ACS Applied Materials & Interfaces
·
2020
·
IF 8.758
Yaozhuo Su,Yongqing Zhao,Wenge Zheng,Hongwei Yu,Yinfeng Liu,Linqiong Xu
In this work, an eco-friendly superhydrophobic stereo-complex polylactic acid (Sc-PLA) membrane was fabricated by a facile non-solvent-induced phase separation (NIPS) method, followed by peeling off its skin layer. By adjusting the thickness and roughness, membranes with various multi-scale microstructures could be obtained due to the formation of stereo-complex crystals during the process of phase separation. The Sc-PLA membranes display a hydrophobic wetting property. Interestingly, when the skin layer of the membrane with a 600 μm thickness was peeled off, the water contact angle on the surface of the membrane significantly improved from 142 to 152°, and the membrane displayed superhydrophobic wetting properties, which may be owing to the improvement of roughness for the surface by enlarging the exposure opportunity of finger holes and microstructures. In addition, the Sc-PLA membrane with superhydrophobicity shows excellent antifouling performance and large oil absorption capacity. Predictably, the Sc-PLA membranes may have potential applications in antifouling and oil-water separation.
研究领域:
材料科学
·
环境工程
✓ 已验证
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2024
·
IF 12.2
Yao Xie,Ze Ji,Somia Yassin Hussain Abdalkarim,Haicheng Huang,Khaydar E. Yunusov,Hou-Yong Yu
Although bioplastics and paper straws have been introduced as alternatives to single-use plastic straws, their potential environmental, economic, and social impacts have not been analyzed. This study addresses this gap by designing a polylactic acid layer interface adhesion on cellulose paper-based (PLA-P) composite straws by a dip molding process. This process is simple, efficient, and scalable for massive production. Optimizing key manufacturing parameters, including ice bath ultrasonic, overlapping paper strips (2 strips), winding angle (60°), soaking time (5 min), and drying temperature (50 °C), were systematically evaluated to improve straw quality and manufacturing efficiency. PLA chains were found to deposit onto the cellulose network through intermolecular interactions to form a consistent "sandwich" structure, which can improve adhesion, water resistance, and mechanical properties. Interestingly, PLA-P straws effectively decomposed in soil and compost environments, with a 35–40 % degradation rate within 4 months. Besides, PLA-P straw residues affected seed germination and plant growth, but no significant toxic effects were detected. Further, microplastics were observed in soil and plant tissues (roots, stems, and leaves), and their possible diffusion mechanisms were explored. The results of a comprehensive life cycle assessment (LCA) and cost analysis showed that the process improvements reduced the ecological footprint of PLA-P straws and showed good prospects for commercial application. The study's findings contribute to the understanding of bioplastics and paper straws in effectively reducing environmental impact and fostering sustainable development.
研究领域:
材料科学
·
环境科学
·
生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
LANGMUIR
·
2025
·
IF 3.9
Jun Zhang,Chao Hou,He Yu,Md All Amin Newton,Binjie Xin,Tingxiao Li
To address persistent challenges in wound care, including exudate management, infection prevention, and healing monitoring, this study developed a multifunctional fiber dressing using electrospinning technology. The system integrates a patterned hydrophobic polylactic acid/zinc oxide (PLA/ZnO) inner layer providing antimicrobial protection and exudate drainage; a polyacrylonitrile/polydopamine (PAN/PDA) intermediate water transport layer enabling unidirectional exudate transfer; and an outer PAN-based functional membrane incorporating sodium polyacrylate (SPA), phenol red (PSP), and tetracycline hydrochloride (TCH) for controlled drug release and visual wound status monitoring. The comprehensive evaluation revealed exceptional performance: rapid exudate removal within 3.35 s, 96 h sustained antibacterial drug release (68.6% cumulative release), pH-responsive chromatic transition (yellow-to-red at pH 5–9), and significant antimicrobial efficacy against Escherichia coli and Staphylococcus aureus (inhibition zone diameters of 10 and 18 mm, respectively). The dressing exhibited a balance of mechanical strength (6.1 MPa tensile strength) and breathability (13.4 mm/s air permeability rate). By integrating three core functions─efficient exudate management, antimicrobial regulation, and intelligent healing monitoring─this multifunctional architecture demonstrates clinical applicability in postoperative care and chronic wound therapy.
