INORGANIC CHEMISTRY
·
2023
·
IF 4.6
Dongsheng Zhao,Wenqian Li,Rongmei Wen,Nana Lei,Wencui Li,Xin Liu,Xiutang Zhang,Liming Fan
With the introduction of Eu3+ ions as the secondary fluorescent signal reporter and sensing active sites, a dual-emission ratiometric sensor of Eu3+@NiMOF (Eu3+ functional NiMOF) for hippuric acid (HA) detection in urine and serum was fabricated via the postsynthetic encapsulating strategy. Based on the two emission signals at 441 nm (turn-on) and 628 nm (turn-off), the produced Eu3+@NiMOF ratiometric sensor provided enhanced sensitivity, higher selectivity, and 9.7 times lower limits of detection (LOD) for the detection of HA (2.38 μM, 0.42 μg·mL–1) than that of the pristine NiMOF. Considering the high sensitivity and visualization results, further exploration of intelligent applications in the HA sensing process was carried out by constructing a tandem combinational logic gate to improve the practicability and convenience with the help of a smartphone. This work provides a promising approach for developing MOF-based ratiometric sensors to detect biomarkers.
研究领域:
生物传感
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材料科学
·
分析化学
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产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2020
·
IF 3.99
Zhongqian Hu,Qingyou Deng,Shuaishuai Yang,Dongcai Guo
A series of novel 2-quinolone ligands and their corresponding Eu(III) complexes were prepared. The effect of different solvents, different ligand concentrations and different substituents on the fluorescence intensity of ligands were investigated in detail. The fluorescence intensity of Eu(III) complexes were studied by comparing different substituents on the ligand. The results indicate that all ligands show the strongest fluorescence intensity in ethanol with the ligand concentration of 50 μM. Among these ligands, the ligand (K 6 ) containing -COOCH 3 group owns the strongest fluorescence intensity and the corresponding fluorescence quantum yield reaches 0.317. All complexes exhibit characteristic red light of Eu(III) ions with good thermal stability. The effect of diverse substituents on the fluorescence intensity is ordered: -COOCH 3 >-Cl> -Br> -OCH 3 >-CH 3 >-H, which indicates the complex [EuK 6 (NO 3 ) 3 ]·2H 2 O with the strongest electron-donating group (-COOCH 3 ) possesses the strongest fluorescence intensity. The above analysis shows that the ligand (K 6 ) and corresponding Eu(III) complex [EuK 6 (NO 3 ) 3 ]·2H 2 O own the best fluorescence property, which has an outstanding application prospect in the field of optical materials and biomedicine materials.
研究领域:
无机化学
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材料科学
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物理化学
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生物化学
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产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2024
·
IF 4.3
Xuequan Jing,Meina Guo,Jiarong Li,Wei Xu,Haonan Qin,Weidong Xiao,Yinhua Wan,Jieliang Chen,Zhangwei Yao,Weijie Song,Hongdong Yu,Kang Hu,Tinggang Li
The overuse of quinolone antibiotics has led to a series of health and environmental issues. Herein, we combine the distinct luminescence properties of Eu 3+ with the unique structure of covalent organic frameworks (COFs) to develop a precise and sensitive fluorescent probe for detecting Flumequine (Flu) in water. Eu 3+ is thoroughly anchored into the channels of COFs as recognition sites, while the synthesized probe material still maintains its intact framework structure. The unique structure of COFs provides excellent support and protection for Eu 3+ . Therefore, COF-Eu can rapidly bind with Flu which can transfer the absorbed energy to Eu 3+ through an “antenna effect”, resulting in red fluorescence. Moreover, there is a good linear relationship between Flu concentration in the range of 0–30 µM, with a detection limit of 41 nM. Simultaneously, the material maintains remarkable reproducibility, with its performance remaining almost unchanged after five cycles of use. Remarkably, the probe demonstrates excellent Flu recovery rates in real samples. This study provides a viable approach for the recognition of flumequine in the environment through a customized fluorescence detection method.
