Materials Science & Engineering C-Materials for Biological Applications
·
2021
·
IF 7.328
Yongmei Ge,Kui Wang,Huili Li,Ye Tian,Yutong Wu,Zhaowei Lin,Yangyang Lin,Yansong Wang,Jiarong Zhang,Bin Tang
Bone pain is the primary problem for patients with osteoporosis. Ketoprofen is clinically used to treat osteoporotic pain, while long-term oral administration of ketoprofen can cause some side effects. In addition, osteoporosis is also accompanied by bone mass loss and inflammation. In this study, we designed a multifunctional drug (Ket@Mg-MOF-74) adopted Mg-MOF-74 to load ketoprofen to treat osteoporotic pain, bone loss and inflammation comprehensively. Mg-MOF-74 was prepared, and the physicochemical characterization proved that it had excellent physical and chemical stability. Ket@Mg-MOF-74 was synthesized by post-synthetic modification method and a high loading rate of ketoprofen was confirmed. Drug release and ion release experiments indicated Ket@Mg-MOF-74 had a good controlled release of ketoprofen and Mg in solution. Cell experiments in vitro proved the compound drug could significantly reduce the expression of pain-related genes of cyclooxygenase 2 (COX2), obviously up-regulated the expression of osteogenic cytokines and remarkably down-regulated the secretion of pro-inflammatory factors. Therefore, Ket@Mg-MOF-74 is believed a promising painkiller for osteoporotic bone pain, with the function of anti-inflammatory and promoting bone formation.
研究领域:
药理学
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材料科学
·
骨生物学
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DOI
PubMed
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2023
·Vol. 47
·期 40
·18591-18602
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IF 3.3
B. Wang,S. Peng,H. Chen,H. Ren,Y. Yan,Q. Zhang
Degradable bone cement is widely used in the repair and treatment of bone defects due to its good plasticity and degradability and is also a good matrix for loading functional reagents or drugs. However, the release profile of drugs in bone cement will directly determine the performance of the bone cement. Coating drugs with natural polymer-based hydrogels is a common method of sustained drug release. Therefore, the magnesium gallate metal organic framework (Mg-MOF) with antibacterial properties is coated with oxidized dextran/gelatin (OD/Gel) and doped into the composite cement composed of calcium sulfate, calcium citrate and dicalcium phosphate anhydrous. The doping of OD/Gel@Mg-MOF has little effect on the microstructure and curing properties of the composite cement, but the mechanical strength of the cement increases from 27.20 MPa to 32.12 MPa. The controlled release of Mg-MOF can be sustainable for over 10 days, and OD/Gel@Mg-MOF bone cements exhibit excellent antibacterial properties against Staphylococcus aureus and Escherichia coli. Simultaneously, the composite bone cement can promote cell proliferation and osteogenic differentiation, alkaline phosphatase activity and calcium nodule deposition.
研究领域:
材料科学
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生物医学工程
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药学
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DOI
高影响因子
JOURNAL OF SOLID STATE CHEMISTRY
·
2024
·
IF 3.2
Shilin Diao,Mengfang Li,Xuan Liu,Yujia Liu,Qingjin Shang,Yewei Xu
A hybrid material , Ca/Mg-MOF/polyamidoxime (Ca/Mg-MOF/PAO), was synthesized and tested for uranium(VI) uptake in solution. The structure and performance of Ca/Mg-MOF/PAO were comprehensively investigated. Adsorption experiments demonstrated that Ca/Mg-MOF/PAO exhibited an extraordinary saturation capacity of 579.5 mg/g for uranium (VI) at pH = 8, surpassing that of most other adsorbents. The adsorption process of Ca/Mg-MOF/PAO on uranium (VI) conformed to Langmuir and PSO models, suggesting chemical rate control and monolayer adsorption, respectively. Furthermore, Ca/Mg-MOF/PAO displayed excellent adsorption-desorption recovery performance for uranium (VI). Its high adsorption capacity and efficient recoverability position Ca/Mg-MOF/PAO as a material with great potential for extracting uranium (VI) from aqueous media.
