FOOD CHEMISTRY
·
2023
·
IF 8.8
Yan Wu,Yue Zhou,Hongchen Long,Xiangyu Chen,Yuanyuan Jiang,Lei Zhang,Tao Le
The study investigates a bimetallic organic framework (Zn/Eu-MOF) based fluorescent probe for visual detection of ofloxacin (OFL) in pork, beef and fish. The developed sensing probe recognizes OFL through internal filtration and cation-π interaction between OFL and Zn/Eu-MOF, resulting in a distinct color change from orange-red to light green. The content of OFL can be determined through RGB analysis by a mobile-phone. The developed sensing probe offers several advantages such as broad linear range (0.1 ∼ 80 μM), rapid response time (30 s), low detection line (0.44 μM). The effectiveness of the sensing probe can last for five rounds with good recovery. Moreover, the application of the sensing probe on pork, beef and fish samples are reliable, with recoveries ranging from 93.4 to 112.1%, and the relative standard deviations (RSD) within 1.17% to 2.06%. These results suggest that the developed sensing probe could have significant potential for practical on-site test in food.
研究领域:
食品科学
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分析化学
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生物传感
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DOI
PubMed
高影响因子
Analytical Methods
·
2024
·
IF 2.7
Huifeng Xu,Weihua Huang,Rui Pan,Ronglin Chen,Lili Wang,Yun Yu,Xihai Li,Xi Zhu
A stable dual-emission fluorescent system, R6G/Eu-MOF, was obtained by simple mixing Eu-MOF with fluorescent rhodamine 6G (R6G). This system not only achieved robust dual luminescence performance at 430 nm (Eu-MOF) and 555 nm (R6G) under single-wavelength excitation, but also endowed it significantly improved fluorescence stability. Orientin (OT), a bioactive traditional Chinese medicine (TCM) component, was found to efficiently quench the dual fluorescent emissions via the synergistic effect of dynamic quenching effect, photo-induced electron transfer and molecular interactions. Therefore, a rapid fluorescent assay for OT was developed based on the variations in fluorescence signals at 430 nm and 555 nm, as well as the alterations in the ratio between these two signals. This method can achieve highly sensitive determination of OT in the linear range of 1.1-220 µM, with a LOD of 0.26 µM at 430 nm and 0.16 µM at 555 nm (3σ/N). The R6G/Eu-MOF hybrid exhibits significantly lower detection limits and a broader linear range OT than either R6G or Eu-MOF alone. This work presents a simple strategy to improve the water stability of Eu-MOF, and also provides a rapid analysis of small molecule drug using a fluorescence approach based on dual-emission MOF hybrid system.
研究领域:
分析化学
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药物分析
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材料科学
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DOI
PubMed
高影响因子
Journal of Materials Chemistry C
·
2023
·Vol. 11
·期 8
·2995-3002
·
IF 6.4
Wenwei Lai,Chuanli Wu,Xiuxun Han
CsPbBr3 nanocrystals (NCs) exhibit great potential for various optoelectronic applications due to their excellent optoelectrical properties. However, the poor stability inherited from the ionic crystal structure limits their practical applications. Hence, coupling CsPbBr3 NCs with protective and functional materials for achieving superior properties is one of the current research challenges. Herein, three-dimensional hyperbranched structures of Eu-MOF were developed as effective frameworks coupled with CsPbBr3 NCs. Rich Eu-MOF morphologies including sheaf-like, dumbbell-like, and urchin-like ones were achieved in a controllable way via introducing an Al(Ac)3 additive. The crystal splitting growth mechanism was found to dominate the formation of hierarchical Eu-MOF structures, as evidenced by the time-dependent morphological evolution of an urchin-like Eu-MOF. In addition, acidic carboxylate salts (such as Al(Ac)3, Zn(Ac)2, Pb(Ac)2, Cu(Ac)2, Ni(Ac)2) effectively modulate the splitting of Eu-MOF crystal growth, which is deemed to be the synergistic effect of metal ions and acetate ions. Subsequently, a series of CsPbBr3/Eu-MOF composites were synthesized by pre-preparing various Eu-MOF hyperbranched structures, and they demonstrate excellent dual-emissive optical properties. A ratiometric fluorescence probe fabricated by encapsulating CsPbBr3 in the three-dimensional hyperbranched Eu-MOF structure exhibits remarkable sensitivity, good linearity, and high selectivity for DMF detection.