研究领域:
分析化学
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环境科学
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材料科学
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产品关联
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2018
·Vol. 185
·期 10
·1-8
·
IF 5.705
Pang Jiawei,Lu Yuexiang,Gao Xinyu,Song Panshu,Yang Fengyi,Liu Yueying
A selective phosphorescent on-off-on probe with long decay lifetime has been designed for the detection of pyrophosphate ions (PPi). The detection scheme is based on the use of europium(III)-modulated Mn(II)-doped ZnS quantum dots capped with N-acetyl-L-cysteine. Both the aggregation of quantum dots and electron transfer induced by Eu(III) ions cause phosphorescence to be quenched (“off” state). Phosphorescence is, however, restored on addition of PPi to the system (“on” state). The effect is attributed to the removal of Eu(III) from the carboxy groups on the surface of the quantum dots owing to the stronger interaction between PPi and Eu(III). A linear relationship exists between phosphorescence intensity (best measured at excitation/emission wavelengths of 316/594 nm) and PPi concentration in the 400 nM to 6000 nM with a detection limit of 145 nM. An additional attractive feature is provided by the long-lived phosphorescence (1920 μs) of the quantum dots. It can be used to eliminate interference by short-lived fluorescence in biological samples by performing time resolved measurements. The probe was applied to the determination of PPi in spiked in urine samples and gave recoveries in the range from 98 to 105% with RSDs of <2.0%.
Schematic of a long-lived phosphorescent on-off-on probe for the sensitive and selective detection of pyrophosphate ions (PPi). It is based on the use of Eu(III)-modulated Mn(II)-doped ZnS quantum dots (QDs). Phosphorescence is quenched of QDs after the addition of Eu 3+ but restored after the addition of PPi.
研究领域:
分析化学
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材料科学
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生物化学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF SOLID STATE CHEMISTRY
·
2021
·
IF 3.498
Juncheng Zhou,Yuhao Chen,Shuang Xian,Yicun Liang,Guojia Huang,Lian Wang,Xiaozhan Yang
A novel europium metal-organic frameworks (Eu-MOFs), based on 1,3,5-benzotricarboxylic acid (H 3 BTC), 4,4′-azopyridine (4,4′-AZ) and N , N -dimethyllformamide (DMF), was synthesized by the solvothermal method . The crystal structure, thermal stability, morphology and luminescent properties are characterized by the X-ray diffraction (XRD), thermogravimetry (TG), scanning electron microscope (SEM), X-ray photoelectron spectroscopy (XPS) and optical spectroscopic techniques. The Eu-MOFs display a unique luminescence quenching effect to nitrobenzene (NB) and copper (Cu 2+ ) ions. The turn-off luminescence can be induced by 210 ppm NB or by 1000 μM Cu 2+ ions. Furthermore, the high sensitivities ( K SV = 0.039 ppm −1 for NB, and K SV =0.029 μM −1 for Cu 2+ ) and low detection limits (0.656 ppm for NB, and 1.395 μM for Cu 2+ ) are obtained. The sensing mechanisms are reasonably explained based on the electron and energy transfer. The experimental results show that the Eu-MOFs can be used as a potential sensing luminescence quenching probes for NB and Cu 2+ ions.
研究领域:
材料科学
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分析化学
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环境科学
·
光学
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产品关联
DOI
高影响因子
APPLIED CLAY SCIENCE
·
2021
·
IF 5.467
Junming Zhou,Hongmei Liu,Dong Liu,Peng Yuan,Hongling Bu,Peixin Du,Wenxiao Fan,Mengyuan Li
Weathered crust elution-deposited rare earth (WED-RE) ores are important rare earth element (REE) resources around the world. In these ores, the REE are believed to mainly exist as exchangeable REE(III) ions on the surfaces of clay minerals, such as tubular halloysite and platy kaolinite . However, the mechanisms underlying the sorption and desorption of REE(III) ions on clay minerals in the environment of weathered crusts remain ambiguous. In this study, the sorption/desorption characteristics of Eu(III) ions onto halloysite and kaolinite were investigated. The results revealed that Eu(III) was adsorbed onto both clay minerals through inner-sphere complexation and outer-sphere complexation, where the former was the primary sorption mechanism. Halloysite displayed a higher sorption capacity for Eu(III) than kaolinite in a weakly acidic environment (pH 4–6). The desorption efficiency increased with the increasing concentration of NH 4 + ions. When the NH 4 + concentration was 0.002 mol/L, which is similar to the typical cation concentration of groundwater/rainwater, the amount and rate of Eu(III) desorption from halloysite were lower than those from kaolinite. The desorption of Eu(III) ions from the two clay minerals is proposed to be governed by the attraction between the outer-sphere complexes and clay minerals when the NH 4 + concentration is 0.002 mol/L. Therefore, halloysite has a higher sorption capacity and stronger retention capacity for Eu(III) than kaolinite, which suggests that halloysite may play a greater role in REE(III) enrichment in WED-RE ores than kaolinite owing to the similar chemical properties of REE(III) ions. The fundamental results obtained in this study afford new insights into the migration of REE and the role of clay minerals in REE enrichment during ore formation.
