SENSORS AND ACTUATORS B-CHEMICAL
·
2018
·
IF 5.667
Haicong Shen,Kaixin Xie,Liping Huang,Lei Wang,Jianhua Ye,Meng Xiao,Lei Ma,Aiqing Jia,Yong Tang
Pseudorabies virus (PRV) is a pathogen that causes an acute infectious disease in pigs, which could lead to huge losses to the farming industry. The Bartha-K61 strain of PRV, commonly used as a gE-deleted vaccine, does not always protect against the wild-type virus infection effectively. Therefore, the prompt detection of viral infection in gE-deleted vaccine vaccinated pigs is crucial for in-time measures to prevent the spread of diseases. In this study, we developed a Surface-enhanced Raman spectroscopy(SERS) based lateral flow assay based on antigen-antibody reaction to meet the demand. Our method was rapid (15 min), sensitive (LOD: 5 ng mL −1 ), selective for wild-type PRV detection, and quantitatively or semi-quantitatively (DLR: 41–650 ng mL −1 ) compatible. The detection results from this method were consistent with results from the gE-specific PCR, indicating that this SERS-based lateral flow assay could be used as a new tool to differentially diagnose wild-type PRV and gE-deleted vaccine.
研究领域:
兽医学
·
分子生物学
·
诊断学
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Chemistry A
·
2020
·Vol. 8
·期 42
·22292-22301
·
IF 11.301
Junjie Fu,Dongxing Kou,Wenhui Zhou,Zhengji Zhou,Shengjie Yuan,Yafang Qi,Sixin Wu
A major obstacle hindering further development of kesterite Cu2ZnSn(S,Se)4 (CZTSSe) solar cells is the inherent recombination losses that occur both via bulk defects and charge extraction interfaces. Herein, we propose a generic Ag, Ge dual-gradient absorber architecture, involving a downshift of absorber VBM at the front contact and an upshift of absorber CBM at the back contact, to improve device performance. We experimentally show that the substitution of Cu by Ag allows for larger band bending at the p–n junction, and the substitution of Sn by Ge imposes an additional drift field within the quasi-neutral region. Additionally, the Ag and Ge ions diffusing into the bulk absorber passivate the deleterious CuZn and CuSn deep-level defects. In turn, accelerated charge extraction, transport and minimized recombination loss offered surprising gains in Voc and Jsc, and the dual-gradient device achieved a maximum efficiency of 12.26% with an improved Voc,deficit of 553 mV. This Ag, Ge graded-substitution approach offers an alternative absorber architecture to improve the Voc,deficit in future high-efficiency kesterite PV cells.
研究领域:
材料科学
·
光伏技术
·
半导体物理
✓ 已验证
DOI
高影响因子
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
·
2024
·Vol. 130
·期 3
·1-11
·
IF 2.5
Hu Jiaming,Han Xiuxun,Zhu Wuzhi,Wu Fangfang,Tan Xiaohui
Incorporating substitutional elements from groups I, II and IV is an important approach to improve the quality of kesterite thin films. Among the elements, Ag and Ge are most effective in promoting the performance of Cu 2 ZnSn(S,Se) 4 solar cells. Although several theoretical and experimental studies have been conducted on the Ag/Ge-alloyed kesterite, there are significant differences in the reported morphological characteristics, photovoltaic performance and even the optimal Ag/Ge substitution ratio due to different preparation processes utilized, which leads to difficulties in comparing the Ag-incorporated and Ge-incorporated kesterite solar cells. Currently, there is little literature on the comparative study concerned. Herein, we fabricated Ag-alloyed and Ge-alloyed kesterite solar cells based on the same solution method and process conditions, and laterally compared the effects of Ag substitution and Ge substitution on the phase compositions, morphologies, optical bandgaps, minority carrier lifetime and device performance of kesterite Cu 2 ZnSn(S,Se) 4 thin films.