研究领域:
生物材料学
·
伤口护理
·
药剂学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2021
·
IF 8.742
Jinxue Cheng,Naijia Zhao,Yuxin Zhang,Yan Huang,Qinglin Huang,Changfa Xiao
Uniform-sized core-shell microspheres have received more and more attentions owing to the therapeutic application such as controlled release and drug targeting. In this work, we proposed a facile method to fabricate core-shell microspheres with uniform size. Polymethyl methacrylate (PMMA)@polylactic acid (PLA) core-shell microspheres with controllable core and shell size were prepared by combining membrane emulsification (ME) technology and solvent evaporation method. Specially, the near-field electrospinning (NFES) poly(tetrafluoroethylene) (PTFE) membranes and biaxially stretched PTFE membranes were utilized in the ME process. Subsequently, a series of PMMA@PLA core-shell microspheres were successfully prepared, where the core size of microspheres depended on the hydrophobic NFES PTFE membrane while the shell size depended on the hydrophilic biaxially stretched PTFE membrane. Meanwhile, the variation of droplet size and distribution with the evaporation temperature, pressure and continuous phase rotating speed were also investigated. When the solvent evaporation temperature was 40 °C, the obtained PMMA@PLA core-shell microspheres showed optimal morphology and size distribution. Moreover, the shell size increased with the increase of operating pressure and the decrease of continuous phase rotating speed. This facile strategy showed great potential for efficiently preparing uniform-sized core-shell microspheres in large scale.
研究领域:
材料科学
·
制药工程
·
生物医学工程
✓ 已验证
DOI
高影响因子
APPLIED CATALYSIS A-GENERAL
·
2022
·
IF 5.723
Boyong Ye,Ruru Zhou,Caili Wang,Zixuan Wang,Zixin Zhong,Zhaoyin Hou
Polylactic acid (PLA) is popularly used to replace some petroleum-based polymers due to its biodegradability. However, biodegradation of waste PLA requires specific bacteria, stringent conditions and long time. Catalytic recycling of waste PLA to valuable added products rather than composting is a sustainable green routine. In this work, catalytic alcoholysis of waste PLA to methyl lactate (MLA) was carried out over a SiO 2 @UiO-66 derived solid acid (SO 2– 4 /ZrO 2 /SiO 2 ). Characterizations indicated that SO 2– 4 /ZrO 2 /SiO 2 processed large surface area and homogenously dispersed acid sites, and it exhibited excellent performance for the alcoholysis of waste PLA under mild conditions. At 140 o C, the yield of MLA is 92.7% within 5 h, and SO 2– 4 /ZrO 2 /SiO 2 could be recycled at least five times without obvious loss of activity. The specific yield of MLA over SO 2– 4 /ZrO 2 /SiO 2 reached 2678 mg-MLA/g-cat/h, which was higher than that of H 3 PW 12 O 40 , Amberlyst-45, H β , HZSM-5 and α -ZrP. At the same time, SO 2– 4 /ZrO 2 /SiO 2 was also capable of the alcoholysis of waste PLA-based products. A possible pathway of PLA alcoholysis over SO 2– 4 /ZrO 2 /SiO 2 catalyst was proposed.
研究领域:
化学工程
·
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF BIOTECHNOLOGY
·
2024
·
IF 4.1
Yufeng Zhou,Xiaolong Sun,Jiahuan Hu,Yingjie Miao,Xiangyu Zi,Xi Luo,Yongqian Fu
Serving as a vital medical intermediate and an environmentally-friendly preservative, D-PLA exhibits substantial potential across various industries. In this report, the urgent need for efficient production motivated us to achieve the rational design of lactate dehydrogenase and enhance catalytic efficiency . Surprisingly, the enzymatic properties revealed that a mutant enzyme , Lr LDH T247I/D249A/F306W/A214Y ( Lr LDH-M 1 ), had a viable catalytic advantage. It demonstrated a 3.3-fold increase in specific enzyme activity and approximately a 2.08-fold improvement of K cat . Correspondingly, molecular docking analysis provided a supporting explanation for the lower K m and higher K cat /K m of the mutant enzyme. Thermostability analysis exhibited increased half-lives and the deactivation rate constants decreased at different temperatures (1.47–2.26-fold). In addition, the mutant showed excellent resistance abilities in harsh environments, particularly under acidic conditions. Then, a two-bacterium ( E. coli /pET28a- lrldh -M 1 and E. coli /pET28a- ladd ) coupled catalytic system was developed and realized a significant conversion rate (77.7%) of D-phenyllactic acid, using 10 g/L L-phenylalanine as the substrate in a two-step cascade reaction.
