Advanced Physics Research
·
2022
·Vol. 2
·期 4
·2200056
·
IF 0
Kuangnan Lyu,Gaochao Liu,Maxim S. Molokeev,Zhiguo Xia
Near-infrared (NIR) phosphor-converted light-emitting diodes (pc-LEDs) are desired for optoelectronic and biomedical applications, while the development of target broadband NIR phosphors still remains a significant challenge. Herein, a kind of Cr 3+ -doped AlNbO 4 phosphors with a broad NIR emission ranging from 650 to 1400 nm under 450 nm excitation are reported. A giant red-shift emission peak from 866 to 1020 nm together with broadened full width at half-maximum of 320 nm is achieved simply by varying the doped Cr 3+ concentrations. Structural and spectroscopy analysis demonstrate that a concentration-dependent site-occupation of Cr 3+ emitters in different Al 3+ sites is responsible for the tunable NIR luminescence. The as-fabricated NIR pc-LED based on optimized AlNbO 4 :Cr 3+ phosphor exhibits great potential in night-vision applications. This work provides a novel design principle on the Cr 3+ -doped AlNbO 4 phosphor with tunable broadband luminescence from NIR-I to NIR-II, and these materials can be employed in NIR spectroscopy applications.
研究领域:
光学材料
·
生物医学光学
·
光电子学
·
无机功能材料
·
分子影像
✓ 已验证
DOI
ACS Applied Nano Materials
·
2025
·
IF 5.5
Qi He,Qiuping Yang,Xiangyu Tong,Xiaotong Zhang,Yi Wang,Xiaohu Wu,Yanyun Ma,Yiqun Zheng
Precise spectral modulation of plasmonic absorptions in the near-infrared (NIR-I and NIR-II) regions is crucial for matching laser wavelengths in practical applications, driving significant interest in sensing, photothermal therapy, and bioimaging. In this work, we show that silver (Ag) alloying in gold (Au) nanosheets provides tunable plasmonic absorption across both NIR-I (700–950 nm) and NIR-II (1000–1350 nm) spectral windows while preserving their intrinsic two-dimensional morphology. Through controlled variation of the Ag/Au ratio in a seed-mediated synthesis, we observe a continuous blue-shift of the in-plane dipole plasmon resonance from 1000 nm (NIR-II) to 700 nm (NIR-I). Theoretical simulations confirm that Ag incorporation tunes plasmonic responses by modulating both the free electron density and local dielectric environment. This morphology-preserved alloying approach establishes a versatile platform for developing optically switchable nanomaterials with promising applications in multiplexed biosensing and wavelength-selective photothermal therapy.
研究领域:
纳米材料
·
等离激元学
·
光学材料
·
光热治疗
·
生物传感
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICA CHIMICA ACTA
·
2025
·
IF 6
Fanfan Guo,Yuanyuan Hu,Huiwen Zhou,Yuanjin Li,Jiadi Li,Guichuan Wei,Jing Long Han,Wenyue Gao,Sisi He,Wenxin Niu,Ling Zhang
NIR-I electrochemiluminescence (ECL) is emerging as highly sensitive detection strategy due to its low background at the ambient conditions. Nonetheless, the applications of current NIR-I ECL nanoprobes are limited to the harsh synthetic/testing condition, high toxicity, low signal, and poor biocompatibility. In this study, glutathione/lipoic acid-protected trimetallic Au 6 PtAg nanoclusters (GSH/LA/Au 6 PtAg NCs) are demonstrated as an efficient nanoprobe with strong ECL signals around 850 nm in the presences of triethylamine. Critically, the alloying of Ag + into the bimetallic Au 2.5 Pt NCs altered the electronic structures of Pt(II), valences of Au(0), and the zata potentials of NCs, promoting the ECL intensities at 850 nm by 1.0 time. Additionally, the partly ligand-exchange of GSH by LA further increased the ECL intensities at 850 nm by 2.2 times through accelerating electron transfer processes. Meanwhile, the NIR-I fluorescence ( λ emit = 910 nm) was enhanced. More importantly, the utilization of GSH/LA/Au 6 PtAg NCs μg −1 is enhanced by 3000 times after embedding into SiO 2 microspheres ( D , 318 nm). Because noradrenalin has substantial inhibition effects to NIR-I ECL of GSH/LA/Au 6 PtAg/SiO 2 , 1.0 nM−0.1 mM noradrenalin was detected with the low limit of detection as 0.04 nM (S/N = 3) selectively. Biomolecules, glucose, ascorbic acid, or uric acid didn't interrupt the detection of noradrenalin. The sensitivity of this ECL method to detect noradrenalin is much higher than those in previous reports, enabling the early diagnosis of neurogenic diseases.
