Journal of Materials Chemistry C
·
2022
·Vol. 10
·期 21
·8356-8363
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IF 8.067
Ye Li,Miaoling Cai,Mengling Shen,Yuting Cai,Rong-Jun Xie
The stability of perovskite nanocrystals (NCs) is greatly limited due to highly dynamic binding of ligands, which hinders their applications in optoelectronic devices. In this paper, a new ligand strategy was employed to prepare CsPbBr3 NCs via a facile room temperature (RT) ligand-assisted reprecipitation (LARP) method, where N1.N2-didodecyl-N1.N1.N2.N2-tetramethylethane-1.2-diaminium bromide (DTDB) as the sole capping ligand and an additional Br resource was used. Compared to other ligands with one coordinating group, this class of bidentate ligand can be tightly anchored to the surface of NCs with double N+ sites. The as-synthesized DTDB-CsPbBr3 NCs exhibited a high photoluminescence quantum yield (PLQY) of 92.3% and also showed a superior colloidal stability even under intense purification for up to ten cycles. Compared to the dodecyltrimethyl ammonium bromide (DTAB) ligand capped-CsPbBr3 NCs, the DTDB-CsPbBr3 NCs display obviously enhanced stability to light, heat and water. X-ray photoelectron spectroscopy (XPS) results revealed that the DTDB-CsPbBr3 NCs have a Br− rich surface, which accounts for the high stability and PLQY. Hence, DTDB is a promising ligand to prepare perovskite NCs with higher optical performance.
研究领域:
材料科学
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纳米技术
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光电技术
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高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2024
·
IF 8.1
Yu Wang,Ailing Pan,Yuhua Ma,Hong Du
Single - atom catalysts (SACs) have attracted extensive attention because of their high atomic utilization and superior catalytic activity. Herein, single - atom Co has anchored on the β - ketoenamine - linked covalent organic framework (Tp-Tta COF) pores and used for remarkable photocatalytic hydrogen(H 2 ) production under Ultraviolet – Visible light (UV – Vis light) irradiation. The single - atom Co is visualized by the aberration - corrected high - angle annular dark - field scanning transmission electron microscopy (AC HAADF - STEM), and the C 3 – Co – N 1 coordination structure is demonstrated by X - ray absorption fine structure (XAFS) measurements. The modified Co 0.4 -SAC/Tp-Tta COF shows a high photocatalytic H 2 production of 1798.5 μmol g −1 h −1 and the Apparent quantum yield(AQY) is 3.02% at 420 nm. The improvement of the activity and stability of the photocatalyst is mainly attributed to the incorporation of Co single-atom that boosts the separation efficiency of photogenerated electron-hole pair and provides well - dispersed active sites. This study provides valuable insights into the development of UV–Vis light-responsive photocatalysts at the atomic level.
研究领域:
材料科学
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催化化学
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能源科学
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DOI
高影响因子
PLoS One
·
2026
·Vol. 21
·期 1
·e0339776
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IF 2.6
Keming Ying,Han Xue,Shenheng Du,Xin Wang,Xiaoyun Lei
N1,N12-diacetylspermine (DiAcSpm), a promising biomarker for cancer diagnosis, presents significant quantification challenges due to the structural homology within the polyamine family. To address this issue, we engineered a molecularly imprinted monolithic (MIM) column functionalized with biomimetic phosphorylcholine (PC) as functional monomer for the selective recognition of DiAcSpm in human urine. The zwitterionic polymer was synthesized via thermally initiated polymerization, with its morphology and pore architecture characterized through scanning electron microscopy (SEM) and brunauer-emmett-teller (BET) analysis. After optimizing capillary microextraction (CME) parameters, the MIM demonstrated a broad linear response (10–500 μM), a low detection limit (3.3 μM, S/N = 3), and high recoveries (76.8–91.2%) when coupled with HPLC-UV analysis. The biomimetic PC-based recognition significantly improved selectivity against key structural analogs, such as spermine, in complex biological matrices. This study underscores the potential of zwitterionic-based MIMs as a robust and efficient platform for the sensitive and selective monitoring of acetylated polyamines in clinical settings.
