ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2017
·Vol. 409
·期 19
·4627-4635
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IF 3.431
Li Hongji,Wang Zirun,Wang Xiaonan,Jiang Jiaqi,Xu Yeqing,Liu Xiqing,Yan Yongsheng,Li Chunxiang
Novel molecularly imprinted polymers (MIPs) based on the technique of surface-enhanced Raman scattering (SERS) were successfully prepared. Firstly, ZnO nanorods were fabricated with Ag by reduction of Ag + on the surface of the ZnO nanorods. Then, ZnO/Ag heterostructures were used as the substrate, rhodamine 6G was used as the template molecule, acrylamide was used as the functional monomer, ethylene glycol dimethacrylate was used as the cross-linker, and 2,2′-azobis(2-methylpropionitrile) was used as the initiator to prepare the ZnO/Ag MIPs (ZOA-MIPs). Through characterization analysis, it was proved that the novel ZOA-MIPs exhibited excellent SERS properties and selectivity. Under the optimal conditions, there was a good linear relationship ( R
2 = 0.996) between the Raman signal (at 1654 cm -1 ) and the concentration of the templates, and the detection limit was 10 -13 mol L -1 . It was also proved that the ZOA-MIPs had the property of self-cleaning, resulting in good reusability. It is envisaged that the sensitivity of SERS coupled with the selectivity of MIPs could result in a promising chemosensor for practical applications.
研究领域:
分析化学
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材料科学
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DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2024
·
IF 4.3
Qinli Ye,Miaomiao Wu,Qian Xu,Shuwen Zeng,Tao Jiang,Wei Xiong,Songyin Fu,Muhammad Danang Birowosuto,Chenjie Gu
The Surface-enhanced Raman scattering (SERS) is an attractive optical detecting method with high sensitivity and detectivity, however challenges on large-area signal uniformity and complex spectra analysis methods always retards its wide application. Herein, a highly sensitive and uniform SERS detection strategy supported by porous carbon film/WO 3-x nanosheets (PorC/WO 3-x ) based noble-metal-free SERS substrate and deep learning algorithm are reported. Experimentally, the PorC/WO 3-x substrate was prepared by high-temperature annealing the PorC/WO 3 films under the argon atmosphere. The defect density of the WO 3 was controlled by tuning the reducing reaction time during the annealing process. The SERS performance was evaluated by using R6G as the Raman reporter, it showed that the SERS intensity obtained on the substrate with the optimal annealing time of 3 h was about 8 times as high as that obtained on the PorC/WO 3 substrate without annealing treatment. And detection limit of 10 -7 M and Raman enhancement factor of 10 6 could be achieved. Moreover, the above optimal SERS substrate was utilized to detect flavonoids of quercetin, 3-hydroxyflavone and flavone, and a deep learning algorithms was incorporated to identify the quercetin. It revealed that quercetin can be accurately detected within the above flavonoids, and lowest detectable concentration of 10 -5 M can be achieved.
研究领域:
材料科学
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分析化学
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光学
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机器学习
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DOI
PubMed
高影响因子
TALANTA
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2018
·
IF 4.244
Kaiqiang Wang,Da-Wen Sun,Hongbin Pu,Qingyi Wei
Plasmonic core-shell nanomaterials have attracted great attention and offered wide applications in surface-enhanced Raman spectroscopy (SERS) due to their unique localized surface plasmon resonance (LSPR) characteristics. In this study, the SERS performance of Ag coated Au nanoparticles aggregates (Au@AgNAs) substrate was explored. The fabrication of Au@AgNAs involved using spherical Au nanocrystals of 32 nm in diameter as the seeds, and ascorbic acid was used as the reductant. The thickness of the Ag shell deposited onto the Au surface was finely tuned from 3 to 13 nm by changing the amount of AgNO 3 precursor. Results in this study suggested that the LSPR of the Au core was rapidly attenuated with increasing Ag shell thickness, while the LSPR bands for Ag shell blue-shifted from 390 to 420 nm. Au@AgNAs with the Ag shell thickness of 8.5 nm exhibited excellent SERS activity, which could realize detecting R6G at an ultralow concentration of 1 × 10 −12 M. Besides, the prepared Au@AgNAs showed well homogeneity and reproducibility, and the limit of detection of thiram was calculated as 1.09 × 10 −9 M, indicating that the Au@AgNAs substrate could be potentially used for high-performance SERS sensing applications.