研究领域:
材料科学
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环境科学
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产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2021
·
IF 7.312
Chun-Ping Li,Ya-Qi Wu,Fei-Yang Zhang,Li-Xin Gao,Da-Quan Zhang,Zhong-Xun An
Carbon materials with suitable pore size distribution, high specific surface area and good wettability are crucial for the capacitive deionization (CDI) electrode. Herein, the Mg-MOF-74 derived carbon (MMCK) is prepared by solvothermal synthesis, carbonization, and potassium hydroxide (KOH) activation method. The MMCK has super hydrophilicity and rich hierarchical porous structure composed of micropores, mesopores and macropores. The capacitive deionization of MMCK is investigated in NaCl aqueous solution. The MMCK has high oxygen doping amount, and has a high electrosorption capacity (16.82 mg·g −1 ) for 500 mg·L −1 NaCl. This indicates that MMCK is novel and potential material for capacitive deionization.
研究领域:
材料科学
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环境工程
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DOI
高影响因子
AICHE JOURNAL
·
2020
·Vol. 66
·期 11
·e16645
·
IF 3.519
Meng-Meng Jin,Yu-Xia Li,Chen Gu,Xiao-Qin Liu,Lin-Bing Sun
Due to the excellent adsorption capacity on CO 2 , Mg-MOF-74 is highly potential for carbon capture. However, the practical application is seriously hindered by the poor hydrolytic stability of Mg-MOF-74 even towards trace of moisture. Here we report a strategy by adjusting the microenvironment of Mg-MOF-74 from hydrophilic to superhydrophobic by coating polydimethylsiloxane (PDS, yielding M74@P), which markedly enhances the hydrolytic stability. Mg-MOF-74 is degraded obviously upon exposure to humid atmosphere (75% relative humidity) for 7 days, while M74@P retains its structure well even after 1 year. The dynamic breakthrough results show that the optimized M74@P sample can capture 6.65 mmol g −1 CO 2 from wet CO 2 /N 2 mixtures after 100 cycles, which is superior to Mg-MOF-74 (1.17 mmol g − 1 ) and most reported adsorbents under comparable conditions (continuous flow adsorption from wet gases). The excellent adsorption capacity and hydrolytic stability make the present adsorbents highly promising for practical applications in carbon capture.
研究领域:
化学工程
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材料科学
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环境科学
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2026
·
IF 12.5
Lin-Yuan Xiao,Chao-Yue Zhuo,Xiao-Nan Qin,Yue-Fei Zhang,Ziyi Li,Xiao Luo,Xiangjun Luo,Zhiwu Liang
Aminosilane concentration tunes Mg-MOF-74 structural evolution and porosity. • CO 2 adsorption exhibits high uptake at both ambient and high pressures. • The mechanism of how defects and amine groups synergistically enhance CO 2 capture capacity was studied. In this study, we report a rational design and synthesis of hierarchically porous 5/PA2-Mg-MOF-74@APTES with high CO 2 capacity through propionic acid (PA) modulation and amine functionalization (APTES). Characterization results confirmed that an optimized PA concentration effectively induced mesopore formation and exposed more unsaturated Mg 2+ sites, thereby generating hierarchical porosity, while subsequent grafting of APTES successfully introduced amino functional groups This combined strategy leverages both defect engineering and chemical functionalization, synergistically promoting CO 2 adsorption. Performance evaluations revealed that the optimal adsorbent 5/PA2-Mg-MOF-74@APTES(1:1), achieved a CO 2 uptake of 4.91 mmol·g −1 at atmospheric pressure (1 bar) and a remarkable uptake of 17.38 mmol·g −1 at high pressure (15 bar) with significantly improved CO 2 /CH 4 selectivity. This work explores a synergistic enhancement mechanism of CO 2 adsorption from the interplay of defect engineering and amine functionalization conducted by experimental characterization and theoretical calculations, which provides a novel strategy for the design and fabrication of high-efficiency CO 2 adsorbents suitable for diverse pressure applications.