研究领域:
材料科学
·
光伏技术
·
薄膜技术
·
固体物理
·
半导体器件
✓ 已验证
DOI
高影响因子
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
·
2021
·Vol. 21
·期 4
·2254-2258
·
IF 0
Chen Xiao,Liu Tao,Feng Chuanqi
Germanium (Ge) nanoparticles/multiwalled carbon nanotubes (Ge/MWCNTs) composite is synthesized by solvothermal method combined with heat treatment under H2 atmosphere. The Ge particles are buried in MWCNTs network to form expected composite. The MWCNTs not only improve the
conductivity of the composite but also act as a flexible matrix to buffer the volume change of germanium nanoparticles during the process of insertion and de-insertion in lithium ion battery system. The Ge/MWCNTs composite behaves better cycle performance and higher rate capability than those
of pure germanium (Ge) nanoparticles. The Ge/MWCNTs maintained discharge capacity as 1040 mAh·g-1 after 60 cycles at the current density of 100 mA·g-1. It is a promising anode material for lithium ion battery application.
研究领域:
材料科学
·
电化学
·
纳米技术
·
能源存储
✓ 已验证
DOI
PubMed
JOURNAL OF ALLOYS AND COMPOUNDS
·
2022
·
IF 6.371
Lirong He,Peng Zhou,Liping Wang,Mingyu Zhang,Qizhong Huang,Zhean Su,Xiaodong Wang,Ping Xu,Weijie Song,Renhao Zou
Improving the performance of anode materials is of great importance for lithium-ion batteries (LIBs). Transition metal selenides compositing carbon and germanium (Ge) have attracted extensive attention. In this work, an anode material that integrates Ge and α-MnSe in carbon nanofibers (CNFs) was first synthesized by heat treatment after electrospinning. The coupling of Ge with α-MnSe and carbon can cause the growth process of α-MnSe to occur inside the CNFs, which can buffer the volume change, refine the grains and avoid particles protruding from the surface of CNFs. In addition, the interconnected conductive network of Ge/α-MnSe@CNFs can provide fast diffusion channels for Li ions and improve the electrical conductivity . Importantly, there is a synergistic effect of Ge, α-MnSe, and CNFs on the anode material for LIBs. As expected, Ge/α-MnSe@CNFs exhibited an excellent performance with a capacity of 1514.7 mAh g −1 after 200 cycles at 0.1 A g −1 and 1030 mAh g −1 after 1000 cycles even at 1 A g −1 . Therefore, this new preparation strategy of Ge/α-MnSe@CNFs offers novel ideas to develop high-performance and long-life LIBs.
研究领域:
材料科学
·
电化学
·
纳米技术
·
能源存储
✓ 已验证
DOI
高影响因子
JOURNAL OF NON-CRYSTALLINE SOLIDS
·
2017
·
IF 2.124
Quan Guo,Yantao Xu,Haitao Guo,Xusheng Xiao,Changgui Lin,Xiaoxia Cui,Pengfei Wang,Fei Gao,Min Lu,Bo Peng
A serial (100 − x)Ge 25 Sb 10 S 65 -xI (x = 0, 5, 10, 15, 20, 25 and 30 wt%) chalcohalide glasses and ones doped with 0.1 wt% Dy 3 + rare-earth ions were synthesized and their structural, thermal and optical properties were systematically studied. It indicates that addition of I 2 into Ge 25 Sb 10 S 65 glass significantly decreases the connectivity of glass network and average bond energy, and modifies the associated properties. The glass transition temperature and refractive index decrease monotonically, and the density increases almost linearly with the increasing of iodine content in glass. The thermal stability is improved, which has a maximum of ΔT max = 174 °C. While the optical bandgap has a peak value at x = 10 wt%. The absorption spectra and mid-infrared fluorescence spectra of Dy 3 + rare-earth ions doped glasses were investigated together with the Judd-Ofelt analysis. GeS 2 nano-crystals were found in the sample with x ≥ 15 wt%, which is supposed to induce enhancements of mid-infrared fluorescence at 2.95 and 4.32 μm.
