JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
·
2016
·Vol. 31
·期 7
·1391-1399
·
IF 3.379
Jing Zhang,Beibei Chen,Han Wang,Xi Huang,Man He,Bin Hu
Microfluidic devices provide a potential platform that can specialize in miniaturization, integration and automation. In this study, we prepared ethanediamine modified poly glycidyl methacrylate trimethylol propane triacrylate monolithic columns (poly (GMA-co-TRIM-NH2)) in a microfluidic chip channel and established a novel method by combining chip-based poly (GMA-co-TRIM-NH2) monolithic microextraction with inductively coupled plasma mass spectrometry (ICP-MS) for the determination of bismuth in cell samples. Various factors affecting chip-based monolithic microextraction of bismuth were investigated. Under the optimized conditions, the limit of detection was 0.21 ng mL−1 and the relative standard deviation for bismuth was 6.0% (c = 5 ng mL−1, n = 7). The method was successfully applied to the analysis of HepG2 cells incubated with bismuth. With consumption of ∼600 cells, the average amount of bismuth was determined to be at the sub picogram level in a single cell. The prepared chip-based poly (GMA-co-TRIM-NH2) monolithic column had a high-surface area and exhibited high extraction efficiency towards bismuth. The proposed chip-based monolithic microextraction method combined with ICP-MS provides a novel strategy for the analysis of trace metals in cells.
研究领域:
分析化学
·
生物技术
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
GEOSTANDARDS AND GEOANALYTICAL RESEARCH
·
2013
·Vol. 38
·期 3
·345-354
·
IF 2.77
Jie Li,Xi-Rong Liang,Li-Feng Zhong,Xuan-Ce Wang,Zhong-Yuan Ren,Sheng-Ling Sun,Zhao-Feng Zhang,Ji-Feng Xu
en This link goes to a English section fr This link goes to a French section A novel preconcentration method is presented for the determination of Mo isotope ratios by multi-collector inductively coupled plasma-mass spectrometry (MC-ICP-MS) in geological samples. The method is based on the separation of Mo by extraction chromatography using N-benzoyl-N-phenylhydroxylamine (BPHA) supported on a microporous acrylic ester polymeric resin (Amberlite CG-71). By optimising the procedure, Mo could be simply and effectively separated from virtually all matrix elements with a single pass through a small volume of BPHA resin (0.5 ml). This technique for separation and enrichment of Mo is characterised by high selectivity, column efficiency and recovery (~ 100%), and low total procedural blank (~ 0.18 ng). A 100 Mo- 97 Mo double spike was mixed with samples before digestion and column separation, which enabled natural mass-dependent isotopic fractionation to be determined with a measurement reproducibility of < 0.09‰ (δ 98/95 Mo, 2 s ) by MC-ICP-MS. The mean δ 98/95 Mo SRM 3134 (NIST SRM 3134 Mo reference material; Lot No. 891307) composition of the IAPSO seawater reference material measured in this study was 2.00 ± 0.03‰ (2 s , n = 3), which is consistent with previously published values. The described procedure facilitated efficient and rapid Mo isotopic determination in various types of geological samples. en This link goes to a English section fr This link goes to a French section Une nouvelle méthode de pré-concentration est présentée pour la détermination des rapports isotopiques du Mo par spectrométrie de masse à source plasma et multi-collection (MC -ICP-MS) dans des échantillons géologiques. La méthode est basée sur la séparation du Mo par Chromatographie d'extraction en utilisant du N-benzoyle-N- phénylhydroxylamine (BPHA) supporté par une résine polymère d'ester acrylique microporeuse (Amberlite CG- 71). En optimisant la procédure, le Mo peut être simplement et efficacement séparé de la quasi-totalité des éléments de la matrice avec un seul passage à travers un petit volume de résine BPHA (0,5 ml). Cette technique de séparation et d'enrichissement du Mo est caractérisée par une grande sélectivité, une grande efficacité et une grande récupération de la colonne (~ 100%), et un faible total de la procédure de blanc (~ 0,18 ng). Un double spike Mo 100 -Mo 97 a été mélangé avec les échantillons avant la digestion et la séparation sur colonne, ce qui a permis la détermination du fractionnement isotopique naturel dépendant de la masse avec une reproductibilité de mesure de < 0,09 ‰ ( δ98/95 Mo, 2s) par MC -ICP-MS. La composition moyenne δ 98/95 Mo SRM 3134 (matériau de référence NIST SRM 3134 Mo; Lot n ° 891307) de l'eau de mer de référence IAPSO mesurée dans cette étude est de 2,00 ± 0,03 ‰ (2s, n = 3), ce qui est cohérent avec les valeurs précédemment publiées. La procédure décrite facilite une détermination efficace et rapide des rapports isotopiques du Mo dans divers types d’échantillons géologiques.
