JOURNAL OF THE ELECTROCHEMICAL SOCIETY
·
2019
·Vol. 166
·期 2
·B13
·
IF 3.12
Meiling Wang,Huifang Shi,Mingzhu Cui,Weifeng Liu,Xuguang Liu
A "green nano" strategy was extended to prepare monodisperse polypyrrole (PPy) nanospheres with tunable sizes via simply adjusting pyrrole monomer's concentration. And a linear model was obtained and used to predict the diameter of PPy nanosphere. Nitrogen-doped carbon nanospheres (NCSs) with well-controlled diameters were further synthesized through direct carbonzilation of harvested PPy nanospheres, which demonstrated a facile route for the preparation of highly dispersible NCSs with controlled sizes. Then the potential electrochemical response of as-fabricated NCSs toward food additive-Sunset yellow (SY) was explored. NCSs with medium size (M-NCSs) showed the best electrochemical performance and an ultra-high sensitivity of 679.16 A M−1 cm−2 and lower detection limit of 0.95 nM were gained. This study therefore provides a facile route to high quality, uniform, and size-controlled PPy nanospheres and NCSs, which are promising to be applied to electrochemical and other fields.
研究领域:
分析化学
·
纳米材料科学
·
食品安全检测
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL SCIENCES
·
2021
·Vol. 37
·期 12
·1749-1755
·
IF 2.081
Yang Fu-Xia,Ma Xiao-Tong,Han Shun-Yu
Sunset yellow (SY) is a synthetic colorant which can cause allergies, diarrhea and other symptoms in sensitive people. When ingested too much, it can accumulate in the body and cause damage to the kidneys and liver. Therefore, the content of SY in food must be strictly controlled. In order to regulate their use and ensure food quality, simple and cost-effective methods need to be developed to identify them. In this experiment, fluorescent silicon nanoparticles (SiNPs) were prepared by a one-step method, which is simple, mild and less time-consuming. The fluorescent SiNPs prepared had good thermal stability, excellent salt resistance and pH stability. SY effectively quenched the fluorescence of SiNPs by fluorescence resonance energy transfer when added to the system as an interfering substance. The method had a good linear relationship in the range of SY concentration of 0.050–14.0 μg mL –1 and the detection limit is 0.023 μg mL –1 . The established sensor was applied to the detection of SY in beverages, and the recovery rate was 93.8–102.4%. Based on the excellent selectivity and sensitivity of the method, it could provide a convenient way for the detection of SY in food samples.
研究领域:
分析化学
·
食品科学
·
纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF APPLIED TOXICOLOGY
·
2020
·Vol. 41
·期 6
·953-963
·
IF 2.997
Xiunan Kong,Xiu Wang,Yumei Qin,Jianzhong Han
Sunset yellow (SY), an azo dye, is commonly used in the food industry. The scientific literature contains little information regarding the effects of SY on small intestinal epithelial cells (IECs). In this study, a small intestinal organoid model was used in in vitro toxicological studies of SY, and intestinal inflammatory responses in vivo to SY were investigated with the dextran sulfate sodium (DSS)-induced intestinal inflammation model in C57BL/6 mice. The intestinal organoids were cultured with 2 μg/ml SY for two generations, the growth rates were analyzed, and the expressions of cell lineages were assayed. For inflammatory responses, mice were fed with a diet containing 40 mg/kg diet SY and treated with 2.5% DSS for 7 days. The results showed that SY inhibited the growth of the organoids by inhibiting the proliferation and disturbing the differentiation of IECs. Furthermore, endoplasmic reticulum (ER) stress and oxidative stress levels were elevated in SY-treated organoids. In DSS-treated mice, the disease activity index and expression levels of interleukin-1β and tumor necrosis factor-α were enhanced in the SY group, concluding that SY exacerbated DSS-induced intestinal inflammation. Taken together, these findings revealed that SY could disturb the homeostasis of the small intestinal epithelium by generating high levels of ER stress and oxidative stress, with long-term continuous consumption of SY potentially increasing the risk of intestinal inflammation.