研究领域:
地质学
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环境科学
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产品关联
DOI
高影响因子
INORGANIC CHEMISTRY
·
2015
·
IF 4.762
Jingyan Sun,Bo Song,Zhiqiang Ye,Jingli Yuan
Singlet oxygen (1O2) plays a key role in the photodynamic therapy (PDT) technique of neoplastic diseases. In this work, by using a 9,10-dimethyl-2-anthryl-containing β-diketone, 1,1,1,2,2-pentafluoro-5-(9′,10′-dimethyl-2′-anthryl)-3,5-pentanedione (Hpfdap), as a 1O2-recognition ligand, a novel β-diketonate–europium(III) complex that can act as a luminescence probe for 1O2, [Eu(pfdap)3(tpy)] (tpy = 2,2′,2″-terpyridine), has been designed and synthesized for the time-gated luminescence detection of 1O2 in living cells. The complex is weakly luminescent due to the quenching effect of 9,10-dimethyl-2-anthryl groups. After reaction with 1O2, accompanied by the formation of endoperoxides of 9,10-dimethyl-2-anthryl groups, the luminescence quenching disappears, so that the long-lived luminescence of the europium(III) complex is switched on. The complex showed highly selective luminescence response to 1O2 with a remarkable luminescence enhancement. Combined with the time-gated luminescence imaging technique, the complex was successfully used as a luminescent probe for the monitoring of the time-dependent generation of 1O2 in 5-aminolevulinic acid (a PDT drug) loaded HepG2 cells during the photodynamic process. In addition, by coloading the complex and a mitochondrial indicator, Mito-Tracker Green, into HepG2 cells, the specific localization of [Eu(pfdap)3(tpy)] molecules in mitochondria of HepG2 cells was demonstrated by confocal fluorescence imaging measurements.
研究领域:
生物化学
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医学影像
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药物化学
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产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2024
·
IF 8
Yu Kang,Ludi Wang,Yaoyang Liu,Runquan Shi,Xiaoyan Tang,Li Wang
Efficient and selective sensing of lanthanides are crucial for identifying valuable lanthanide streams and designing effective extraction/masking agents for mining and nuclear waste management. Luminescence-based sensing often struggles with interference from water molecules. Common approaches to improve emissive lanthanide complexes in water involve increasing ligand lipophilicity and enclosing the emitting metal center. Herein, we have demonstrated that lipophilic ligands do not always lead to higher emissions. When strong coordinating groups are involved in the ligand, the complex may adapt special architecture to compensate the hydrophilic nature of the ligand by creating lipophilic microenvironment and lead to higher emissions. Our findings highlight the importance of the overall lipophilicity of both the ligand and the final complex, which could serve as important reference for future design of efficient lanthanide sensing and emissive complexes.
研究领域:
化学
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材料科学
·
环境科学
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DOI
高影响因子
POLYMER INTERNATIONAL
·
2024
·
IF 2.9
Fang Wu,Xinfei Zhang,Qi Wang,Dayang Yu,Pan Zheng,Rongli Zhu,Xu Wang,Zejun Pu,Jiachun Zhong
In order to expand the application of biobased polycarbonate in optical components, a series of isosorbide polycarbonate (PICC)/rare earth ion complex fluorescent composites were prepared by using PICC as a macromolecular ligand and Eu 3+ and Tb 3+ as rare earth luminescence centers. The coordination system between rare earth ions and PICC was investigated by Fourier transform infrared spectroscopy, DSC and TGA. On adjusting the ratio of Eu 3+ and Tb 3+ , a PICC/rare earth ion composite with adjustable fluorescence color was obtained. Also, the thermal, mechanical and optical properties of a series of PICC/rare earth ion fluorescent films with different ratios were tested. A transparent fluorescent composite material with excellent mechanical properties and tunable fluorescent colors has been prepared. © 2024 Society of Industrial Chemistry.
