APPLIED OPTICS
·
2024
·Vol. 63
·期 10
·A70
·
IF 1.7
FengHong Chu,Dan Pei,ZhengLan Bian,YiSheng Sun,AnDuo Hu,GuiLin Zhang,Liang Xue,JiaWen Han,JiaMeng Zhang
Tungsten oxide (${{\rm WO}_3}$) has been widely used in hydrogen sensing due to its stable chemical properties and high oxygen vacancy diffusion coefficient. However, the response of pure ${{\rm WO}_3}$ to hydrogen is slow, and doping is an effective way to improve the hydrogen sensing performance of ${{\rm WO}_3}$ materials. In this paper, ${{\rm WO}_3}/{\rm Pt}/{\rm PEG}/{{\rm SiO}_2}$ porous film was prepared by the sol-gel method using tungsten powder, ${{\rm H}_2}{{\rm O}_2}$ and ${{\rm C}_2}{{\rm H}_5}{\rm OH}$ as precursors, polyethylene glycol (PEG) as the pore-forming agent, and tetraethyl orthosilicate (TEOS) as the ${{\rm SiO}_2}$ source material. The sensing properties of the ${{\rm WO}_3}$ composite for hydrogen were characterized by a transmission optical fiber hydrogen sensing system made at home. The process parameters such as water bath time, aging time, W:PEG ratio, and W:TEOS ratio were optimized to improve the sensitivity and response time of the sensing film. The experimental results indicate that the sensitivity is 15.68%, the average response time is 45 s, and the repeatability is up to 98.74% in 16 consecutive tests. The linearity index ${{\rm R}^2}$ is 0.9946 within the hydrogen concentration range of 5000 ppm to 50,000 ppm. The film responds only to ${{\rm H}_2}$ when the concentration of interfering gases (${{\rm CH}_4}$, CO, ${{\rm CO}_2}$) is 2000 ppm. The hydrogen sensing performance of the optimized film is significantly improved compared with that of the undoped film.
研究领域:
材料科学
·
传感器技术
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DOI
PubMed
高影响因子
JOURNAL OF LIPOSOME RESEARCH
·
2025
·
IF 4.3
Qinyang Hua,Qilong Wang,Xue Wang,Xia Jiang,Mingjie Gong,Jiaying Li,Tingyuan Li,Xiaowen Wang,Xia Cao,Jiangnan Yu,Elmurat Toreniyazov,Bin Zong,Ximing Xu,Feng Shi,Michael Adu-Frimpong
The clinical application of Isoquercitrin (IQ) is limited by its low water solubility and short retention time in the body, despite its diverse pharmacological effects. To address these issues, we prepared polyethylene glycol (PEG)-modified IQ liposomes (IQ-L) using the thin film dispersion method and optimized the formulation through a combination of One Factor at a Time (OFAT) method and response surface experiments. Characterization of the IQ-L that was prepared using the optimal formulation revealed a particle size of 185.48 nm, a polydispersity index of 0.252, a zeta potential of −33.88 mV, and an impressive encapsulation efficiency of 97.84%. In vitro release studies showed a significantly higher cumulative release rate for IQ-L compared to free IQ. Pharmacokinetic evaluations in rats demonstrated a 4.54-fold increase in the area under the concentration-time curve, a 1.63-fold prolongation of the half-life, and a 2.07-fold increase in peak concentration for IQ-L compared to unmodified IQ. Moreover, assessments of renal function in a mouse model indicated promising therapeutic effects. In summary, the PEG-modified liposome system greatly improved the solubility and in vivo retention time of IQ, thus making it a potential clinical agent for the treatment of chronic kidney disease (CKD).
研究领域:
药剂学
·
肾脏病学
·
生物医学工程
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产品关联
DOI
PubMed
高影响因子
MATERIALS LETTERS
·
2016
·
IF 2.437
Xinyu Peng,Yixin Zhang,Ying Chen,Sai Li,Bin He
A well-defined miktoarm star copolymer (μ-PEG-PCL-PLLA) was synthesized and the crystallization behavior of the copolymers was investigated. The structure of copolymer was confirmed by 1 H NMR, the molecular weight and molecular weight distribution were studied by GPC . XRD and POM were used to study the crystallization behavior of the miktoarm star copolymers. The XRD spectra showed that the miktoarm star copolymer showed low crystallinity for the joint of terminal, which limited the mobility of polymeric chains. The POM photographs revealed that PCL segments formed spherulites with PLLA crystalline grains as nucleus due to the good compatibility between PCL and PLLA.