研究领域:
毒理学
·
胃肠病学
·
细胞生物学
✓ 已验证
DOI
PubMed
高影响因子
Desalination and Water Treatment
·
2024
·
IF 1
Jingshuang Fan,Yunxiafei Ling,Chao Gao,Haixia Lyu
A high specific surface area amine-modified polymer of intrinsic microporosity (NH 2 -PIM-1) was synthesized by reducing nitriles to amines in the polymer of intrinsic microporosity (PIM-1) as an adsorbent to remove sunset yellow FCF (SY) from aqueous solution. The physicochemical properties of NH 2 -PIM-1 were characterized by infrared spectra (IR), scanning electron microscope (SEM), thermogravimetric analysis (TGA), nuclear magnetic resonance (NMR) and N 2 adsorption-desorption isotherms measurement. The effect of initial solution pH value, dosage of adsorbent, contact time and initial SY concentration were systematically investigated. The sunset yellow FCF adsorption equilibrium was attained after 10 min and the adsorption capacity could reach 348.16 mg/g, which was superior to most of the other adsorbents previously reported. Kinetics and isothermal model experiments indicated that the adsorption of sunset yellow matched the pseudo-second-order kinetic model and Langmuir model, respectively. Thermodynamic analysis showed that the adsorption was endothermic, spontaneous and physical adsorption process. These results suggested that the NH 2 -PIM-1 was a rapid and efficient kind of adsorbent for removal of sunset yellow FCF.
研究领域:
环境科学
·
高分子化学
·
吸附分离
·
水处理技术
·
物理化学
·
材料科学
✓ 已验证
DOI
高影响因子
Chemosensors
·
2025
·Vol. 13
·期 9
·330
·
IF 3.7
Zihui Li,Wenxue Chen,Qiongya Wan,Haoliang Li,Xuefeng Wang,Pengcheng Xu,Yuan Zhang,Yongheng Zhu,Xinxin Li
This study presents a highly sensitive non-enzymatic electrochemical sensor for detecting Sunset Yellow, a common food additive in beverages, based on palladium-cerium oxide composite decorated carbon black (CB). The sensing material was prepared by depositing palladium nanoparticles onto cerium oxide nanocubes, followed by the uniform dispersion of CB through sonication in a water bath. The strong metal–support interaction between palladium and cerium oxide significantly enhances catalytic activity, while the CB ensures excellent conductivity and structural support for the catalyst. Under optimized conditions, the sensor exhibits a linear response to Sunset Yellow concentrations in the range from 1 to 100 nM, with a limit of detection (LOD) of 0.056 nM. Additionally, the sensor demonstrates remarkable selectivity and stability. Practical application in real orange juice samples yielded recoveries from 99.11% and 101.34%, confirming its reliability for real-world beverage analysis.
研究领域:
电化学传感
·
食品安全
·
纳米材料
·
分析化学
·
环境监测
✓ 已验证
产品关联
DOI
高影响因子
TALANTA
·
2015
·
IF 3.545
Jianbo Li,Xiaojiao Wang,Huimin Duan,Yanhui Wang,Yanan Bu,Chuannan Luo
A new imprinted material based on β -cyclodextrin/ionic liquid/gold nanoparticles functionalized magnetic graphene oxide has been successfully synthesized and modified to the glassy carbon electrode surface to constructed imprinted electrochemical sensor to detect sunset yellow. The sensitivity and electrochemical response of the electrode can be improved by nanomaterials . The surface morphology and crystal structure of the hybrid nanomaterial has been characterized by scanning electron microscopy, X-ray diffraction, Fourier transform infrared spectroscopy. The electrochemical behaviors of the hybrid nanomaterials based sensor were evaluated through cyclic voltammetry and electrochemical impedance spectroscopy . Under the optimized conditions, the proposed electrochemical sensor showed a fast rebinding dynamics, which was successfully applied to sunset yellow detection with a wide linear range from 5.0×10 −9 to 2.0×10 −6 mol L −1 and a detection limit of 2.0×10 −9 mol L −1 . The electrochemical sensor has been successfully applied in the determination of SY in spiked water samples, mirinda drink and minute maid, and the recoveries for the standards added are 97–105%.