研究领域:
材料科学
·
光学
·
固体物理学
·
化学
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2023
·
IF 8.6
Hongrui Xiang,Feiping Zhao,Tao Wu,Xiaowei Zhang,Fei Chai,Qingwei Wang,Eveliina Repo,Xiaobo Min,Zhang Lin
Understanding the structure–activity relationship between the adsorption performance and accessible adsorption sites plays a vital role in developing efficient adsorbents for Ge(IV) recovery. Herein, three chitosan-based adsorbents were designed by grafting chitosan with p -hydroxybenzoic acid (HBA-CS), 3,4-dihydroxybenzoic acid (DBA-CS), and 3,4,5-trihydroxybenzoic acid (TBA-CS), and the phenolic hydroxyl amounts induced steric effect on Ge(IV) recovery was investigated. The results show that phenolic acids were successfully grafted onto the chitosan surface by an amidation reaction. The adsorption behavior of DBA-CS and TBA-CS conforms to the pseudo-second-order kinetic and Langmuir isotherm models, indicating that it is a single layer adsorption and chemisorption is the main adsorption process . The Ge(IV) recovery performance is correlated with the arrangement of the active adsorption sites and follows the order of TBA-CS > DBA-CS > HBA-CS. The steric effect of TBA-CS is more ideal than that of DBA-CS due to more phenolic hydroxyl groups, which endows it better affinity toward Ge(IV). Additionally, TBA-CS exhibits superior selectivity in the presence of competitive cations and interfering anions, and the adsorption efficiency was not significantly decreased after four regeneration cycles by the acid elution. The chelation adsorption sites for Ge(IV) provided by the o -phenolic hydroxyl groups are the dominant contribution, and the hydrogen bond and ideal steric effect further enhance the adsorption performance of TBA-CS. The structure regulation designed by steric hindrance optimization strategy to achieve high affinity is an attractive approach, which could be extended in the recovery of precious metal ions.
研究领域:
环境科学
·
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
NUCLEAR MEDICINE AND BIOLOGY
·
2018
·
IF 2.203
Weiyan Zhou,Weiqi Bao,Donglang Jiang,Yanyan Kong,Fengchun Hua,Xiuhong Lu,Yihui Guan
Introduction The objective of this study was to synthesize an N -methyl- d -aspartate receptor (NMDAR) radiotracer [ 18 F]-GE-179 in one-pot and evaluate its in vivo binding for NMDAR activation after brain ischemia reperfusion injury. Methods [ 18 F]-GE-179 was auto-synthesized using a quick one-pot method from a stable disulfide precursor and purified using semi-preparative high-performance liquid chromatography (HPLC) with ethanol/aqueous NaH 2 PO 4 as the eluent. Dynamic micro-positron emission tomography (PET)/computed tomography (CT) study of [ 18 F]-GE-179 was successfully performed using a rat model of middle cerebral artery occlusion (MCAO, induced by transient occlusion into the left MCA). A simplified reference tissue model method was used to calculate the [ 18 F]-GE-179 non-displaceable binding potential (BPND) for intracranial NMDAR activation assessment. Immunofluorescence staining of NMDAR NR1 subunit in brain slices containing lesion was also performed. Results [ 18 F]-GE-179 was successfully prepared in a yield of 23–30% in a formulation that could be injected directly after dilution. Localized radioactivity accumulation was observed in the animal model of MCAO. Significantly higher ( p = 0.0003–0.0404) BPND relative to equivalent contralateral was found in the ipsilateral caudate putamen , Acb core/shell, cortex cingulate , amygdala , hypothalamus , and superior colliculus . Immunofluorescence staining showed elevated NMDAR expression in the affected hemisphere. Conclusions [ 18 F]-GE-179 was synthesized using a one-pot process with a markedly improved yield. Preliminary in vivo micro-PET study visualized excessive NMDAR stimulation successfully in a rodent model of MCAO, which was consistent with results of in vitro immunofluorescence staining. The study demonstrates that [ 18 F]-GE-179 is a promising PET probe for the detection of functional NMDAR alterations.
研究领域:
神经科学
·
放射学
·
药理学
·
医学影像
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nanoscale
·
2016
·Vol. 8
·期 19
·10160-10165
·
IF 7.76
Wangen Zhao,Daocheng Pan,Shengzhong (Frank) Liu
Cu2ZnSn(S,Se)4 (CZTSSe) semiconductors have been a focus of extensive research effort owing to low-toxicity, high abundance and low material cost. Yet, the CZTSSe thin film solar cell has a low open-circuit voltage value that presents challenges. Herein, using GeSe2 as a new Ge source material, we have achieved a wider band gap CZTSSe-based semiconductor absorber layer with its band-gap controlled by adjusting the ratio of SnS2 : GeSe2 used. In addition, the Cu2Zn(Sn,Ge)(S,Se)4 thin films were prepared with optimal Ge doping (30%) and solar cells were fabricated to attain a respectable power conversion efficiency of 4.8% under 1.5 AM with an active area of 0.19 cm2 without an anti-reflection layer.