研究领域:
材料科学
·
高分子化学
·
生物医学材料
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DOI
高影响因子
CHEMICAL PHYSICS LETTERS
·
2018
·
IF 1.686
Shiyu Zuo,Haiming Xu,Wei Liao,Lei Sun,Qiang Li,Jie Zan,Binyang Zhang,Dongya Li,Dongsheng Xia
In this study, g-C 3 N 4 Cu 2 O was successfully synthesized in the presence of PEG-400 surfactant via an acid treatment hydrothermal method and a high-temperature calcination method. The structures and properties of as-synthesized samples were characterized using a range of techniques, such as XPS, TEM, PL and BET. The g-C 3 N 4 Cu 2 O heterojunction exhibits the enhanced photocatalytic performance and high stability. It is revealed that the addition of PEG can promote the heterojunction effect of g-C 3 N 4 Cu 2 O, effectively improving the crystallinity and specific surface area of the photocatalyst, separation efficiency of photocarriers, and light absorption, thus enhancing the photocatalytic performance.
研究领域:
材料科学
·
环境科学
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DOI
高影响因子
Journal of Energy Storage
·
2022
·
IF 8.907
Dongguang Yan,Shilong Zhao,Chi Ge,Jianzhou Gao,Chengyu Gu,Yingqiang Fan
The complicated preparation process and difficulty of recycling were serious obstacles to the widespread use of solid-solid phase change materials (PCMs). Herein, we reported a novel thermoplastic solid-solid PCMs prepared by a facile one-step feeding method. In this study, the esterification and transesterification among the molten mixture of PBT , PEG and adipic acid were conducted to prepare thermoplastic PEG/PBT/Adipic acid copolymer-based PCMs. Adipic acid, as an auxiliary encapsulation agent, could prevent effectively PEG leakage of PEG/PBT/Adipic acid copolymer-based PCMs with high PEG and low PBT content during the phase change process . For PCM-6 containing 91 wt% PEG, 8 wt% PBT and 1 wt% adipic acid, there were no changes in the shape and chemical structure after multiple thermal cycles. The TG results presented that the initial thermal degradation temperature of PCMs-6 was above 200 °C, which was much higher than the processing and working temperature of PCMs-6. The latent heat of PCMs-6 could reach 136.8 J/g, showing great potential for energy storage, especially in the field of green buildings.
研究领域:
材料科学
·
高分子化学
·
能源材料
·
热功能材料
·
绿色建筑
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DOI
高影响因子
ASTRONOMICAL JOURNAL
·
2017
·Vol. 153
·期 3
·138
·
IF 2.609
J. L. Birkby,R. J. de Kok,M. Brogi,H. Schwarz,I. A. G. Snellen
We report the detection of water absorption features in the day side spectrum of the first-known hot Jupiter, 51 Peg b, confirming the star–planet system to be a double-lined spectroscopic binary. We use high-resolution (R\approx 100,000), 3.2\,\mu {\rm{m}} spectra taken with CRIRES/VLT to trace the radial-velocity shift of the water features in the planet's day side atmosphere during 4 hr of its 4.23 day orbit after superior conjunction. We detect the signature of molecular absorption by water at a significance of 5.6\sigma at a systemic velocity of {V}_{\mathrm{sys}}=-33\pm 2 km s−1, coincident with the 51 Peg host star, with a corresponding orbital velocity {K}_{{\rm{P}}}={133}_{-3.5}^{+4.3} km s−1. This translates directly to a planet mass of {M}_{{\rm{p}}}={0.476}_{-0.031}^{+0.032}\,{M}_{{\rm{J}}}, placing it at the transition boundary between Jovian and Neptunian worlds. We determine upper and lower limits on the orbital inclination of the system of 70^\circ \lt i\lt 82\buildrel{\circ}\over{.} 2. We also provide an updated orbital solution for 51 Peg b, using an extensive set of 639 stellar radial velocities measured between 1994 and 2013, finding no significant evidence of an eccentric orbit. We find no evidence of significant absorption or emission from other major carbon-bearing molecules of the planet, including methane and carbon dioxide. The atmosphere is non-inverted in the temperature–pressure region probed by these observations. The deepest absorption lines reach an observed relative contrast of 0.9\times {10}^{-3} with respect to the host star continuum flux at an angular separation of 3 milliarcseconds. This work is consistent with a previous tentative report of K-band molecular absorption for 51 Peg b by Brogi et al.
