Biosensors-Basel
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2022
·Vol. 12
·期 10
·802
·
IF 5.743
Sisi Yang,Ziwen Tang,Yilong Tian,Xinghu Ji,Fubing Wang,Conghua Xie,Zhike He
Since it is difficult for human eyes to distinguish between two identical colors with only <15% variation in brightness, mono-color fluorescent hydrogel microspheres have some limitations in the detection of lactate. Herein, we prepared novel dual-color fluorescent hydrogel microspheres, which can achieve hue transformation. Microspheres were prepared by introducing a fluorescent nanoparticle as the reference signal while CdTe QDs were used as the response signal. We used smartphones with image processing software to collect and analyze data. In this way, the signal of lactate was converted to RGB (red, green, and blue) values, which can be quantitatively read. Within 10 to 1500 μM, the R/G values of the microspheres had a linear relationship with the logarithm of the lactate concentration. Moreover, color cards for lactate detection were prepared, from which the color change and concentration of lactate could be easily read by the naked eye. It is worth mentioning that this method was successfully applied to screen patients with hyperlactatemia.Keywords:lactate detection;semiconductor quantum dots (QDs);fluorescent nanoparticles;hydrogel microspheres;visual detection
研究领域:
生物化学
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医学诊断
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材料科学
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DOI
PubMed
高影响因子
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
·
2012
·Vol. 14
·期 47
·16258-16266
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IF 3.573
Yonghai Song,Dan Luo,Shuhong Ye,Mei Huang,Dandan Zhong,Zhenzhong Huang,Haoqing Hou,Li Wang
Water-soluble fluorescent quantum dots (QDs) have been widely used in biological and biomedical fields, and the interaction between QDs and proteins and the conformational structure of the protein in the bioconjugate has attracted increasing attention. In this study, UV-Vis spectroscopy, fluorescence quenching, CD spectra, gel electrophoresis and Fourier transform infrared (FTIR) spectroscopic techniques were used to systematically investigate the interaction between type II restriction endonuclease (EcoRI) and CdS QDs and the conformational structure of EcoRI in the EcoRI-CdS QDs bioconjugates. The results indicated that electrostatic interactions played a major role in the binding reaction at pH 6.0, and the nature of quenching was static, resulting in forming CdS QDs–EcoRI bioconjugates. FTIR and CD spectra studies indicated a decrease of α-helical and turn structures accompanied by the increase of β-sheet structures of EcoRI in the bioconjugates. This study showed that the interaction between EcoRI and CdS QDs resulted in a change in the secondary structure of EcoRI after it was conjugated with CdS QDs, but the enzyme activity was maintained.
研究领域:
生物物理
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生物化学
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纳米生物技术
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分子生物学
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DOI
PubMed
高影响因子
Soft Matter
·
2019
·Vol. 15
·期 11
·2319-2327
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IF 3.399
Na Qi,Hui Zhao,Qiaozhi Wang,Yan Qin,Hao Yuan,Ying Li
Quantum dots (QDs) are of great interest due to their excellent fluorescence properties and thus, they have been widely studied. Compared with the typical organometallic synthetic routes and hydrothermal methods usually carried out under high temperatures, methods employing colloidal templates can be used for preparing QDs in mild conditions and have gained increasing attention. In this prospect, a hydrogel is an ideal colloidal template for the preparation of QDs in an aqueous medium, while the related study for in situ preparation of QDs in a gel and the consequent functionalization of QDs are in demand. In this paper, we proposed a two-step method to prepare CdS QDs in a sodium alginate (SA) gel, which showed effective constraint in the uniform size distribution of QDs. Without the introduction of additional ligands, the prepared CdS–SA QDs exhibited responsiveness to pH and detection of Fe3+, thus providing a simplified way for the functionalization of QDs. CdS–SA QDs showed good biocompatibility and stability in a certain concentration, which indicated the prospective applications of CdS–SA QDs in the fields of biological labeling and environmental sensing.