研究领域:
地球化学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
·
2020
·Vol. 36
·期 2
·429-438
·
IF 3.498
Ying Zhang,Jianguo Qu,Yan Chang,Yue Li
Phosphorus concentrations in water are usually determined using phosphomolybdenum blue (PMB) spectrophotometry. However, the measurement of extremely low phosphorus concentrations by this method is limited for various reasons. This work systematically developed a highly sensitive analytical method for the measurement of dissolved ultra-trace phosphorus by inductively coupled plasma mass spectrometry with methane mixed plasma (CH4-ICP-MS). We determined the optimal radio frequency (RF) power and verified the sensitizing effect of carbon-containing plasma, showing that the addition of 6.0 mL min−1 methane can significantly improve the sensitivity of phosphorus detection. There was no mass spectral interference in the determination of phosphorus in medium resolution mode. The species of phosphorus, dissolved organic carbon (DOC) concentrations ≤15.0 mg L−1, and salinity ≤3.4 had no effect on the determination of phosphorus. DOC concentrations >15.0 mg L−1 had some inhibitory effect on the determination, but microwave digestion eliminated the effect of organic matter with good reproducibility. Salinity levels >3.4 have an inhibitory effect on the determination and the samples need to be diluted or desalinated for accurate determination. The limit of detection (LOD) for the determination of phosphorus by CH4-ICP-MS is 7.3 ng L−1. The accuracy and precision of this method are 2.5% and 1.3%, respectively. The determination precision values for phosphorus in drinking water and in natural samples such as Arctic glacier meltwater, lake water, river water, seawater and rain water were all within 3.5%, and the spike recovery rates were 101.2–103.8%. The method developed here thus has a low LOD and high accuracy. Using the proposed method, ultra-trace phosphorus in low-phosphorus samples such as polar water can be directly measured, which simplifies the sample pretreatment process, and the sample is not easily contaminated by reagents.
研究领域:
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
GEOSTANDARDS AND GEOANALYTICAL RESEARCH
·
2020
·Vol. 44
·期 3
·617-627
·
IF 2.976
Ying Yu,Qian Zhao,Haolin Bao,Qing Mou,Zeming Shi,Youliang Chen,Ying Gao
With increasing use of bismuth in industry, a better understanding of its environmental behaviour is required, including an improved knowledge of its background concentration range in (non-saline) freshwaters. However, the poor analytical sensitivity of previous methods may lead to inaccurate measurement results for Bi 3+ in environmental samples. In this work, cobalt ion-assisted photochemical vapour generation (PVG) was developed for the detection of trace Bi with inductively coupled plasma-mass spectrometry (ICP-MS) measurement. The volatile species of Bi was found to be (CH 3 ) 3 Bi generated under UV irradiation in the presence of formic acid, acetic acid and Co 2+ . The major parameters potentially influencing the detection of Bi were investigated. Under optimised conditions, the limit of detection (3 s , n = 11) of the proposed method was 0.3 ng l −1 . The analytical sensitivity was enhanced about 70-fold for Bi 3+ compared with that using classic pneumatic nebulisation of ICP-MS. Furthermore, the proposed method showed better analytical sensitivity and anti-interference ability towards co-existing ions compared with ferric ion-assisted PVG systems. The accuracy of the proposed method was evaluated by analysis of environmental water samples and certified reference materials with satisfactory results.