研究领域:
纳米材料科学
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光学
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分析化学
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DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
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2020
·
IF 6.182
Yingshuang Song,Yusi Peng,Nguyen Viet Long,Zhengren Huang,Yong Yang
At present, there is an urgent need to develop a highly efficient adsorbent and photocatalyst with photodegradability under visible light for the removal of dye molecules in wastewater. Herein, the multifunctional three-dimensional Ag/g-C 3 N 4 /reduced graphene oxide aerogel (Ag/g-C 3 N 4 /RGOA) has been successfully prepared by a simple “one-pot” hydrothermal method , which exhibits three kinds of improved properties including excellent surfaced-enhanced Raman scattering (SERS) activity, highly efficient adsorption and photocatalytic activity. The composite aerogel presents 3D porous network structure. Importantly, the composite aerogel exhibits excellent adsorption and photocatalytic performance with adsorption rate of 44% and degradation rate of 93%. This is mainly attributed to the synergistic effect of Ag NPs, g-C 3 N 4 and RGO, which promotes the separation of photogenerated electrons and holes. In addition, the 3D porous network structure is conducive to the utilization of visible light and the transfer of photogenerated electrons. Furthermore, Ag/g-C 3 N 4 /RGOA exhibits excellent SERS activity with a detection limit of 1 × 10 −7 M for R6G molecules. The SERS performance has been utilized to monitor the process of adsorption and photodegradation of R6G by the composite aerogel. In this research, the designed multifunctional aerogel may become an attractive material for the detection and removal of dyes in wastewater.
研究领域:
环境科学
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材料科学
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DOI
高影响因子
ACS Sensors
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2024
·
IF 8.2
Chunning Chen,Jiaqi Liu,Jiaxin Lu,Yalei Wang,Jingtong Zhai,Hongkun Zhao,Nan Lu
As one of the common carriers of biological information, along with human urine specimens and blood, exhaled breath condensate (EBC) carries reliable and rich information about the body’s metabolism to track human physiological normal/abnormal states and environmental exposures. What is more, EBC has gained extensive attention because of the convenient and nondestructive sampling. Facemasks, which act as a physical filter barrier between human exhaled breath and inhaled substances from the external environment, are safe, noninvasive, and economic devices for direct sampling of human exhaled breath and inhaled substances. Inspired by the ability of fog collection of Namib desert beetle, a strategy for in situ collecting and detecting EBC with surface-enhanced Raman scattering is illustrated. Based on the intrinsic and unique wettability differences between the squares and the surrounding area of the pattern on facemasks, the hydrophilic squares can capture exhaled droplets and spontaneously enrich the analytes and silver nanocubes (AgNCs), resulting in good repeatability in situ detection. Using R6G as the probe molecule, the minimal detectable concentration can reach as low as 10–16 M, and the relative standard deviation is less than 7%. This proves that this strategy can achieve high detection sensitivity and high detection repeatability. Meanwhile, this strategy is applicable for portable nitrite analysis in EBC and may provide an inspiration for monitoring other biomarkers in EBC.
研究领域:
分析化学
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生物医学工程
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环境科学
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DOI
PubMed
高影响因子
MICROCHIMICA ACTA
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2019
·Vol. 186
·期 2
·1-9
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IF 5.479
Yao Li,Li Yulin,Cheng Kewen,Pan Daodong,Xu Jianguo,Chen Wei
The authors describe an aptamer-based assay for 17β-estradiol. It relies on the combined use of surface enhanced Raman scattering (SERS) and hybridization chain reaction (HCR). The aptamer against 17β-estradiol is applied as the recognition probes, and this results in excellent specificity. Specific recognition of target 17β-estradiol induce the freedom of DNA 2, which will open the stem-loop structure of probe 1 on the Au@Ag and form the partial dsDNA structure. With the nicking enzyme, the partial dsDNA will be hydrolyzed and the reside ssDNA on Au@Ag will form a small stem-loop structure. With the help of the other probe 2 modified Au@Ag and pre-immobilized probe 3 on the well of the microplate, an enzyme-free HCR can occur and tremendous Au@Ag can be assembled along the formed dsDNA in HCR, which can act as the excellent substrate for Raman measurement and greatly amplify the Raman signal of R6G on the Au@Ag. Afterwards, the key factor, ratio between probe 2-Au@Ag (P2) and probe1-Au@Ag (P1), affects the detection sensitivity is systematically optimized for the best sensing performance. The SERS signal of R6G, best measured at 1651 cm −1 , increases linearly in the wide range from 1 pM to 10 nM. The detection limit can be as low as 0.1 pM.
Schematic presentation of an aptamer-based surface enhanced Raman scattering method for accurate detection of 17β-estradiol, which is integrated with hybridization chain reaction for signal amplification and sensitivity improvement.