研究领域:
分析化学
·
纳米技术
·
生物分析
·
电化学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Xingxing Gao,Jingjing Li,Xiaoxu Li,Xing Yin,Shunze Cao,Ximing Pu,Juan Wang,Xiaoming Liao,Zhongbing Huang,Guangfu Yin
Polydopamine (PDA) possesses potential as a photothermal agent for tumor treatment owing to its photothermal capacity, chemical modifiability, excellent biocompatibility, and selective biodegradability. However, weak near-infrared (NIR) light absorption seriously hinders its actual utilization, especially in NIR-II. This study presents a novel molecularly modified PDA with remarkably increased NIR absorption and remarkably enhanced photothermal conversion capacity in both NIR-I and NIR-II. Dopamine monomers are covalently bound with elaborately selected 2,6-pyridinedicarboxylic acid (DPA) through an amidation reaction and then undergo an oxidative polymerization to form DPA-doped PDA nanoparticles (DPA-PDA NPs). By constructing donor–acceptor pairs and extending the conjugation length of molecular units, the energy band gap of DPA-PDA between the highest occupied molecular orbital and the lowest unoccupied molecular orbital is diminished from 0.77 to 0.45 eV, facilitating the electron low-energy transition. Meanwhile, the content of carbon-centered free radicals is obviously raised via suppressing their dimerization and quenching by the conjugation effect and steric hindrance effect, where the strengthened electron spin and vibration may promote charge and energy transfers, increasing and accelerating the excited electron nonradiative decay. As a result, the DPA-PDA NPs exhibit the enhanced NIR light absorption (196 and 205% over PDA) and much higher photothermal conversion efficiency (1.4 and 2.1 times that of PDA) under 808 and 1064 nm irradiation, respectively, achieving more effective tumor cells inhibition in vitro and tumor ablation in vivo. Interestingly, photothermal therapies with DPA-PDA for tumor-bearing mice emerge with higher tumor elimination (nearly 100%) under 1064 nm irradiation than that under 808 nm irradiation (94.3%), without recurrence within 20 days, which is attributed to both the enhanced photothermal capacity of DPA-PDA and the stronger tissue penetration ability of NIR-II. This design provides a new option to enhance the photothermal capacity of polydopamine as an applicative photothermal agent for tumor therapy.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Electronic Materials
·
2025
·
IF 4.7
Ting Zhang,Xiaoqian Zhang,Qinan Mao,Fangyi Zhao,Heyi Yang,Xinyue Li,Jiasong Zhong
Lanthanide doping has been instrumental in tuning the emissions of double perovskite halides (DPHs) into the near-infrared (NIR) region. However, the limited penetration depth of UV excitation and typically low photoluminescence quantum yield (PLQY) of these materials restrict their utility in biomedical applications. In this paper, Cr3+-doped lead-free DPHs (Cs2NaScCl6:Cr3+) have been explored, featuring a broadband NIR emission spanning 800–1300 nm and an impressive PLQY of 76.9%. Oriented toward biological applications, we employ Yb3+ as a codopant to be introduced into Cs2NaScCl6:Cr3+. The novel Cs2NaScCl6:Cr3+,Yb3+ crystal powder displays a red-shifted emission (peaking at 995 nm) with a remarkably narrower full width at half-maximum (fwhm) of 51 nm. Importantly, the efficient energy transfer between Cr3+ and Yb3+ enables Cs2NaScCl6:Cr3+,Yb3+ to maintain a PLQY of 46.1% upon 780 nm excitation. Leveraging its NIR-I excitable and NIR-II emissive properties, Cs2NaScCl6:Cr3+,Yb3+ presents great potential in biodetection and bioimaging applications. Its superior energy transfer efficiency, high PLQY, and favorable spectral characteristics position this material as a promising candidate for advanced biomedical techniques requiring deep tissue penetration and high imaging contrast.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