研究领域:
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
GEOSTANDARDS AND GEOANALYTICAL RESEARCH
·
2018
·Vol. 42
·期 3
·309-318
·
IF 3.929
Tao He,Junyi Xie,Zhaochu Hu,Ting Liu,Wen Zhang,Haihong Chen,Yongsheng Liu,Keqing Zong,Ming Li
Bromine and iodine are important tracers for geochemical and environmental studies. In this study, a rapid acid digestion (HNO 3 + HF) with ammonia dilution for the simultaneous determination of bromine and iodine in soils and sediments using ICP-MS was developed. The recoveries of Br and I were controlled by the synergic effect of temperature and time. It took only 15 min at 140 °C for the complete recovery of Br and I in sediment (GSD-2) and soil (GSS-24) reference materials, which is a process that needs 2–6 h at 90 °C. A serious loss of Br and I was found at a higher digestion temperature of 190 °C. A 5% v/v NH 4 OH dilution effectively eliminated the memory effects and stabilised the signals of Br and I. Moreover, ammonia dilution also avoided the corrosiveness of HF on the sample introduction system and torch of ICP-MS. Tellurium is a more suitable internal standard element than In in the ammonia medium. To avoid the adsorption of residues of dissolution on Te, addition of Te should be carried out after centrifuging the solution. The developed method was successfully applied to determine Br and I in fifty-three Chinese soil and sediment reference materials. This simple method shows great potential for the rapid determination of Br and I in large batches of geological and environmental samples commonly analysed for mineral exploration and environmental geochemistry studies.
研究领域:
环境科学
·
地球化学
✓ 已验证
产品关联
DOI
高影响因子
Scientific Reports
·
2018
·Vol. 8
·期 1
·1-14
·
IF 4.122
Huang Wenli,Jiao Jie,Ru Mei,Bai Zhenqing,Yuan Honglin,Bao Zhian,Liang Zongsuo
Coptis chinensis Franch. is one of the most important medicinal plants globally. However, this species contains relatively high concentrations of chromium (Cr) which potentially detrimental to human health. It is important to understand Cr localization and speciation in order to evaluate its accumulation and transportation mechanisms and minimize Cr transfer to humans. As little previous work in this area has been carried out, we utilized synchrotron radiation microscopic X-ray fluorescence (SR-μXRF) and laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) to spatially locate Cr, X-ray absorption near-edge spectroscopy (XANES) to analyze Cr speciation, and inductively coupled plasma mass spectrometry (ICP-MS) to detect Cr subcellular concentration. Micromapping results showed that Cr was distributed predominantly within the vascular cylinder, the periderm and some outer cortex, and the cortex and some vascular bundles in root, rhizome, and petiole, respectively. XANES data showed that Cr(VI) can be reduced to Cr(III) when grown with Cr(VI), and yielded a novel conclusion that this plant contain elemental chromium. ICP-MS data showed that Cr was primarily compartmentalized in cell walls in all tissues. The new insights on Cr accumulation in C. chinensis Franch. provide a theoretical basis for the evaluation of Cr in other medicinal plants.
研究领域:
植物学
·
环境科学
·
药用植物研究
✓ 已验证
DOI
高影响因子
GEOSTANDARDS AND GEOANALYTICAL RESEARCH
·
2025
·
IF 3.4
Tao He,Hui Cao,Wang Lang,Zhaochu Hu,Zaicong Wang,Zongqi Zou,Wen Zhang,Haihong Chen,Yongsheng Liu
Silver is a powerful geochemical tracer in various geological processes (e.g., hydrothermal deposit formation and evolution of the terrestrial and Martian mantles). The measurement of the ultra-trace Ag (< 0.1 μg g -1 ) in geological samples by ICP-MS is often hindered due to serious polyatomic interferences arising from Zr, Nb and Y elements presented in samples. In this study, a simple and rapid ammonia coprecipitation method was developed to remove interference elements (Zr, Nb and Y) in NH 4 HF 2 digests for the determination of Ag mass fractions in geological materials by isotope dilution ICP-MS (ID-ICP-MS). The removal of interference elements (Zr, Nb and Y) in digestion solutions of geological materials was achieved using ammonia coprecipitation, effectively eliminating their polyatomic interferences. To compensate for the incomplete recovery of Ag during ammonia coprecipitation, isotope dilution calibration was chosen over internal standard calibration to achieve final accurate results. The limit of quantitation for Ag using the proposed method was 1.83 ng g -1 . The results obtained for Ag mass fractionation in nine international geological reference materials were in good agreement with the published values obtained by ID-ICP-MS and ICP-MS/MS. The proposed simple, rapid and practical analytical method for the determination of Ag mass fractions improves our understanding of the behaviour of silver in cosmochemistry and geochemistry studies.