研究领域:
分析化学
·
材料科学
·
食品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Foods
·
2025
·Vol. 14
·期 18
·3221
·
IF 5.1
Yujing Wang,Yiran Wang,Jiaxu Zou,Shuxin Tan,Feiyu Yan,Benxu Yang,Chao Li,Shufen Wu
Sunset yellow (SY) is a synthetic azo dye widely used in food and cosmetics. However, concerns have been raised about its potential health risks, including its nephrotoxicity and genotoxicity, when used in excessive amounts. Illegal addition of SY may cause allergic reactions or genetic damage. Therefore, a rapid method for detecting SY is needed. To develop a rapid detection method for sunset yellow (SY) with the aim of preventing its illegal addition in food, this study utilized agricultural waste asparagus peel (AP) as a carbon source and synthesized amino-functionalized carbon quantum dots (AP-CDs) via a green hydrothermal method. A highly sensitive detection platform was established based on the fluorescence quenching mechanism of AP-CDs in the presence of SY. The microstructure of AP-CDs was characterized using transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), and X-ray photoelectron spectroscopy (XPS). Their optical properties were assessed via ultraviolet–visible absorption spectroscopy (UV-vis) and fluorescence spectroscopy (FS). Furthermore, key experimental parameters affecting SY detection were systematically optimized. Results revealed that the synthesized AP-CDs possessed surface hydrophilic functional groups, including hydroxyl, amide, and carboxyl groups, and were composed of carbon (C), oxygen (O), and nitrogen (N) elements. Optical performance studies demonstrated that AP-CDs exhibited a strong fluorescence emission at 470 nm under 380 nm excitation, with a quantum yield (Φ) of 15.9%. Under the optimized conditions (pH 7.0, 0.5 mg/mL AP-CDs), the fluorescence intensity showed a linear response to the concentration of SY over the range of 0.1 to 100 μM (R2= 0.9929), achieving a detection limit of 0.92 μM. This strategy not only enables sustainable resource utilization but also provides a sensitive and practical approach for food safety monitoring, demonstrating significant potential for real-world applications.
研究领域:
食品科学与技术
·
分析化学
·
纳米材料
·
环境监测
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2024
·
IF 8.5
Qianchun Zhang,Yongxia Ao,Jiaxin Liu,Shan Tang,Fengling Tian,Xiaofang Tian,Xinyu Luo,Meijie Xie
The highly efficient red-emissive carbon dots (R-CDs) were synthesized from citric acid, polyethyleneimine, and benzil via a facile solvothermal process. The R-CDs displayed maximum fluorescence properties at excitation and emission wavelengths of 550 and 631 nm, respectively, which fall within the red wavelength range. Moreover, the R-CDs exhibited a high fluorescence quantum yield of 11.3 %, and this fluorescence was effectively quenched by Sunset Yellow (SY). Consequently, a novel fluorescent probe was developed for SY detection. This probe exhibited a linear range of 0.085–11.31 μg/mL and limit of detection of 0.026 μg/mL. The R-CDs were validated for SY quantification in various food samples, including carbonate beverages, powdered beverage, cider vinegar, fruit flavored drinks, chocolate, and hard candy samples, achieving recovery rates of 91.2–122 % and a relative standard deviation of 1.0–3.5 %. The synthesized R-CDs therefore show promise for application as a probe for the detection of SY in foods.
研究领域:
分析化学
·
食品安全
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF SEPARATION SCIENCE
·
2016
·Vol. 39
·期 8
·1559-1566
·
IF 2.741
Yu Zhang,Zhihai Xie,Xiaoxiao Teng,Jin Fan
Novel molecularly imprinted polymer nanoparticles were synthesized by precipitation polymerization with sunset yellow as the template and [2-(methacryloyloxy)ethyl] trimethylammonium chloride as the functional monomer. The molecularly imprinted polymer nanoparticles were characterized by Fourier transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, and their specific surface area and thermal stability were measured. The molecularly imprinted polymer nanoparticles had a high adsorption capacity in wide pH range (pH 1–8) for sunset yellow. The adsorption equilibrium only needed 5 min, and the quantitative desorption was very fast (1 min) by using 10.0 mol/L HCl as the eluant. The maximum adsorption capacity of the molecularly imprinted polymer nanoparticles for sunset yellow was 144.6 mg/g. The adsorption isotherm and kinetic were well consistent with Langmuir adsorption model and pseudo-second-order kinetic model, respectively. The relative selectivity coefficients of the molecularly imprinted polymer nanoparticles for tartrazine and carmine were 9.766 and 12.64, respectively. The prepared molecularly imprinted polymer nanoparticles were repeatedly used and regenerated ten times without significant absorption capacity decrease.