Materials Today Chemistry
·
2024
·
IF 6.7
Yuan Tang,Pengbo Lyu,Desheng Yin,Zhaoqi Liu,Nian Pan,Kai Li,Ying Ye,Changfu Xu,Lizhong Sun
Ultra-broadband near-infrared (NIR) lighting sources covering NIR Ⅰ to III regions are pivotal components for NIR spectroscopy devices. However, achieving ultra-broadband and efficient emission covering the entire NIR Ⅰ to III regions remains a significant challenge. To address this, we selected Mg 7 Ga 2 GeO 12 as host material to realize ultra-broadband NIR emission. Density functional theory calculations on formation energies confirmed the feasibility of doping both Ni 2+ and Cr 3+ within Mg 7 Ga 2 GeO 12 . Band structure calculations reveal a significantly reduced band gap upon the doping of Ni 2+ . Following that, we synthesized Mg 7 Ga 2 GeO 12 :Ni 2+ through conventional solid-state-reaction method. This phosphor exhibits broadband NIR emission with a full-width-at-half-maximum of 377 nm in the range of NIR II ∼ III (1100–2100 nm). To further enhance the emission efficiency, we co-doped Mg 7 Ga 2 GeO 12 :Ni 2+ phosphor with Cr 3+ . This co-doping strategy not only dramatically enhances the Ni 2+ emission intensity, but also extends the lower limit of emission band to 600 nm. However, a spectral gap around 1150 nm remains between Cr 3+ and Ni 2+ emission centers. To bridge this spectral gap, we employed LiScSiO 4 :Cr 3+ phosphor alongside Mg 7 Ga 2 GeO 12 :Ni 2+ ,Cr 3+ phosphor to fabricate a phosphor converted LED (pc-LED) with ultra-broadband NIR emission covering entire NIR Ⅰ to III regions. By utilizing this pc-LED as the lighting source for NIR spectral detection, multiple organic functional group signals can be identified simultaneously in NIR II and III bands from 1000 to 2100 nm. The performance of such an NIR pc-LED not only confirms the application potential of Mg 7 Ga 2 GeO 12 :Ni 2+ ,Cr 3+ phosphor in non-destructive spectral analysis but also underscores the feasibility of combining two phosphors to achieve ultra-broadband NIR pc-LEDs, rendering them suitable to be lighting sources for portable spectrometers.
研究领域:
材料科学
·
光学
·
光谱学
·
光子学
·
化学
✓ 已验证
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2018
·
IF 8.097
Jiulong Zhao,Chunhua Zhou,Chenyao Wu,Huan Wu,Chunping Zhu,Changqing Ye,Shige Wang,Duowu Zou
Alginate-Ca2+ hydrogel has been used to immobilize photothermal materials as well as chemotherapy drugs at lesion sites to prevent their entry into the bloodstream. However, the alginate-Ca2+ gelation mechanism may result in hardening of the blood vessels because of Ca2+ migration to the lesion site. In this study, a unique and facile one-pot formation of chemotherapeutic (doxorubicin, DOX) and polypyrrole-containing alginate hydrogel was designed by introducing Fe3+, which can synchronously induce the polymerization of pyrrole and gelatinization of alginate, into the DOX/pyrrole/alginate solution. The formed composite hydrogel was endowed with superior photothermal conversion properties in both the NIR-I (650–950 nm) and NIR-II (1000–1700 nm) biowindows and light-to-heat conversion efficiency higher than 50%, which enabled effective tumor hyperthermia treatment. Besides, near-infrared (NIR) irradiation could be used as a remote controller to trigger the DOX-release because of the heat generation, thus achieving continuous and on-demand tumor chemotherapy. The composite polymer hydrogels exhibited favorable hemo-, cyto-, and histocompatibility, as well as simple and cost-effective preparation and good clinical prospects.