研究领域:
材料科学
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化学
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纳米技术
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光电
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分析化学
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DOI
高影响因子
JOURNAL OF FLUORESCENCE
·
2025
·
IF 3.1
Yao Jie,Chen Hongfang,Yang Xiaohua,Iqbal Muzaffar,Bian Wei
Mercury ions (Hg 2+ ) are categorized as environmental pollutants, which distributed in water, soil, and food systems due to environmental contamination. Hence, designing a sensitive assay for the convenient determination of Hg 2+ is of great importance. Herein, S and O-doped graphite phase nitrogenized carbon quantum dots (S, O-C 3 N 4 QDs) was encapsulated within a europium -based metal-organic framework (Eu-MOF) to construct a novel ratiometric fluorescent nanoprobe for the quantitative detection of Hg 2+ . The native emission of S, O-C 3 N 4 QDs at 445 nm is used as a response signal, while Eu-MOF with fluorescence offers a reference signal at 619 nm. Hg 2+ exhibits high affinity for the surface functional groups of S/O-C 3 N 4 QDs, forming non-fluorescent chelation complexes that induce static quenching. This results in significant attenuation of the fluorescence intensity at 445 nm, while the emission at 619 nm remains invariant. A ratiometric fluorescence sensing platform was established based on the intensity ratio (F 445 /F 619 ) for the selective detection of Hg 2+ . The linear range of S, O-C 3 N 4 QDs/Eu-MOF of Hg 2+ was 0.25–35 µM and with a detection limit of 4.3 nM. The satisfying results demonstrate the effectiveness of the developed S, O-C 3 N 4 QDs/Eu-MOF-based fluorescence probe for Hg 2+ detection, highlighting its promising potential for environmental monitoring applications.
研究领域:
环境科学
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分析化学
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材料科学
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纳米技术
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产品关联
DOI
PubMed
高影响因子
Analytical Methods
·
2023
·
IF 3.1
Xin-Xin Dong,Tao-Li Chen,Xiangjuan Kong,Shuang Wu,Fang-Fang Kong,Qiang Xiao
In this work, a facile fluorescence Eu3+-based metal organic frameworks (Eu MOF) sensor for ascorbic acid (AA) and ascorbate oxidase (AAO) detection was developed. The fluorescence of Eu MOF could be effectively quenched by Ce3+ but not Ce4+ at an appropriate concentration, thus, when the reductant AA was added into the solution containing Ce4+, Ce4+ was chemically reduced to Ce3+, which induced the decreased fluorescence signal of Eu MOF. However, when AAO was introduced, AA was effectively oxidized to dehydroascorbic acid (DHAA) under the catalysis of AAO, thus, Ce4+ could not be reduced, resulting in the fluorescence restore of Eu MOF. Hence, the concentration of AA and AAO could be determined by the fluorescence decrease and restore of Eu MOF. The fluorescent platform showed high sensitivity with the limit of detection of 0.32 µM for AA and 1.18 U/L for AAO, respectively. Moreover, the proposed method was successfully applied for AA and AAO determination in real samples, indicating great potential for biomedical application in complex matrices.