研究领域:
材料科学
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纳米技术
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生物医学工程
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环境科学
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产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2017
·
IF 5.401
Xiao Wei,Guodan Xu,Chengcheng Gong,Fang Qin,Xinghui Gong,Chen Li
In this paper, we have presented a custom-tailored strategy to fabricate molecularly imprinted composite sensors (MIPs/QDs@SiO 2 ) with highly selective recognition ability for the determination of sulfanilamides (SAs). The modified SiO 2 sphere, modified QDs, acrylamide (AM), and ethyl glycol dimethacrylate (EGDMA) were used as the supporter, the fluorescent material, the functional monomer , and the cross-linker, respectively. Afterward, a two-step imprinting polymerization reaction was implemented to fabricate the novel sensor MIPs/QDs@SiO 2 . Attributing to the SiO 2 with the surface functional monomer and the QDs with functional group, SAs molecules are attracted to the QDs and bound to the SiO 2 surface, hence accelerating the growth of homogeneous recognition sites on the surface of SiO 2 and guaranteeing the distance between the recognition sites and the QDs. After the experimental conditions were optimized, such fluorescence sensors can be used for well selective detection of SAs with a linear range of 2.0–30 μmol/L and a limit of detection is 0.17 μmol/L. Most importantly, the MIPs/QDs@SiO 2 can be successfully applied to the determination of SAs in real river water, which demonstrate high selectivity and stability and offer a promising platform for detecting environmental pollutants.
研究领域:
分析化学
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环境科学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF THE INDIAN CHEMICAL SOCIETY
·
2025
·
IF 3.4
Qi Shi,Siqi Huang,Qi Xi,Yanan Niu,Nuan Wen,Libo Du,Yuguang Lv,Tai Peng
In this study, Ti 3 C 2 quantum dots (QDs) were prepared via a simple hydrothermal method and loaded onto binary catalytic materials to construct ternary PTCN/SnS 2 /Ti 3 C 2 QDs composites for enhancing photocatalytic performance. The materials were characterized using techniques such as XRD, TEM, FT-IR, UV–vis, BET, XPS, and PL. The results showed that Ti 3 C 2 QDs were uniformly dispersed on the surface of PTCN/SnS 2 , forming a stable heterostructure. The specific surface area increased to 68.847 m 2 /g (5.6 times higher than that of PTCN), the visible light absorption edge redshifted to 532 nm, and the band gap narrowed to 2.1 eV. Under visible light, the composite exhibited degradation rates of 90.53 %, 79.53 %, 81.23 %, and 85.62 % for norfloxacin, pefloxacin, enrofloxacin, and ciprofloxacin, respectively. At the optimal doping amount (k = 0.0408 min −1 ), the catalytic activity was 6.21 times that of pure PTCN and 2.87 times that of PTCN/SnS 2 . Cyclic experiments demonstrated excellent stability of the composite, with a degradation rate remaining at 86 % after 5 cycles. This study is the first to construct the PTCN/SnS 2 /Ti 3 C 2 QDs ternary system and propose a Z-scheme charge transfer mechanism, providing new insights for the design of high-efficiency photocatalytic materials.
研究领域:
材料科学
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环境科学
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纳米技术
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催化
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化学工程
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产品关联
DOI
高影响因子
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
·
2016
·Vol. 16
·期 6
·6338-6343
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IF 1.338
Du Yingying,Yang Ping,Liu Yunshi,Zhao Jie,He Haiyan,Miao Yanping
TiO2 films consisted of small nanoparticles were fabricated via a spinning coating method on fluorine doped in tin oxide (FTO) slide glass. After calcination, the films were subsequently sensitized by CdSe quantum dots (QDs) using mercaptopropionic acid (MPA) as a bifunctional
surface modifier. Upon UV light irradiation, CdSe QDs inject electrons into TiO2 nanoparticles, thus resulting in the generation of photocurrent in QD-sensitized solar cell. The results indicate that TiO2 films sensitized by CdSe QDs have achieved 1.5-fold enhancement
in photocurrent compared with pure TiO2 films, indicating that CdSe QDs can improve the photocurrent by promoting the separation of photoinduced charge carriers. In addition, the photocurrent enhances as the thickness of TiO2 films increased. Such improved photoelectrochemical
performance is ascribed to the basis of improved interfacial charge transport of the TiO2-CdSe composite films. Combining QDs on TiO2 thin films is a promising and effective way to enhance the photoelectrochemical performance, which is important in QD-sensitized solar
cell application.