研究领域:
材料科学
·
光伏技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Arabian Journal of Chemistry
·
2023
·
IF 6
Yuhang Zhang,Shaoshuai Gao,Tingyu Zhao,Danshuo Chen,Rongli Wang,Yingjian Yu
The advantages of Ge-air batteries compared with metal-air batteries are their high anode utilization and ideal safety. To further enhance the discharge performance of Ge-air batteries, we report for the first time the successful synthesis of metal–organic segments (MOSs) material on the surface of germanium wafers by solution growth methods and demonstrate their performance in a button-type Ge-air battery with an alkaline gel polymer electrolyte . The morphology of MOSs can be controlled by adjusting the solution concentration and reaction time, and the discharge time of the battery would be elevated to about 350 h with prolonged reaction time. Our experimental findings prove that applying this MOSs material at the anode can significantly improve the discharge duration of Ge-air batteries. This paper also provides a strategy for anode modification to ameliorate the performance of Ge-air batteries.
研究领域:
材料科学
·
电化学
·
能源存储与转换
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2019
·Vol. 411
·期 18
·4025-4030
·
IF 3.286
Li Hao-Wen,Hua Xin,Long Yi-Tao
Time-of-flight secondary ion mass spectrometry (ToF-SIMS) has shown promising applications in single-cell analysis owing to its high spatial resolution molecular imaging capability. One of the main drawbacks hindering progress in this field is the relatively low ionization efficiency for biological systems. The complex chemical micro-environment in single cells typically causes severe matrix effects, leading to significant signal suppression of biomolecules. In this work, we investigated the signal enhancement effect of graphene quantum dots (GE QDs) in ToF-SIMS analysis. A × 160 magnification of ToF-SIMS signal for amiodarone casted on glass slide was observed by adding amino-functionalized GE QDs (amino-GE QDs), which was significantly higher than adding previously reported signal enhancement materials and hydroxyl group-functionalized GE QDs (hydroxyl-GE QDs). A possible mechanism for GE QD-induced signal enhancement was proposed. Further, effects of amino-GE QDs and hydroxyl-GE QDs on amiodarone-treated breast cancer cells were compared. A significant signal improvement for lipids and amiodarone was achieved using both types of GE QDs, especially for amino-GE QDs. In addition, ToF-SIMS chemical mapping of single cells with better quality was obtained after signal enhancement. Our strategy for effective ToF-SIMS signal enhancement holds great potential for further investigation of drug metabolism pathways and the interactions between the cell and micro-environment.
研究领域:
分析化学
·
生物医学工程
·
材料科学
·
细胞生物学
·
药学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Abdul Basit,Tanveer Hussain,Xin Li,Jiwu Xin,Bin Zhang,Xiaoyuan Zhou,Guoyu Wang,Ji-Yan Dai
Being a major obstacle, Ag2Te has always been restricted in p-type AgSbTe2-based materials to improve their thermoelectric performance. This work reveals a stabilized AgSbTe2 through Sn/Ge alloying as synthesized by melting, annealing, and hot press. Interestingly, addition of Sn/Ge in AgSbTe2 extended the solubility limit up to ∼30% and hence suppressed Ag2Te in Ag(1–x)SnxSb(1–y)GeyTe2 compounds and led to enhanced electrical transport. Moreover, electrical and thermal transport properties of AgSbTe2 have been greatly affected by the phase transition of Ag2Te near 425 K. However, high-entropy Ag0.85Sn0.15Sb0.85Ge0.15Te2 compound results in a stabilized rock-salt structure and presents a high power factor of ∼10.8 μW cm–1 K–2 at 757 K. Besides, density functional theory reveals that available multivalence bands in Sn/Ge-doped AgSbTe2 lead to reduction in energy offsets. Meanwhile, a variety of defects appear in the Ag0.85Sn0.15Sb0.85Ge0.15Te2 sample due to entropy change, and thus lattice thermal conductivity decreases. Ultimately, a high figure of merit of ∼1.5 is attained at 757 K. This work demonstrates a roadmap for other group IV–VI materials so that the high-entropy approach may inhibit the impurity phases with extended solubility limit and result in high thermoelectric performance.
研究领域:
材料科学
·
物理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）