established a framework for optimizing their performance in high-sensitivity fluorescence imaging and probe development.
研究领域:
材料科学
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物理化学
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有机化学
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荧光光谱学
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分析化学
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生物成像
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传感技术
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产品关联
DOI
高影响因子
Journal of Materials Chemistry B
·
2021
·Vol. 9
·期 13
·2998-3004
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IF 6.331
Jia An,Yongqin Hu,Guoyi Liu,Meizhu Chen,Rubing Chen,Ying Lyu,Mengdi Yuan,Mengfei Luo,Yufei Liu
Considering the limited sensitivity and accuracy of single-signal assay strategies, the multi-signal assay strategy has sparked significant excitement in recent years. In this study, for the first time, we reported a one-pot method in situ synthesis of carbon-containing nanoparticles (CNPs) via p-aminophenol (AP) and diethylenetriamine (DETA). The CNP solution exhibits yellow and light blue fluorescence under UV-light. Moreover, the CNPs exhibited excellent photoluminescence stability even under extreme conditions. Inspired by the alkaline phosphatase (ALP)-triggered specific catalytic reaction, we constructed an ultrasensitive fluorescence and colorimetric two-channel strategy for monitoring the ALP activity. By optimizing the detection parameters, the detection limits for both fluorometric and colorimetric were 0.05 mU mL−1. Moreover, the strategy showed high specificity and was successfully applied to monitor the ALP activity level in human serum samples. The analytical strategy opened a new window for the detection of the ALP activity, screening of the ALP inhibitor, and disease diagnosis.
研究领域:
分析化学
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生物传感器
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纳米技术
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医学诊断
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）