研究领域:
分析化学
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生物医学工程
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材料科学
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DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 4
·1-11
·
IF 5.3
Ma Minghao,Hu Wei,Luo Shengdong,Pei Fubin,Lei Wu,Wang Jiang,Tong Zhaoyang,Liu Bing,Du Bin,Hao Qingli,Mu Xihui
Horseradish peroxidase (HRP) was used as a model glycoprotein, and a molecularly imprinted ratiometric fluorescence sensor based on a smartphone (NEB@MIP) was constructed using the sol–gel method for the fluorescence and visual detection of HRP. The sensor consisted of boronic acid-functionalized metal–organic frameworks (Eu-MOF-B(OH) 2 ) and nitrogen-doped carbon dots (N-CDs). The Eu-MOF-B(OH) 2 surface can not only load abundant N-CDs but also covalently bind with HRP through its boronic acid groups. The NEB@MIP exhibited two fluorescence emission peaks at 450 nm and 616 nm. When HRP was present, the fluorescence was quenched due to the internal filtering effect (IFE), but the quenching of N-CDs was more pronounced. Furthermore, the concentration of HRP in the range 0.05–10 µM showed a good linear relationship with the ratio of fluorescence intensity at 616 nm and 450 nm, with a detection limit (LOD) of 0.01 µM. Meanwhile, the sensor displayed a noticeable change in fluorescence color under different concentrations of HRP targets. Moreover, the sensor achieved satisfactory results in detecting simulated real samples, with recoveries ranging from 92.0% to 98.5% and RSDs between 1.5% and 3.3%. The detection platform based on the smartphone also performed well when detecting HRP in simulated real samples. Thus, this work provided a new approach for the portable detection of HRP. The method provides a new idea for the combination of ratiometric fluorescence molecular imprinting of glycoproteins and the portable detection platform of smart phones. Graphical
研究领域:
分析化学
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生物传感
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材料科学
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DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2021
·
IF 7.46
Yang Li,Jia-Jia Li,Qing Zhang,Jian-Yong Zhang,Na Zhang,Yong-Zheng Fang,Jinwu Yan,Qinfei Ke
The highly emissive BODIPY (boron-dipyrromethene) have been grafted on the Eu-based metal-organic frameworks (Eu-MOFs) via the covalent F-B bonding using a facile one-pot solvothermal reaction. The fluorescence emission ratio of [email protected] has been applied to construct the ratiometric fluorescence sensor for the F - , H 2 O 2 and glucose detection in water solution and living cells. The produced [email protected] probe provided enhanced sensitivity, higher selectivity and lower lower limits of detection (LOD) for the detection of F - (0.1737 μM), H 2 O 2 (6.22 nM) and glucose (6.92 nM), and 5.96, 6.52 and 6.95 times lower than that for single Eu-MOF, respectively. More importantly, the probe also exhibited the lower biotoxic in living cells for bioimaging and the better visualization performance with multiplex channels. The results indicated the π-conjugated BODIPY derivative not only acted as the surfactant molecule or template agent for preferred growth, but also modulated the fluorescent emissions drastically, and thus induced excellent fluorescent detecting performances.
研究领域:
纳米技术
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分析化学
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生物医学工程
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生物化学
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产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2024
·
IF 4.3
Wenqing Li,Jingyue Zhang,Linhan Fan,Yun Zhao,Changyan Sun,Wenjun Li,Zhidong Chang
Aniline is an organic pollutant with carcinogenicity and teratogenicity, while F - and Hg 2+ are toxic ions that are easily soluble in water. When they are released to the environment, they will pose a threat to human health. Designing a material that can simultaneously detect three types of pollutants is of great significance. In this paper, a novel rare earth metal organic framework material (Eu-MOF) with three-dimensional structure based on 1-methylimidazole-4,5-dicarboxylic acid was synthesized for the first time through solvent thermal method. It has excellent luminescent performance and can be used as a multifunctional fluorescent probe to detect aniline, F - , and Hg 2+ based on photoinduced electron transfer, energy competitive absorption, and ion exchange mechanisms, with detection limits of 1.79 × 10 -8 , 8.13 × 10 -8 , and 8.83 × 10 -7 M, respectively. It is worth noting that Eu-MOF can detect F - and Hg 2+ in real water samples, such as lake water and green tea water, with favorable recovery rates.
研究领域:
材料科学
·
环境化学
·
分析化学
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产品关联
DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2024
·
IF 7.4
Zhiguo Yu,Hao Guo,Zeyun Yang,Mingyue Wang,Wu Yang
Tannic acid (TA) is a natural polyphenol that is widely used as a preservative and antioxidant in foods, beverages, health products and pharmaceuticals. In this study, a novel Eu-MOF skeleton was prepared using a simple solvothermal strategy and used as a ratio-metric fluorescence sensor for the ultra-sensitive detection of TA. The constructed Eu-MOF has excellent fluorescence properties and high stability in the aqueous phase. With the introduction of TA, a special covalent structure is formed between the o-diphenol group of TA and the boric acid hydroxyl group in ligand of the MOF, resulting in a gradual decrease in the red emission of Eu-MOF at 614 nm and a basically invariable blue emission at 420 nm. As the concentration of TA increased, the color of the system also changes from red to blue, thus achieving rapid and sensitive detection with a low limit of detection (LOD) of 75.6 nM through a ratiometric fluorescence strategy. What is more, Eu-MOF fluorescent probe combined with smart phone color detector is used to visually detect TA. The propose method is successfully applied in the target analysis in tea and beverage samples and the recovery is 95.6∼110.0 %, which is proved to be an effective strategy for the food safety and healthy monitoring.
