CHEMICAL PHYSICS LETTERS
·
2019
·
IF 1.901
Hongwei Feng,Hui Xu,Hongtu Feng,Ying Gao,Xinyuan Jin
The sol-gel method was used to synthesize Gd-SiO 2 -TiO 2 composite photocatalysts. When the doping amounts of Si and Gd reached 9.1 mol% and 0.2 mol% respectively, the sample showed the optimal photocatalytic activity during the methylene blue (MB) degradation. When the calcination temperature was lower than 550 °C, Gd-SiO 2 -TiO 2 photocatalyst has an anatase crystal structure. After doping of Si and Gd, the absorption wavelength thresholds of the sample approached 407 nm with the energy gap of 3.05 eV. Gd-SiO 2 -TiO 2 photocatalyst showed the degradation efficiency about 90% to methylene blue (MB) under irradiation of simulated sunlight.
研究领域:
材料科学
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环境科学
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产品关联
DOI
高影响因子
Frontiers in Bioengineering and Biotechnology
·
2022
·
IF 6.064
Song Xianji,Liu Xilin,Ma Yihang,Zhu Qingsan,Bi Mingchao
It is important for future clinical applications to design and synthesize multipurpose scaffolding materials for bone tissue engineering with high osteogenic induction and MRI capability. In the present study, we synthesized Ce/Gd@HA by co-doping Ce3+ and Gd3+ into hydroxyapatite (HA) using a hydrothermal synthesis method, and then Ce/Gd@HA composites were synthesized by combining Ce/Gd@HA nanoparticles with polylactic-co-glycolic acid (PLGA) to investigate whether implanted Ce/Gd@HA/PLGA composites could promote osteoblast viability, leading to tibia repair of the rats and enhance MRI. The measurement results contain X-ray diffraction (XRD), Fourier-transform infrared (FTIR) spectroscopy, and environmental scanning electron microscopy (ESEM) showing that HA doped with Ce3+ and Gd3+ was still a hexagonal crystal with high crystallinity. The synthesized Ce/Gd@HA/PLGA composites have a structure and obvious magnetic resonance imaging (MRI) capability. The in vitro experimental results indicated that Ce/Gd@HA/PLGA composites significantly promoted the performance of MC3T3-E1 cells, containing proliferation, adhesion, and osteogenic differentiation capacities. These include the improvement of alkaline phosphatase activity, enhancement of mineral deposition, and upregulation of OCN and COL-1 gene expression. The in vivo experimental results demonstrated that the Ce/Gd@HA/PLGA composites significantly improved the healing rate of rat bone defects. The MRI images indicated that the Ga-doped composites were observed in the MRI T1 sequence in rats. The aforementioned results suggested that Ce/Gd@HA/PLGA composites not only effectively promoted bone formation but also enhanced MRI capability. The composites synthesized in this study have great potential in bone regeneration with an extensive application in bone tissue engineering.
研究领域:
生物材料学
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组织工程学
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医学影像学
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DOI
PubMed
高影响因子
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2018
·Vol. 102
·期 5
·2415-2425
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IF 2.956
Jingyuan Chu,Yue Zhao,Guangyu Jiang,Wei Wu,Zhiwei Zhang,Zhiyong Hong,Zhijian Jin
Tuning substrate properties is an effective methodology to modulate the texture development of MgO films deposited by ion beam-assisted deposition (IBAD) process for epitaxial oxide films. Herein, a solution deposition planarization (SDP) technique is employed to deposit Gd-Zr-O layer for engineering surface properties of the flexible metal substrate. The correlation between the Gd-Zr-O thin film microstructure and the IBAD-MgO texture is investigated. The coordinated study on atomic force microscopy (AFM) and reflection high-energy electron diffraction (RHEED) reveal that the grain coarsening during high-temperature sintering negatively influences the texture formation of IBAD-MgO. Moreover, the chemical environment of the atoms on the surface of Gd-Zr-O seed layer also plays a critical role, which is normally overlooked. The X-ray photoelectron spectroscopy (XPS) analysis indicates that the carbon residue and intermediate phase result in the poor texture of the IBAD-MgO. This phenomenon is related to the partial decomposition and synthesis reactions due to the lower sintering temperature or reduced surface to volume ratio. We demonstrate the high-quality texture of IBAD-MgO layer, deposited on mono-coated thick Gd-Zr-O film, by using optimal heat-treatment conditions. The cross-sectional TEM images present the dense Gd-Zr-O film with Gd 2 Zr 2 O 7 nanograins. The multifunctionalities, such as planarization, a barrier layer, and seed layer, of Gd-Zr-O layers are realized in full-stacked CeO 2 /LaMnO 3 /IBAD-MgO/SDP-Gd-Zr-O/C276 samples. This work demonstrates a route for simplifying the architecture of 2G-HTS using Gd-Zr-O layer and explores the effect of the surface properties on texture formation in IBAD-MgO layer.