研究领域:
生物化学
·
酶工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2019
·Vol. 43
·期 24
·9696-9705
·
IF 3.069
Yashi Chen,Qing Li,Xinhong Chen,Xi Xu
Although the construction process of dual functional materials for dye and oil/water separation has been developed rapidly, the postprocess of the used separation materials themselves is still a problem owing to their non-degradation in the natural environment. Herein, novel porous membranes (PLA–PEI) are successfully prepared based on the utilization of a dip-coating technique. The adsorption isotherms and kinetics present a good correlation with Langmuir isotherms and the pseudo-second-order model, respectively. The maximum adsorption capacity of PLA–PEI for methyl orange (MO) can reach 455.10 mg g−1, which is approximately 78 times as much as that of PLA (5.82 mg g−1). In addition, the separation efficiencies of three actual oils (methylbenzene, hexamethylene and soybean oil) are all higher than 99.7%. Moreover, the obtained membranes can realize high-efficiency and simultaneous removal of MO (removal efficiency > 99.8%) and oil droplets (oil rejection > 99.7%) from mixed wastewater under a permeate flux of up to 8285 L m−2 h−1 solely driven by gravity. These results suggest that PLA–PEI is a promising and competitive candidate for water purification.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
FIBERS AND POLYMERS
·
2025
·
IF 2.3
Guo Xiaoyu,Feng Changjian,Huang Lilan,Wang Hongqiang,Liu Fang,Li Jiao
Polylactic acid (PLA) membranes offer advantages such as biodegradability, non-toxicity, and biocompatibility for oil–water separation. However, it remains challenging to fabricate PLA membranes with sufficient mechanical strength and hydrophobicity for practical applications. In this study, a superhydrophobic fibrous membrane based on PLA and Polybutylene terephthalate adipate (PBAT) is prepared via electrospinning, followed by a high-humidity treatment. The effects of PBAT content and high humidity treatment on the morphology, hydrophobicity, and mechanical properties of PBAT/PLA composite fiber membranes are investigated. The results show that the introduction of PBAT effectively enhances the fiber diameter, crystallization, hydrophobicity, and mechanical properties of PBAT/PLA fibers. Moreover, the high humidity treatment further improves the mechanical and hydrophobic properties of the membranes. When 0.2 g of PBAT is added and the high humidity treatment lasts for 24 h, the resulting PBAT/PLA fibrous membrane exhibits an outstanding water contact angle (WCA) of 158.23°, tensile strength of 3.802 MPa, excellent oil–water separation flux (6500 L/(m 2 ·h)), and efficiency of 99.80%, demonstrating great potential for oil–water separation applications.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
IONICS
·
2019
·Vol. 25
·期 7
·3189-3196
·
IF 2.289
Wang Ping,Zhou Yiyang,Xu Pei,Ding Yunsheng
Dielectric relaxation spectroscopy (DRS) was used to investigate the effect of morphological evolution on conductivity behavior of PLA/PCL blends containing P[MPEGMA-IL]. The morphology of blends changes from sea-island morphology into co-continuous morphology with increasing P[MPEGMA-IL] content. P[MEPGMA-IL] could mainly localize in PCL domains and expand to the interface layer between the PLA and PCL phase because of the low viscosity of PCL phase and the high affinity of MEPGMA groups for both polymer phases. The dielectric results were discussed in terms of α relaxation that corresponds to normal and segmental mode movement, interfacial polarization that corresponds to interfacial aggregation of charge carriers, and ac conductivity that originates from conductive network of mobile charge carriers. Co-continuous morphology and high ions concentration lead to the enhancement of segment movement and ion conductive channel in PCL phase, which correspond to high conductivity and low activation energy of PLA/PCL/8P[MEGMA-IL] blend.
