FOOD CHEMISTRY
·
2025
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IF 9.8
Teng Zhang,Yunrui Xing,Jiale Yao,Zhuan Yang,Jucai Wang,Linlin Chen,Lunguang Yao
P,p′-DDA, similar to DDT, accumulates in the food chain and poses potential risks to human health. Herein, a novel sensitive and specific mAb-10B4D7 was screened and subsequently rAb-10B4D7 was expressed by genetic engineering. Utilizing rAb-10B4D7, an immunochromatographic test strip (ITS) was developed with visual limit of detection 12.5 μg/L within 15 min, displaying no cross-reactivity with o,p′-DDT, p,p′-DDT, p,p′-DDD, and p,p′-DDE. Further, a linear relationship between log(concentration of p,p′-DDA) and the optical density ratio of test (T) line and control (C) line was established with limits of detection of 1.03 μg/kg, recoveries of 79.3–106.8 %, and coefficients of variation below 10 %. Molecular docking simulations identified two critical residues (Arg-H62, Phe-L98) forming three hydrogen bonds with p,p′-DDA, resulting in the high specificity and affinity of rAb-10B4D7, with a K D of 5.81 × 10 −9 mol/L. These results indicated that the ITS was suitable for monitoring p,p′-DDA and organochlorine residues in seawater and shellfish.
研究领域:
环境监测
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免疫技术
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分析化学
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海洋生物学
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食品安全
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分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MOLECULES
·
2021
·Vol. 26
·期 22
·6849
·
IF 4.412
Yan Fan,Tao Wang,Yinwei Qiu,Yinli Yang,Qiubo Pan,Jun Zheng,Songwei Zeng,Wei Liu,Gang Lou,Liang Chen
Graphene p-n junctions have important applications in the fields of optical interconnection and low–power integrated circuits. Most current research is based on the lateral p-n junction prepared by chemical doping and other methods. Here, we report a new type of pure graphene oxide (pGO) vertical p-n junctions which do not dope any other elements but only controls the oxygen content of GO. The I–V curve of the pGO vertical p–n junction demonstrates a remarkable rectification effect. In addition, the pGO vertical p–n junction shows stability of its rectification characteristic over long-term storage for six months when sealed and stored in a PE bag. Moreover, the pGO vertical p–n junctions have obvious photoelectric response and various rectification effects with different thicknesses and an oxygen content of GO, humidity, and temperature. Hall effect test results show that rGO is an n–type semiconductor; theoretical calculations and research show that GO is generally a p–type semiconductor with a bandgap, thereby forming a p–n junction. Our work provides a method for preparing undoped GO vertical p–n junctions with advantages such as simplicity, convenience, and large–scale industrial preparation. Our work demonstrates great potential for application in electronics and highly sensitive sensors.Keywords:undoped p–n junction;vertical p–n junction;graphene oxide
研究领域:
材料科学
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电子工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2021
·
IF 19.503
Shan Ni,Hongnan Qu,Zihao Xu,Xiangyang Zhu,Huifang Xing,Li Wang,Jiemiao Yu,Huizhou Liu,Congmei Chen,Liangrong Yang
Heterogeneous electrocatalysis usually involves the charge transfer between the surface of electrocatalysts and corresponding reactants. Thus, modulating the surface electron density of electrocatalysts is an effective strategy to boost the electrocatalytic activity of targeted reactions. Herein, the NiSe 2 /FeSe 2 p-p heterojunction is constructed via a simple selenization method for both oxygen evolution reaction (OER) and urea oxidation reaction (UOR). The designed NiSe 2 /FeSe 2 electrocatalyst exhibits a superior activity towards OER, which only requires a low overpotential of 256 mV to reach a current density of 10 mA cm −2 , and surpasses other selenides and even the state-of-the-art RuO 2 . Impressively, when employed as the UOR electrode, the NiSe 2 /FeSe 2 heterojunction needs only 127 mV overpotential at 50 mA cm -2 , remarkably superior to other selenides and confirming the less energy consumption for UOR. The comprehensive analysis demonstrates that the well-designed built-in electric field at the heterointerface of NiSe 2 /FeSe 2 p-p heterojunction due to the difference of energy levels can expedite the charge transfer and thus strengthen the conductivity of heterojunction electrocatalyst. Moreover, the self-driven electron transfer across the NiSe 2 /FeSe 2 heterointerface can induce local charge redistribution at the interface region, which is beneficial for the adsorption of OH − and urea owing to the electrostatic interaction. Therefore, the designed NiSe 2 /FeSe 2 p-p heterojunction with regulated electronic structure displays extraordinary electrocatalytic activity for both the OER and UOR. This study demonstrates a novel strategy to manipulate the surface/interface charge states of electrocatalysts for improving the catalytic activity of OER and UOR, and provides new guidelines for exploring other superior electrocatalysts.
