Journal of Bionic Engineering
·
2018
·Vol. 15
·期 3
·461-470
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IF 2.325
Xiong Xiong,Liu Yumei,Shi Feng,Zhang Guowei,Weng Jie,Qu Shuxin
The aim of this study is to investigate the effect of the contents of modified 3, 4-dihydroxyphenyl-L-alanine (DOPA), named as dopamine methacrylamide (DMA), on the adhesion of mussel-inspired adhesives in air and water. A series of adhesives, p(DMA-co-MEA), were synthesized by copolymerized DMA and methoxy ethylacrylate (MEA) with the content of DMA from 2 mol.% to 10 mol.%. Results of 1 H NMR show that the contents of DMA in all adhesives are near to the theory ratios of DMA in the staring reagents. Adhesives with more than 5 mol.% of DMA appear adhesion, while adhesives with 2 mol. % and 3 mol. % of DMA show almost no adhesion in air and water. Adhesive with 7 mol.% of DMA has the highest molecular weight and adhesion either in air or in water in all adhesives. Adhesion of adhesive is synergistically influenced by the content of DMA, molecular weight and elastic modulus of adhesive. It is because that higher content of DMA would provide more DOPA, which leads to the coordination bond between DOPA and metal ions. It is feasible to develop the mussel-inspired adhesive through incorporating DMA into polymers, which will have potential application in the clinic.
研究领域:
材料科学
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化学
·
生物医学工程
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DOI
高影响因子
ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Zhongshuai Gao,Shuya Zhang,Yanyi Duan,Heng Chang,Mei Cui,Renliang Huang,Rongxin Su
Marine biofouling and corrosion have become the main problems affecting the development of the marine industry. Silicone-based coatings have been widely used for antifouling and anticorrosion due to their low surface energy. However, the poor adhesion and low mechanical stability of these materials limit their application in complex marine environments. In this work, we presented a marine antifouling and anticorrosion coating named POSS-DMA@PDMS-TCM through photoinitiated thiol–ene click reaction combined with (mercaptopropyl) methylsiloxane dimethylsiloxane (PDMS-SH), dopamine methacrylamide (DMA), sulfhydryl-functionalized organosiloxanes (POSS-(SH)8), and N-(2,4,6-trichlorophenyl) maleimide (TCM). The POSS-DMA@PDMS-TCM coating exhibited strong stability and bonding ability both in air (2.17 MPa) and underwater (2.11 MPa) when the DMA content was 3 wt %. The high antibacterial (98.1% for Staphylococcus aureus and 99.5% for Escherichia coli) and antidiatom (94.5%) properties of the POSS-DMA@PDMS-TCM coatings have also been confirmed. Moreover, the POSS-DMA@PDMS-TCM coatings show excellent antifouling abilities in 120-day marine field tests, reducing fouling by 65.5% in comparison to the blank group. The coating also displayed superior anticorrosion performance with Ecorr values of −0.055 V, Icorr values of 7.67 × 10–6 , and Rp values of 3.10 × 105 Ω for Cu, which benefited from excellent chelating effect and liquid repellency. This study provides a novel strategy for the development of high-quality marine antifouling and anticorrosion coatings.
研究领域:
材料科学
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海洋工程
·
生物医学
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产品关联
DOI
PubMed
高影响因子
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
·
2018
·
IF 3.974
Bin Li,Bowen Gu,Zhaoguang Yang,Ting Zhang
Arsenic contamination of water is a global concern due to its heavy threat to human health. In this study, the submerged macrophyte Vallisneria natans (Lour.) Hara was used to remove environmentally relevant concentrations of arsenic in the binary As(III)/As(V) system. The concentrations of total arsenic (tAs) and As(III) in water dropped rapidly within 3 days, while As(V) first increased slightly within 3 days and then gradually decreased. About 1.2% dimethylarsinate (DMA) was detected at the 14th day of treatment. These findings indicated that As(III) could be oxidized to As(V) and methylated to DMA in water with V. natans . In relation to V. natans , both tAs and As(V) were much higher in roots compared to leaves. Arsenate was the predominant species (≥ 95.65 ± 0.10%) in roots, and As(III) was only found at the 14th day (3.45–6.96 mg kg –1 ). In leaves, As(III) significantly increased ( P < 0.05) as the treatment duration increased. The proportions of As(V) (27.99–40.03%) were lower than those of As(III) and arsenobetaine (AsB) was detected (0.52–1.87 mg kg –1 ) after 7 d. The results of arsenic speciation demonstrated that the transformation of arsenic species in V. natans included As(V) reduction and As(III) methylation to AsB. There were a decrease in chlorophyll content, and an increase in MDA level and antioxidant enzymes (SOD, CAT , and POD) activities. The MDA level was much higher in leaves than roots, whereas the activities of SOD, CAT, and POD were the opposite, suggesting their possible role in arsenic resistance and detoxification. Our results indicate the potential of V. natans in phytoremediation of arsenic-contaminated water.
