The novel Fe-doped MoS2/granulated activated carbon (GAC) particle electrodes (FMG PEs) were controllably synthesized by a hydrothermal method and used in the three-dimensional (3D) electroactivation of peroxydisulfate (E-PDS-FMG) for carbamazepine (CBZ) degradation. The performance, mechanism, and influencing factors of CBZ degradation by the E-PDS-FMG system were systematically discussed. Electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV) analyses showed that the E-PDS-FMG system has an excellent conductivity and a high electron transfer rate and exhibited a superior electrocatalytic performance for CBZ degradation. A CBZ removal rate greater than 99% can be achieved within 25 min under the conditions of FMG dosage of 0.4 g L−1, PDS concentration of 2.0 mM, current density of 1.0 mA cm−2, and initial pH value of 5. Sulfate radicals (SO4·−) and hydroxyl radicals (OH) were recognized as the major active species through quenching experiments and electron paramagnetic resonance (EPR) measurement. In addition, Fe (IV) was also involved in the E-PDS-FMG system according to the transformation of methyl phenyl sulfoxide (PMSO) to methyl phenyl sulfone (PMSO2). Furthermore, the possible mechanism of the E-PDS-FMG system was proposed. FMG PEs were applied as the catalyst and particle electrodes for PDS activation, improving the yield of OH, SO4·−, and Fe (IV). The increase of FMG dosage and PDS concentration accelerated the degradation of CBZ, and the E-PDS-FMG system exhibited a high degradation ability on CBZ removal in a wide pH range. The results all indicate that the E-PDS-FMG system is a promising technology for organic pollutant removal from water due to its excellent electrocatalytic performance and remarkable stability.
Impaired wound healing imposes great health risks to patients. Recently, mesenchymal stem cell (MSC) therapy has shown potential to improve the healing process, but approaches to employ MSCs in the treatment of wounds remain elusive. In this study, we reported a novel electrohydrodynamic (EHD) cyroprinting method to fabricate micropatterned fiber scaffolds with polycaprolactone (PCL) dissolved in glacial acetic acid (GAC). Cyroprinting ensured the formation of a porous structure of PCL fibers by preventing the evaporation of GAC, thus increasing the surface roughness parameter Ra from 11 to 130 nm. Similar to how rough rocks facilitate easy climbing, the rough surface of fibers was able to increase the adhesion of adipose-derived MSCs (AMSCs) by providing more binding sites; therefore, the cell paracrine action of secreting growth factors and chemokines was enhanced, promoting fibroblast migration and vascular endothelial cell tube formation. In rat models with one-centimeter wound defects, enhanced MSC therapy based on porous PCL fiber scaffolds improved wound healing by augmenting scarless collagen deposition and angiogenesis and reducing proinflammatory reactions. Altogether, this study offers a new and feasible strategy to modulate the surface topography of polymeric scaffolds to strengthen MSC therapy for wound healing. Graphic Abstract
Bayberry pomace, a nutrient-rich material abundant in dietary fiber (DF), has historically been underutilized due to a lack of thorough research. This study aimed to investigate the physicochemical and functional properties of the DF. Ultrasonic enzymatic treatment was performed to extract the total DF, which was then optimized to produce modified soluble dietary fiber (MSDF) and insoluble dietary fiber (MIDF). The optimized conditions yielded 15.14% of MSDF with a water-holding capacity (WHC) of 54.13 g/g. The DFs were evaluated for their structural, physicochemical, and functional properties. The MSDF showed a higher (p< 0.05) WHC, oil-holding capacity (OHC), swelling capacity (SC), cation exchange capacity (CEC), and glucose adsorption capacity (GAC) (about 14.15, 0.88, 1.23, 1.22, and 0.34 times) compared to the DF. Additionally, the MSDF showed strong, superior radical scavenging and blood sugar-lowering capabilities, with a more porous surface morphology. A Fourier-transform infrared (FT-IR) spectroscopy analysis indicated that enzymatic modification degraded the cellulose and hemicellulose, reducing the DF crystallinity. Overall, the results demonstrated that cellulase hydrolysis could effectively improve the physicochemical and functional properties of DF, thereby paving the way for its development into functional food products.
危险品化学品经营许可证（带存储）