研究领域:
材料科学
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电化学
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催化科学
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2024
·
IF 8.1
Xu Kong,Kai Wang,Zhiliang Jin
More efficient hydrogen production can be achieved by rationally designing heterojunction photocatalysts and constructing interactions between photocatalysts. Herein, The CoP/Cu 3 P (Co–Cu–P) nanocubes were designed using Prussian blue analogue (PBA) as a template through the calcination phosphating method. The novel crystalline-amorphous Co–Cu–P/GDY p-n heterostructures photocatalyst was prepared by a stir-assisted low-temperature water bath method. Under visible light irradiation, the hydrogen evolution efficiency of the Co–Cu–P/GDY-3 heterostructures reached 4790.0 μmol g −1 h −1 , surpassing that of GDY (523.9 μmol g −1 h −1 ) and Co–Cu–P (2458.5 μmol g −1 h −1 ). The remarkable hydrogen evolution activity of the composite catalyst can be attributed to the presence of p-n heterojunction, while the crystalline-amorphous structure promotes efficient interfacial charge transfer. Additionally, the rough and porous nature of the Co–Cu–P/GDY heterostructures surface facilitates mass transfer and hydrogen diffusion during photocatalysis. The charge transfer pathway of the p-n heterojunction was confirmed through various characterizations, including photoluminescence spectroscopy (PL), ultraviolet photoelectron spectroscopy (UPS), valence band X-ray photoelectron spectroscopy (VB-XPS), density functional theory (DFT) calculations, and other relevant techniques. This study offers a fresh perspective on designing PBA derivatives with graphdiyne (GDY) to construct heterostructure photocatalysts for enhanced photocatalytic performance.
研究领域:
材料科学
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光催化
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能源化学
✓ 已验证
产品关联
DOI
高影响因子
ENVIRONMENT INTERNATIONAL
·
2019
·
IF 7.943
Jing Zhan,Yiran Liang,Donghui Liu,Xiaoran Ma,Peize Li,Wangjing Zhai,Zhiqiang Zhou,Peng Wang
Background The prevalence of obesity has raised global concerns. Environmental pollutants are one of the main causes of obesity. Many studies have demonstrated that dietary fiber could reduce obesity induced by high-fat diets, but whether environmental pollutant-induced obesity can be reversed is still unknown. Objectives This study aimed to investigate the effects of pectin on obesity induced by a typical environmental pollutant p,p'-dichlorodiphenyldichloroethylene (p,p′-DDE) and explore the underlying mechanism by which pectin reversed p,p′-DDE-induced obesity. Methods p,p′-DDE was used to induce obesity in C57BL/6J mice and pectin was supplied during and after cessation of p,p'-DDE exposure. Body and fat weight gain, plasma lipid profile and insulin resistance of mice were assessed. Gut microbiota composition and the levels of short-chain fatty acids (SCFAs) as well as the receptor proteins and hormones in the SCFAs-related signaling pathway were analyzed. Moreover, p,p′-DDE levels in various tissues of mice were detected. Results Pectin supplementation reversed body and fat weight gain, dyslipidemia, hyperglycemia and insulin resistance in p,p′-DDE-exposed mice. Furthermore, pectin apparently altered the p,p′-DDE-induced microbial composition and then promoted the levels of SCFAs in colonic feces as well as the expression of G-protein coupled receptors and the concentration of hormone peptide YY (PYY) and glucagon like peptide-1 (GLP-1). Pectin treatment also significantly reduced p,p′-DDE accumulation in mice tissues during p,p′-DDE exposure but did not change p,p′-DDE metabolism after termination of p,p′-DDE exposure. Conclusions Pectin had a good effect on reducing p,p′-DDE-induced obesity through regulating gut microbiota and provided a potential strategy for the treatment of environmental pollutant-caused health problems.
研究领域:
营养学
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毒理学
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微生物学
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代谢学
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内分泌学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2021
·
IF 4.098
Guangda Xu,Ye Sun,Yao Zhang,Lixin Xia
The conversion of p -aminothiophenol (PATP) or p -nitrothiophenol (PNTP) to p,p ′-dimercaptoazobenzene (DMAB) has been used as model reactions to study plasmon-catalyzed reaction on nanoparticles. Herein, we report the conversion of PNTP to DMAB which is triggered by SO 3 2− ions on gold nanoparticles (AuNPs) for the first time. With the addition of SO 3 2− , the Raman peaks at 1139, 1392, 1437 cm −1 appears, which indicates the formation of DMAB. The experiment results suggested that the synergistic effect of AuNPs and SO 3 2− promoted the conversion of PNTP to DMAB. Besides, the proposed catalysis system is high selectivity to SO 3 2− ions, which provides a new detection route to SO 3 2− ions in the future. More importantly, the possible reaction mechanism has been put forward which is helpful to understand the surface plasmon-assisted catalytic reduction of PNTP on the surface of SERS substrate.