研究领域:
环境科学
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植物修复
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水生生态学
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毒理学
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产品关联
DOI
PubMed
高影响因子
DALTON TRANSACTIONS
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2020
·Vol. 49
·期 18
·6119-6126
·
IF 4.174
Jinyuan Zhang,Huaimin Gu
Owing to their environmentally friendly characteristic, InP-based quantum dots (QDs) show great potential in various fields as an alternative to Cd-based QDs. However, the current mainstream synthesis process, the (TMS)3P-based injection method, still faces many challenges, such as the high cost of (TMS)3P and complex temperature control. In contrast, the solvothermal method is considered to be more feasible and reproducible. Despite its potential advantages, little has been done to understand how the precursors influence the synthesis of InP QDs using the solvothermal method. In this research, InZnP/ZnS QDs were synthesized using practical phosphorus precursors (DEA)3P or (DMA)3P. Through the feasible regulation of zinc, indium, phosphorus and sulfur precursors, the band gap of the QDs could be widely and accurately tuned, and a much wider photoluminescence wavelength ranging from 484 nm to 651 nm could be achieved. Furthermore, InI3 and InBr3 contributed to the blueshift in the PL wavelengths, and the combination of (DEA)3P, (DMA)3P, n-DDT and t-DDT refined the PL wavelength with a small tuning gap of 5 nm.
研究领域:
材料科学
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纳米技术
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化学
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产品关联
DOI
PubMed
高影响因子
Journal of Physical Chemistry Letters
·
2026
·
IF 4.5
Yao Fu,Jia Xu,Huifang Han,Zhenxu Sun,Xueqi Zhang,Kun Lang,Fan Shen,Yahan Wu,Xu Pan,Jie Yan,Jianxi Yao
The crystallization kinetics of all-inorganic perovskites critically influence the photovoltaic performance. Here, we introduce formamidinium acetate (FAAC) as a multifunctional additive to promote the conversion of DMAPbI3 and Cs4PbI6 intermediates into high-quality black-phase γ-CsPbI3 thin films. FAAC reduces the formation energy of the Cs4PbI6 intermediate, enabling its early formation during initial heating. Concurrently, FA+ cations rapidly intercalate into the DMAPbI3 lattice, forming a mixed (FA, DMA)Pb(I, AC)3 phase that facilitates complete cation exchange between DMA+ and Cs+ and accelerates DMAI removal. This synergistic effect effectively reduces residual DMA+ and structural defects. The optimized FAAC-based CsPbI3 perovskite solar cells (PSCs) achieve a power conversion efficiency (PCE) of 21.84%. Furthermore, the unencapsulated devices exhibit excellent operational stability, retaining 90% of their initial efficiency after 500 h under ambient conditions and 88.7% after 120 h of thermal aging at 85 °C.
✓ 已验证
DOI
PubMed
高影响因子
MOLECULAR PHARMACEUTICS
·
2022
·
IF 5.364
Ji Wang,Yanhao Zhang,Chao Liu,Wenhui Zha,Shuo Dong,Hanlei Xing,Xinsong Li
Protein kinase N3 (PKN3), by virtue of its abnormal expression in prostate cells, has been widely used as a target of RNAi (shRNA, siRNA, miRNA) therapy. The major challenges of PKN3 RNAi therapy lie in how to design effective interference sequences and delivery systems. Herein, new PKN3 shRNA sequences (shPKN3-2459 and shPKN3-3357) were designed, and bioreducible, biodegradable, ionizable lipid-based nanoparticles were developed for shPKN3 delivery. First, an ionizable lipid (DDA-SS-DMA) bridged with disulfide bond and ester bonds was synthesized by a three-step reaction and confirmed by MS, 1H NMR, and 13C NMR. The ionizable lipid was mixed with cholesterol, DSPC, PEG-lipid, and shPKN3 by a microfluidic mixer to prepare lipid nanoparticles (LNP–shPKN3) which were characterized by DLS and TEM. Afterward, the pH and glutathione (GSH)-responsiveness of the DDA-SS-DMA based LNP delivery system were investigated by lysosome escape and gel electrophoresis assays. Compared with the commercial transfection reagent Lipo2000, the DDA-SS-DMA based delivery system showed higher transfection efficiency and lower toxicity. Western blot analysis, invasion tests, and migration assays were performed to evaluate the silencing effect of shPKN3 in vitro. In in vivo studies, high tumor suppression (65.8%) and treatment safety were evident in the LNP–shPKN3-2459 treatment group. Taken together, the DDA-SS-DMA based delivery system encapsulating shPKN3-2459 showed significant antitumor efficacy and might be a promising formulation for the treatment of prostate cancer.