研究领域:
地球化学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
MOLECULES
·
2022
·Vol. 27
·期 9
·2982
·
IF 4.927
Chao Ji,Jinyu Liu,Qin Zhang,Juan Li,Zhiqiang Wu,Xingyu Wang,Yuxin Xie,Jiangchao Zhao,Rui Shi,Xing Ma,Mohammad Rizwan Khan,Rosa Busquets,Xiahong He,Youyong Zhu,Shusheng Zhu,Wenjie Zheng
Panax notoginsengis an important functional health product, and has been used worldwide because of a wide range of pharmacological activities, of which the taproot is the main edible or medicinal part. However, the technologies for origin discrimination still need to be further studied. In this study, an ICP-MS/MS method for the accurate determination of 49 elements was established, whereby the instrumental detection limits (LODs) were between 0.0003 and 7.716 mg/kg, whereas the quantification limits (LOQs) were between 0.0011 and 25.7202 mg/kg, recovery of the method was in the range of 85.82% to 104.98%, and the relative standard deviations (RSDs) were lower than 10%. Based on the content of multi-element inP. notoginseng(total of 89 mixed samples), the discriminant models of origins and cultivation models were accurately determined by the neural networks (prediction accuracy was 0.9259 and area under ROC curve was 0.9750) and the support vector machine algorithm (both 1.0000), respectively. The discriminant models established in this study could be used to support transparency and traceability of supply chains ofP. notoginsengand thus avoid the fraud of geographic identification.Keywords:Panax notoginseng;ICP-MS/MS;multi-element;origin discrimination;cultivation model discrimination
研究领域:
植物学
·
药学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
·
2022
·Vol. 38
·期 2
·449-456
·
IF 4.351
Wengang Liu,Yuchen An,Qinyuan Qu,Pengfei Li,Lixin Zhang,Chaofeng Li,Shuang Wei,Hongying Zhou,Jiubin Chen
Barium (Ba) is a major element in many geological samples (e.g. barite/witherite-rich samples) and introduces serious oxide and hydroxide interferences during the analysis of rare earth elements (REEs) by ICP-MS. Hence, eliminating Ba interference is an indispensable step for accurate ICP-MS analysis of REEs. Though ion-exchange chromatography is widely used for REE purification, the tediousness, time consumption and high cost limit the application of this purification method. In this study, we developed a rapid and reliable separation method to eliminate Ba from geological samples for the precise measurement of REEs by ICP-MS. The new method was established based on the difference in solubility between Ba and REEs in concentrated nitric acid as barium nitrate (Ba(NO3)2) is almost insoluble, in contrast to REEs. The whole separation procedure could be completed in less than two hours and only consumed 1.5 mL 15 M nitric acid. The protocol resulted in acceptable procedural blanks (below 0.02 ng mL−1), quantitative recovery (96–103%) of REEs, and limited Ba content (0.37 ± 0.14 μg mL−1, (2SD, n = 50)) in the purified solution (50 mL), in which the interference effect could be eventually eliminated by mathematical correction during the ICP-MS analysis. The method was successfully applied to four natural barite-rich samples with BaSO4 content ranging from 18.87 wt% to 42.41 wt%. Overall, this accurate and rapid method shows great potential for the precise determination of the REE content in Ba-rich samples by ICP-MS.
研究领域:
分析化学
·
地球化学
✓ 已验证
产品关联
DOI
高影响因子
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
·
2019
·Vol. 103
·期 3
·1475-1483
·
IF 3.67
Liu Zihui,Xue Aifang,Chen Hao,Li Shengqing
Time-resolved inductively coupled plasma mass spectrometry (ICP-MS) for studying cellular heterogeneity or detecting metals in single cells draws increasing attention in the recent years. Considering the full width of a single-cell event is about 0.5–0.9 ms, dependent on the duration of the ion plume generation in typical ICP condition, dwell time shorter than the transient event was suggested for fully profiling it. Herein we investigated the effect of dwell time (0.1–10.0 ms) on the signal profiles of single-cell events, signal-to-background ratio, duty cycle of detection, the limit of detection, and the ability of cell counting by the time-resolved ICP-MS, using yeast ( Saccharomyces cerevisiae ) cells as example. Two calibration equations with respect to the length of dwell time (0.1 ms or 5.0 ms), simply using dissolved metal standard solutions, were constructed and successfully applied to the determination of K, Mg, Zn, Mn, and Cu in single yeast cells. The limit of detection (LOD, fg per cell) obtained at dwell time 0.1 ms was 1.68 (K), 0.29 (Mg), 0.17 (Zn), 0.01 (Mn), and 0.02 (Cu) for single-cell analysis of yeast cells; the LOD (fg per cell) at 5.0 ms was 80.0 (K), 10.3 (Mg), 1.6 (Zn), 0. 14 (Mn), and 0.24 (Cu), respectively. The results showed that a short dwell time leading to high signal-to-background ratio and low LOD was a prerequisite for the quantitative analysis of ultra-trace content of metals in single cells.