研究领域:
材料科学
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物理学
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产品关联
DOI
高影响因子
JOURNAL OF RARE EARTHS
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2020
·
IF 3.104
Xiangcheng Shi,Jingjie Yang,Xintong Wen,Fuli Tian,Changyan Li
Cerium oxide-based nanozymes have recently drawn much attention in the field of biomedical and antioxidant applications, because of their unique regenerative or autocatalytic properties. Herein, we studied the biomimetic superoxide dismutase (SOD) nanozymes CeO 2 -Gd that combines the fluorescence properties of rare earth Gd with the antioxidant properties of CeO 2 nanoparticles , which was prepared via facile route. The structure and composition of the CeO 2 -Gd were measured and verified by X-ray powder diffraction (XRD), Raman spectroscopy , transmission electron microscopy (TEM), energy-dispersive X-ray spectroscopy (EDX), and X-ray electron spectroscopy (XPS). Confocal microscopy was used to image cells. Antioxidant performance and cell viability of these nanozymes were measured in vitro using BGC-803 cell. CeO 2 -Gd nanozymes with a higher Ce 3+ /Ce 4+ ratio show higher superoxide dismutase (SOD) mimetic activity. Their antioxidant activity and fluorescence properties of CeO 2 -Gd in BGC-803 cancer cells are enhanced by oxygen vacancies generated by doping rare-earth elements Gd. This work may guide the future design of CeO 2 -Gd-based biomimetic nanozymes for anticancer and antioxidant applications.
研究领域:
纳米技术
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生物医学工程
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材料科学
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生物化学
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细胞生物学
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产品关联
DOI
高影响因子
JOURNAL OF NANOBIOTECHNOLOGY
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2024
·Vol. 22
·期 1
·1-14
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IF 10.6
Chen Tongtong,Cai Zhengwei,Zhao Xinxin,Wei Gang,Wang Hanqi,Bo Tingting,Zhou Yan,Cui Wenguo,Lu Yong
By integrating magnetic resonance-visible components with scaffold materials, hydrogel microspheres (HMs) become visible under magnetic resonance imaging(MRI), allowing for non-invasive, continuous, and dynamic monitoring of the distribution, degradation, and relationship of the HMs with local tissues. However, when these visualization components are physically blended into the HMs, it reduces their relaxation rate and specificity under MRI, weakening the efficacy of real-time dynamic monitoring. To achieve MRI-guided in vivo monitoring of HMs with tissue repair functionality, we utilized airflow control and photo-crosslinking methods to prepare alginate-gelatin-based dual-network hydrogel microspheres (G-AlgMA HMs) using gadolinium ions (Gd (III)), a paramagnetic MRI contrast agent, as the crosslinker. When the network of G-AlgMA HMs degrades, the cleavage of covalent bonds causes the release of Gd (III), continuously altering the arrangement and movement characteristics of surrounding water molecules. This change in local transverse and longitudinal relaxation times results in variations in MRI signal values, thus enabling MRI-guided in vivo monitoring of the HMs. Additionally, in vivo data show that the degradation and release of polypeptide (K 2 (SL) 6 K 2 (KK)) from G-AlgMA HMs promote local vascular regeneration and soft tissue repair. Overall, G-AlgMA HMs enable non-invasive, dynamic in vivo monitoring of biomaterial degradation and tissue regeneration through MRI, which is significant for understanding material degradation mechanisms, evaluating biocompatibility, and optimizing material design.
研究领域:
生物医学工程
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材料科学
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医学影像学
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DOI
高影响因子
RSC Advances
·
2022
·Vol. 12
·期 5
·3097-3107
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IF 4.036
Enli Liu,Junyou Shi,Xue Lin,Wenbiao Xu,Liyun Feng,Yuanzhi Hong
The selective recovery of Gd(III) from wastewater is very meaningful for the prospective development of economics and the environment. To overcome disadvantages of poor adsorption capacity, low selectivity and complex preparation process in conventional adsorbents, herein a new ionic imprinted carboxymethyl chitosan (CMC) sponge functionalized by hyperbranched polyethyleneimine (PEI) with a 3D network structure (PEI-CMC-IIS) was successfully prepared and applied in the selective adsorption of Gd(III). The PEI-CMC-IIS is endowed with lots of amino groups due to the combination of biomass CMC with highly branched PEI, which is helpful for the adsorption of Gd(III). The imprinting sites are located at the surface of channels in PEI-CMC-IIS, which can achieve the adsorption specificity to Gd(III) and improve adsorption capacity. It is found that the maximum adsorption capacity of PEI-CMC-IIS is 38.64 mg g−1 at pH = 7. Meanwhile, the selectivity tests suggest that the PEI-CMC-IIS presents preferential adsorption for Gd(III) with a distribution coefficient of 437.5 mL g−1. Furthermore, the PEI-CMC-IIS displays excellent reusing and regeneration ability. Our findings will bring about potential application in fabrication of other high-efficiency adsorbents for selective adsorption of Gd(III).