研究领域:
药学
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分子生物学
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癌症研究
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纳米技术
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药物递送系统
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DOI
PubMed
高影响因子
CHEMOSPHERE
·
2016
·
IF 3.698
Ying Han,Zhong-lin Chen,Ji-min Shen,Ji-he Wang,Wei-wei Li,Jun Li,Bin-yuan Wang,Li-na Tong
The role of Cu(II) in the reduction of N -nitrosodimethylamine (NDMA) with zero-valent metals was investigated by determining the effects of Cu(II) on the removal, kinetics, products, and mechanism. NDMA removal was enhanced, and all reactions followed a pseudo-first-order kinetic model except for the Fe and Fe/0.1 mM Cu(II) systems. The iron mass-normalized pseudo-first-order rate constants ( k MFe ) increased with the Cu(II) concentration. The zinc mass-normalized pseudo-first-order rate constants ( k MZn ) were identical to those with the Cu(II) concentrations from 0.1 mM to 1.0 mM and were higher with 2.0 mM Cu(II). The types of products detected were unchanged. Some unknown products were also found. NDMA was reduced to 1,1-dimethylhydrazine (unsymmetrical dimethylhydrazine , UDMH). Then, UDMH was reduced into dimethylamine (DMA) by the Fe/Cu(II) and Zn/Cu(II) systems. Catalytic hydrogenation was proposed as the reduction mechanism. Several copper species, such as Cu(OH) 2 in the Fe/Cu(II) system and Cu 2 O and Cu(OH) 2 in the Zn/Cu(II) system enhanced NDMA reduction. Differences between the Fe/Cu(II) and Zn/Cu(II) systems were caused by the reduction potentials and surface conditions of the different metals and the copper species in the various systems.
研究领域:
环境化学
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水处理
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催化
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化学工程
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产品关联
DOI
PubMed
高影响因子
DYES AND PIGMENTS
·
2017
·
IF 3.473
Liangwei Ma,Chengpeng Li,Qiufeng Liang,Sheng Wang,Derong Cao
We designed and synthesized three new tetraphenylethene (TPE) derivatives ( CZ-TPE , DMA-TPE and TPA-TPE ) modified with different electron rich group (carbazole, N, N -dimethylaniline and triphenylamine segments, respectively) by Knoevenagel condensation reaction. The chemical structures of these compounds are identified by NMR, MS and IR. The absorption and emission of these dyes were investigated by UV-Vis and fluorescence spectroscopy , respectively. The results shown three dyes exhibited evident aggregation-induced emission (AIE) or aggregation-induced emission enhancement (AIEE) properties with wavelength tunable emission. Their emission color can be tuned from green to orange in tetrahydrofuran/H 2 O solutions, from green to red in solid state or pure tetrahydrofuran solutions. In addition, the solution or film of TPA-TPE shown results in distinct fluorescence from “ON” to “Off” observation as well as color change from orange yellow to colorless by naked eyes when the addition of toxic Cl 2 gas, which can be used as an excellent dual chromo- and fluorogenic signal changes that is well suited for monitoring Cl 2 gas in solution, or solid film, conveniently. These results indicate TPA-TPE is a promising candidate chemosensor for the detection of Cl 2 gas.
研究领域:
化学
·
材料科学
·
分析化学
·
环境科学
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DOI
高影响因子
LANGMUIR
·
2019
·
IF 3.683
Sizhe Liu,Qian Zhang,Ying Han,Yulong Sun,Yifei Zhang,Hongyu Zhang
In clinics it is extremely important for implanted devices to achieve the property of enhanced lubrication and bacterial resistance; however, such a strategy has rarely been reported in previous literature. In the present study, a surface functionalization method, motivated by articular cartilage-inspired superlubrication and mussel-inspired adhesion, was proposed to modify titanium alloy (Ti6Al4V) using the copolymer (DMA–MPC) synthesized via free radical copolymerization. The copolymer-coated Ti6Al4V (Ti6Al4V@DMA–MPC) was evaluated by X-ray photoelectron spectroscopy, water contact angle, and Raman spectra to confirm that the DMA–MPC copolymer was successfully coated onto the Ti6Al4V substrate. In addition, the tribological test, with the polystyrene microsphere and Ti6Al4V or Ti6Al4V@DMA–MPC as the tribopair, indicated that the friction coefficient was greatly reduced for Ti6Al4V@DMA–MPC. Furthermore, the bacterial resistance test showed that bacterial attachment was significantly inhibited for Ti6Al4V@DMA–MPC for the three types of bacteria tested. The enhanced lubrication and bacterial resistance of Ti6Al4V@DMA–MPC was due to the tenacious hydration shell formed surrounding the zwitterionic charges in the phosphorylcholine group of the DMA–MPC copolymer. In summary, a bioinspired surface functionalization strategy is developed in this study, which can act as a universal and promising method to achieve enhanced lubrication and bacterial resistance for biomedical implants.