研究领域:
天文学
·
行星科学
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DOI
高影响因子
Arabian Journal of Chemistry
·
2023
·
IF 6
Zuoda Liu,Yuan Gao,Lianpu Wen,Xue Wang,Jianmin Feng,Changjun Zhu,Dejun Li,Mengli Zhao
Molybdenum disulfide (MoS 2 ), as a nanozyme, can effectively kill tumor cells by catalyzing H 2 O 2 to produce extremely poisonous hydroxyl radical (*OH). In this work, spherical MoS 2 -PEG nanozymes were prepared by hydrothermal synthesis under the modification of polyethylene glycol (PEG). Firstly, XRD, XPS, SEM, TEM, and BET were used to analyze the phase, morphology, oxidation state, and distribution of each element of nanozyme. Secondly, the determination and verification of *OH as the main reactive oxygen species (ROS) in the MoS 2 -PEG nanozyme catalyzed Fenton reaction based on 3,3′,5,5′-tetramethyldiphenylamine (TMB) color reaction and electron spin resonance (ESR). Interestingly, MoS 2 -PEG nanozymes exhibited cytostatic rates of 43.9 % and 47.2 % in vitro in mouse breast cancer cell (4T1) and mouse glioma cell (GL261) tumor cell models. In mouse fibroblast (L929) models, MoS 2 -PEG nanozymes showed excellent cytocompatibility and safety. Therefore, MoS 2 -PEG nanozyme may serve as an impactful drug to inhibit cancer cell growth.
研究领域:
生物医学
·
纳米医学
·
癌症治疗
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DOI
高影响因子
Journal of Materials Research and Technology-JMR&T
·
2021
·
IF 5.039
Yuzhe Chen,Wenxuan Zhao,Honglian Dai
Chitosan (CS) is a type of natural polysaccharide, widely used as a biomaterial on account of its great biocompatibility and the multitudes of functional groups on the long chitosan chain, making it easy for property augmentations. Nevertheless, the lack of workability and mechanical capacity limits the applications. Herein, electrospinning was chosen to fabricate oriented chitosan/polyethylene oxide (PEO) nanofibres decorated by integrin-targeting polypeptides (RGD, Arg-Gly-Asp), which is essential for cell adhesion. At the same time, porous PLGA-PEG membranes were taken as a shell of the composite film, which can provide mechanical support for the scaffold. Adequate topological anisotropic information from oriented nanofibres helps the scaffold simulate the natural axon structure, which can induce accelerated regeneration of neurotmesis. Moreover, β-Tricalcium Phosphate (β-TCP) nanoparticles were brought into nanofibers to neutralize the acidic environment produced by the degeneration of PLGA-PEG. Cell viability tests at the in vitro level and dorsal root ganglion (DRG, 1-day sucking SD rat) co-culture detection proved that the scaffold possesses excellent biocompatibility while guiding oriented regeneration of damaged nerves. In this study, a CS-RGD/PEO/β-TCP/PLGA-PEG porous composite scaffold with low cytotoxicity was fabricated. The scaffold can not only lead to the oriented growth of nerves but also has selectivity, which can help nutrient exchange while inhibiting the invasion of fibrous tissue.
研究领域:
生物医学工程
·
材料科学
·
神经再生
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产品关联
DOI
高影响因子
SOLAR ENERGY MATERIALS AND SOLAR CELLS
·
2022
·
IF 7.305
Yan Zhou,Xiaojian Wang,Dekun Sheng,Xiangdong Liu,Yuming Yang
Light-driven PEG/Ti 3 C 2 T x form-stable phase change films for energy storage crosslinked by Co 2+ were prepared through facile solution mixing. It is the strong interactions among PEG , Ti 3 C 2 T x and Co 2+ that endowed the system with excellent form-stability with only 5.0 wt% supporting. And the latent heat of samples was 142.1 J/g with light-thermal conversion and storage efficiency higher than 86.9%. Meanwhile, the samples possessed improved thermal stability and favorable thermal reliability. The fabricated films with comprehensive properties shows great perspective to be used in energy storage devices.