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Muhammad Junaid Khan,Muhammad Rehan Islam,Farooq Hafeez,Chunyan He,Jun Zhang,Yunlei Xianyu
The proliferation of pathogenic microorganisms is a significant cause of food spoilage, resulting in substantial economic losses and public health risks. To ensure food safety and extend shelf life, packaging must not only maintain product integrity but also prevent contamination by multidrug-resistant (MDR) pathogens such as Escherichia coli ( E. coli ), Listeria monocytogenes ( Listeria ), and Candida albicans ( C. albicans ). In this study, we developed a multifunctional nanocomposite (Mg-MOF-74@CA/CNF) by integrating magnesium-based metal–organic framework (Mg-MOF-74), carvacrol (CA), and chitin nanofibers (CNF). This nanocomposite was subsequently incorporated into a polyvinyl alcohol (PVA) matrix to fabricate the final film (Mg-MOF-74@CA/CNF/PVA). The resulting film demonstrated excellent antimicrobial activity, achieving up to 98 % inhibition of MDR pathogens through reactive oxygen species (ROS) generation and disruption of microbial membranes. In addition, the film exhibited improved thermal stability, enhanced tensile strength, and superior barrier properties against oxygen and water vapor. Application tests on cherry, cauliflower, and chicken confirmed significant reductions in microbial growth and weight loss, alongside prolonged shelf life while maintaining product quality. These findings highlight Mg-MOF-74@CA/CNF/PVA as a sustainable and effective alternative to conventional packaging materials, offering both food preservation and enhanced safety.
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DOI
高影响因子
NANO
·
2024
·
IF 1
Xiaoying Lin,Xiuchun Fan,Lifang Xu,Hao Lin,Qinhua Zhong
A porous carbon material (Mg-MOF-C) was prepared by carbonization in the N 2 atmosphere using Mg-MOF-74 as the precursor. Physicochemical properties of Mg-MOF-C materials were well characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FIRT), Thermogravimetric analyzer (TG), transmission electron microscope (TEM), energy dispersive spectrometer (EDS), N 2 adsorption/desorption isotherms (BET) and EDS. The adsorption properties of the products were studied Mg-MOF-C has a high specific surface area of up to 1739.29 m 2 /g, and the pore volume of micropores was 0.98 m 3 /g. Besides, 95% of the first adsorption is retained after five cycles. The adsorption processes agreed well with the pseudo-second-order kinetic model and Langmuir isotherm model.
研究领域:
材料科学
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环境化学
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吸附技术
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金属有机框架材料（MOFs）
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碳材料
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DOI
高影响因子
RARE METALS
·
2025
·Vol. 44
·期 4
·2805-2814
·
IF 11
Chen Xu-Dong,Zhao Si,Feng Xin-Fu,Huang Jin,Wang Yan,Qiu Zhen-Chun,Wang Jian-Biao,Huang Yi-Yin,Zheng Li-Tuo,Wei Ming-Deng,Hong Zhen-Sheng
Graphic abstract
研究领域:
材料科学
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电化学
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能源存储
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固态电池
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纳米材料
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界面化学
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产品关联
DOI
高影响因子
DESALINATION
·
2025
·
IF 9.8
Xiaosong Zhang,Jiajia An,Daquan Zhang
Fluoride contamination has become a global public health problem due to its adverse health effects. The search for efficient and environmentally friendly fluoride removal technology is an urgent issue. Capacitive deionization (CDI) technology has attracted much attention because of its high efficiency, easy operation and environmental friendliness. Electrode materials are crucial for CDI systems. Herein, Mg-MOF-derived dendritic carbon materials (MMCNF) are successfully grown in situ on lignin nanofibers via solvothermal synthesis. Due to the high specific surface area of Mg-MOF and the structural stability of lignin nanofibers, it has a high specific capacitance of 158 F·g −1 at a current density of 1 A·g −1 . And the capacitance retention of 93.13 % is obtained after 5000 charge/discharge cycles. The CDI unit equipped with MMCNF electrodes effectively reduced the fluoride ion concentration to 1.21 mg·L −1 in a 10 mg·L −1 simulated fluoridated wastewater, exhibiting a maximum adsorption capacity of 20.64 mg·g −1 . It is lower than the drinking water standard of 1.5 mg·L −1 set by the World Health Organization. This work offers new electrode materials and technological options for the removal of fluoride ions from wastewater in the future.