研究领域:
材料科学
·
食品科学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD AND CHEMICAL TOXICOLOGY
·
2022
·
IF 5.572
Ruijuan Lv,Ruimeng Sun,Ting Du,Yuhan Li,Lixia Chen,Yang Zhang,Yanfei Qi
A sensitive electrochemical sensor for sunset yellow (SY) was constructed based on cetyltrimethylammonium bromide (CTAB) functionalized graphene (Gr) and Cu/Zr-MOF electrode modified materials. The CTAB-Gr-Cu/Zr-MOF composites were synthesized by using a mild method and characterized by scanning electron microscopy, Fourier transform infrared spectroscopy and EDX spectrum. The combination of Cu/Zr-MOF and graphene exhibited synergetic effect of the strong accumulation efficiency, fast electron transfer rate and more sensing sites towards the oxidation of SY. The new modified materials remarkably increased the electrochemical response of SY to 6.53-fold when comparing with bare electrode. Under the optimized conditions, the oxidation peak currents of SY had a linear relationship with its concentration in a wide range from 0.10 to 8.00 μM and 40.00–1000.00 μM, and the limit of detection was 6.68 nM (S/N = 3). The electrochemical method shows high sensitivity, stability, reproducibility and is successfully applied in the determination of SY in soft drinks.
研究领域:
分析化学
·
食品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Yuhong Li,Yixian Zhao,Caiyu Ge,Pengcheng Zhao,Junjie Fei,Yixi Xie
Sunset Yellow (SY), a widely utilized synthetic food colorant, poses potential health risks upon excessive consumption. This work reports an ultrasensitive electrochemical sensor for the quantification of SY in commercial beverages. A spherical hierarchical porous carbon composite embedded with FeCo alloy nanoparticles (FeCo@HPC) was synthesized via sequential hydrothermal carbonization and pyrolysis. Density functional theory (DFT) simulations confirm that FeCo bimetallic synergy enhances interfacial electron transfer kinetics, while the hierarchical porous architecture and nitrogen-doped defect sites cooperatively facilitate SY adsorption and electrocatalytic conversion. The sensor demonstrates a linear response across 0.005–6 μM SY, achieving a detection limit of 2.1 nM (S/N = 3) and sensitivity of 23.6 μA·μM −1 . Validation via high-performance liquid chromatography (HPLC) yielded recovery rates of 97.2–103.5 % in spiked beverage matrices. This study establishes a cost-effective analytical platform for food additive surveillance while elucidating design principles for bimetallic carbon-based electrocatalysts.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2017
·
IF 4.529
Daofeng Qu,Yanpei Gu,Lifang Feng,Jianzhong Han
Foods contain various additives that affect our daily lives. At present, food additive safety evaluation standards are based on the toxicity of single additives, but food additives are often used in combination and may have additive, synergistic or antagonistic actions. The current study investigated the toxicity of food additives and mechanisms of damage in HepG2 cells using High Content Analysis (HCA). We used the CCK-8 assay to determine cell viability, providing an experimental basis for determining the safety of food additives. All of the food additives tested were observed to decrease the growth of HepG2 cells in a dose-dependent manner. Sunset yellow and sodium sulfite had IC50 values of 1.06, and 0.30 g/L at 24 h, respectively. HCA showed that both sunset yellow and sodium sulfite had synergistic effects on cell number, membrane permeability, mitochondrial membrane potential, intracellular calcium level, oxidative stress, and high dose group DNA damage.
研究领域:
食品安全
·
毒理学
·
细胞生物学
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）