OPTICAL MATERIALS
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2025
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IF 4.2
Pei Zhang,Mengmeng Li,Yibo Zheng,Linjiao Ren,Zirui Qin,Qingfang Zhang,Rubin Qi,Jitao Zhang,Liying Jiang,Dongke Li
The isoreticular metal organic frameworks-3 (IRMOF-3)/non-stoichiometric thiol-ene (OSTE) and 2-aminoterephthalic acid (BDC-NH 2 )/OSTE composites were synthesized via a photo-induced click reaction. Interestingly, through polymerization with OSTE, both the fluorescence lifetime and intensity of IRMOF-3 increased. Moreover, its two lifetimes merged into one, which could be ascribed to the inhibition of the dynamic non-radiative quenching process by the OSTE network. In contrast, the ligand maintained a single lifetime with only minor changes. The dilution effect of the thiol-ene mixed solution could effectively reduce the static photo-induced electron transfer process between the ligand and toluene molecules. After the post-synthetic polymerization (PSP) treatment, the photoluminescence quantum yield (PLQY) of IRMOF-3 was increased from 7.2 % (in toluene) to 42.3 %, and that of the pure BDC-NH 2 ligand was significantly enhanced from 1.8 % (in toluene) to 76.0 %. Moreover, when a commercially available 370-nm light-emitting diode (LED) chip was individually encapsulated by the two composites, it could emit intense indigo light. This rapid PSP treatment via the OSTE polymer holds promise for application in other excellent luminescent MOFs.
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高影响因子
ANALYTICA CHIMICA ACTA
·
2023
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IF 6.2
Yue Pan,Shan Xu,Zhouping Wang,Caiyun Jiang,Xiaoyuan Ma
Background Histamine is a kind of biogenic amine with strong toxicity and potential carcinogenicity . Many traditional methods of detecting histamine have the disadvantages of cumbersome detection steps, expensive equipment, and high professional requirements for staff. In contrast, SERS has become the preferred method for quantitative analysis of histamine because of rich fingerprint information, rapidity and economy. However, most of SERS substrates still have technical problems, such as poor stability, low sample collection rate, and detection efficiency. Therefore, there is a great need for new strategies to develop high-performance SERS substrates based sensors. Results In our study, a sensitive SERS aptasensor for the detection of histamine was synthesized. The assembly was formed between IRMOF-3@Au/PDMS (flexible SERS substrate) and AuNR-DTNB@Ag-HA apt (Raman signal probe with both the target capture ability) via π-π stacking interaction from HA aptamer and IRMOF-3. Consequently, the SERS signal of the assembly derived from DTNB reached highest due to the synergistic enhancement effect by AuNR@Ag and IRMOF-3@Au. Meanwhile, HA aptamer can specifically capture histamine, therefore histamine addition competitively bound to the probe, leading to a corresponding decrease in the DTNB signal value on the SERS substrate. The SERS intensity at 1331 cm −1 presented a good linear relationship towards the logarithmic value of histamine concentrations ranging from 0.0001 mg/L to 400 mg/L (R 2 = 0.990) with the LOD of 3.6 × 10 −5 mg/L. Furthermore, the application in wine samples demonstrated the accuracy and applicability of the developed sensor. Significance This method effectively improves substrate stability, detection sensitivity and signal response immediacy to amplify the SERS sensor, thus satisfying the histamine detection requirements of various systems. According to this aptasensor design, our strategy can be extended to create other MOF-based SERS substrates for accurately detecting relative targets to ensure food safety.
研究领域:
分析化学
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食品安全检测
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生物传感器
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PubMed
高影响因子
DALTON TRANSACTIONS
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2020
·Vol. 49
·期 27
·9369-9376
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IF 4.174
Xin Zheng,Keliang Jiang,Linlin Zhang,Cheng Wang
N-doped three-dimensional carbon nanostructured materials were obtained by calcinating hierarchical porous IRMOF-3 materials, and were fabricated in the presence of citric acid as a modulator via the conventional synthetic protocol, at 900 °C in an Ar atmosphere. The resultant carbon materials were used as anode materials for lithium ion batteries, and exhibited excellent lithium storage capacity and cycling stability and maintained a capacity of about 555 mA h g−1 at the current density of 0.2 A g−1 after 100 cycles.
研究领域:
材料科学
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能源存储与转换
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高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2025
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IF 3.8
Zhang Shirong,Tan Yuxin,Liu Yilei,Li Yafei,Li Jishun,Zhang Shenglan,Pan Hongcheng
Quantum dots (QDs) have emerged as highly sensitive fluorescent markers for lateral flow immunoassays (LFIAs) due to their excellent fluorescence brightness and photostability. The incorporation of multiple QDs onto a carrier can further enhance detection sensitivity. However, traditional carriers such as polystyrene, while commercially successful, involve complex preparation processes and rely on organic solvents, which can lead to fluorescence quenching and adversely affect detection performance. In this study, we selected isoreticular metal–organic framework-3 (IRMOF-3), characterized by its porous structure, high surface area, and abundant amine functional groups, as the carrier. We synthesized IRMOF-3@CdSe/ZnS composite nanoparticles with an average diameter of 378 ± 46 nm by coupling carboxyl-modified CdSe/ZnS QDs to the IRMOF-3 surface through an aqueous synthesis method. These nanocomposites efficiently loaded a high density of QDs without aggregation, thereby maintaining strong fluorescence intensity. Moreover, the abundant amino and carboxyl groups on their surfaces facilitate efficient antibody conjugation, and the nanoparticles retain excellent water dispersibility after labeling. Utilizing IRMOF-3@CdSe/ZnS composite nanoparticles as immunomarkers, we developed a novel fluorescent LFIA for the detection of interleukin-6 (IL-6), a biomarker associated with various inflammatory and autoimmune diseases. The method achieved a limit of detection for IL-6 as low as 8.6 pg/mL, with relative standard deviations ranging from 2.73% to 6.14% and spiking recoveries between 96.4% and 110.8%. Passing-Bablok regression analysis demonstrated good consistency between our method and commercially available immunochromatography assays. The IRMOF-3@CdSe/ZnS composite nanoparticles, as a novel fluorescent label, exhibit considerable potential for applications in biomedical detection. Graphical abstract
研究领域:
分析化学
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生物化学
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纳米技术
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免疫学
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生物医学工程
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材料科学
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PubMed
高影响因子
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