研究领域:
环境科学
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材料科学
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产品关联
DOI
PubMed
高影响因子
FUSION ENGINEERING AND DESIGN
·
2021
·
IF 1.453
Wenxian Wang,Jie Zhang,Shipeng Wan,Tingting Zhang
The constitutive equation of the 155/157 Gd areal density and thermal neutron shielding rate was established by Monte Carlo N Particle Transport Code (MCNP) and used to design the novel Gd/316L stainless steel thermal neutron shielding materials. When the 155/157 Gd areal density is greater than 0.01 g/cm 2 , the thermal neutron absorption rate of the Gd/316L composite reaches approximately 99%. The novel thermal neutron shielding materials with different Gd (1 wt.%, - 5 wt.%,) contents were prepared at 950 °C by spark plasma sintering. The transition layer composed of FeNi 3 , GdNi, and Gd 3 Ni can be formed during the sintering process. Meanwhile, the mechanical properties of Gd/316L composites decrease with the increase of the Gd content. In H 3 BO 3 solution, pitting corrosion and galvanic corrosion occur at the interface between Gd and 316L matrix.
研究领域:
材料科学
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核工程
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物理学
✓ 已验证
产品关联
DOI
高影响因子
Nanoscale
·
2021
·Vol. 13
·期 24
·10943-10952
·
IF 7.79
Hui Zhang,Tianze Wu,Yi Chen,Qianqian Zhang,Zhenxia Chen,Yun Ling,Yu Jia,Yongtai Yang,Xiaofeng Liu,Yaming Zhou
Integrating magnetic resonance (MR) and photoacoustic (PA) contrast agents into porous nanomaterials is a favorable way for screening of potential theranostic nanomedicines. Hollow carbon nanospheres (HCSs) dotted with GdPO4 and γ-Fe2O3 (Gd–Fe) nanoparticles are therefore prepared and studied in this work. The resultant Gd–Fe/HCSs possess a size of ∼100 nm with a cavity of ∼80 nm and a shell thickness of ∼10 nm, where the magnetic Gd–Fe nanoparticles are dotted. Owing to the synergistic effects, the Gd–Fe/HCSs give 2.5 times enhanced PA signals as compared with HCSs as well as the inherited MR imaging properties from Gd–Fe nanoparticles. In vivo MR and PA imaging of the liver in mice are consequently evaluated and validated. Furthermore, taking the tunable particle size, hollow cavity, shell thickness, and dotted amounts of nanoparticles into consideration, our studies here provide a useful structural model for the synergistic integration of MR and PA imaging in HCSs.
研究领域:
医学影像学
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纳米医学
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产品关联
DOI
PubMed
高影响因子
ANALYST
·
2023
·Vol. 149
·期 4
·1169-1178
·
IF 4.2
Chen Xu,Jie Sun,Chenhao Zhang,Lu Yang,Hong Kan,Daguang Zhang,Guan Xue,Kai Dong
With the rapid development of nanotechnology and biomedicine, numerous gadolinium (Gd)-based nanoparticle MRI contrast agents have been widely investigated. Due to the unique physicochemical properties of nanoparticles and the complexity of biological systems, the biosafety of Gd-based nanoparticle MRI contrast agents has been paid more and more attention. Herein, for the first time, we employed an ultra-high performance liquid chromatography–electrospray ionization quadrupole time-of-flight/mass spectrometry (UPLC-ESI-QTOF/MS)-based metabolomics approach to investigate the potential toxicity of Gd-based nanoparticle MRI contrast agents. In this work, NaGdF4 and PEG-NaGdF4 nanoparticles were successfully constructed and selected as the representative Gd-based nanoparticle MRI contrast agents for the metabolomics analysis. Based on the results of metabolomics, more metabolic biomarkers and pathways were identified in the NaGdF4 group than those in the PEG-NaGdF4 group. Careful analysis of these metabolic biomarkers and pathways suggested that NaGdF4 nanoparticles induced disturbance of pyrimidine and purine metabolism, inflammatory response, and kidney injury to a certain extent compared with PEG-NaGdF4 nanoparticles. These results indicated that Gd-based nanoparticle contrast agents modified with PEG had better biosafety. Additionally, it was demonstrated that the discovery of characteristic metabolomics biomarkers induced by nanoparticles would provide a new approach for biosafety assessment and stimulate the development of nanomedicine.