研究领域:
分析化学
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纳米技术
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生物传感器
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分子诊断
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产品关联
DOI
PubMed
高影响因子
Materials
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2018
·Vol. 11
·期 2
·247
·
IF 2.467
Quanguo He,Jun Liu,Jing Liang,Xiaopeng Liu,Du Tuo,Wen Li
Solubility parameter-dependent drug releasing property is essential in practical drug delivery systems (DDS), and how to combine magnetic nanoparticles(NPs) and suitable polymer coating towards DDS is always a crucial and valuable challenge in biomedical application. Herein, a controllable drug delivery model with a surface having a chemically tunable solubility parameter is presented using hollow magnetite/polyacrylic acid (Fe3O4/PAA) nanocomposites as nanocarrier towards DDS. This composite is prepared by simply coating the modified hollow Fe3O4with PAA. The coating amount of PAA onto the surface of Fe3O4(measured by TGA) is about 40% (w/w). Then, Rhodamine 6G (R6G) is selected as model drug in drug delivery experiment. The efficiency of drug loading and drug release of these Fe3O4/PAA nanocarriers are evaluated under various temperature, solvent and pH values. As a result, the best drug releasing rate was achieved as 93.0% in pH = 7.4 PBS solution after 14 h. The releasing efficiency is 86.5% in acidic condition, while a lower releasing rate (30.0%) is obtained in aqueous solution, as different forms (polyacrylic acid and polyacrylate) of PAA present different solubility parameters, causing different salt and acid effects in various solvents, swelling property of PAA, and binding force between PAA and R6G. Therefore, by changing the solubility parameter of coating polymers, the drug delivery properties could be effectively tuned. These findings prove that the DDS based on magnetic particle cores and polymer encapsulation could efficiently regulate the drug delivery properties by tuning surface solubility parameter in potential cancer targeting and therapy.Keywords:hollow Fe3O4NPs;Fe3O4/PAA composite NPs;solubility parameter;controlled release;drug delivery systems
研究领域:
材料科学
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生物医学工程
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药学
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DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2017
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IF 4.233
Hongji Li,Jiaqi Jiang,Zirun Wang,Xiaonan Wang,Xiqing Liu,Yongsheng Yan,Chunxiang Li
A novel, sensitive sensor material combined the technique of surface enhance Raman scattering (SERS) and molecular imprinting was prepared. It was used the amino-functionalized SiO 2 nanospheres as the supporting materials and anchored Ag nanoparticles on the surface by the function of coordination between Ag + and NH 2 − . Then, it was used that the Rhodamine 6G (R6G) as the template, acrylamide (AM) as functional monomer, ethyleneglycol dimethacrylate (EGDMA) as cross-linker, 2,2′-azobis(2-methylpropionitrile) (AIBN) as initiator to prepare the core-shell molecular imprinted polymers. Prominently, the shell thickness could be controlled by the regulation of cross-linker dosage and it was found that the SERS detection signal was most obvious when the shell thickness was about 40 nm. Under the optimal condition, it was presented good linear relationship (R 2 = 0.93) between the Raman signal (at 1505 cm −1 ) and the concentration of the templates and the limit of detection was 10 −12 mol L −1 . Meanwhile, the selective experiment was proved that this materials owned specific selectivity to the template. It was confirmed that the core-shell molecular imprinted polymers were a kind of highly sensitive and selective sensor materials in the field of R6G detection.
研究领域:
分析化学
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材料科学
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环境科学
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产品关联
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2023
·Vol. 190
·期 10
·1-9
·
IF 5.7
Yang Weiqing,Li Dandan,Li Yunlong,Zheng Yuan,Shan Jiajia
Abstract A method is proposed to fabricate a novel capillary surface-enhanced Raman scattering (SERS) substrate integrating sampling and detection based on meniscus evaporation self-assembled technology, named Meniscus@AgNPs@Capillary substrate. Ag nanoparticles (AgNPs) were arranged in the inner wall of the capillary through meniscus evaporation. The parameters which might affect the deposition of AgNPs during evaporation were investigated, including the evaporation temperature, self-assembly time, the ratio of silver sol to ethanol, and capillary length. The enhancement effect of SERS under different fabrication conditions was investigated using rhodamine 6G (R6G) as a Raman probe. Moreover, the optimal fabricated Meniscus@AgNPs@Capillary substrate was applied to the detection of several environmental pollutants such as polystyrene nanoplastics (PSNPs) and various antibiotics, with limits of detection (LOD) of 10 µg/L and 1 µg/L, respectively. The Meniscus@AgNPs@Capillary substrate presented the advantages of time and effort saving, high sensitivity, and on-site sampling and testing. Graphical Abstract
研究领域:
材料科学
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分析化学
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环境科学
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产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2023
·
IF 4.4
Yahui Zhang,Xia Huang,Jiachang Chen,Jiyuan Li,Junying Chen
A convenient and reliable surface-enhanced Raman scattering (SERS) substrate has been developed for the surface corrosion analysis of bronze artifacts. The substrate consists of oriented alginate nanofiber membranes containing silver nanoparticles (Ag NPs), which were obtained through electrostatic spinning, ion exchange, and in-situ reduction. By controlling the reduction time, Ag/alginate nanofiber membranes with different contents, sizes, and distributions were obtained. The Ag/alginate nanofiber#20 membranes, obtained with a reduction time of 20 min, reached a detection limit of 10 −12 M for R6G with an enhancement factor of 6.64 × 10 7 . In the trace detection of bronze patina, the intensity of the characteristic peaks of harmful patina located at 513, 846, 911, and 974 cm −1 were increased by more than 500 %. This was due to the uniform loading of a large number of Ag NPs on the surface of the nanofiber membrane obtained by reduction for 20 min, and the formation of a large number of hot spots between the oriented nanofibers. This significantly improved the SERS performance of the flexible substrate layer under the joint action with the Ag NPs. These results indicate that the flexible substrate layer can greatly enhance the Raman characteristic peaks of alkali copper chloride and be effectively used for trace analysis of the surface composition of bronze artifacts.