研究领域:
材料科学
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纳米技术
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太阳能
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光化学
✓ 已验证
DOI
PubMed
高影响因子
Journal of Materials Chemistry C
·
2016
·Vol. 4
·期 28
·6720-6726
·
IF 5.066
Xiaolong Lu,Rongguo Wang,Fan Yang,Weicheng Jiao,Wenbo Liu,Lifeng Hao,Xiaodong He
Lots of top-down approaches by weakening the van der Waals interaction between adjacent layers and breaking up the covalent chemical bonds in each layer have been reported to prepare QDs of layered materials due to the stacked structures. However, much attention has been focused on graphene and layered transition-metal dichalcogenides (TMDs), seldomly on layered transition-metal oxides (TMOs). Herein, a modified top-down method combining intercalation and thermal exfoliation is reported to prepare high-yield QDs of layered MoO3. Alkylamine was first intercalated into MoO3 layers to weaken the van der Waals forces. Then, the covalent bonds in each MoO3 layer were broken down under a sudden increase in gas pressure generated by the decomposition of alkylamines after rapid heating. These fractured particles were further incised to QDs by sonication. The as-prepared MoO3 QD dispersion showed a plasmon resonance after simulated solar light illumination. Surprisingly, their plasmon peak red shifted with an extended illumination time, which was different from the reported MoO3 nanosheets. This reported method is expected to extend to other QDs of layered materials providing that their bulk materials can also be intercalated.
研究领域:
材料科学
·
纳米技术
✓ 已验证
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2022
·
IF 10.383
Zhenyu Wang,Xinyu Shen,Chengyuan Tang,Xin Li,Junhua Hu,Jinyang Zhu,William W. Yu,Hongwei Song,Xue Bai
Oleylamine and oleic acid are common organic capping ligands used in the hot injection preparation of perovskite quantum dots (QDs). Their labile nature is responsible for the poor colloidal stability and conductivity that affect the performance of perovskite QD light-emitting diodes (LEDs). We introduced 4-trifluoro phenethylammonium iodide (CF3PEAI) directly in the synthesis and found that CF3PEAI efficiently modified the I– vacancy defects on the QD surface and partially substituted the surface capping ligand oleylamine. The strong electron pulling ability of F in CF3PEAI results in a more positive −NH3+ terminal compared to that of PEAI, which promotes tight bonding of CF3PEAI on the surface of CsPbI3 QDs. As a result, we achieved bright QDs with a photoluminescence quantum yield of 92% and efficient red LEDs. The maximal luminance was improved to 4550 cd m–2 for 685 nm red light, which was nearly 4.6-fold of the LEDs with plain CsPbI3 QDs. Additionally, the peak external quantum efficiency reached 12.5%.
研究领域:
材料科学
·
光电技术
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产品关联
DOI
PubMed
高影响因子
ACS Applied Electronic Materials
·
2023
·
IF 4.7
Yubo Peng,Xudong Jin,Pingjun Zeng,Min Zhao,Zhipeng Gao,Jian-long Ji,Xiaona Li,Weiyi Chen
Recently, artificial photosynapses have attracted much attention from researchers because they have the ability to perceive, process, and remember information about the external environment, which can greatly improve the efficiency of visual information processing. This work prepared the artificial optical synaptic transistors based on organic electrochemical transistors (OECTs) and CsPbBr3 quantum dots (QDs) synthesized at room temperature. The fabricated device here could successfully imitate the visual functions by mimicking the important synaptic features such as excitatory postsynaptic currents, paired-pulse facilitation, spiking-rate-dependent plasticity, spiking-number-dependent plasticity, and short-term memory to long-term memory transition. Employing the device, we also simulated the capabilities of the human visual system of light adaptation, image recognition, and preprocessing. The investigations in this work indicated that CsPbBr3 QDs have a high potential application in fabricating artificial photosynapses of the type of OECTs to imitate human vision due to the simpler fabrication process.