研究领域:
化学
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纳米科学
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催化反应
✓ 已验证
DOI
高影响因子
Frontiers in Physiology
·
2020
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IF 3.367
Song Manyu,Wang Chaoran,Yang Haotian,Chen Yongping,Feng Xiujing,Li Bei,Fan Honggang
Chronic stress leads to immunosuppression and induces splenocyte apoptosis. STAT3 is a transcription factor that regulates immunity and apoptosis; however, it is unclear whether the increased expression of phosphorylated STAT3 (p-STAT3) observed in chronic stress is related to splenocyte apoptosis. To explore the relationship between splenocyte apoptosis and STAT3 in chronic stress, we treated rats undergoing a 21-day chronic restraint stress program with the STAT3 inhibitor S3I-201. This chronic stress model was verified by observing rats’ behavior and measuring their serum corticosterone levels. Chronic stress led to increased expression of anti-inflammatory cytokines, and p-STAT3 inhibition enhanced splenocyte apoptosis in chronic stress. We detected key proteins in three apoptotic pathways to determine which pathway mediated increasing splenocyte apoptosis and found that the death receptor pathway was the main apoptotic pathway that occurred in the spleen during chronic stress. The unfolded protein response (UPR) was also activated, but the Bcl-2 family was not involved in chronic stress. P-STAT3 inhibition had no influence on the Bcl-2 family and the death receptor pathway; however, p-STAT3 inhibition disrupted the pro-survival function of the UPR by decreasing the expression of ATF6α and p-IRE1α. Furthermore, p-STAT3 inhibition activated endoplasmic reticulum stress by promoting the expression of CHOP, p-JNK, and procaspase-12. Collectively, these findings indicate that the increased p-STAT3 expression during chronic stress may promote splenocyte survival by activating the UPR. Consequently, STAT3 and the UPR may be considered as potential therapeutic targets for chronic stress in the future.
研究领域:
免疫学
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压力生物学
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细胞生物学
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分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nature Catalysis
·
2023
·Vol. 6
·期 2
·174-184
·
IF 37.8
Hua Wuxing,Shang Tongxin,Li Huan,Sun Yafei,Guo Yong,Xia Jingyi,Geng Chuannan,Hu Zhonghao,Peng Linkai,Han Zhiyuan,Zhang Chen,Lv Wei,Wan Ying
Understanding sulfur conversion chemistry is key to the development of sulfur-based high-energy-density batteries. However, unclear relationships between the electronic structure of the catalyst and its activity are the major problem. Here, we provide a direct correlation between the p electron gain of S in p -block metal sulfides and the apparent activation energies ( E a ) for the sulfur reduction reaction (SRR), in particular, Li 2 S n to Li 2 S conversion, which is the rate-determining step of the SRR. The maximum p charge occurs in bismuth sulfide and results in the lowest E a and a high SRR rate in the cathode. Li–S batteries with the Bi 2 S 3 catalyst work steadily at a high rate of 5.0C with a high-capacity retention of ~85% after 500 cycles. A high areal capacity of ~21.9 mAh cm −2 was obtained under a high sulfur loading of 17.6 mg cm −2 but a low electrolyte/sulfur ratio of 7.5 μl mg −1 .
研究领域:
材料科学
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电化学
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电池技术
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催化
✓ 已验证
DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2025
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IF 19
Boxiang Gao,Yan Yan,Shuai Zhang,Zenghui Wu,You Meng,Yuxuan Zhang,Weijun Wang,Yi Shen,Siliang Hu,Bowen Li,He Shao,Pengshan Xie,SenPo Yip,Johnny C. Ho
Van der Waals (vdWs) p–n junctions assembled from 2D materials offer enhanced flexibility for creating versatile electronic and optoelectronic devices, attracting significant interest. However, the lack of reliable methods to produce high-quality p-type 2D semiconductors, especially patterned p-type channels, remains a major challenge for progress in the field. Here, a precise substitutional doping strategy for 2D semiconductors is presented, enabling the production of millimeter-scale WS 2 single-crystal thin films with tailored p-type and n-type properties. This advancement supports the fabrication of high-performance WS 2 -based p-type and n-type field-effect transistor (FET) miniaturized arrays with near-ohmic contact. Building on this progress, a WS 2 van der Waals homojunction p-n array demonstrating distinct anti-ambipolar behavior and excellent rectification characteristics is developed. In self-powered photodetection mode, leveraging the strong coupling of the vdWs homojunction interface, the device achieves an exceptional photovoltaic effect with a high specific detectivity of 3.4 × 10 10 Jones and a fast response time of 400 µs. The development of WS 2 p-n homojunction arrays presents immense potential for advancing next-generation logic electronics and optoelectronic devices, opening new avenues for large-scale industrial applications.