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PubMed
高影响因子
RSC Advances
·
2017
·Vol. 7
·期 83
·52812-52821
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IF 3.108
Jinkai Hao,Xueqiang Gao,Yongyi Jiang,Feng Xie,Zhigang Shao,Baolian Yi
Novel N1, C4, C5-substituted imidazolium-based crosslinked anion exchange membranes (AEMs) are prepared by the incorporation of polybenzimidazole (PBI) into the poly(vinylbenzyl chloride) (PVBC) matrix. 1-Butyl-4,5-dimethyl-imidazole (BDIm) with methyl substituents at C4, C5 and long side alkyl substituents at N1 is firstly synthesized to enhance the stability of AEMs by steric hindrance and hyperconjugative effects and characterized by 1H NMR. The effects of crosslinking density of AEMs on the hydroxide conductivity, swelling ratio, thermal stability, oxidative and alkaline stability are evaluated in detail for fuel cell applications. The results reveal that the crosslinking structure between PVBC and PBI plays a vital role in achieving both good mechanical properties and low swelling ratio. Notably, the AEM containing 66.7% PVBC has the highest ionic conductivity of 16.1 mS cm−1 at 20 °C with an IEC of 2.1 mmol g−1. Meanwhile, the AEMs also exhibit excellent oxidative stability in Fenton's reagent for 200 h and alkaline stability in 1 mol L−1 KOH at 60 °C for 480 h. Furthermore, the peak power density of an H2/O2 single fuel cell is up to 54 mW cm−2.
研究领域:
材料科学
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能源工程
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DOI
高影响因子
MOLECULES
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2019
·Vol. 24
·期 5
·891
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IF 3.06
Ye Liu,Jiaqi Liu,Renmei Zhang,Yan Guo,Hongbo Wang,Qingguo Meng,Yuan Sun,Zongliang Liu
3,4-dihydropyrimidin-2(1H)-one compounds (DHPMs) possess extensive biological activities and are mainly prepared via Biginelli reaction and N-alkylation. In the present study, selective alkylation of N1was investigated by using tetrabutylammonium hydroxide. In vitro cytotoxicity study on all synthesized compounds demonstrated that introduction of the aryl chain in the R3as well as the low electron-donating group in the R1of DHPMs contributed to the anti-proliferative potency. A larger value of the partition coefficient (Log P) and suitable polar surface area (PSA) values were both found to be important in order to maintain the antitumor activity. The results from in vivo study indicated the great potential of compound3dto serve as a lead compound for novel anti-tumor drugs to treat glioma. Pharmacophore study regarding the structure-activity relations of DHPMs were also conducted. Our results here could provide a guide for the design of novel bioactive 3,4-dihydropyrimidin-2(1H)-one compounds.Keywords:3,4-dihydropyrimidin-2(1H)-ones;N1-alkylation;structure-activity relationship;in vivo experiments;anticancer activities
研究领域:
药物化学
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药理学
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癌症研究
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PubMed
高影响因子
Sustainability
·
2023
·Vol. 15
·期 7
·6061
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IF 3.9
Xiaona Wang,Haishu Sun,Yonglin Wang,Fangxia Wang,Wenbin Zhu,Chuanfu Wu,Qunhui Wang,Ming Gao
This study investigated the feasibility of direct butanol production from starchy food waste (without saccharification and nutrient supplementation). First,Clostridium saccharoperbutylacetonicumN1-4 was selected as an efficient starch-utilizing clostridia, and amylose was used by the strain more readily than amylopectin for solvent production. Furthermore, direct fermentation avoided substrate inhibition due to saccharification and produced 12.1 g/L of butanol at a production rate of 0.705 g/L/h and a yield of 0.402 C-mol/C-mol with a solid–liquid ratio of 1:1 (w/v). At a solid–liquid ratio of 1:2 (w/v), the maximum butanol production rate in the direct mode was 2.05 times higher than that in the saccharified mode. Elemental analysis demonstrated that the food waste analyzed was rich in trace elements and, hence, exogenous nutrient supplementation was unnecessary. Collectively, direct butanol production from food waste could function as a low-cost, highly efficient, and simple fermentative process, which is a promising strategy for food waste disposal.Keywords:butanol production;food waste;direct fermentation;no nutrient supplementation;Clostridium saccharoperbutylacetonicum
研究领域:
微生物学
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环境科学
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生物技术
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高影响因子
Sustainable Energy & Fuels
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2023
·Vol. 7
·期 9
·2153-2162
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IF 5.6
Xiujie Chang,Xueshu Li,Shujin Ge,Guanglei Tan,Zhaodong Wang,Yanfei Ma,Lin Niu,Qiuhong Li
The reduction and harmless treatment of oily sludge is a challenging task. Microemulsion cleaning has been demonstrated to be an effective method to treat hazardous oily sludge. In this research, based on the low toxicity and high polarity of quaternary ammonium ionic liquids, cetyl-(2-hydroxyethyl)-dimethylammonium chlorine ([N1,1,16EtOH]Cl) synthesized from N,N-dimethylethanolamine and 1-chlorohexadecane was chosen as a surfactant to prepare IL microemulsions, which could be used for effective treatment of oily sludge. The influencing factors of microemulsion treatment conditions (stirring time, stirring speed, temperature and centrifugal speed) were explored, and the residual oil rate of oily sludge was reduced to 1.03% under optimal treatment conditions. The sludge after centrifugation was characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), contact angle measurement and thermogravimetry (TG). Additionally, the simulation and calculation proved the strongest interaction between [N1,1,16EtOH]Cl and asphaltenes, which made it better for understanding the oil removal mechanism using [N1,1,16EtOH]Cl microemulsions and provided theoretical guidance for the efficient treatment of oily sludge.