研究领域:
环境科学
·
材料科学
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Chaoying Zhang,Qian Jia,Guoqiang Li,Feng Li,Haitao Cui,Congming Li,Lei Li
An ultramicroporous variant of Mg-MOF-74 is synthesized through a mixed-linker strategy incorporating ethylenediaminetetraacetic acid (EDTA) as exotic linker. • An exclusive H 2 O adsorption site is created based on the uncoordinated oxygen atoms of EDTA. • The hydrogen-bonding network within EDTA-modified frameworks enhances CO 2 adsorption by 14.3 % via the formation of carbonates. • Incorporating EDTA molecules increases the CO 2 /N 2 selectivity by a factor of 2.28 compared to pristine Mg-MOF-74. • The EDTA-modified Mg-MOF-74 outperforms the pristine Mg-MOF-74 with a two-fold enhancement in CO 2 uptake under humid conditions. Mg-MOF-74 ([Mg 2 (DOBDC)]) represents a high-performance solid adsorbent for carbon capture, however, its CO 2 uptake decreases significantly under humid flue gas conditions due to competitive adsorption between H 2 O and CO 2 molecules. Herein, a mixed-linker modification strategy is employed by integrating ethylenediaminetetraacetic acid (EDTA) into the Mg-MOF-74 framework. This approach preserves the original one-dimensional pore structure while altering the coordination environment of Mg 2+ sites, reducing their coordination number to five. The resulting structure with uncoordinated oxygen atoms from EDTA serves as exclusive adsorption centers for H 2 O thereby protecting the CO 2 adsorption capacity. The optimized MOFs exhibits a high CO 2 adsorption capacity (6.4 mmol/g, at 1 bar) and outstanding CO 2 /N 2 selectivity (346). In humid CO 2 /N 2 (15:85, v:v, at 314 K, RH% = 86%) breakthrough experiment, the EDTA-modified frameworks maintain stable CO 2 uptake (3.92 mmol/g), consistent with dry performance, whereas the pristine Mg-MOF-74 shows a great reduction (2 mmol/g). In-situ FTIR further reveals that the incorporation of EDTA facilitates the formation of hydrogen bonding and carbonate species, synergistically enhancing the moisture resistance of MOF materials. Moreover, the modified material retains stable breakthrough times over six consecutive adsorption-desorption cycles under high-humidity conditions, demonstrating its great potential for scalable industrial carbon capture applications.
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 13.2
Menghuan Wu,Yifang Zhang,Zhiping Xu,Yuqi He,Jialei Wang,Tian Xie,Shuduan Deng,Lidan Zhang,Gang Zhu
Metal–organic frameworks often lose CO 2 capacity in hot, humid flue gas because H 2 O competes for open metal sites (OMSs). Here we report a dual-stabilized, wood-based adsorbent in which Mg-MOF-74 is grown on an aminated wood sponge and overcoated with an ultrathin polydimethylsiloxane (PDMS) layer, coupling support immobilization with interfacial hydrophobization while preserving access to OMSs. Under flue-gas-relevant conditions (323 K, 50% RH), the material delivers a CO 2 uptake of 1.68 mmol·g −1 (≈89% of its dry-state capacity) and an IAST CO 2 /N 2 selectivity of 144 for a 50/50 mixture at 323 K. Humid-gas breakthrough tests confirm robust separation performance. Density functional theory (DFT) calculations attribute the humidity tolerance and selectivity to the synergy between accessible OMSs and PDMS-mediated interfacial polarity, without increasing the isosteric heat of adsorption, thereby enabling energy-efficient regeneration. The framework retains its crystallinity after 30 days of water immersion, and a techno-economic estimate projects a material cost of approximately US$10.36 kg −1 at a 1000 t·yr −1 scale. This scalable architecture reconciles capacity, selectivity, humidity resistance, and cost for post-combustion CO 2 capture.
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DOI
高影响因子
危险品化学品经营许可证（带存储）