研究领域:
神经科学
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材料科学
·
电子工程
✓ 已验证
产品关联
DOI
高影响因子
Progress in Natural Science-Materials International
·
2023
·
IF 4.7
Haiyan Kang,Hongchao Geng,Sisi Shi,Zhongxian Song,Yuting Dong,Xiaole Yan,Chaohai Wang,Yanli Mao,Qingyun Cai
High concentrations of Cu 2+ exceeding what the required level for the cellular process can changes the properties of protein, affects the normal function of the body, but also affect the body's metabolism, so that the body's immunity appears to decline. Detection of Cu 2+ is important for the environmental monitoring. Here, a fluorescence probe that uses heavy metal-free and properties-superior CuInS 2 /ZnS was proposed for detection of Cu 2+ . The fluorescence intensity of CuInS 2 /ZnS quantum dots (QDs) decreased obviously after Cu 2+ were added, and the intensity with the concentration of Cu 2+ showed excellent linear relation within the scope of 0–50 μM, the LOD down to 0.45 μM, a possible detection mechanism was analyzed. The QDs was further applied to the detection of Cu 2+ in drinking water, manifesting the foreground of the current strategy.
研究领域:
生物化学
·
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
Nanomaterials
·
2023
·Vol. 13
·期 16
·2372
·
IF 5.3
Jiaming Wang,Li Zou,Meili Yang,Jiajie Cheng,Yufan Jiang,Guangdong Huang,Jingjing Dong
All-inorganic perovskite quantum dots (CsPbX3QDs) (X = Cl, Br, I) have the advantages of adjustable emission position, narrow emission spectrum, high fluorescence quantum efficiency (PLQY), easy preparation, and elevated defect tolerance; therefore, they are widely used in optoelectronic devices, such as solar cells, light-emitting diodes, and lasers. However, their stability still constrains their development due to their intrinsic crystal structure, ionic exchange of surface ligands, and exceptional sensitivity to environmental factors, such as light, water, oxygen, and heat. Therefore, in this paper, we investigate the stability improvement of CsPbX3QDs and apply fabricated high-efficiency, stable perovskite QDs to solar cells to improve the performance of the cells further. In this paper, we focus on CsPbBr3QDs with intrinsic extreme stability and optimize CsPbBr3QDs using strategies, such as Mn+doping, ligand regulation, and polymer encapsulation, which can improve optical properties while ensuring their stability. The test results show that the above five methods can improve the strength and luminescence performance of QDs, with the best stability achieved when PMMA encapsulates QDs with a ratio of PMMA = 2:1 and PLQY increases from 60.2% to 90.1%.Keywords:perovskite quantum dots;CsPbBr3;PMMA;optical properties;stability
研究领域:
材料科学
·
光电子学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICA CHIMICA ACTA
·
2019
·
IF 5.256
Guangyang Xiao,Beibei Chen,Man He,Bin Hu
Avian influenza virus (AIVs), hosted in poultry, are the pathogens of many poultry diseases and human infections, which bring huge losses to the poultry breeding industry and huge panic to society. Therefore, it is of great significance to establish accurate and sensitive detection methods for AIVs. In this work, a dual-mode detection method based on immuno-rolling circle amplification (immuno-RCA) and quantum dots (QDs) labeling for inductively coupled plasma mass spectrometry (ICP-MS) and fluorescence detection of H9N2 AIV was developed. The dual-mode detection of the QDs by ICP-MS and fluorescence is used to achieve mutual verification within the analysis results, thus improving the accuracy of the method. With the immuno-RCA, the sensitivity of the method was increased by two orders of magnitude. The limit of detection of the proposed method is 17 ng L −1 and 61 ng L −1 , and the linear range of the proposed method is 0.05–5 ng mL −1 and 0.1–5 ng mL −1 with ICP-MS and fluorescence detection, respectively. The relative standard deviation (n = 7) is 4.9% with ICP-MS detection and 3.1% with fluorescence detection. Furthermore, the proposed method was applied to the analysis of chicken serum samples, no significant different was found for two modes detection and the recoveries of the spiking experiments are acceptable, indicating that the method has good practical potential for real sample analysis.
研究领域:
分析化学
·
病毒学
·
生物技术
✓ 已验证
DOI
PubMed
高影响因子
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