研究领域:
材料科学
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纳米技术
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文化遗产保护
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分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2023
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IF 4.4
Feng Lu,Xinhuan Xu,Xingdong Zhu,Linxin Shen,Weizheng Wan,Min Hu
Room temperature phosphorescent (RTP) Carbon Dots have been capturing increasing attention in recent years, while building a general method to adjust the emission color of RTP carbon dots is still a big challenge. Herein we report a simple method that combine the carbon nanodots and dyes (R6G and DCF) in SiO 2 nanosphere to get a series of multicolor RTP nanodots (CD@SiO 2 @dye) with long lifetime in aqueous solution. Leverage on chitosan quaternary ammonium as matrix and diethylenetriamine as N-doping resource to form a cross-linked skeleton as a luminescent center (namely CD), and a rigid network is formed by silica encapsulation (CD@SiO 2 ) to restrict the non-radiative transition process to generate the phosphorescence. The CD-based composites, with 1.10 s green (503 nm) phosphorescence emission, serve as activator to stimulate the corresponding luminescence of organic dyes. Then, based on Förster resonance energy transfer (FRET) process from CDs (as donor) to organic dyes (as acceptor) under UV excitation, the CD@SiO 2 @R6G emit ultra-long lifetime (1.13 s) orange-yellow (570 nm) afterglow, and CD@SiO 2 @DCF emit ultra-long lifetime (1.20 s) yellow-green afterglow (530 nm). Furthermore, it also achieves RTP colors control when the ratio of CDs and the dyes changes, the ratio of green emission and dye’s emission activated by CDs will gradually change as well. These kinds of materials keep the inherent advantages of low toxicity and luminous stability, and achieve adjustable RTP color in aqueous solution. Our research provides a strategy to synthesize water-soluble long-life RTP CDs with adjustable color and lifetime.
研究领域:
材料科学
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纳米技术
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光化学
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分析化学
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产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2014
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IF 4.058
Jiale Huang,Dengpo Huang,Yi Liu,Huimei Chen,Xiaolian Jing,Daohua Sun,Qingbiao Li
Gold recovery is of practical significance while functional Au nanostructures are of great interest in modern nanotechnology. In this work, highly and hierarchically branched Au nanowires (AuNWs) were produced to obtain bio-AuNW composites while the Au was effectively recovered from aqueous HAuCl 4 solution by a microorganism-mediated, surfactant-directed (MSD) approach with Lactobacillus spp. cells (LSCs). Ternary coordination of the cell-surfactant-AA played an important role in recovering Au and producing the bio-AuNW composites in the cases of tetradecyl trimethyl ammonium bromide (TTAB), hexadecyltrimethylammonium bromide (CTAB) and octadecyl trimethyl ammonium bromide (OTAB). In contrast, Au recovery could not be achieved with hexadecyltrimethylammonium chloride (CTAC). Strong interaction between [AuCl 4 ] − and the LSCs prior to addition of surfactant (except CTAC) and ascorbic acid (AA) was vital for the highly and hierarchically branched nanostructures. Furthermore, the bio-AuNW composites could serve as excellent surface-enhanced Raman spectroscopy (SERS) substrate. the SERS detection limits of toxic rhodamine 6G (R6G) and 4-mercaptobenzoic acid (MBA) with the bio-AuNW composites are down to 10 −9 and 10 −6 M, respectively. This work therefore exemplifies combining recovery of Au and fabrication of functional Au nanomaterials, which was environmentally benign and application-oriented.
研究领域:
环境科学
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纳米技术
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材料科学
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生物技术
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）