研究领域:
材料科学
·
高分子化学
✓ 已验证
产品关联
DOI
高影响因子
Environment & Health
·
2025
·
IF 6.3
Xuri Wu,Han Zhang,Jingwen Chen,Feng Tan,Rui Cai,Yan Wang
The release of micro/nanoplastics (MNPs) from biodegradable plastics in gastrointestinal environments due to photoaging, along with their associated mechanisms and potential cytotoxicity, is largely unknown. Here, we show that poly(lactic acid)/poly(butylene adipate-co-terephthalate) (PLA/PBAT) films undergo ultraviolet photoaging, resulting in increased surface roughness and a higher quantity of MNPs on the surface. This aging process involves the generation of carbon- and oxygen-centered free radicals, chain scission, and the formation of oxidation products with hydroxyl and carbonyl groups. These MNPs can be released under water shear force, significantly increasing the normalized mass loss of aged films to approximately 0.128 mg/cm2 (18 times higher than that of unaged films in water). In the gastrointestinal environment, the normalized mass loss further increases to about 0.196 mg/cm2 (28 times higher), likely due to potential enzymatic digestion and ion-swelling effects. These MNPs, primarily composed of PLA, are smaller and carry more negative charges under gastrointestinal conditions. In the THP-1 cell model, these MNPs affect cell viability in a dose-dependent manner. MNPs obtained through ultrafiltration, compared to those collected via centrifugation, display a broader size distribution and induce more pronounced toxicity in THP-1 cells, with an EC50 of 243 mg/L. Preliminary comparative analysis indicates that PLA/PBAT-derived MNPs present toxicity risks comparable to, or greater than, those of conventional plastic MNPs. These findings underscore the potential hazards associated with biodegradable plastics.
研究领域:
环境科学
·
材料科学
·
毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2015
·Vol. 5
·期 130
·107949-107956
·
IF 3.84
Xuemin Yu,Zhu Xiong,Jinglong Li,Ziyang Wu,Yunze Wang,Fu Liu
Poly(lactic acid) (PLA) has attracted growing attention as a sustainable and environmentally benign membrane material. The good biocompatibility/hemocompatibility is essential for hemodialysis membranes. To circumvent the inadequate hydrophilicity/biocompatibility/hemocompatibility, we have developed a feasible strategy that enables the persistent PEGylation on PLA membranes via micro-swelling and subsequent UV-initiated crosslinking of poly(ethylene glycol)diacrylate (PEGDA). The content of DMSO and PEGDA in the reaction solution was crucial to control the surface PEGylation kinetics. Besides, the influence of PEGylation on membrane chemistry, morphology, hydrophilicity, water flux and dynamic fouling resistance to BSA was investigated. It was demonstrated that the biocompatibility/hemocompatibility was significantly improved by the surface PEGylation in terms of reduced BSA adsorption, extended APTT and alleviative platelet adhesion.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
·
2023
·
IF 5.4
Yufang Li,Xiaozhao Tang,Zushun Yang,Jinze He,Ni Ma,Aixiang Huang,Yanan Shi
The combination of natural antimicrobial peptide BCp12/phenyllatic acid (BCp12/PLA) presents a more efficient antibacterial effect, but its antibacterial mechanism remains unclear. This study studied the synergistic antibacterial mechanism of BCp12 and PLA against S. aureus . The results demonstrated that the BCp12/PLA combination presented a synergistic antibacterial effect against S. aureus , with a fractional inhibitory concentration of 0.05. Furthermore, flow cytometry and scanning electron microscope analysis revealed that BCp12 and PLA synergistically promoted cell membrane disruption compared with the group treated only with one compound, inducing structural cell damage and cytoplasmic leakage. In addition, fluorescence spectroscopy analysis suggested that BCp12 and PLA synergistically influenced genomic DNA. BCp12 and PLA targeted enzymes related to peptidoglycan and DNA synthesis and interacted by hydrogen bonding and hydrophobic interactions with mur enzymes (murC, murD, murE, murF, and murG), dihydrofolate reductase, and DNA gyrase. Additionally, the combined treatment successfully inhibited microbial reproduction in the storage of pasteurized milk, indicating that the combination of BCp12 and PLA can be used as a new preservative strategy in food systems. Overall, this study could provide potential strategies for preventing and controlling foodborne pathogens.
研究领域:
微生物学
·
食品科学
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）