研究领域:
材料科学
·
光学工程
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产品关联
DOI
高影响因子
MOLECULES
·
2024
·Vol. 29
·期 17
·4259
·
IF 4.2
Jing Li,Yu Liang,Chun Tian,Hongyan Zou,Lei Zhan,Lijuan Wang,Chengzhi Huang,Chunmei Li
Bacillus anthracisis a Gram-positive bacterium that can cause acute infection and anthracnose, which is a serious concern for human health. DeterminingBacillus anthracisthrough its spore biomarker dipicolinic acid (DPA) is crucial, and there is a strong need for a method that is rapid, sensitive, and selective. Here, we created Eu(III)-coordination polymers (Eu-CPs) with surfaces that have abundant carboxyl and hydroxyl groups. This was achieved by using citric acid and europium nitrate hexahydrate as precursors in a straightforward one-pot hydrothermal process. These Eu-CPs were then successfully utilized for highly sensitive DPA determination. The fluorescence (FL) emission of Eu-CPs, which is typically weak due to the coordination of Eu(III) with water molecules, was significantly enhanced in the presence of DPA. This enhancement is attributed to the competitive binding between DPA’s carboxyl or hydroxyl groups and water molecules. As a result, the absorbed energy of DPA, when excited by 280 nm ultraviolet light, is transferred to Eu-CPs through an antenna effect. This leads to the emission of the characteristic red fluorescence of Eu3+at 618 nm. A strong linear relationship was observed between the enhanced FL intensity and DPA concentration in the range of 0.5–80 μM. This relationship allowed for a limit of detection (LOD) of 15.23 nM. Furthermore, the Eu-CPs we constructed can effectively monitor the release of DPA from Bacillus subtilis spores, thereby further demonstrating the potential significance of this strategy in the monitoring and management of anthrax risk. This highlights the novelty of this approach in practical applications, provides a valuable determination technique for Bacillus anthracis, and offers insights into the development cycle of microorganisms.
研究领域:
微生物学
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分析化学
·
生物医学
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产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Zhen-Wen Zhang,Ao-Jun Qiu,Geng-Jin-Sheng Cheng,Yu Fan,Yu Xiao,Yan-Zhu Liu,Qian-Yong Cao
Tetracycline detection remains an important research topic in the bioenvironmental field today. This paper reports a novel amphiphilic Eu(III) complex DO 3 AC 12 -Eu for single signal and ratiometric fluorescence detection of tetracycline (TC) in aqueous solution. DO 3 AC 12 -Eu can self-assemble micelle-like nano-aggregation in aqueous solution with no fluorescence. After addition of TC, the Eu(III)-based emission was observed for the effective antenna effect from TC to Eu(III) center. In addition, DO 3 AC 12 -Eu can load 4-methylumbelliferone sodium (MU) as a fluorescence reference to form DO 3 AC 12 -Eu/MU co-assembly nano-aggregation with a blue emission at 450 nm. Based on the TC-induced antenna effect and inner filter effect mechanism between TC and MU, DO 3 AC 12 -Eu/MU exhibits a ratiometrically fluorescent response toward TC, with increasing Eu(III)-based emission at 615 nm, and decreasing MU-based emission at 450 nm. Importantly, DO 3 AC 12 -Eu/MU exhibits superior sensitivity and selectivity over DO 3 AC 12 -Eu . The detection limit of DO 3 AC 12 -Eu/MU toward TC is 0.82 nM, far lower than that of DO 3 AC 12 -Eu (9.5 nM). Furthermore, DO 3 AC 12 -Eu/MU assembly has been successfully used for on-site and real-time detection of TC in food samples by using the smartphone-based visualization method and test gel.
研究领域:
分析化学
·
环境监测
·
生物环境科学
·
荧光传感技术
·
纳米科技
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配位化学
·
食品安全检测
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF PORPHYRINS AND PHTHALOCYANINES
·
2019
·Vol. 23
·期 06
·619-627
·
IF 1.292
Pan Chen,Ya-Fan Huang,Guang-Yu Xu,Jin-Ping Xue,Juan-Juan Chen
To improve the cancer targeting and anticancer efficacy, the multifunctional Eu-based metal-organic framework (EuBTC) is post-synthetically modified with a targeting moiety folic acid and a zinc phthalocyanine photosensitizer. In addition, this nanosphere is also applied as a drug delivery system to load the chemical drug doxorubicin. Electron microscopy, powder X-ray diffraction and infrared spectometry demonstrated the formation of these multifunctional nanospheres (DOX). Our nanospheres kept the high singlet oxygen quantum yield of zinc phthalocyanine. Additionally, Cell viability experiments demonstrated the biosafety of EuBTC and the enhanced anticancer effect of DOX@FA-EuBTC-Pc under light irradiation. In short, these well-arranged DOX@FA-Eu-BTC-Pcs exhibit as promising drug delivery systems for enhanced targeted anticancer therapy.
研究领域:
材料科学
·
纳米医学
·
癌症治疗
·
药物递送
·
光动力治疗
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）