研究领域:
材料科学
·
生物医学工程
·
表面化学
·
摩擦学
·
生物材料
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产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2021
·
IF 4.539
Lirong Yang,Chuanqun Huang,Xuan Luo,Lin Zhang,Yongjie Ye,Hui Jun,Yan Wang
Due to the high swelling ratio, the use of chitosan-based composites for adsorption of U(VI) from wastewater is limited. To overcome this shortcoming, a novel type of hierarchical porous chitosan-based aerogel (CS-PTA-DMAs) with anti-swelling is successfully prepared via cross-linking chitosan with the cross-linker PTA-DMA, which is synthesized by p-phthalaldehyde (PTA) and 3,5-diaminobenzoic acid (DMA). There is no significant volume expansion of the aerogel after soaking in ultrapure water for 1 week, indicating it has good swelling property. In addition, the CS-PTA-DMA aerogel has a high U(VI) adsorption capacity of 160 mg/g (308 K, pH 6). The adsorption behavior of CS-PTA-DMA to U(VI) is coordinate to the pseudo-second-order kinetic model and Freundlich isothermal model, which is spontaneously endothermic. Moreover, the adsorption mechanism is also investigated in details. These findings are crucial for the development of practical application uranium adsorbents.
研究领域:
环境科学
·
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
Inorganic and Nano-Metal Chemistry
·
2017
·
IF 0
Huimin Li,Shasha Li,Yuanrui Wang,Yafeng Li,Qian Qiao
In this article, two novel metal-organic frameworks (MOFs) have been constructed by tuning the metal ions using identical ligand—FDA. Although both of them contain linear trinuclear secondary building unit (SBU) and infinite chain along with SBU, the different metal ions as node can result in the different connection of FDA. As a result, compound I shows 4,4-networks, and compound II contains 3-ring and 4-ring.
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DOI
JOURNAL OF DENTISTRY
·
2021
·
IF 4.379
Kang Li,Zhongni Zhang,Yuhong Sun,Hongye Yang,James Kit Hon Tsoi,Cui Huang,Cynthia Kar Yung Yiu
Objectives To evaluate the anti-proteolytic and cross-linking effect of N -(3,4-dihydroxyphenethyl)methacrylamide (DMA) on the demineralized dentin matrix in vitro . Methods Four experimental solutions were selected: 50% ethanol/water solution (Control); 1, 5, and 10 mmol/L DMA dissolved in 50% ethanol/water solution. Sound human molars were sectioned to produce dentin beams with dimension of 1×1×6 mm. The dentin beams were demineralized with 10% phosphoric acid for 8 h to remove the apatite . The demineralized specimens were randomly separated into four groups and immersed in the four experimental solutions for 1 h. After the treatment , the ultimate tensile strength (UTS), loss of dry mass and the release of hydroxyproline by storing the treated specimens in 0.1 mg/mL collagenase solution for 24 h were assessed. The swelling ratio of another ten specimens from each group were evaluated. The interaction between DMA with dentin matrix was observed under Field Emission Scanning Electron Microscopy (FESEM). UTS data was analyzed by two-way ANOVA followed by Tukey test, and the other data was analyzed by one-way ANOVA followed by Tukey test (α = 0.05). Results The two-way ANOVA factors, different solutions ( p < 0.001), collagenase degradation ( p < 0.001) and their interactions ( p < 0.001) all significantly affected the UTS. The 10 mM DMA treatment significantly decreased the percentage of loss of dry mass, release of hydroxyproline and swelling ratio of demineralized dentin matrix compared to other treatment groups ( p < 0.05). The FESEM observation depicted that with increasing concentration of DMA, the structure of dentin matrix was protected and the porosity within dentin collagen network was decreased. Conclusions The treatment by 10 mM DMA/ethanol solution for 1 hour is capable of enhancing the mechanical properties of demineralized dentin matrix against collagenase degradation and may be clinically useful to improve the durability of hybrid layer. Clinical Significance The 10 mM DMA/ethanol primer may offer an alternative choice for dentists to strengthen the mechanical properties of demineralized dentin matrix and resist its degradation by collagenase.
研究领域:
牙科学
·
材料科学
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生物材料
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DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）