Animal Nutrition
·
2025
·
IF 7.5
Xinyao Zhang,Ke Cheng,Lixue Dong,Dexing Zhu,Qingyong Li,Zhongbao Guo,Yongju Luo,Apeng Liu,Juan Tian,Di Peng,Jianmin Zhang,Yangyang Liu,Hua Wen,Ming Jiang
Fava bean is currently utilized as a specialized feed ingredient to enhance the muscle texture of fish. When incorporated at appropriate levels, fava beans can improve fish muscle crispy texture. However, high dietary levels of fava beans may lead to liver damage in fish, although the specific mechanisms behind this effect remain unclear. In this study, 600 genetic improvement of farmed tilapia (GIFT; Oreochromis niloticus ) of uniform size (initial body weight 552.3 ± 10.12 g) and healthy appearance were randomly divided into four groups, each with three replicates of 50 fishes. The fish diets contained different levels of fava beans (0, 50%, 60%, and 70%), designated as D0, D50, D60, and D70, respectively, over a ten-week feeding experiment. A comprehensive analysis of the impact of fava beans on muscle texture and liver health in GIFT was performed. The results showed that 50%, 60%, and 70% dietary fava beans had no significant effect on the growth performance of GIFT ( P > 0.05), but 70% dietary fava beans increased feed conversion ratio (FCR) ( P = 0.022). Consumption of fava beans at levels of 50%, 60%, and 70% in the diet altered GIFT muscle texture ( P < 0.05), and adversely effected serum biochemistry and liver health ( P < 0.05). Non-targeted metabolome analysis of the liver revealed that dietary fava beans may cause irreversible damage to liver cells by disrupting the DNA methylation process ( P < 0.05). This finding enhances the understanding of the mechanisms behind the negative impact of fava bean consumption on liver function. It is crucial to investigate potential strategies to mitigate these adverse effects while maintaining the desired muscle quality when fava beans are used in aquatic feed.
研究领域:
水产养殖学
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分子生物学
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营养学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Plants-Basel
·
2022
·Vol. 11
·期 4
·515
·
IF 4.658
Ihsein Rokia Amine-Khodja,Alexandre Boscari,Nassira Riah,Maya Kechid,Rim Tinhinen Maougal,Nadir Belbekri,Abdelhamid Djekoun
Drought stress has become one of the most uncontrolled and unpredictable constraints on crop production. The purpose of this study was to evaluate the impacts of two differentRhizobium leguminosarumstrains on terminal drought tolerance induction in two faba bean genotypes cultivated in Algeria, Aquadulce and Maltais. To this end, we measured physiological parameters—osmoprotectants accumulation, oxidative stress markers and enzyme activities—to assess the effect ofR. leguminosaruminoculation onV. fabaunder terminal water deficiency conditions in greenhouse trials. Upregulation of anti-oxidative mechanisms and production of compatible solutes were found differentially activated according toRhizobiumstrain. Drought stress resilience of the Maltais variety was improved using the localRhizobiumstrain OL13 compared to the common strain 3841. Symbiosis with OL13 strain leads in particular to a much better production of proline and soluble sugar in nodules but also in roots and leaves of Maltais plant. Even if additional work is still necessary to decipher the mechanism by which aRhizobiumstrain can affect the accumulation of osmoprotectants or cellular redox status in all the plants, inoculation with selectedRhizobiumcould be a promising strategy for improving water stress management in the forthcoming era of climate change.
✓ 已验证
DOI
高影响因子
Journal of Biobased Materials and Bioenergy
·
2017
·Vol. 11
·期 5
·505-509
·
IF 0.975
Pan Shaobing,Qiu Fengxian,Ping Zhang,Geng Rong,Xu Xueqin,Huang Tongxing,Ma Yichen,Yang Jiahui,Li Houzhi
Objectives: This paper focuses on comparing the micronucleus effect and evaluating genotoxicity of nano-zinc oxide and bulk-zinc oxide based on V. faba. root tip cells. Methods: The different concentration of nano-ZnO and bulk-ZnO suspensions are used as mutagens,
meanwhile, the paper calculates the micronucleus permillage of V. faba. root tip cells exposed by different treatment liquid. Results: 1. Both nano-ZnO and bulk-ZnO suspensions can induce higher micronucleus permillage. The micronucleus permillage induced by different concentration
of nano-ZnO and bulk-ZnO are all higher than the negative control group. The significance comparison of micronucleus permillage between bulk-ZnO and negative control group is significant (p < 0.05) and the significance comparison between nano-ZnO and negative control group is extremely
significant (p < 0.01), both of difference comparison have statistical significance. 2. The micronucleus permillage which is induced by nano-ZnO is higher than bulk-ZnO on the equal concentration. The significance comparison of them is extremely significant (p < 0.01),
the comparison has statistical significance. The genotoxicity to V. faba. root tip cells of nano-ZnO is higher than bulk-ZnO. 3. It has stronger operability and scientificalness that we use the optimized micronucleus test technique of V. faba. root tip cells to evaluate genotoxicity
of manufactured nanomaterials.
研究领域:
遗传学
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毒理学
·
环境科学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）