研究领域:
材料科学
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电子工程
·
光学
✓ 已验证
产品关联
DOI
高影响因子
Arabian Journal of Chemistry
·
2017
·
IF 4.553
Peiling Shi,Rui Xue,Yuli Wei,Xi Lei,Jiebing Ai,Ting Wang,Zheru Shi,Xiao Wang,Qin Wang,Fathelrahman Mohammed Soliman,Hao Guo,Wu Yang
A novel electrochemical platform was designed and prepared for simultaneous determination of p-acetaminophen (AMP) and p-aminophenol (AP) by combining the excellent conductivity and electrocatalytic activities of tetraaminophenyl porphyrin functionalized multi-walled carbon nanotubes (CNTs-CONH-TAPP) and gold nanoparticles (AuNPs). The as-synthesized CNTs-CONH-TAPP composites were characterized by Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy and scanning electron microscope. The incisive oxidation current responses of AMP and AP at the modified electrode promised a sensitive and selective simultaneous determination of AMP and AP. Under optimized conditions, the peak currents were directly proportional to the concentrations of AMP and AP over the ranges of 4.5–500 μmol L −1 and 0.08–60 μmol L −1 , respectively, and the limits of detection were 0.44 μmol L −1 for AMP and 0.025 μmol L −1 for AP(S/N = 3) respectively. The proposed modified electrode showed excellent selectivity, reproducibility and long-term stability and could be applied in simultaneous determination of p-acetaminophen and p-aminophenol in real samples.
研究领域:
分析化学
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材料科学
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电化学
✓ 已验证
产品关联
DOI
高影响因子
Chemistry-An Asian Journal
·
2022
·Vol. 17
·期 16
·e202200476
·
IF 4.839
Kaiqi Zhang,Hongyan Song,Zhe An,Jian Zhang,Yanru Zhu,Zhigang Chai,Xin Shu,Jing He
Graphical NiFe- LDHs/P-TCN heterojunction has been constructed with P-dopant defects and interface synergy. Moreover, Its mesoscale mechanism was elucidated among different constituent interfaces. The semiconductor based photocatalysis has become a hot spot of current research, and the key challenges are the construction of strong functional heterojunction photocatalysts, and insights on the working mechanism involved. In this work, we constructed a NiFe- LDHs/P-TCN heterojunction with P-dopant defects and interface synergy and elucidated its mesoscale mechanism among different constituent interfaces. The interface photoelectron transfer was detected by PAS, EPR and other methods, and the enhancing mechanism of the defect sites for interface electron transfer and photocatalytic activity was proposed. The interfacial electrons, photoelectric properties and photocatalytic activity are found to be positively correlated. The result is conducive for a better understanding on working mechanism of heterogeneous photocatalysts, which opened a broader research space for the rational design and construction of functional interfaces.
研究领域:
材料科学
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环境科学
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光催化
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2024
·
IF 8.1
Li Li,Zhongliao Wang,Kaixuan Kuang,Xiuzhen Zheng,Jiahui Wang,Jingbiao Ge,Sujuan Zhang,Shifu Chen
To optimize the performance of photocatalytic H 2 production, many effective methods have been developed, such as controlling morphology, designing synergetic reaction, and enhancing the utilization of photogenerated charge carriers (PCCs). In this work, an efficient CoMoO 4 /Zn 0.3 Cd 0.7 S (CMO/ZCS) photocatalyst with p-n heterojunction was constructed by incorporating Zn 0.3 Cd 0.7 S (ZCS) nanoparticles into CoMoO 4 (CMO) microflowers. Although CMO had limited activity in H 2 production under visible light irradiation, it could largely boosting the H 2 production efficiency of ZCS nanoparticles by oxidizing p-chlorobenzyl alcohol (Cl-PhCH 2 OH) in organic solvent. In the CMO/ZCS composites, the best rates of H 2 and Cl-PhCHO reached 34.28 and 35.87 mmol g −1 h −1 , respectively. The p-n heterojunction formed between CMO and ZCS may be the main enhanced reason of the excellent performance, as it could effectively improve the separation, transfer and utilization of PCCs. The design of the CMO/ZCS catalyst not only optimizes the migration and utilization of PCCs, but also provides crucial theoretical guidance and experimental insights for the development of highly efficient photocatalysts.
研究领域:
材料科学
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能源化学
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环境科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）