研究领域:
医学
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药理学
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纳米生物学
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毒理学
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产品关联
DOI
PubMed
高影响因子
INORGANIC CHEMISTRY
·
2024
·
IF 4.3
Xiaotong Yu,Zhijun Wang,Pei Cai,Kai Guo,Junyan Lin,Shuankui Li,Juanjuan Xing,Jiye Zhang,Xinxin Yang,Jing-Tai Zhao
Zintl compounds have continuously received significant attention, primarily due to their structural characteristics that align with the properties of the electron crystal and phonon glass. In this study, the crystal structure and thermoelectric properties of the quaternary Zintl chalcogenide BaScCuTe3 are investigated. The band structure calculations for BaScCuTe3 reveal a slight energy split of 0.08 eV between the second valence band and the valence band maximum, suggesting the presence of multiband-transport behaviors. Substitution of rare earth Gd for Sc is conducted, which significantly increases the hole concentration from 4.1 × 1019 cm–3 to 8.2 × 1019 cm–3 at room temperature. Meanwhile, the Seebeck coefficient increases because of the participation of the second valence band. A maximum power factor of 6.56 μW/cm·K2 at 773 K is obtained, which is 72% higher than that of the pristine sample. Moreover, the lattice thermal conductivity decreases from 0.57 W/m·K for BaScCuTe3 to 0.48 W/m·K for BaSc0.97Gd0.03CuTe3 at 773 K, owing to the introduction of point-defect scattering. As a result, there is a noteworthy improvement in the thermoelectric figure of merit zT, increasing from 0.44 for the undoped sample to 0.85 for BaSc0.98Gd0.02CuTe3. Considering these findings, BaScCuTe3 exhibits great potential and holds promise for further investigation in the field of thermoelectric materials.
研究领域:
材料科学
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物理学
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DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2012
·Vol. 36
·期 6
·1335-1338
·
IF 2.605
Sa Huang,Jianhua Liu,Di Liu,Qinghai Yuan
We report the facile and scalable synthesis of a highly monodispersed inorganic nanostructure based on well-designed Gd(OH)3 nanorods. X-Ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), as well as energy-dispersive spectroscopy (EDS) were applied to characterize the samples, indicating that the nanomaterials with an average length of 100 nm and an average diameter of 15 nm showed a typical hexagonal phase. Biocompatibility tests were performed from in vitro cell experiments to in vivo long-term histological assessment, indicating that the Gd(OH)3 nanorods were promising for further bio-related application. Owing to the excellent paramagnetic behavior, we further investigated the capability of the nanorods as MRI contrast agent. Compared with the conventional Gd–DTPA complex, the well-designed Gd(OH)3 nanorods present a higher T1 relaxation rate, showing more potential for biomedicine applications.
研究领域:
材料科学
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医学影像
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2025
·
IF 5.6
Changle Mei,Jixiang Yue,Fenxing Ye,Changming Wang,Yanglin Luo,Qingrong Yao,Jianqiu Deng,Lichun Cheng
Ion doping can significantly enhance microwave absorption performance. In this paper, powders of Sr 1- x Gd x MnO 3 ( x = 0, 0.02, 0.04, 0.06) were synthesized via a simple sol-gel process. Comprehensive characterization elucidated the phase evolution, microstructure, valence states, magnetic properties, and electromagnetic attenuation mechanisms of Gd-doped SrMnO 3 . With the incorporation of Gd 3+ , the crystal structure of Sr 1- x Gd x MnO 3 transitions from hexagonal to cubic. The crystal lattice develops substantial defects, while the resulting valence imbalance drives the reduction of Mn 4+ to Mn 3+ . These synergistic effects enhance multipolarization phenomena, including defect polarization and charge polarization. Notably, the addition of an appropriate amount of Gd ions to the material can effectively adjust its electromagnetic parameters and optimizes impedance matching. Among the synthesized samples, Sr 0.94 Gd 0.06 MnO 3 exhibits optimal microwave absorption performance, achieving a minimum reflection loss of −36.6 dB at 9.84 GHz and an effective absorption bandwidth of 3.04 GHz at a thickness of 2.2 mm. Additionally, an effective absorption bandwidth of 4.0 GHz is achieved for x = 0.02 at a thickness of 1.6 mm. These results not only indicate that Gd 3+ doping significantly enhances the absorbing properties of SrMnO 3 but also provide valuable theoretical guidance for the design of high-efficiency electromagnetic wave absorption materials in future research.
研究领域:
材料科学
·
电磁学
·
固体物理
·
无机化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）