研究领域:
环境科学
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化学工程
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材料科学
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高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
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2026
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IF 19.7
Zhihui Zhao,Qian Bai,Juanjuan Qi,Hao Han,Junhai Chen,Suiyi Song,Xudong Yang,Qiangwei Li,Jianhui Wang,Lidong Wang
Overcoming the symmetric electronic structure of single-atom catalysts (SACs) to promote the cleavage of O-O bond remains critical for efficient H 2 O 2 activation. Herein, the high-loading Fe SACs (FeN 1 C 2 /C 2 N, 7.2 wt%) is designed via in-situ carbon defect engineering, which breaks the symmetric electronic structure through the nonplanar asymmetric coordination of Fe. DFT calculations and characterizations reveal that compared to the planar symmetric Fe-N 2 structure, N 1 -Fe-C 2 coordination modifies d-p orbital hybridization, inducing the spin state of Fe from low-spin (LS, t 2g : ↑↓ , ↑↓ , ↑↓ ; e g : _, _, _) to high-spin (HS, t 2g : ↑↓ , ↑ , ↑ ; e g : ↑ , ↑ ; _). The HS state weakens the coupling between *H 2 O 2 and Fe 3 d orbitals, promoting H 2 O 2 decomposition into abundant •OH, further achieving electron-rich pollutant Sulfamerazine (SMR) degradation with the rate constant of k obs =0.3308 min -1 . Additionally, such nonplanar asymmetric coordination releases the N atoms adjacent to the Fe sites, allowing them to form electron-transfer channel with SMR, which establishes nonradical electron transfer pathway (ETP). Pollutant pre-adsorption enables •OH to attack the target in situ along an ultrashort pathway, resulting in an efficient ETP-assisted radical oxidation mechanism. Overall, this work provides new insights into SACs design and a novel perspective for Fenton-like systems application.
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高影响因子
MICROCHEMICAL JOURNAL
·
2024
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IF 4.9
Qi Wang,Xiaoxia Bai,Fei Liu,Peipei Li,Qianlin Tang
Early diagnosis of cancer is crucial to effective treatment of the patients and to higher survival rates. Tumor marker detection as an effective and noninvasive cancer diagnosis method has important clinical significance. N 1 , N 12 -diacetylspermine (DAS) is a new tumor marker. The development of its detection methods is an urgent need for medical diagnosis and human health monitoring. The conventional detection methods of DAS are labor-intensive and time-consuming approaches. In this work, a novel electrochemical detection platform was established by integrating an organic electrochemical transistor (OECT) with a microfluidic chip and applied for trace measurement of DAS. The sensing unit is a gate electrode in the OECT modified with molecularly imprinted polymers (MIPs), which can be used as an artificial receptor to realize label-free detection. The high specific recognition ability of MIPs films combined with the amplified function of an OECT yielded a highly sensitive and selective electrochemical detection chip. The integrated microfluidic channel controlled the exact amount of solution to be delivered and provided real-time detection of DAS. The experimental results indicated that changes in channel current was proportional to DAS concentrations from 1 nM to 10 μM, with the detection limits of 0.8 nM. It is the first demonstration of the integration of a microfluidic system with a MIP-gated OECT for real-time tumor marker detection. The study results of this work helped to develop Point-Of-Care (POC) tools for the early diagnosis of lung cancer, colon cancer and breast cancer.