研究领域:
材料科学
·
能源工程
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产品关联
DOI
高影响因子
CARBOHYDRATE POLYMERS
·
2021
·
IF 9.381
Jiawei Lu,Yi Chen,Meng Ding,Xiaokun Fan,Jiawei Hu,Yihua Chen,Jie Li,Zhihan Li,Wenyong Liu
In order to develop better wound dressings, a novel chitosan hydrogel (Cn-Nm gel) was designed and fabricated by using aldehyde-4-arm polyethylene glycol (4r-PEG-CHO) to crosslink the chitosan dissolved in alkaline solution, amino-4-arm polyethylene glycol (4r-PEG-NH 2 ) was chosen as the additive simultaneously. The special dissolution technique and macromolecular crosslinking structure endows the Cn-Nm gels with better performance than that of gels prepared by acid dissolving method with micromolecule crosslinker. First, Cn-Nm gels own strong toughness with 500 kPa tensile strength and 1000% elongation, about 400% swelling ratio and fast water absorption rate. Second, about 300 kPa adhesive strength and strippability between the gels and skin is achieved. More importantly, Cn-Nm gels show nearly 100% antibacterial rate towards Escherichia coli and Staphylococcus aureus . Excellent biocompatibility is also proved by the mouse fibroblasts tests. All of the performance makes this developed chitosan-based gel be the potential candidate as a wound dressing.
研究领域:
材料科学
·
生物医学工程
·
药学
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产品关联
DOI
PubMed
高影响因子
MACROMOLECULAR BIOSCIENCE
·
2017
·Vol. 17
·期 8
·1700114
·
IF 3.238
Ting Wu,Longhai Wang,Shenggang Ding,Yezi You
A novel PEGylation polypeptide, poly(ethylene glycol)- b -poly( l -lysine)- b -poly( l -cysteine) (PEG-PLL-PCys) triblock copolymer is synthesized via the sequential ring-opening polymerization of amino acid N -carboxyanhydrides initiated by methoxypolyethylene glycol amine (mPEG-NH 2 , M w is 2 kDa). Subsequently, the obtained polypeptide is partially conjugated with fluorocarbon chains via disulfide exchange reaction. PLL segment can condense plasmid DNA through an electrostatic force to form a complex core, PEG segment surrounding the complex like a corona can prevent the complex from precipitation and reduce the adsorption of serum, while PCys segment with fluorocarbon can enhance the cellular uptake and the stability of the formed polyplex micelles in physiological conditions. Experiment results exhibit that the fluorinated polypeptides have low cytotoxicity and good gene transfection efficiency even in the presence of 50% fetal bovine serum.
研究领域:
高分子化学
·
药学
·
生物医学工程
✓ 已验证
DOI
PubMed
高影响因子
ACS Omega
·
2023
·
IF 4.1
Lei Wang,Zeen Yv,Licheng Ma,Qi Zheng,Tong Wang,Xiaokui Che,Xinglan Cui,Hongxia Li,Shenyv Wei,Xinyue Shi
Calcium carbonate is a common natural mineral with a wide range of applications. In this study, hollow calcite microspheres were successfully synthesized by using calcium chloride and sodium carbonate as raw materials in an SDS–PEG system. The results suggested that the appropriate concentration of SDS is necessary during the spherical crystallization of calcium carbonate. It was found that the crystals started to aggregate under the effect of SDS, and aggregation was enhanced with an increase in SDS concentration, leading to the transformation from hollow to solid microspheres. However, high temperatures will lead to the transformation from calcite to aragonite, resulting in the collapse of the formed spherical structure. Infrared spectroscopy and conductivity analysis suggested that when the concentration of SDS reached 0.3 g/L in the PEG–SDS system, SDS and PEG formed a spherical supramolecular structure. This structure could act as a template, leading to the aggregation of calcite through electrostatic attraction and finally to the formation of a hollow spherical structure.
研究领域:
材料科学
·
化学工程
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）