研究领域:
分析化学
·
食品安全
·
材料科学
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产品关联
DOI
高影响因子
LUMINESCENCE
·
2015
·Vol. 31
·期 1
·190-194
·
IF 1.518
Guangya Jin,Zhijian Liu,Hongfa Sun,Zhiyong Tian
A lanthanide metal coordination polymer [Eu 2 (BDC) 3 (DMSO)(H 2 O)] was synthesized by the reaction of europium oxide with benzene-1,3-dicarboxylic acid (H 2 BDC) in a mixed solution of dimethyl sulfoxide (DMSO) and water under hydrothermal conditions. The crystal structure of Eu 2 (BDC) 3 (DMSO)(H 2 O) was characterized by X-ray diffraction (XRD). Thermo-gravimetric analysis of Eu 2 (BDC) 3 (DMSO)(H 2 O) indicated that coordinated DMSO and H 2 O molecules could be removed to create Eu 2 (BDC) 3 (DMSO)(H 2 O)-py with permanent microporosity, which was also verified by powder XRD (PXRD) and elemental analysis. Both Eu 2 (BDC) 3 (DMSO)(H 2 O) and Eu 2 (BDC) 3 (DMSO)(H 2 O)-py showed mainly Eu-based luminescence and had characteristic emissions in the range 550–700 nm. Copyright © 2015 John Wiley & Sons, Ltd.
研究领域:
材料科学
·
化学
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产品关联
DOI
PubMed
高影响因子
CARBOHYDRATE POLYMERS
·
2020
·
IF 7.182
Haiping Wang,Yujia Pei,Xueren Qian,Xianhui An
Metal-organic frameworks (MOFs) are emerging highly crystallized three-dimensional network complex formed by self-assembling metal ions and organic ligands. However, all MOFs are nanoscale and micro scale powder materials, which greatly impedes their further applications. In this study, a transparent Eu-MOF@TEMPO-oxidized cellulose nanofibrils (Eu-MOF@TOCNF) photoluminescence material for specifically detecting copper ions was fabricated via in-situ synthesis in hydroalcoholic medium. Scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, Fluorescence spectrometer and other equipment were applied to characterize functionalized TOCNF film samples, and the results confirmed the successful fabrication of the functionalized TOCNF film with stable fluorescence properties. The film performed a high selectivity toward copper ion in the presence of other interfering metal ions. The fluorescence intensity of the film decreased gradually with the increase of copper ion concentration, and I 0 / I -1 developed a good linear relationship with [Cu 2+ ], which made the film a promising material for detecting Cu 2+ in water body.
研究领域:
材料科学
·
环境科学
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DOI
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2025
·
IF 6.2
Wang Guo,Yiqing Guo,Hong Xu,Chen Li,Xinai Zhang,Xiaobo Zou,Zongbao Sun
Staphylococcus aureus (S. aureus) is a major pathogenic bacterium responsible for bacterial foodborne diseases, making its rapid, specific, and accurate detection crucial. In this study, we develop a ratiometric biosensor based on the recombinase polymerase amplification-clustered regularly interspaced short palindromic repeats/CRISPR associated protein 12a (RPA-CRISPR/Cas12a) system and Eu-metal–organic framework (Eu-MOF) fluorescent nanomaterials for the high-sensitivity detection of S. aureus, combining with RPA for efficient isothermal amplification, this sensor enhances specificity and sensitivity by utilizing the target activation of CRISPR/Cas12a. The Eu-MOF serves a dual function, providing stable red fluorescence as a reference signal and adsorbing FAM-labeled probes for fluorescence quenching, forming a dual-signal system that significantly reduces background interference. This ratiometric design enables accurate and quantitative detection over a wide range (7.9 × 100 to 7.9 × 108 CFU/mL) with a low detection limit of 3 CFU/mL. Overall, with these merits of simplicity, rapid response, high sensitivity, and specificity, this dual-signal biosensor offers a promising method for accurately evaluating S. aureus contamination in food under complex substrate conditions.
研究领域:
生物技术
·
食品安全检测
·
分子诊断
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）