研究领域:
生物医学工程
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分析化学
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癌症诊断
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Yue Zang,Yibo Tu,Chuanjia Jiao,Wangnan Li,Peng Zhou,Jiahao Cheng,Gaoyuan Yang,Tianxiang Shao,Jingchuan Ye,Guodong Li,Liang Chu,Shaojian Lu,Guijie Liang,Ying Liang,Jingyang Wang,Zhicheng Zhong,Run Hu,Wensheng Yan
Although the record power conversion efficiency (PCE) of perovskite solar cells (PSCs) has been continuously boosted, the effective large-area manufacturing and good device stability are the major challenges toward their commercialization. Here, we report a green additive of N-methyl-2-piperidone (N1) to modify the perovskite precursor, enabling the one-step fabrication of high-quality large-area perovskite films with enhanced PCE and stability. The results show that due to the stronger complexation ability of N1 additive with PbI 2 , the generated PbI 2 -N1 complex can effectively control the nucleation and growth of perovskite to realize lead halide-framework template-assistant crystallization reaction with organic cation in the one-step solution preparation of (FAPbI 3 ) 0.95 (MAPbBr 3 ) 0.05 , leading to the homogeneous pinhole-free perovskite films with few defects. Therefore, the PSC device with small active-area of 0.09 cm 2 exhibits an efficiency of 23.2 %. Moreover, highly efficient slot-die printed 5 × 5 cm 2 PSC module has been obtained with a champion PCE of 21 % and improved device stability over 1000 h. This work demonstrates a new strategy to realize high-quality large-scale perovskite films for solution-processed PSC modules, which may be further improved and extended to other kinds of PSCs and applications such as perovskite light-emitting diodes and detectors.
研究领域:
材料科学
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光伏技术
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纳米材料
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能源化学
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功能材料
·
器件物理
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表面与界面工程
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DOI
高影响因子
POSTHARVEST BIOLOGY AND TECHNOLOGY
·
2025
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IF 6.8
Jiayi Song,Maomao Ma,Yijian Wu,Yan Hu,Xinyi Wu,Peipei Guan,Bin Zeng
Green mold, caused by Penicillium digitatum , is one of the most destructive postharvest diseases of citrus fruits, leading to significant rot and economic losses. In this study, the antifungal activity and underlying mechanism of the novel antimicrobial peptide (AMP) N1–6L7A against P. digitatum were investigated. Additionally, the potential application of N1–6L7A for controlling postharvest green mold in Citrus sinensis (L.) Osbeck was examined. N1–6L7A exhibited potential antifungal efficacy by inhibiting both mycelial growth and spore germination of P. digitatum . Furthermore, it demonstrated excellent thermal stability, pH tolerance, and biosafety. The results of fluorescence microscopy assay, cell component leakage, and microscopic observations revealed that N1–6L7A severely damaged the fungal membrane of P. digitatum , leading to the release of intracellular nucleic acids and proteins. N1–6L7A treatment also induced excessive intracellular reactive oxygen species (ROS) production, collapse of mitochondrial membrane potential, and decreased activities of malate dehydrogenase (MDH) and ATPase. Gel retardation assay indicated that P. digitatum -DNA was a target of N1–6L7A. Furthermore, transcriptomic analysis suggested that N1–6L7A might inhibit the growth of P. digitatum by blocking the expression of genes related to the ribosome, amino acid metabolism, and pyrimidine metabolism. Meanwhile, the peptide potentially promoted the expression of genes involved in steroid biosynthesis. Notably, in vivo assays confirmed that N1–6L7A effectively controlled P. digitatum infection in citrus fruits and enhanced host resistance by activating defense-related enzymes. Collectively, our results suggested that N1–6L7A could be used as an alternative fungicide to prevent green mold in citrus fruits.
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高影响因子
Evidence-based Complementary and Alternative Medicine
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2017
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IF 1.74
Jing Wang,TongMing Li,Linquan Zang,Xuediao Pan,Sujun Wang,Yanyan Wu,Guixiang Wang
Apigenin is a nonmutagenic flavonoid that has antitumor properties. Polyamines are ubiquitous cellular polycations, which play an important role in the proliferation and differentiation of cancer cells. Highly regulated pathways control the biosynthesis and degradation of polyamines. Ornithine decarboxylase (ODC) is the rate-limiting enzyme in the metabolism, and spermidine/spermine-N1-Acetyl transferase (SSAT) is the rate-limiting enzyme in the catabolism of polyamines. In the current study, the effect of increasing concentrations of apigenin on polyamine levels, ODC and SSAT protein expression, mRNA expression, cell proliferation and apoptosis, and the production of reactive oxygen species (ROS) was investigated in SW620 colon cancer cells. The results showed that apigenin significantly reduced cell proliferation, decreased the levels of spermidine and spermine, and increased previously downregulated putrescine contents. Apigenin also enhanced SSAT protein and mRNA levels and the production of reactive oxygen species in SW620 cells, though it had no significant effect on the levels of ODC protein or mRNA. Apigenin appears to decrease the proliferation rate of human SW620 cells by facilitating SSAT expression to induce polyamine catabolism and increasing ROS levels to induce cell apoptosis.
研究领域:
肿瘤学
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分子生物学
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药理学
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DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）