研究领域:
生物医学工程
·
肿瘤学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Inorganic Chemistry Frontiers
·
2026
·
IF 6.2
Jia-Wei Liu,Dan Li,Peng-Xu Lu,Tao-Xiao Wen,Yan-Ru Chen,Jian-Hua Jia,Ming-Liang Tong
Luminescent metal nanoclusters featuring near-infrared (NIR) emission hold promise for diverse applications. Although ligand engineering can modulate their NIR optical properties, separating the effects of single-ligand in dual-ligand systems remains challenging. In this study, we employed a controlled variable approach to prepare three structurally comparable silver-rich clusters-Ag11Cu3, Cu@Ag14-xCux, and Ag18. By maintaining a constant thiolate ligand and solely varying the phosphines, we elucidated the synergistic regulatory impacts of the ligands on the core configuration and excited-state dynamics. Structural and optical analyses reveal that the monodentate phosphine (TPP) stabilizes an Ag6@Ag5Cu3 core of the cluster Ag11Cu3, leading to NIR-I emission (720 nm) originating from mixed triplet state metal-centered and charge transfer transitions. In contrast, the bidentate phosphine (trans-dppe) facilitates the formation of a nested Ag6@Ag8@Ag4 core of the cluster Ag18, triggering NIR-II emission (1424 nm) associated with highly delocalized core-based excited states. Moreover, the spatial influence of the chiral bidentate phosphine ((S,S)-BDPP) can induce core-structural distortion, which promotes nonradiative decay and results in luminescence quenching of the cluster Cu@Ag14-xCux. This work clarifies the relation between the structure and luminescence properties of ligand-mediated metal clusters, offering valuable insights for the design of tailored NIR optical materials.
✓ 已验证
DOI
高影响因子
Laser & Photonics Reviews
·
2023
·Vol. 18
·期 1
·2300784
·
IF 11
Taoze Wang,Yuzhen Wang,Weibin Chen,Zhiguo Xia
Near-infrared (NIR) phosphor-converted light-emitting diodes (pc-LEDs) lighting sources are applied in non-destructive examination and illumination supplements for night monitoring. As a critical component of NIR pc-LED, NIR phosphors are required to possess a high external quantum efficiency (EQE), super thermal stability, and broadband emission to meet applications. Here, Na 2 SrGe 6 O 14 :Cr 3+ (NSGO:Cr) glass ceramics (GC) bulk via highly crystallization from glass precursor is fabricated and demonstrates an ultrabroad emission band centered at 815 nm with a full width at half-maximum (FWHM) of 214 nm and a high EQE of 49.2%. Moreover, Yb 3+ co-doping significantly enhances Cr 3+ → Yb 3+ energy transfer (ET) due to the stronger Yb 3+ : 2 F 7/2 - 2 F 5/2 absorption. Benefiting from the ET process, the Cr/Yb co-doped GC exhibits NIR-I/II emission with improved thermal stability from 30.1% to 65.0%. Furthermore, an encapsulant-free NIR GC-converted LED (GCc-LED) is prepared and exhibits 52.2 mW NIR output power with a high photoelectric conversion efficiency (PCE) of 19.4%. Under a large current of 600 mA, the NIR device exhibits a watt-level output power of 922.4 mW with a PCE of 9.1%. Compared to conventional NIR powder phosphors, NSGO:Cr/Yb GC with high performance can open up an avenue for the fabrication of high power NIR lighting sources.
研究领域:
材料科学
·
光学工程
✓ 已验证
产品关联
DOI
高影响因子
Advanced Healthcare Materials
·
2025
·
IF 9.6
Minggang Yang,Yufan Zhang,Zhenhao Hou,Jianbo Wu,Fuwei Liu,Jun Wu,Kelvin W.K. Yeung,Wenhao Qian,Xuanyong Liu,Liang Kong,Yunpeng Li,Jiajun Qiu,Guocheng Wang
Antibiotic therapy is a key strategy for treating infections associated with orthopedic implants, yet its limited effectiveness and potential to disrupt bone healing highlight the need for innovative approaches. Herein, a TiO 2 -Graphene (TiO 2 -G) metastructure is developed on Ti implant surface using a hydrothermal method coupled with plasma-enhanced chemical vapor deposition (PECVD), showing strong near-infrared light (NIR) absorption. The antibiotic doxycycline (DOX) is successfully loaded onto TiO 2 -G and exhibited enhanced NIR release. The promising antibacterial efficacy is proven by both in vitro and in vivo tests with NIR irradiation for 5 min, which is ascribed to the synergistic photocatalytic activity of TiO 2 -G and NIR-responsive release of DOX. Interestingly, after 5 min of NIR irradiation, the TiO 2 -G metasurface neutralized the immediate negative effects of photodynamics and even upregulated the expression of osteogenic genes (osteocalcin (OPN), osteopontin (BSP), and bone sialoprotein (OCN)), with particularly enhanced effects observed on day 14. Moreover, the sustained release function of TiO 2 -G significantly mitigated the cytotoxicity of free antibiotics with antibacterial capabilities comparable to those of TiO 2 -G/DOX under NIR irradiation for 5 min. Consequently, the in vivo studies proved that the TiO 2 -G metastructure enhanced the osteointegration of the implant even in the absence of infection when loaded with DOX.