研究领域:
分析化学
·
生物化学
✓ 已验证
DOI
高影响因子
TALANTA
·
2018
·
IF 4.244
Chao Wang,Man He,Beibei Chen,Bin Hu
In this work, ethylenediamine modified poly(glycidyl methacrylate-ethylene dimethacrylate)(poly(GMA-EDMA-NH 2 )) was prepared for highly selective extraction of Se(VI) with high adsorption capacity of 0.825 mg m −1 (530 µm i.d.). Based on it, a novel method of polymer monolithic capillary microextraction (CME) on-line coupling with inductively coupled plasma-mass spectrometry (ICP-MS) was developed for the determination of inorganic selenium species (Se(IV)/Se(VI)) in natural waters. Under the optimized conditions, the analytical performance of the proposed on-line CME-ICP-MS method was evaluated for Se(VI). The limit of detection for Se(VI) was 14.2 ng L −1 , and the enrichment factor was 50-fold with the sample throughput of 5 h −1 . For Se(IV), the concentration was obtained by subtracting Se(VI) from the total Se(VI) obtained by the proposed method after oxidation of Se(IV) to Se(VI). The accuracy of the method was validated by the analysis of a Certified Reference Materials of GBW(E)080395. The proposed method was applied for the analysis of inorganic selenium species in natural waters with good recoveries. The developed method of monolithic CME-ICP-MS is sensitive, simple and rapid for the analysis of inorganic selenium species in natural waters.
研究领域:
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
·
2022
·Vol. 38
·期 1
·156-165
·
IF 4.351
Xiuhong Liao,Wen Zhang,Tao Yang,Zhaochu Hu,Tao Luo,Xianli Zeng,Lian Zhou
Rare earth elements (REEs) in porewater can be useful proxies in the studies of marine geochemistry. The main challenges for the determination of REEs in porewater samples from marine sediments lie in three aspects—low concentration, high salinity, and limited sample sizes (usually only a few millilitres). In this study, a method based on laser ablation (LA) solution sampling ICP-MS for REEs analysis of small volumes (2–4 mL) of porewater is established. With the help of matrix removal and REEs preconcentration from natural liquids by a miniaturized Fe(OH)3 co-precipitation method, a high enrichment factor (10–20 fold) was achieved with only 2 mL of the original liquid, which was preconcentrated to be as small as 100–200 μL. Ultratrace (sub-pg mL−1) analysis was realized through the use of high laser ablation pulse frequency (up to 250 Hz) and based on the high transport efficiency of aerosol particles by the LA system. Due to the almost “dry” ICP condition generated by LA and nitrogen addition (5 mL min−1) to the plasma, the CeO+/Ce+ ratio was reduced to approximately 0.05%, and the total yields of BaO+ and BaOH+ ions were reduced to 0.003%, which means that the potential biases induced by oxide and hydroxide interferences could be negligible. Method validation was achieved through the analysis of the seawater reference material NASS-7 and a spike recovery test with quantitative recoveries of 94–101% for REEs. The application results of porewater samples characterized by no or slight Ce anomalies together with significantly positive Eu anomalies may be indicative of highly reducing and neutral to basic pH conditions. Reagents consumed by the LA-ICP-MS method were significantly reduced, making it a more environment-friendly method. Moreover, the simplicity in sample preparation and lack of need for special reagents or devices give the proposed method great potential for wide applications in the determination of REEs in natural water samples.
研究领域:
海洋化学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）