研究领域:
生物医学工程
·
材料科学
·
微生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMISTRY-A EUROPEAN JOURNAL
·
2024
·
IF 3.9
Dandan Li,Wenrong Zhao,Gang Li,Yan Xu,Liang Xu,Bo Tang
Graphical Two novel star-shaped fluorophores named PDI−S and PDI−Se are constructed by S/Se-fused perylene diimides (PDIs) connected with bicarbazole core. Particularly, PDI−S presents excellent two-photon absorption cross-action (δ TPA ) of 3775 GM excited with 800 nm light, which is the highest value based on PDIs motif in the NIR−I region (700–900 nm). Two-photon absorption (TPA) has attracted growing attention over recent years owing to the wide range of applications in organic nonlinear optical (NLO) materials. The quantitative sensitivity of a two-photon molecular entity is determined by its TPA cross-section (δ TPA ). Perylene diimides (PDIs) are excellent n-type organic semiconductor materials demonstrating distinguished thermal, optical, and chemical stability. Nonetheless, PDIs-based scaffolds exhibit poor δ TPA in the NIR−I region (700–900 nm) due to the lack of suitable molecular design. Here, two novel star-shaped PDIs fluorophores, namely PDI−S and PDI−Se, were constructed by four periphery S/Se-fused PDIs connected with bicarbazole core. PDI−S manifested excellent δ TPA of 3775 GM, which are among the highest values reported for PDIs excited in the NIR−I region.
研究领域:
有机化学
·
材料科学
✓ 已验证
DOI
PubMed
高影响因子
Advanced Optical Materials
·
2026
·Vol. 14
·期 17
·e71226
·
IF 7.2
Jinwei Liu,Jiaxin Li,Guojun Zheng,Chuan Liao,Jianhong Wu,Jianrong Qiu,Wenge Xiao
Cr 3+ emission can well cover the NIR-I region (700–950 nm), while Ni 2+ emission typically extends across the NIR-II region (1000–1700 nm), making the Cr 3+ –Ni 2+ co-doped phosphors among the most promising ultrabroadband NIR emitters for phosphor-converted light-emitting diodes (pc-LEDs). However, a pronounced gap or even spectral discontinuity between the two emission bands results in a severely imbalanced photon flux across the spectrum, thereby degrading multicomponent spectral detection accuracy and significantly limiting the practical applications of such NIR pc-LED devices. Here, we report a superstoichiometric spinel MgO· n Ga 2 O 3 :Cr 3+ ,Ni 2+ ( n > 1) phosphor, in which the excess Ga 2 O 3 increases the degree of cation inversion to achieve a long-wavelength Cr 3+ emission at 895 nm, substantially elevating the spectral gap height to a state-of-the-art value of ≈36%. Moreover, efficient energy transfer from Cr 3+ to Ni 2+ enables the optimized MgO·1.2Ga 2 O 3 :Cr 3+ ,Ni 2+ phosphor to demonstrate a high internal quantum efficiency of 97% and excellent thermal stability. Finally, the as-fabricated NIR pc-LED delivers an exceptional photoelectric efficiency of 21% at 20 mA and a maximum NIR output power of 62 mW at 350 mA. This work establishes a new pathway toward next-generation compact ultrabroadband NIR pc-LEDs featuring unprecedented spectral flatness and superior optoelectronic performance.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）